- Accession Number
Agents that induce NARCOSIS. Narcotics include agents that cause somnolence or induced sleep (STUPOR); natural or synthetic derivatives of OPIUM or MORPHINE or any substance that has such effects. They are potent inducers of ANALGESIA and OPIOID-RELATED DISORDERS.
Drug Drug Description Tapentadol An opioid used to manage severe pain that has not responded to non-opioid medications, and for which opioid analgesic therapy is appropriate. Tramadol A centrally-acting opioid agonist and SNRI (serotonin/norepinephrine reuptake inhibitor) used for the management of moderate to severe pain in adults. Morphine An opioid agonist used for the relief of moderate to severe acute and chronic pain. Codeine An opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated. Hydromorphone An opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated. Methadone An opioid analgesic indicated for management of severe pain that is not responsive to alternative treatments. Also used to aid in detoxification and maintenance treatment of opioid addiction. Meperidine An opioid agonist with analgesic and sedative properties used to manage severe pain. Oxycodone An opioid used in the management of moderate to severe pain. Butorphanol An opioid agonist-antagonist used to treat moderate to severe pain. Dextropropoxyphene An opioid analgesic used to treat mild to moderate pain. Pentazocine An analgesic used to treat moderate to severe pain. Sufentanil An opioid used to induce and maintain anesthesia, to act as an analgesic in labor and delivery, and to treat severe, acute pain. Alfentanil An opioid agonist used to induce and maintain anesthesia, as well as an analgesic. Fentanyl An opioid analgesic used in anesthesia, for breakthrough cancer pain, or round the clock pain management. Nalbuphine An opioid agonist-antagonist used to treat pain, for pre and postoperative analgesia, and for analgesia in labor and delivery. Levorphanol An opioid analgesic used to treat moderate to severe pain. Remifentanil An opioid analgesic used in anesthesia. Buprenorphine A partial opioid agonist used for management of severe pain that is not responsive to alternative treatments. Also used for maintenance treatment of opioid addiction. Hydrocodone An opioid agonist used as an analgesic and antitussive agent. Oxymorphone An opioid analgesic used in the management of moderate-to-severe pain and for analgesic therapies. Dezocine Indicated in the treatment of moderate to severe pain. Levacetylmethadol For the treatment and management of opiate dependence. It is sometimes used to treat severe pain in terminal patients. Methadyl acetate Used mainly in the treatment of narcotic dependence. Dihydroetorphine Not Available Diamorphine An opioid analgesic agent used in the relief of severe pain associated with surgical procedures, myocardial infarction or pain in the terminally ill and for the relief of dyspnea in acute pulmonary edema. Ethylmorphine An opioid analgesic and antitussive agent used to reduce coughs caused by colds and lung infections in combination with codeine. Etorphine Etorphine is only available for its use in veterinary. This main usage is related to the immobilization of large mammals. Ecgonine Not Available Dextromoramide An opioid analgesic structurally related to methadone and used in the treatment of severe pain. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1070) Carfentanil Carfentanil is similar (but more potent) to the opioid analgesic fentanyl. It is used as a tranquilizer for large animals. Drotebanol Not Available Dihydrocodeine An opioid analgesic agent used for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate. Alphacetylmethadol A narcotic analgesic with a long onset and duration of action. It is used mainly in the treatment of narcotic dependence. [PubChem] Dihydromorphine Dihydromorphine is an opioid analgesic used for moderate to severe pain relief. Methylecgonine Not Available Ketobemidone For the treatment of all types of severe pain, such as postoperative, cancer, kidney stones and fractures. DPDPE A heterodetic cyclic peptide that is a cyclic enkephalin analogue, having D-penicillaminyl residues located at positions 2 and 5, which form the heterocycle via a disulfide bond. Lofentanil Lofentanil is an analog of fentanyl and is one of the most potent opioids available today. It displays most similarity to carfentanil (4-carbomethoxyfentanyl) and is considered to be slightly more... Opium A medication used to treat moderate to severe pain. Normethadone An opioid antitussive used to treat a cough associated with inflamed mucosa. Piritramide A synthetic opioid used in the treatment of severe pain. Alphaprodine Not Annotated Meptazinol Not Annotated Phenoperidine Not Annotated Phenazocine Not Annotated Tilidine A synthetic opioid indicated in the treatment of severe pain. Carfentanil, C-11 Carfentanil, C-11 is under investigation in clinical trial NCT01899170 (Towards Individualized Deep Brain Stimulation Treatment of Chronic Neuropathic Pain). Desomorphine Not Available Nicomorphine Not Annotated Oliceridine A biased opioid agonist indicated for the management of severe acute pain in adult patients. Through preferential activation of G-protein-coupled signalling pathways, oliceridine provides analgesic effect with a comparable or improved safety profile over conventional opioid agonists.
- Drugs & Drug Targets