Refractory Lymphoblastic Leukemia, Acute, Childhood

Also known as: Refractory Childhood Acute Lymphoblastic Leukemia

Drug	Drug Name	Drug Description
DB00444	Teniposide	A cytotoxic drug used as an adjunct for chemotherapy induction in the treatment of refractory childhood acute lymphoblastic leukemia.

Drug	Drug Name	Target	Type
DB00444	Teniposide	DNA topoisomerase 2-alpha	target
DB00444	Teniposide	Cytochrome P450 2C19	enzyme
DB00444	Teniposide	Cytochrome P450 2C9	enzyme
DB00444	Teniposide	Cytochrome P450 3A4	enzyme
DB00444	Teniposide	Multidrug resistance-associated protein 6	transporter
DB00444	Teniposide	ATP-binding cassette sub-family G member 2	transporter
DB00444	Teniposide	Cytochrome P450 3A5	enzyme

Drug	Drug Name	Phase	Status	Count
DB01254	Dasatinib	1	Terminated	1
DB06132	Nivolumab	1	Terminated	1
DB09035	Nivolumab	1	Terminated	1
DB17364	AUTO3	1 / 2	Completed	1
DB01073	Fludarabine	2	Completed	1
DB16620	Methopterin	2	Completed	1
DB00563	Methotrexate	2	Completed	1
DB00864	Tacrolimus	2	Completed	1
DB04572	Thiotepa	2	Completed	1
DB03754	Tromethamine	2	Completed	1