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Displaying drugs 76 - 100 of 14925 in total
Oteracil is an adjunct to antineoplastic therapy, used to reduce the toxic side effects associated with chemotherapy. Approved by the European Medicines Agency (EMA) in March 2011, Oteracil is available in combination with DB09257 and DB09256 within the commercially available product "Teysuno". The main active ingredient in Teysuno is DB09256,...
Approved
Matched Synonyms: … Oxonic Acid ... 5-azaorotic acid ... Allantoxanic acid
Matched Iupac: … 4,6-dioxo-1,4,5,6-tetrahydro-1,3,5-triazine-2-carboxylic acid
Matched Description: … European Medicines Agency (EMA) in March 2011, Oteracil is available in combination with [DB09257] and ... By mimicking a class of compounds called "pyrimidines" that are essential components of RNA and DNA, ... 5-FU is able to insert itself into strands of DNA and RNA, thereby halting the replication process necessary …
An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.
Approved
Matched Synonyms: … 3-phenoxyhydratropic acid ... (+/-)-m-phenoxyhydratropic acid ... 2-(3-phenoxyphenyl)propionic acid
Matched Iupac: … 2-(3-phenoxyphenyl)propanoic acid
Matched Description: … An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. …
Matched Categories: … Arylpropionic acid NSAIDS ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements. Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical formulations. The most recent...
Approved
Matched Synonyms: … Isodecenoic acid vanillylamide …
Matched Description: … Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, ... and patch preparations of various strengths; however, it may also be found in some dietary supplements …
Matched Mixtures name: … Satohap Cool and Hot Pads ... Zostrix Hot and Cold Therapy System ... Cajun Hot Ice Muscle and Joint Pain Rub …
Matched Categories: … Basic Lotions and Liniments ... Capsaicin and Similar Agents ... Topical Products for Joint and Muscular Pain …
Matched Products: … Sherman and Clark Pain Relieving ... CareALL Arthritis and Muscle ... beeRX Muscle and Joint Pain Relief …
Defibrotide is the sodium salt of a mixture of single-stranded oligodeoxyribonucleotides derived from porcine mucosal DNA. It has been shown to have antithrombotic, anti-inflammatory and anti-ischemic properties (but without associated significant systemic anticoagulant effects). It is marketed under the brand names Dasovas (FM), Noravid, and Prociclide in a variety of...
Approved
Investigational
Matched Synonyms: … Defibrotide free acid ... Defibrotide free acid (porcine) ... Defibrotide free acid (porcine mucosa) …
Matched Description: … It has been shown to have antithrombotic, anti-inflammatory and anti-ischemic properties (but without ... It is marketed under the brand names Dasovas (FM), Noravid, and Prociclide in a variety of countries. …
Matched Categories: … Blood and Blood Forming Organs ... Nucleic Acids, Nucleotides, and Nucleosides …
A sulfur containing essential amino acid that is important in many body functions. It is a chelating agent for heavy metals.
Approved
Nutraceutical
Matched Synonyms: … L-a-Amino-g-methylthiobutyric acid ... (S)-2-amino-4-(methylthio)butanoic acid ... (S)-2-amino-4-(methylthio)butyric acid
Matched Iupac: … (2S)-2-amino-4-(methylsulfanyl)butanoic acid
Matched Description: … A sulfur containing essential amino acid that is important in many body functions. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Men's Biomultiple Vitamin and Mineral Supplement …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis....
Approved
Investigational
Matched Synonyms: … 3-fluoro-4-phenylhydratropic acid ... 2-(2-fluorobiphenyl-4-yl)propanoic acid ... (±)-2-fluoro-α-methyl-4-biphenylacetic acid
Matched Iupac: … 2-{2-fluoro-[1,1'-biphenyl]-4-yl}propanoic acid
Matched Description: … Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic ... and analgesic activity. ... Flurbiprofen is structurally and pharmacologically related to fenoprofen, ibuprofen, and ketoprofen. …
Matched Categories: … Arylpropionic acid NSAIDS ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Strepsils MaxPro Honey and Lemon lozenges 8.75mg …
Difenoxin is a 4-phenylpiperidine which is closely related to the opioid analgesic meperidine. Difenoxin alone is a USA Schedule I controlled drug, as it may be habit forming. However, it is listed as a Schedule IV controlled drug if combined with atropine, which is added to decrease deliberate misuse. Motofen(R)...
