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Displaying results 81 - 90 of 2725 in total
  1. Drug

    Procarbazine

    go.drugbank.com/drugs/DB01168
    ApprovedInvestigational

    An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.

  2. Pathway

    Sarcosine Oncometabolite Pathway

    smpdb.ca/view/SMP0002313
    Disease

    consisting of S-adenosylmethionine synthase and methionine adenosyltransferase. … A separate set of reactions outside of the mitochondria begins with the L-methionine produced by betaine—homocysteine S-methyltransferase 1, which is then converted to S-adenosylmethionine by a complex

    Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Choline · Serine · Methionine +10 more
    Enzymes: Methionine adenosyltransferase 2 subunit beta
  3. Pathway

    Metabolism and Physiological Effects of Dimethylglycine

    smpdb.ca/view/SMP0124873
    Metabolic

    Dimethylglycine (DMG) is an amino acid derivative found in the cells of all plants and animals and can be obtained in the diet in small amounts from grains and meat. The human body produces DMG when metabolizing choline into glycine. Cho...

    Drugs: Choline · Methionine · NADH · Zinc · N,N-dimethylglycine · Flavin adenine dinucleotide +1 more
  4. Drug

    Ancestim

    go.drugbank.com/drugs/DB09103
    ApprovedWithdrawn

    166 amino acid protein produced by E. coli with an amino acid sequence that is identical to the natural sequence predicted from human DNA sequence analysis, except for the addition of an N-terminal methionine

  5. Drug

    Homocysteine

    go.drugbank.com/drugs/DB04422
    Investigational

    Homocysteine is a thiol-containing amino acid formed by a demethylation of methionine.

  6. Indication

    Malnutrition; Protein

    go.drugbank.com/conditions/DBCOND0082006
    Drugs: D-Methionine · Plasma protein fraction (human)
  7. Drug

    5-methyltetrahydrofolic acid

    go.drugbank.com/drugs/DB04789
    InvestigationalNutraceutical

    (also called methionine synthases). … It is generated by methylenetetrahydrofolate reductase from 5,10-methylenetetrahydrofolate and used to recycle homocysteine back to methionine by 5-methyltetrahydrofolate-homocysteine methyltransferases

  8. Drug

    Acetylcarnitine

    go.drugbank.com/drugs/DB08842
    ApprovedInvestigational

    In human plasma and tissues, acetylcarnitine is the most predominant acylated ester of carnitine, which is an amino acid derivative that is made in the kidney, liver, and brain from lysine and methionine

  9. Indication

    Hepatic Encephalopathy

    go.drugbank.com/conditions/DBCOND0000786
    Drugs: Lactitol · Lactulose · Methionine · Ornithine · Rifaximin · Sodium bisulfite +1 more
  10. Drug

    Nitroxoline

    go.drugbank.com/drugs/DB01422
    Experimental

    Nitroxoline is a urinary antibacterial agent active against susceptible gram-positive and gram-negative organisms commonly found in urinary tract infections. It is a hydroxyquinoline derivative unrelated to other classes of drugs. Nitrox...