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Zinc
go.drugbank.com/drugs/DB01593ApprovedInvestigationalUnderstanding the mechanisms that control brain zinc homeostasis is, therefore, imperative to the development of preventive and treatment regimens for these and other neurological disorders [A32465]. … Zinc deficiency is associated with anemia, short stature, hypogonadism, impaired wound healing, and geophagia. It is identified by the symbol _Zn_ [L2098].
Synonyms: Zinc, Zinc, chelatedMixtures: Calcium & Magnesium Plus Potassium, Zinc, & Manganese, Calcium & Magnesium With Potassium, Zinc, Manganese & Vitamin DMagnesium
go.drugbank.com/drugs/DB14513ApprovedInvestigationalMagnesium is classified as an alkaline earth metal and has 2 hydration shells. … [A19349] The element can be found in abundance in the hydrosphere and in mineral salts such as dolomite and magnesium carbonate.
Synonyms: Magnesium, Magnesium powderMixtures: Calcium & Magnesium Plus Potassium, Zinc, & Manganese, Calcium & Magnesium With Potassium, Zinc, Manganese & Vitamin DManganese cation
go.drugbank.com/drugs/DB06757ApprovedInvestigationalNutraceuticalManganese is a transition metal that was first described in the 19th and 20th centuries. … [A263657, A263667] Manganese intake primarily occurs through the diet,[A263687] as it is found at low levels in many food sources and water.
Synonyms: Manganese cation, MANGANESE(2+)Salts: Manganese chloride, Manganese sulfateFructose and Mannose Degradation
smpdb.ca/view/SMP0000064MetabolicFructose causes less of an insulin response compared to glucose and thus may be a preferred sugar for diabetics. … Fructose and mannose are monosaccharides that can be found in many foods. Fructose can join with glucose to form sucrose. Mannose can be converted to glucose. Both may be used as food sweeteners.
Glycine and Serine Metabolism
smpdb.ca/view/SMP0000004MetabolicThis pathway describes the synthesis and breakdown of several small amino acids, including glycine, serine, and cysteine. … All of these compounds share common intermediates and almost all can be biosynthesized from one another. Serine and glycine are not essential amino acids and can be synthesized from several routes.
Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Pyruvic acid · Arginine · Adenosine phosphate +26 morePantothenate and CoA Biosynthesis
smpdb.ca/view/SMP0000027MetabolicPantothenic acid, pantetheine 4’-phosphate and pantetheine are all found in red blood cells. … It is a precursor of coenzyme A, which is an essential part of many reactions in the body, specifically important in the production of compounds like cholesterol and different fatty acids.
Phenylalanine and Tyrosine Metabolism
smpdb.ca/view/SMP0000008Metabolicinto polypeptides (via tyrosyl tRNA synthetase and phenylalyl tRNA synthetase) and the conversion of phenylalanine to tyrosine via phenylalanine hydroxylase. … Tyrosine can be converted into L-DOPA, which is further converted into dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline).
Drugs: Pyridoxal phosphate · Phenylalanine · Adenosine phosphate · Tyrosine · Glutamic acid · ATP +11 moreMetabolism and Physiological Effects of Uridine
smpdb.ca/view/SMP0124871MetabolicMore specifically, uridine is a nucleoside consisting of uracil and D-ribose and a component of RNA. … L-glutamine is first converted to carbamoyl phosphate then to N-Carbamoyl-L-aspartate and finally to dihydroorotate by the CAD protein (carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and
Apoptotic DNA Fragmentation and Tissue Homeostasis
smpdb.ca/view/SMP0063772SignalingICAD and CAD exist in the nucleus in normal cells and is a major endonuclease in apoptosis. Its activation is normally caspase dependent. … EndoG resides in mitochondria in normal cells and travels to the nucleus, where it fragments chromosomal DNA upon activation of apoptosis.
Drugs: ZincMetabolism and Physiological Effects of Xanthine
smpdb.ca/view/SMP0124865MetabolicThe purines are guanine and adenine. These undergo metabolism in the liver to form xanthine. Adenine forms adenosine through the enzyme purine nucleoside phosphorylase. … Adenosine then reacts with water to form inosine and ammonia using the enzyme adenosine deaminase. Inosine goes on to form hypoxanthine through the enzyme purine nucleoside phosphorylase.