Approved
Illicit
Matched Synonyms: … Diphenoxilic acid ... Diphenoxylic acid ... 1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotic acid
Matched Iupac: … 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid
Matched Description: … It is approved by the FDA to treat acute and chronic diarrhea. ... Motofen(R) is a brand mixture which combines atropine sulfate and difenoxin hydrochloride. ... It works mostly in the periphery and activates opioid receptors in the intestine rather than the central …
Matched Categories: … Alimentary Tract and Metabolism …
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor...
Approved
Investigational
Matched Synonyms: … Heparinic acid
Matched Description: … coagulation enzymes thrombin (factor IIa) and factor Xa. ... UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. ... It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates …
Matched Mixtures name: … Heparin Sod and 0.9% Sod Chloride Inj ... Heparin Sodium and Dextrose 5% Inj USP …
Matched Categories: … Heparin and similars ... Blood and Blood Forming Organs …
Matched Products: … Heparin Sodium and Dextrose ... Heparin Sodium and Sodium Chloride …
A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Approved
Matched Synonyms: … Phenylbutyric acid nitrogen mustard ... 4-(p-bis(beta-chloroethyl)aminophenyl)butyric acid ... 4-(p-bis(β-chloroethyl)aminophenyl)butyric acid
Matched Iupac: … 4-{4-[bis(2-chloroethyl)amino]phenyl}butanoic acid
Matched Description: … nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Taurine, whose chemical name is 2-aminoethanesulfonic acid, is one of the most abundant amino acids in several organs. It plays important role in essential biological processes. This conditional amino acid can be either be manufactured by the body or obtained in the diet mainly by the consumption of fish and...
Approved
Nutraceutical
Matched Synonyms: … Aminoethylsulfonic acid
Matched Iupac: … 2-aminoethane-1-sulfonic acid
Matched Description: … mainly by the consumption of fish and meat. ... Taurine, whose chemical name is 2-aminoethanesulfonic acid, is one of the most abundant amino acids in ... [A31396] This conditional amino acid can be either be manufactured by the body or obtained in the diet …
Matched Mixtures name: … Premasol - sulfite-free (Amino Acid) ... Premasol - sulfite-free (Amino Acid) ... PRIMENE 10% AMINO ACID INTRAVENOUS INFUSION …
Matched Categories: … Amino Acids, Peptides, and Proteins …
An amino acid derivative that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as creatinine in the urine.
Approved
Investigational
Nutraceutical
Matched Synonyms: … (α-methylguanido)acetic acid ... (alpha-Methylguanido)acetic acid ... alpha-Methylguanidino acetic acid
Matched Iupac: … 2-(N-methylcarbamimidamido)acetic acid
Matched Description: … An amino acid derivative that occurs in vertebrate tissues and in urine. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
A depressor amine derived by enzymatic decarboxylation of histidine. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
Approved
Investigational
Matched Description: … a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and
Matched Mixtures name: … Histamine DHCl 0.10 Percent and Menthol 2 Percent …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Bakers Best Arthritis Pain Relief with Hemp Seed ... Hand and Wrist Pain Cream ... Australian Dream Hand and Wrist Pain …
Diflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic actions similar to other prototypical NSAIAs. Diflunisal possesses anti-inflammatory, analgesic and antipyretic activity. Though its mechanism of action has not been clearly established, most of its actions appear to be associated with inhibition of prostaglandin synthesis via the...
Approved
Investigational
Matched Synonyms: … 5-(2,4-difluorophenyl)salicylic acid ... 2-(hydroxy)-5-(2,4-difluorophenyl)benzoic acid ... 2',4'-difluoro-4-hydroxy-3-biphenylcarboxylic acid
Matched Iupac: … 2',4'-difluoro-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acid
Matched Description: … its actions appear to be associated with inhibition of prostaglandin synthesis via the arachidonic acid ... rheumatoid arthritis and osteoarthritis. ... Diflunisal possesses anti-inflammatory, analgesic and antipyretic activity. …
Matched Categories: … Salicylic Acid and Derivatives …
Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of acetaminophen overdose.[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.[A228158,A228163,A228168] Acetylcysteine was granted FDA approval on 14 September 1963.
