Displaying drugs 351 - 375 of 11465 in total
Pentastarch
Pentastarch is an artificial colloid (hydroxyethyl starch derivative). Pentastarch is characterized by presenting five hydroxyethyl groups, which signifies an approximate 50% hydroxyethylation. It is sold under the name Pentaspan by Bristol-Myers Squibb and is used for fluid resuscitation. When administered, pentastarch remains mainly in the circulatory system and hence, it...
Approved
Investigational
Matched Description: … When administered, pentastarch remains mainly in the circulatory system and hence, it is considered a …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Indocyanine green acid form
Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide, inner salt, sodium salt. Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. Each vial of Indocyanine Green for...
Approved
Investigational
Matched Description: … Indocyanine Green is a water soluble, tricarbocyanine dye with a peak spectral absorption at 800 nm. ... Indocyanine Green for Injection USP has a pH of approximately 6.5 when reconstituted. ... Each vial of Indocyanine Green for Injection USP contains 25 mg of Indocyanine Green as a sterile lyophilized …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Boric acid
Boric acid, also known as hydrogen borate, is a weak monobasic Lewis acid of boron with the chemical formula H3BO3. Boric acid is typically utilized in industrial processing and manufacturing, but is also used as an additive in pharmaceutical products, cosmetics, lotions, soaps, mouthwash, toothpaste, astringents, and eyewashes . It...
Approved
Matched Description: … Boric acid, also known as hydrogen borate, is a weak monobasic Lewis acid of boron with the chemical …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Phenylpropanolamine
Phenylpropanolamine is a sympathomimetic agent that acts as a nonselective adrenergic receptor agonist and norepinephrine reuptake inhibitor. It has been used as a decongestant and appetite suppressant. Currently, it is withdrawn from the market in Canada and the United States due to the risk for hemorrahgic strokes.
Approved
Vet approved
Withdrawn
Matched Description: … Phenylpropanolamine is a sympathomimetic agent that acts as a nonselective adrenergic receptor agonist ... It has been used as a decongestant and appetite suppressant. …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Pomalidomide
Pomalidomide, an analogue of thalidomide, is an immunomodulatory antineoplastic agent. FDA approved on February 8, 2013.
Approved
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Etonogestrel
Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel. The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in 2001.
Approved
Investigational
Matched Iupac: … -1-ethynyl-1-hydroxy-10-methylidene-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically …
Matched Description: … Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically …
Ethynodiol diacetate
A synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive. Although etynodiol or ethynodiol are sometimes used as a synonym for ethynodiol diacetate, what is usually being referred to is actually ethynodiol diacetate and not ethynodiol (which is a separate drug that has never been...
Approved
Matched Iupac: … -7-(acetyloxy)-1-ethynyl-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … A synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive ... being referred to is actually ethynodiol diacetate and not ethynodiol (which is a separate drug that ... Although etynodiol or ethynodiol are sometimes used as a synonym for ethynodiol diacetate, what is usually …
Matched Description: … A synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive ... being referred to is actually ethynodiol diacetate and not ethynodiol (which is a separate drug that ... Although etynodiol or ethynodiol are sometimes used as a synonym for ethynodiol diacetate, what is usually …
Norgestimate
Norgestimate was first described in the literature in 1977. It was developed by Ortho Pharmaceutical Corporation as part of an effort to develop new hormonal contraceptives with reduced adverse effects. It is commonly formulated with ethinylestradiol as a combined oral contraceptive that can also be used to treat moderate acne...
Approved
Investigational
Matched Iupac: … 11a-ethyl-1-ethynyl-7-(hydroxyimino)-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … [A191068] It is commonly formulated with [ethinylestradiol] as a combined oral contraceptive that can …
Matched Description: … [A191068] It is commonly formulated with [ethinylestradiol] as a combined oral contraceptive that can …
Hydroxyprogesterone caproate
Hydroxyprogesterone caproate is a synthetic steroid hormone that is similar to medroxyprogesterone acetate and megestrol acetate. It is an ester derivative of 17α-hydroxyprogesterone formed from caproic acid (hexanoic acid). Hydroxyprogesterone caproate was previously marketed under the trade name Delalutin by Squibb, which was approved by the U.S. Food and Drug...
Approved
Investigational
Matched Iupac: … 11aS)-1-acetyl-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … history of preterm delivery, sparking a pricing controversy. ... Hydroxyprogesterone caproate is a synthetic steroid hormone that is similar to medroxyprogesterone acetate ... (previously named as Gestiva) on February 4, 2011 for prevention of preterm delivery in women with a …
Matched Description: … history of preterm delivery, sparking a pricing controversy. ... Hydroxyprogesterone caproate is a synthetic steroid hormone that is similar to medroxyprogesterone acetate ... (previously named as Gestiva) on February 4, 2011 for prevention of preterm delivery in women with a …
Terlipressin
Terlipressin is a synthetic analogue of vasopressin, which is an endogenous neurohormone that acts as a vasoconstrictor. It is a prodrug of lypressin, or lysine vasopressin. Compared to endogenous vasopressin, terlipressin has a longer half life and increased selectivity for the V1 receptor. As a potent vasopressor, terlipressin has been...
Approved
Investigational
Matched Description: … a vasoconstrictor. ... [A2601] It is a prodrug of [lypressin], or lysine vasopressin. ... Terlipressin is a synthetic analogue of vasopressin, which is an endogenous neurohormone that acts as …
Abemaciclib
Abemaciclib is an antitumor agent and dual inhibitor of cyclin-dependent kinases 4 (CDK4) and 6 (CDK6) that are involved in the cell cycle and promotion of cancer cell growth in case of unregulated activity. On September 28, 2017, FDA granted approval of abemaciclib treatment under the market name Verzenio for...
