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Displaying drugs 151 - 175 of 654 in total
Sulfathiazole is a short-acting sulfa drug. It used to be a common oral and topical antimicrobial until less toxic alternatives were discovered. It is still occasionally used, sometimes in combination with sulfabenzamide and sulfacetamide. Except for those formulated for vaginal use, the FDA withdrew its approval for the use of...
Approved
Vet approved
Withdrawn
Matched Description: … It used to be a common oral and topical antimicrobial until less toxic alternatives were discovered. ... It is still occasionally used, sometimes in combination with sulfabenzamide and sulfacetamide. …
Matched Salts name: … Sulfathiazole sodium
Matched Categories: … Sulfonamides and trimethoprim ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Approved
Withdrawn
Matched Iupac: … (2,2,2-trichloroethoxy)phosphonic acid
Matched Salts name: … Triclofos sodium
Matched Categories: … Hypnotics and Sedatives …
Dofetilide is a class III antiarrhythmic agent that is approved by the Food and Drug Administration (FDA) for the maintenance of sinus rhythm in individuals prone to the formation of atrial fibrillation and flutter, and for the chemical cardioversion to sinus rhythm from atrial fibrillation and flutter.
Approved
Investigational
Matched Description: … flutter, and for the chemical cardioversion to sinus rhythm from atrial fibrillation and flutter. ... Dofetilide is a class III antiarrhythmic agent that is approved by the Food and Drug Administration ( ... FDA) for the maintenance of sinus rhythm in individuals prone to the formation of atrial fibrillation and
Torasemide is a high-ceiling loop diuretic. Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. Torasemide was first approved for clinical use by the FDA in 1993.
Approved
Matched Categories: … Sodium Potassium Chloride Symporter Inhibitors …
Eplerenone, an aldosterone receptor antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of the negative regulatory feedback of aldosterone on renin secretion. The resulting increased plasma renin activity and aldosterone circulating levels do not overcome the effects of...
Approved
Matched Description: … antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and ... The resulting increased plasma renin activity and aldosterone circulating levels do not overcome the ... mineralocorticoid receptors relative to its binding to recombinant human glucocorticoid, progesterone and
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Tezacaftor is a drug of the cystic fibrosis transmembrane conductance regulator (CFTR) potentiator class. It was developed by Vertex Pharmaceuticals and FDA approved in combination with ivacaftor to manage cystic fibrosis. This drug was approved by the FDA on February 12, 2018. Cystic Fibrosis is an autosomal recessive disorder caused...
Approved
Investigational
Matched Description: … sodium ions across cell membranes. ... consequently abnormal fluid and ion transport across cell membranes. ... [L1595] It was developed by Vertex Pharmaceuticals and FDA approved in combination with [ivacaftor] to …
Matched Categories: … ivacaftor and tezacaftor ... ivacaftor, tezacaftor and elexacaftor …
Sitaxentan was marketed under the trade name Thelin for the treatment of pulmonary arterial hypertension (PAH) by Encysive Pharmaceuticals until Pfizer purchased Encysive in February 2008. In 2010, Pfizer voluntarily removed sitaxentan from the market over concerns of hepatotoxicity.
Approved
Investigational
Withdrawn
Matched Salts name: … Sitaxentan sodium
Givosiran is a small interfering RNA (siRNA) directed towards 5-aminolevulinic acid synthase, a critical enzyme in the heme biosynthesis pathway. It is manufactured by Alnylam Pharmaceuticals and was first approved for use in the United States in November 2019 for the treatment of adults with acute hepatic porphyria, a genetic...
Approved
Investigational
Matched Description: … Givosiran is a small interfering RNA (siRNA) directed towards 5-aminolevulinic acid synthase, a critical ... [L10202] It is manufactured by Alnylam Pharmaceuticals and was first approved for use in the United States ... genetic disorder in which the overproduction of toxic heme intermediates leads to neuro-, nephro-, and
Matched Salts name: … Givosiran sodium
Matched Categories: … Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products …
Lifitegrast is a FDA approved drug for the treatment of keratoconjunctivitis sicca (dry eye syndrome). It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist that was discovered through the rational design process. The ophthalmic solution was approved in July, 2016 under the trade name Xiidra. It has...
Approved
Matched Iupac: … carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinolin-6-yl]formamido}-3-(3-methanesulfonylphenyl)propanoic acid
Matched Description: … onset of action and well tolerated profile in both local and systemic setting [A18805]. ... It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist ... It has shown to protect the corneal surface and alleviate the symptoms of dry eye syndrome with fast …
Matched Salts name: … Lifitegrast sodium
Matched Categories: … Amino Acids, Peptides, and Proteins …
Temocillin has been investigated in Infection, Liver Dysfunction, and Urinary Tract Infection.
