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Metabolism and Physiological Effects of Oxalic acid
smpdb.ca/view/SMP0124875MetabolicOxalic acid (oxalate) is a strong dicarboxylic acid that is also a known uremic toxin. It is produced in the body by metabolism of glyoxylic acid or ascorbic acid. Glyoxylate is generated through glycine and hydroxyproline catabolism and...
Drugs: Pyridoxal phosphate · Ascorbic acid · Succinic acid · Glutamic acid · Glycine · Proline +4 moreEnzymes: Sodium- and chloride-dependent transporter XTRP3, Sodium- and chloride-dependent creatine transporter 1Dopamine Action Pathway
smpdb.ca/view/SMP0125137Drug actionIn the synapse, dopamine prevents the re-uptake of norepinephrine by inhibiting Sodium-dependent noradrenaline transporter. … Dopamine enters the sympathetic neuron through a sodium-dependent dopamine transporter.. In the neuron, it is catalyzed by Dopamine beta-hydroxylase to synthesize norepinephrine.
Enzymes: Sodium/calcium exchanger 1, Sodium-dependent dopamine transporterDopamine Action Pathway
smpdb.ca/view/SMP0127069PhysiologicalIn the synapse, dopamine prevents the re-uptake of norepinephrine by inhibiting Sodium-dependent noradrenaline transporter. … Dopamine enters the sympathetic neuron through a sodium-dependent dopamine transporter.. In the neuron, it is catalyzed by Dopamine beta-hydroxylase to synthesize norepinephrine.
Enzymes: Sodium/calcium exchanger 1, Sodium-dependent dopamine transporterMethyl alcohol poisoning
go.drugbank.com/conditions/DBCOND0023035Imipramine Action Pathway (New)
smpdb.ca/view/SMP0126359Drug actionImipramine binds to the sodium-dependent serotonin transporter and to the sodium-dependent norepinephrine transporter reducing the reuptake of norepinephrine and serotonin by presynaptic neurons.
Drugs: Pyridoxal phosphate · Ascorbic acid · Tyrosine · Tryptophan · Sapropterin · Norepinephrine +7 moreEnzymes: Sodium-dependent serotonin transporter, Sodium-dependent noradrenaline transporterTrimipramine Action Pathway
smpdb.ca/view/SMP0126348Drug actionBy binding to the sodium-dependent serotonin transporter and the sodium-dependent noradrenaline transporter, trimipramine fulfill its functions.
Drugs: Pyridoxal phosphate · Ascorbic acid · Tyrosine · Tryptophan · Sapropterin · Norepinephrine +7 moreEnzymes: Sodium-dependent serotonin transporter, Sodium-dependent noradrenaline transporterNortriptyline Action Pathway
smpdb.ca/view/SMP0126345Drug actionIt is possible by its binding to the sodium-dependent noradrenaline transporter and to the sodium-dependent serotonin transporter.
Drugs: Pyridoxal phosphate · Ascorbic acid · Tyrosine · Tryptophan · Sapropterin · Norepinephrine +7 moreEnzymes: Sodium-dependent serotonin transporter, Sodium-dependent noradrenaline transporterDesipramine Action Pathway (New)
smpdb.ca/view/SMP0126352Drug actionIt binds to the sodium-dependent noradrenaline transporter and to the sodium-dependent serotonin transporter of the presynaptic neurons.
Drugs: Pyridoxal phosphate · Ascorbic acid · Tyrosine · Tryptophan · Sapropterin · Norepinephrine +7 moreEnzymes: Sodium-dependent serotonin transporter, Sodium-dependent noradrenaline transporterDoxepin Norepinephrine Reuptake Inhibitor Action Pathway (New)
smpdb.ca/view/SMP0126355Drug actionDoxepin binds to the sodium-dependent noradrenaline transporter and to the sodium-dependent serotonin transporter.
Drugs: Pyridoxal phosphate · Ascorbic acid · Tyrosine · Tryptophan · Sapropterin · Norepinephrine +7 moreEnzymes: Sodium-dependent serotonin transporter, Sodium-dependent noradrenaline transporter