Approved
Investigational
Matched Synonyms: … Mercapturic acid ... (R)-mercapturic acid ... (2R)-2-acetylamino-3-sulfanylpropanoic acid
Matched Iupac: … (2R)-2-acetamido-3-sulfanylpropanoic acid
Matched Description: … Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment …
Matched Mixtures name: … Levomefolate Calcium Acetylcysteine and Mecobalamin Algal ... Levomefolate Calcium, Acetylcysteine, Mecobalamin and Algal …
Matched Categories: … Cough and Cold Preparations ... Amino Acids, Peptides, and Proteins …
Potassium bicarbonate is a white, crystalline, slightly alkaline and salty substance. It is produced by the passage of carbon dioxide through an aqueous potassium carbonate solution. It is used in medicine as an antacid. It is registered in the FDA under the section of suitable, safe and effective ingredients for...
Approved
Matched Synonyms: … Carbonic acid, monopotassium salt …
Matched Description: … Potassium bicarbonate is a white, crystalline, slightly alkaline and salty substance. ... [T141] It is registered in the FDA under the section of suitable, safe and effective ingredients for …
Matched Mixtures name: … Isotonix Vitamin B-folic Acid-mineral Supple ... Coenzyme Q10 Isotonix Vitamin and Mineral Supplement ... Isotonix Advanced B-complex Vitamins With Potassium and Magnesium …
Matched Categories: … Carbonic Acid ... Alimentary Tract and Metabolism …
Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in concentrations up to 8%, as regulated by the FDA . It is a structurally-related compound to DB02362 that absorbs UV-B rays to prevent photodamage. It penetrates human skin, and is shown to induce non-ligatable strand...
Approved
Matched Description: … It penetrates human skin, and is shown to induce non-ligatable strand breaks on DNA _in vitro_ and mutagenic ... Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in …
Matched Mixtures name: … Sun and Ski Stick SPF 15 ... Aruba Aloe Lip Sunscreen and Moisturizer ... Phineas and Ferb Sun Smacker SPF 24 Berry Busted …
Matched Products: … Blue Green Algae With Grape Seed Extract Moisturizer SPF 10 ... Hand and Body Lotion SPF 15 ... Green Tea and Ginkgo Moisturizer SPF 10 …
Dexibuprofen, S(+)-ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID). It is a pharmacologically effective enantiomer of racemic ibuprofen that differs in physicochemical properties. It is proposed to be more pharmacologically active and tolerable with a better safety profile than ibuprofen due to higher concentration of active S enantiomer. Dexibuprofen has a...
Approved
Investigational
Matched Synonyms: … (+)-(S)-p-isobutylhydratropic acid ... (2S)-2-(4-isobutylphenyl)propanoic acid ... (S)-α-methyl-4-(2-methylpropyl)benzeneacetic acid
Matched Iupac: … (2S)-2-[4-(2-methylpropyl)phenyl]propanoic acid
Matched Description: … the racemic ibuprofen and displays improved oral bioavilability [A19259]. ... Dexibuprofen has a slower dissolution rate in the simulated gastric and enteric juices compared with ... It is proposed to be more pharmacologically active and tolerable with a better safety profile than ibuprofen …
Matched Categories: … Ibuprofen and isomer ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Ecamsule is an organic compound which is added to many sunscreens to filter out UVA rays. It is a benzylidene camphor derivative, many of which are known for their excellent photostability. Ecamsule has been approved for use in the U.S. since 2006, but only at a specific concentration and only...
Approved
Matched Synonyms: … Terephthalylidene dicamphor sulfonic acid
Matched Iupac: … heptan-2-ylidene]methyl}phenyl)methylidene]-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl}methanesulfonic acid
Matched Description: … Ecamsule has been approved for use in the U.S. since 2006, but only at a specific concentration and only …
Matched Mixtures name: … Kiehls Activated Sun Protector Sunscreen SPF 50 For Face and Body For All Skin Types ... Kiehls Activated Sun Protector Sunscreen SPF 30 For Face and Body For All Skin Types ... Kiehls Activated Sun Protector Ultra Light Sunscreen SPF 50 for Body Sweat and Water Resistant …
Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional NSAIDs in double-blind studies [A19667, A19668, A19670]. Aceclofenac potently inhibits the...
Approved
Investigational
Matched Synonyms: … 2-[(2,6-dichlorophenyl)amino]phenylacetoxyacetic acid ... 2-[(2',6'-dichlorophenyl)amino]phenylacetoxyacetic acid ... glycolic acid [o-(2,6-dichloroanilino)phenyl]acetate ester …
Matched Iupac: … 2-[(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetyl)oxy]acetic acid
Matched Description: … Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and ... analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. ... displays high permeability to penetrate into synovial joints where in patients with osteoarthritis and
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Cefoxitin is a semi-synthetic, broad-spectrum cepha antibiotic for intravenous administration. It is derived from cephamycin C, which is produced by Streptomyces lactamdurans.