Approved
Investigational
Matched Iupac: … thiophen-3-yl)acetamido]-6-methoxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Matched Description: … Temocillin has been investigated in Infection, Liver Dysfunction, and Urinary Tract Infection. …
Matched Salts name: … Temocillin Sodium
Bictegravir is a recently approved investigational drug that has been used in trials studying the treatment of HIV-1 and HIV-2 infection. It has been approved for HIV-1 monotherapy combined with 2 other antiretrovirals in a single tablet.
Approved
Investigational
Matched Description: … recently approved investigational drug that has been used in trials studying the treatment of HIV-1 and
Matched Salts name: … Bictegravir sodium
Matched Categories: … emtricitabine, tenofovir alafenamide and bictegravir …
Cardioactive derivative of lanatoside A or of digitoxin used for fast digitalization in congestive heart failure.
Approved
Tolbutamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It is structurally similar to acetohexamide, chlorpropamide and tolazamide and belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin...
Approved
Investigational
Matched Description: … Tolbutamide and its metabolites are excreted in urine (75-85%) and feces. ... It is structurally similar to acetohexamide, chlorpropamide and tolazamide and belongs to the sulfonylurea ... increase the number and sensitivity of insulin receptors. …
Matched Salts name: … Tolbutamide sodium
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).[label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate into ions which was believed to reduce GI toxicity by limiting local action. While slightly reduced, possibly due to a degree...
Approved
Matched Description: … Nabumetone was developed by Smithkline Beecham under the trade name Relafen and first received FDA approval ... [label,A178903] The molecule itself is a pro-drug with its 6-methoxy-2-naphthylacetic acid (6-MNA) metabolite …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Levetiracetam is a drug within the pyrrolidine class that is used to treat various types of seizures stemming from epileptic disorders. It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs).[L8606,L8600,L8615] Levetiracetam possesses a wide therapeutic index[L8615,A185918]...
Approved
Matched Description: … It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated ... [L8606,L8600,L8615] Levetiracetam possesses a wide therapeutic index[L8615,A185918] and little-to-no ... choice over other AEDs, a class of drugs notorious for having generally narrow therapeutic indexes and
Matched Products: … Levetiracetam in Sodium Chloride …
Approved
Matched Synonyms: … Phosphoric acid, sodium salt (1:2) ... Phosphoric acid, disodium salt, anhydrous ... Dibasic sodium phosphate anhydrous
Matched Name: … Sodium phosphate, dibasic …
Matched Mixtures name: … Monobasic Sodium Phosphate and Dibasic Sodium Phosphate ... Monobasic Sodium Phosphate and Dibasic Sodium Phosphate ... Dibasic Sodium Phosphate, Monobasic Potassium Phosphate and Monobasic Sodium Phosphate …
Matched Salts name: … Sodium phosphate, dibasic dihydrate ... Sodium phosphate, dibasic dodecahydrate ... Sodium phosphate, dibasic, heptahydrate ... Sodium phosphate, dibasic, monohydrate …
Approved
Experimental
Matched Synonyms: … Sodium molybdate (anhydrous) ... Sodium molybdate(VI) ... Molybdenum (as sodium) …
Matched Name: … Sodium molybdate …
Matched Mixtures name: … Multiple Vitamins and Minerals ... Prenatal Vitamin and Mineral Supplement ... Multivitamins and Minerals Tablets …
Matched Salts name: … Sodium molybdate dihydrate …
Sodium glycerophosphate is one of several glycerophosphate salts. It is used clinically to treat or prevent low phosphate levels [FDA Label]. Glycerophosphate is hydrolyzed to inorganic phosphate and glycerol in the body . The extent of this reaction is dependent on the activity of serum alkaline phosphatases.
Approved
Matched Synonyms: … Sodium glycerophosphate anhydrous
Matched Name: … Sodium glycerophosphate …
Matched Description: … Sodium glycerophosphate is one of several glycerophosphate salts. ... Glycerophosphate is hydrolyzed to inorganic phosphate and glycerol in the body [A32667]. …
Matched Mixtures name: … Vitamin and Mineral Supplement - Liq ... Hemarexin Liquid and Drinkable Ampoules …
Matched Salts name: … Sodium glycerophosphate hydrate …
Matched Categories: … sodium glycerophosphate ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Approved
Matched Synonyms: … Sodium acid carbonate ... Carbonic acid monosodium salt ... Sodium bicarbonate …
Matched Name: … Sodium bicarbonate …
Matched Iupac: … sodium hydrogen carbonate …
Matched Description: … replenisher, systemic alkalizer and in topical cleansing solutions. ... Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte …
Matched Mixtures name: … Omeprazole and Sodium Bicarbonate ... Omeprazole and Sodium Bicarbonate ... Omeprazole and Sodium Bicarbonate …
Matched Categories: … Carbonic Acid ... Gastric Acid Lowering Agents ... Sodium Compounds ... Antacids and Adsorbents ... sodium bicarbonate …
Matched Products: … Arm and Hammer Baking Soda ... Sodium Bicarbonate ... Sodium Bicarbonate 5 gr …
Approved
Experimental
Matched Synonyms: … Vanadic acid, monosodium salt ... Sodium vanadate ... Sodium vanadate(V) …
Matched Name: … Sodium metavanadate …
Matched Iupac: … sodium vanadiumoylolate …
Matched Mixtures name: … Multivitamins and Minerals Tablets ... Milltrium Senior Vitamin and Mineral Supplement ... Spectrum Performa Multivitamins and Minerals Tablets …
Matched Salts name: … Sodium metavanadate tetrahydrate …
Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores of lead from the body. It is on the World Health Organization Model List of Essential Medicines. Edetate calcium disodium was granted FDA approval on 16 July 1953.
