Nicotinic Antagonists
- Name
- Nicotinic Antagonists
- Accession Number
- DBCAT000919
- Description
Drugs that bind to nicotinic cholinergic receptors (RECEPTORS, NICOTINIC) and block the actions of acetylcholine or cholinergic agonists. Nicotinic antagonists block synaptic transmission at autonomic ganglia, the skeletal neuromuscular junction, and at central nervous system nicotinic synapses.
- Drugs
Drug Drug Description Agmatine Agmatine is being studied experimentally for several indications such as cardioprotection, diabetes, decreased kidney function, neuroprotection (stroke, severe CNS injuries, epilepsy, glaucoma, and neuropathic pain), and psychiatric conditions (depression, anxiety,... Alcuronium A non-depolarizing skeletal muscle relaxant similar to tubocurarine. It is used as an anesthesia adjuvant. Amantadine A medication used to treat dyskinesia in Parkinson's patients receiving levodopa, as well as extrapyramidal side effects of medications. Amobarbital A barbiturate derivative used for the induction of sedation during procedures, short-term management of insomnia, and acute management of refractory tonic-clonic seizures. Aprobarbital Aprobarbital is a barbiturate derivative synthesized in the 1920s by Ernst Preiswerk. It was determined that the substance was capable of demonstrating sedative, hypnotic, and anticonvulsant effects. A primary treatment... Atracurium A neuromuscular blocker indicated to relax muscles during mechanical ventilation under general anesthesia or intubation. Atracurium besylate A non-depolarizing neuromuscular blocker used to facilitate endotracheal intubation and relax skeletal muscles during surgery. Barbital A long-acting barbiturate that depresses most metabolic processes at high doses. It is used as a hypnotic and sedative and may induce dependence. Barbital is also used in veterinary practice... Biperiden A muscarinic receptor antagonist used to treat parkinsonism and control extrapyramidal side effects of neuroleptic drugs. Butabarbital A barbiturate drug used as a sedative and hypnotic. Butalbital A barbiturate drug used for symptomatic treatment of tension-type headache in various combinations with acetaminophen, aspirin, caffeine, and codeine. Butobarbital For the treatment of insomnia. Chlorisondamine Not Annotated Cisatracurium A skeletal muscle relaxant used to facilitate tracheal intubation, muscle relaxation in surgery, or mechanical ventilation. Dextromethorphan An NMDA receptor antagonist used to treat cases of dry cough. Dihydro-2-thioxo-5-((5-(2-(trifluoromethyl)phenyl)-2-furanyl)methyl)-4,6(1H,5H)-pyrimidinedione Not Available Doxacurium A nondepolarizing neuromuscular blocking agent used as an adjunct to general anesthesia to facilitate tracheal intubation, and to provide skeletal muscle relaxation during surgical procedures. Fluoxetine A selective serotonin reuptake inhibitor used to treat major depressive disorder, bulimia, OCD, premenstrual dysphoric disorder, panic disorder, and bipolar I. Gallamine Not Annotated Gallamine triethiodide A nondepolarizing nerve blocker used in addition to anesthesia to cause skeletal muscle relaxation. Gantacurium Investigated for use/treatment in anesthesia (unspecified). Heptabarbital Used mainly for sedation and hypnosis. Hexafluronium Used as an adjunct with succinylcholine (or suxamethonium chloride) to prolong muscle relaxation and to prevent succinylcholine-induced muscle fasciculations. Hexamethonium A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been... Hexobarbital For the induction of anesthesia prior to the use of other general anesthetic agents and for induction of anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful... Homidium Homidium is a group II compound with trypanocidal effects. Isoflurane An inhaled general anesthetic used in surgery. Levacetylmethadol For the treatment and management of opiate dependence. It is sometimes used to treat severe pain in terminal patients. Mecamylamine A nicotine antagonist used to treat moderate to severe essential hypertension and uncomplicated malignant hypertension. Methadone An opioid analgesic indicated for management of severe pain that is not responsive to alternative treatments. Also used to aid in detoxification and maintenance treatment of opioid addiction. Metharbital Metharbital is used for the treatment of epilepsy. Methylphenobarbital For the relief of anxiety, tension, and apprehension, also used as an anticonvulsant for the treatment of epilepsy. Metocurine Metocurine is a muscle relaxant. Metocurine iodide For use as an anesthesia adjunct to induce skeletal muscle relaxation and to reduce the intensity of muscle contractions in convulsive therapy. Mivacurium A short-acting non-depolarizing neuromuscular blocking agent used to induce anesthesia during intubation and promote skeletal muscle relaxation during surgery or mechanical ventilation. Pancuronium A neuromuscular blocker used as an adjunct to general anesthesia to facilitate tracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Pempidine Pempidine is a small molecule drug. Pempidine has a monoisotopic molecular weight of 155.17 Da. Pentobarbital A barbiturate drug used to induce sleep, cause sedation, and control certain types of seizures. Pentolinium Used to produce controlled hypotension during surgical procedures and in hypertensive crises. Phenobarbital A long-lasting barbiturate and anticonvulsant used in the treatment of all types of seizures, except for absent seizures. Pipecuronium A nondepolarizing neuromuscular blocking agent used to relax muscles during anesthesia and surgical procedures. Primidone An antiepileptic used to treat grand mal, psychomotor, and focal epileptic seizures. Procaine A local anesthetic used for anesthesia, peripheral nerve block, and spinal nerve block. Rocuronium A vecuronium analog used to facilitate tracheal intubation and to relax skeletal muscles during surgery. Secobarbital A barbiturate used for the short-term treatment of insomnia. Talbutal For use as a sedative and hypnotic. Thiopental A barbiturate used to induce general anesthesia, treat convulsions, and reduce intracranial pressure. Trimethaphan For the controlled reduction of blood pressure during surgery and in the treatment of hypertensive emergencies. Tubocurarine Tubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid. Curare is one of the names used to describe plant-derived poisons used by indigenous South Americans to... Vecuronium A nondepolarizing neuromuscular blocking agent used to relax muscles or as an adjunct in general anesthesia during surgical procedures. - Drugs & Drug Targets