Clostridium Difficile Infection (CDI)

Also known as: Infections, Clostridium Difficile / Clostridium Difficile Infections / Clostridium Difficile Infection / Clostridial disease / Clostridium difficile infection (disorder) / Clostridioides difficile infection (disorder)

Drug	Drug Name	Drug Description
DB00618	Demeclocycline	A tetracycline antibiotic used to treat a wide variety of susceptible bacterial infections.
DB06149	Teicoplanin	A glycopeptide antibiotic with a similar mechanism of action and spectrum of activity to vancomycin used to treat various infections caused by gram-positive bacteria.

Drug	Drug Name	Target	Type
DB00618	Demeclocycline	30S ribosomal protein	target
DB00618	Demeclocycline	Vasopressin V2 receptor	target
DB06149	Teicoplanin	D-Ala-D-Ala moiety of NAM/NAG peptide subunits of peptidoglycan	target

Drug	Drug Name	Phase	Status	Count
DB12262	CRS-3123	1	Completed	1
DB11847	Cadazolid	1	Completed	1
DB00338	Omeprazole	1	Completed	1
DB00512	Vancomycin	1	Completed	2
DB11876	Alanyl glutamine	2	Recruiting	1
DB11876	Alanyl glutamine	2	Terminated	1
DB13140	Bezlotoxumab	2	Recruiting	1
DB11847	Cadazolid	2	Completed	1
DB08874	Fidaxomicin	2	Completed	1
DB16189	Ibezapolstat	2	Recruiting	1
DB00130	L-Glutamine	2	Recruiting	1
DB12892	MGB-BP-3	2	Completed	1
DB15308	Ridinilazole	2	Completed	2
DB12076	Surotomycin	2	Completed	1
DB00512	Vancomycin	2	Completed	4
DB00512	Vancomycin	2	Recruiting	2
DB11847	Cadazolid	2 / 3	Terminated	1
DB00836	Loperamide	2 / 3	Unknown Status	1
DB00916	Metronidazole	2 / 3	Terminated	1
DB00916	Metronidazole	2 / 3	Unknown Status	1
DB00512	Vancomycin	2 / 3	Terminated	1
DB00512	Vancomycin	2 / 3	Unknown Status	1
DB16376	Actoxumab	3	Completed	1
DB13140	Bezlotoxumab	3	Completed	3
DB11847	Cadazolid	3	Completed	2
DB08874	Fidaxomicin	3	Completed	1
DB08874	Fidaxomicin	3	Terminated	1
DB12076	Surotomycin	3	Completed	2
DB00512	Vancomycin	3	Completed	5
DB00512	Vancomycin	3	Not Yet Recruiting	1
DB00512	Vancomycin	3	Recruiting	2
DB01294	Bismuth subsalicylate	4	Withdrawn	1
DB08874	Fidaxomicin	4	Completed	3
DB08874	Fidaxomicin	4	Withdrawn	2
DB01220	Rifaximin	4	Completed	1
DB00512	Vancomycin	4	Completed	4
DB00512	Vancomycin	4	Recruiting	2
DB00512	Vancomycin	4	Terminated	1
DB00512	Vancomycin	4	Unknown Status	2
DB13140	Bezlotoxumab	Not Available	Completed	1
DB13140	Bezlotoxumab	Not Available	Unknown Status	1
DB08874	Fidaxomicin	Not Available	Completed	1
DB08874	Fidaxomicin	Not Available	Enrolling by Invitation	1
DB08874	Fidaxomicin	Not Available	Unknown Status	1
DB15823	Lactobacillus acidophilus	Not Available	Unknown Status	1
DB16540	Lactobacillus delbrueckii bulgaricus	Not Available	Unknown Status	1
DB00338	Omeprazole	Not Available	Unknown Status	1
DB00512	Vancomycin	Not Available	Active Not Recruiting	1
DB00512	Vancomycin	Not Available	Completed	1
DB00512	Vancomycin	Not Available	Unknown Status	2