Approved
Matched Synonyms: … methyl]-7-methoxy-8-oxo-7-[(thiophen-2-enyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Iupac: … methyl]-7-methoxy-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Products: … Cefoxitin and Dextrose …
Sulfasalazine is an anti-inflammatory drug structurally related to salicylates and other non-steroidal anti-inflammatory drugs. It is indicated for managing inflammatory diseases such as ulcerative colitis and rheumatoid arthritis (RA).[L39065, A255582] Metabolized by intestinal bacteria, sulfasalazine is broken down into mesalazine and sulfapyridine, 2 compounds that carry out the main pharmacological...
Approved
Matched Synonyms: … 5-(p-(2-Pyridylsulfamyl)phenylazo)salicylic acid ... 5-((p-(2-Pyridylsulfamoyl)phenyl)azo)salicylic acid ... 5-(4-(2-Pyridylsulfamoyl)phenylazo)-2-hydroxybenzoic acid
Matched Iupac: … 2-hydroxy-5-[(E)-2-{4-[(pyridin-2-yl)sulfamoyl]phenyl}diazen-1-yl]benzoic acid
Matched Description: … Sulfasalazine is an anti-inflammatory drug structurally related to salicylates and other non-steroidal ... It is indicated for managing inflammatory diseases such as ulcerative colitis and rheumatoid arthritis ... L39065, A255582] Metabolized by intestinal bacteria, sulfasalazine is broken down into [mesalazine] and
Matched Categories: … Alimentary Tract and Metabolism …
Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used by veterinarians as a supportive treatment for the relief of arthritic symptoms in geriatric dogs. Carprofen was previously used in human medicine for over 10 years (1985-1995). It was generally well tolerated, with the majority of adverse effects being mild,...
Approved
Vet approved
Withdrawn
Matched Synonyms: … (±)-6-chloro-α-methylcarbazole-2-acetic acid ... 2-(6-Chloro-9H-carbazol-2-yl)-propionic acid ... (+/-)-2-(3-chloro-9H-carbazol-7-yl)propanoic acid
Matched Iupac: … 2-(6-chloro-9H-carbazol-2-yl)propanoic acid
Matched Description: … nausea, similar to those recorded with aspirin and other non-steroidal anti-inflammatory drugs. ... generally well tolerated, with the majority of adverse effects being mild, such as gastro-intestinal pain and
Sodium Carbonate is the disodium salt of carbonic acid with alkalinizing property. When dissolved in water, sodium carbonate forms carbonic acid and sodium hydroxide. As a strong base, sodium hydroxide neutralizes gastric acid thereby acting as an antacid.
Approved
Matched Synonyms: … Carbonic acid, disodium salt ... Carbonic acid sodium salt (1:2) ... Sodium salt of carbonic acid
Matched Description: … When dissolved in water, sodium carbonate forms carbonic acid and sodium hydroxide. ... Sodium Carbonate is the disodium salt of carbonic acid with alkalinizing property. ... As a strong base, sodium hydroxide neutralizes gastric acid thereby acting as an antacid. …
Matched Categories: … Carbonic Acid
A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Meprobamate has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated)....
Approved
Illicit
Matched Synonyms: … Meprobamic acid
Matched Description: … A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses ... It is used in the treatment of anxiety disorders, and also for the short-term management of insomnia …
Matched Categories: … Hypnotics and Sedatives …
Potassium perchlorate is an inorganic salt with the chemical formula KClO4. It is a strong oxidizer with the lowest solubility of the alkali metal perchlorates. Potassium is most commonly used in flares and automobile airbags . The use of potassium perchlorate as a component in sealing gaskets for food containers...
Approved
Investigational
Matched Synonyms: … Perchloric acid, potassium salt …
Matched Description: … Potassium is most commonly used in flares and automobile airbags [A32609]. ... perchlorate in thyroid disorders has been ceased due to a high risk for developing aplastic anemia and ... Potassium perchlorate acts as a competitive inhibitor of iodine uptake by the thyroid gland and attenuates …
Matched Categories: … Sex Hormones and Insulins …
Displaying drugs 76 - 100 of 14925 in total