Approved
Investigational
Matched Categories: … MATE 1 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Oxytetracycline
A tetracycline analog isolated from the actinomycete streptomyces rimosus and used in a wide variety of clinical conditions.
Approved
Investigational
Vet approved
Matched Description: … A tetracycline analog isolated from the actinomycete streptomyces rimosus and used in a wide variety …
Vericiguat
Vericiguat is a direct stimulator of soluble guanylate cyclase (sGC) used in the management of systolic heart failure to reduce mortality and hospitalizations. A key component of the NO-sGC-cGMP signaling pathway that helps to regulate the cardiovascular system, sGC enzymes are intracellular enzymes found in vascular smooth muscle cells (amongst...
Approved
Investigational
Matched Description: … [A227458,A227488] Cyclic GMP acts as a second messenger, activating a number of downstream signaling ... [A227458] As a direct stimulator of sGC, vericiguat mitigates the need for a functional NO-sGC-cGMP axis ... Vericiguat is a direct stimulator of soluble guanylate cyclase (sGC) used in the management of systolic …
Interferon alfa-n3
Purified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD).
Approved
Investigational
Disulfiram
A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms...
Approved
Matched Description: … A carbamate derivative used as an alcohol deterrent. ... It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism …
Pegaptanib
Pegaptanib is a polynucleotide aptamer. Pegatinib aids neovascular age-related macular degeneration by binding to VEGF which in order reduces angiogenesis and vessel permeability.
Pegaptanib was granted FDA approval on 17 September 2004.
Approved
Investigational
Matched Description: … Pegaptanib is a polynucleotide aptamer. …
Matched Categories: … Vascular Endothelial Growth Factor A …
Matched Categories: … Vascular Endothelial Growth Factor A …
Perflubutane
Perflubutane has been used in trials studying the diagnostic of Liver Mass, Liver Diseases, Liver Metastasis, Portal Hypertension, and Peripheral Artery Disease. It is a cardiovascular drug designed to enable ultrasound to compete more effectively with nuclear stress testing; currently the leading procedure for detecting coronary heart disease.
Approved
Investigational
Matched Description: … It is a cardiovascular drug designed to enable ultrasound to compete more effectively with nuclear stress …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Indocyanine green
Approved
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Motixafortide
Motixafortide is a cyclic peptide hematopoietic stem cell mobilizer used to improve stem cell collection prior to autologous transplantation. Hematopoietic stem cell transplantation (HSCT) is commonly employed in the context of hematologic cancers - high-dose chemotherapy regimens destroy cancerous blood cells, which are then replaced via infusion of the patient's...
Approved
Investigational
Matched Description: … Motixafortide is a cyclic peptide hematopoietic stem cell mobilizer used to improve stem cell collection ... previously approved [plerixafor], motixafortide is an inhibitor of C-X-C Motif Chemokine Receptor 4 (CXCR4), a …
Caffeine
Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness. Caffeine is similar in chemical structure to Theophylline and Theobromine.[A187691,L9851] It can be sourced from coffee beans, but also occurs naturally in...
Approved
Matched Description: … Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory ... [T716] Caffeine is also used in a variety of cosmetic products and can be administered topically, orally ... Premature birth can lead to apnea and bronchopulmonary dysplasia, a condition that interferes with lung …
Matched Mixtures name: … Pancold A ... Saridon - A ... A & C Tablets With Codeine 30mg …
Matched Mixtures name: … Pancold A ... Saridon - A ... A & C Tablets With Codeine 30mg …
Guanidine
A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is...
Approved
Matched Description: … It is also used in laboratory research as a protein denaturant. ... It is found in the urine as a normal product of protein metabolism. ... A strong organic base existing primarily as guanidium ions at physiological pH. …
Melatonin
Melatonin is a biogenic amine that is found in animals, plants and microbes. Aaron B. Lerner of Yale University is credited for naming the hormone and for defining its chemical structure in 1958. In mammals, melatonin is produced by the pineal gland. The pineal gland is small endocrine gland, about...
Approved
Nutraceutical
Vet approved
Matched Description: … The pineal gland is small endocrine gland, about the size of a rice grain and shaped like a pine cone ... Melatonin is a biogenic amine that is found in animals, plants and microbes. Aaron B. ... A 2008 study found that unaffected parents of individuals with ASD also have lower melatonin levels, …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Elbasvir
Elbasvir is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C, an infectious liver disease caused by infection with hepatitis C virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in...
Approved
Matched Description: … Elbasvir is a direct-acting antiviral medication used as part of combination therapy to treat chronic ... Elbasvir is an inhibitor of NS5A, a protein essential for viral replication and virion assembly. ... HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 …
Valoctocogene roxaparvovec
Valoctocogene roxaparvovec is an adeno-associated virus serotype 5 (AAV5) based gene therapy vector that expresses the B-domain deleted SQ form of human coagulation factor VIII (hFVIII-SQ). The expression of hFVIII-SQ is driven by a liver-specific promoter, which enables hepatocytes to produce factor VIII protein and increase the levels of active...
Approved
Investigational
Matched Description: … [L43282] The expression of hFVIII-SQ is driven by a liver-specific promoter, which enables hepatocytes ... [L43292] Hemophilia A treatments such as prophylactic regimens of exogenous factor VIII or [emicizumab ... roxaparvovec was approved by EMA in September 2022 and is indicated for the treatment of severe hemophilia A. …
CVac
Approved
Investigational
Displaying drugs 351 - 375 of 11465 in total