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Tranylcypromine Amine Oxidase Norepinephrine Antidepressant Action Pathway
smpdb.ca/view/SMP0126672Drug actionTranylcypromine is a non-hydrazine monoamine oxidase inhibitor belonging to the class of antidepressants called MAOIs. This drug is indicated in the treatment of major depression, dysthymic disorder, and atypical depression. It also is u...
Enzymes: Aromatic-L-amino-acid decarboxylasePhenelzine Amine Oxidase Norepinephrine Antidepressant Action Pathway
smpdb.ca/view/SMP0126682Drug actionPhenelzine, also known as Nardil, is a monoamine oxidase inhibitor (MAOIs). This drug is used as an antidepressant and it is also effective in the treatment of panic disorder and social anxiety disorder. The monoamine oxidase is an enzym...
Enzymes: Aromatic-L-amino-acid decarboxylaseMinaprine Amine oxidase Norepinephrine Antidepressant Action Pathway
smpdb.ca/view/SMP0126684Drug actionMinaprine is an amino-phenylpyridazine antidepressant. It is indicated in the treatment of various depressive states. Minaprine acts on many targets in the neurons. Firstly, this drug binds as an antagonist to the serotonin type 2 recept...
Enzymes: Aromatic-L-amino-acid decarboxylaseMoclobemide Amine Oxidase Norepinephrine Antidepressant Action Pathway
smpdb.ca/view/SMP0126685Drug actionMoclobemide is a reversible monoamine oxidase inhibitor (MAOIs) selective for the isoform A (RIMA). This molecule is indicated in the treatment of major depressive disorder (MDD) and bipolar disorder. he monoamine oxidase is an enzyme th...
Enzymes: Aromatic-L-amino-acid decarboxylasePargyline Action Pathway
smpdb.ca/view/SMP0126708Drug actionPargyline is a monoamine oxidase B inhibitor (MAOIs). This drug has antihypertensive properties and is, thus, indicated in the treatment of moderate to severe hypertension. Pargyline inhibits the breakdown of monoamine neurotransmitters,...
Enzymes: Aromatic-L-amino-acid decarboxylaseSolriamfetol Action Pathway
smpdb.ca/view/SMP0126346Drug actionSolriamfetol, also known as Sunosi, is a dopamine and norepinephrine reuptake inhibitor (DNRI). This drug is indicated for the daytime treatment of sleepiness associated with narcolepsy or obstructive sleep apnea. Solriamfetol was given ...
Enzymes: Aromatic-L-amino-acid decarboxylaseIron
go.drugbank.com/drugs/DB01592ApprovedInvestigationalA metallic element found in certain minerals, in nearly all soils, and in mineral waters. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems. Its chief functions are in the transp...
Mixtures: Folivane-Plus with Ascorbic Acid PrecursorsCategories: iron, vitamin B12 and folic acid, iron, multivitamins and folic acidDeficiency, Vitamin D
go.drugbank.com/conditions/DBCOND0044543Drugs: Ascorbic acid · Calcium · Calcium citrate · Cholecalciferol · Cod liver oil · Ergocalciferol +3 moreThe Oncogenic Action of Succinate
smpdb.ca/view/SMP0002292DiseaseHypoxia-inducible factor In many tumours, oxygen availability becomes limited (hypoxia) very quickly during cancer development. The major regulator of the response to hypoxia is the HIF transcription factor. Under normal oxygen levels, t...
Immunometabolism Pathway (Viral Activation)
smpdb.ca/view/SMP0125488DiseaseThe reduction in essential amino acids is intended to “starve” the invading viruses (and other pathogens) of the amino acids they need to reproduce [4]. … and the production of fatty acids and acylcarnitines (needed for lipid synthesis).
Enzymes: Low affinity cationic amino acid transporter 2