Approved
Matched Synonyms: … Edetic acid calcium disodium salt ... Edetate calcium disodium (anhydrous) …
Matched Name: … Edetate calcium disodium anhydrous
Matched Description: … Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores …
Matched Categories: … Diet, Food, and Nutrition …
Matched Products: … Calcium Edetate de Sodium
Iron deficiency anemia is a large public health concern worldwide, especially in young children, infants, and women of childbearing age. This type of anemia occurs when iron intake, iron stores, and iron loss do not adequately support the formation of erythrocytes, also known as red blood cells. Ferrous sulfate is...
Approved
Matched Synonyms: … iron(2+) sulfate (anhydrous) …
Matched Name: … Ferrous sulfate anhydrous
Matched Description: … deficiency anemia is a large public health concern worldwide, especially in young children, infants, and ... It is the gold standard of oral iron therapy in the UK and many other countries.[L2234,L2246] ... [A190804] This type of anemia occurs when iron intake, iron stores, and iron loss do not adequately support …
Matched Mixtures name: … Exact-Rx SODIUM SULFACETAMIDE and SULFER 10%/5% Cleanser ... Tri-Vitamin with iron and fluoride ... Multi-Vit with Fluoride and Iron …
Sodium oxybate (Xyrem) is a central nervous system (CNS) depressant used to treat cataplexy or excessive daytime sleepiness associated with narcolepsy. It is a sodium salt of gamma-Hydroxybutyric acid, an endogenous cerebral inhibitory neurotransmitter and a metabolite of the inhibitory neurotransmitter GABA. Due to its physiological effects, sodium oxybate is...
Approved
Matched Synonyms: … Oxybate sodium ... Sodium oxybate …
Matched Name: … Sodium oxybate …
Matched Iupac: … sodium 4-hydroxybutanoate …
Matched Description: … [L30598] It is a sodium salt of [gamma-Hydroxybutyric acid], an endogenous cerebral inhibitory neurotransmitter ... Sodium oxybate has been misused to stimulate body growth and to induce euphoria, disinhibition, and sexual ... [L46302] In some countries, sodium oxybate has been investigated and used in alcohol withdrawal syndrome …
Matched Categories: … sodium oxybate ... sodium oxybate …
Matched Products: … Sodium Oxybate …
Sodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications, including dental care and radiographic imaging when it is used as Fluoride ion F-18. Sodium fluoride's benefits on dental health were first observed in the 1930s, when individuals in communities with fluoridated...
Approved
Matched Synonyms: … Sodium fluoride …
Matched Name: … Sodium fluoride …
Matched Iupac: … sodium fluoride …
Matched Description: … Now, sodium fluoride may be found in a variety of gels, varnishes, rinses, toothpaste products, and fluoride ... Sodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications ... [L4894] Sodium fluoride's benefits on dental health were first observed in the 1930s, when individuals …
Matched Mixtures name: … Sodium Fluoride and Vitamin D Drops ... Sodium Fluoride and Potassium Nitrate ... Sodium Fluoride 5000 ppm Sensitive …
Matched Categories: … Mouthwashes and Gargles ... Alimentary Tract and Metabolism ... sodium fluoride ... sodium fluoride ... Sodium Compounds …
Matched Products: … Amino Acid Fragrancemouthwash Dawn ... Amino Acid Fragrancemouthwash Blossom ... Truly Radiant Whitening and Strengthening Rinse CLEAN AND FRESH …
Sodium hydroxide is also known as lye or soda , or caustic soda . At room temperature, sodium hydroxide is a white crystalline odorless solid that absorbs moisture from the air. It is a synthetically manufactured substance. When dissolved in water or neutralized with acid it releases substantial amounts of...
Approved
Matched Synonyms: … sodium hydrate ... Sodium hydroxide …
Matched Name: … Sodium hydroxide …
Matched Iupac: … sodium hydroxide …
Matched Description: … When dissolved in water or neutralized with acid it releases substantial amounts of heat, which may prove ... in mad cow disease and kuru). ... It is also used in processing cotton fabric, laundering and bleaching, metal cleaning and processing, …
Matched Mixtures name: … COMPOUND SODIUM LACTATE INTRAVENOUS INFUSION BP …
Matched Categories: … Sodium Compounds …
Matched Products: … Sodium Hydroxide …
Displaying drugs 151 - 175 of 654 in total