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Displaying drugs 251 - 275 of 10408 in total

Trimipramine

Tricyclic antidepressant similar to imipramine, but with more antihistaminic and sedative properties.
Approved
Matched Categories: … Antidepressive Agents ... Antidepressive Agents, Tricyclic ... Antidepressive Agents Indicated for Depression ... Adrenergic Agents ... Serotonin Agents …

Tubocurarine

Tubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid. Curare is one of the names used to describe plant-derived poisons used by indigenous South Americans to coat the tips of hunting arrows and darts, which were typically derived from plants of the genera Chondrodendron and Strychnos....
Approved
Matched Categories: … Cholinergic Agents ... Anticholinergic Agents ... Neurotoxic agents ... Neuromuscular Agents ... Neurotransmitter Agents …

Piperaquine

Piperaquine is an antimalarial agent first synthesized in the 1960's and used throughout China . Its use declined in the 1980's as piperaquine resistant strains of Plasmodium falciparum appeared and artemisinin derivatives became available. It has come back into use in combination with the artemisinin derivative DB11638 as part of...
Approved
Experimental
Investigational
Matched Description: … Piperaquine is an antimalarial agent first synthesized in the 1960's and used throughout China [A31550 …
Matched Categories: … Anti-Infective Agents ... Antiparasitic Agents …

Lorazepam

Lorazepam is a short-acting and rapidly cleared benzodiazepine used commonly as a sedative and anxiolytic. It was developed by DJ Richards, presented and marketed initially by Wyeth Pharmaceuticals in the USA in 1977. The first historic FDA label approval is reported in 1985 by the company Mutual Pharm.
Approved
Matched Categories: … GABA Agents ... Autonomic Agents ... Anti-Anxiety Agents ... Tranquilizing Agents ... Gastrointestinal Agents …

Zalcitabine

A dideoxynucleoside compound in which the 3'-hydroxyl group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of 5' to 3' phosphodiester linkages, which are needed for the elongation of DNA chains, thus resulting in the termination of viral DNA growth. The compound is...
Approved
Investigational
Matched Description: … A dideoxynucleoside compound in which the 3'-hydroxyl group on the sugar moiety has been replaced by …
Matched Categories: … Anti-HIV Agents ... Antiviral Agents ... Anti-Infective Agents ... Anti-Retroviral Agents …

Patent Blue

Patent blue is aniline dye and it is one of the most common dyes used. It is a sodium or calcium salt of diethylammonium hydroxide inner salt. It has the chemical designation of (4-(alpha-(p-(diethylamino)phenyl)-2,4-disulfobenzylidene)-2,5-cyclohexadiene-1-ylidene)diethylammonium hydroxide. Patent blue was developed by Guerbet and approved by Health Canada on December 31, 1979....
Approved
Matched Description: … Patent blue was developed by Guerbet and approved by Health Canada on December 31, 1979. …
Matched Categories: … Coloring Agents ... Diagnostic Agents …

Ascorbic acid

A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic...
Approved
Nutraceutical
Matched Description: … Vitamin C is considered an antioxidant. ... Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and …
Matched Mixtures name: … Kanga-B Vitamin B Group + C …
Matched Categories: … Protective Agents ... Urinary Acidifying Agents ... Gastrointestinal Acidifying Agents …

Tazobactam

Tazobactam is an antibiotic of the beta-lactamase inhibitor class that prevents the breakdown of other antibiotics by beta-lactamase enzyme producing organisms. It is combined with Piperacillin and Ceftolozane for the treatment of a variety of bacterial infections. Piperacillin-tazobactam was initially approved by the FDA in 1994, and ceftolozane-tazobactam was approved...
Approved
Matched Description: … Tazobactam is an antibiotic of the beta-lactamase inhibitor class that prevents the breakdown of other ... Piperacillin-tazobactam was initially approved by the FDA in 1994, and ceftolozane-tazobactam was approved ... In June 2019, ceftolozane-tazobactam was approved by the FDA for treating hospital-acquired bacterial …
Matched Categories: … Anti-Infective Agents …

Wormwood

Wormwood is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … It is not an approved drug. …

Purslane

Purslane is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … It is not an approved drug. …

Chamomile

Chamomile is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Investigational
Matched Description: … It is not an approved drug. …

Sodium citrate

Sodium citrate is the sodium salt of citric acid. It is white, crystalline powder or white, granular crystals, slightly deliquescent in moist air, freely soluble in water, practically insoluble in alcohol. Like citric acid, it has a sour taste. From the medical point of view, it is used as alkalinizing...
Approved
Investigational
Matched Categories: … Neurotoxic agents ... Hematologic Agents …

Regorafenib

Regorafenib is an orally-administered inhibitor of multiple kinases. It is used for the treatment of metastatic colorectal cancer, advanced gastrointestinal stromal tumours, and hepatocellular carcinoma. FDA approved on September 27, 2012. Approved use of Regorafenib was expanded to treat Hepatocellular Carcinoma in April 2017.
Approved
Matched Description: … Regorafenib is an orally-administered inhibitor of multiple kinases. ... FDA approved on September 27, 2012. ... Approved use of Regorafenib was expanded to treat Hepatocellular Carcinoma in April 2017. …
Matched Categories: … Antineoplastic Agents ... Hepatotoxic Agents ... Bradycardia-Causing Agents ... Antineoplastic and Immunomodulating Agents …

Estradiol benzoate

Estradiol Benzoate is a pro-drug ester of DB00783, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex hormone. As a pro-drug of estradiol, estradiol benzoate therefore has the same downstream...
Approved
Investigational
Vet approved
Matched Description: … [DB00783] is commonly produced with an ester side-chain as endogenous estradiol has very low oral bioavailability …
Matched Categories: … Contraceptive Agents, Hormonal ... Reproductive Control Agents …

Antithymocyte immunoglobulin (rabbit)

Rabbit anti-thymocyte globulin. Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients. Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of...
Approved
Matched Categories: … Immunosuppressive Agents ... Miscellaneous Therapeutic Agents ... Antineoplastic and Immunomodulating Agents …

Amikacin

Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A.[FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A. Amikacin's unique property is that it exerts activity against more resistant gram-negative bacilli such as...
Approved
Investigational
Vet approved
Matched Description: … Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group ... [F1949] In September 2018, a liposomal inhalation suspension of this drug was approved by the FDA for ... [L4680] Several forms of amikacin are used currently, including an intravenous (IV) or intramuscular …
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents ... Nephrotoxic agents …

Milk thistle

Milk thistle is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Investigational
Matched Description: … It is not an approved drug. …

Epicriptine

Epicriptine is also known as beta-dihydroergocryptine presents a molecular formula of 9,10 alpha-dihydro-13'-epi-b-ergocryptine. Together with the alpha-dihydroergocryptine, it represents one-third of the ergoloid mesylate mixture. Epicriptine differs from the alpha form on the position of one methyl group. To know more about the mixture please visit DB01049
Approved
Matched Description: … Epicriptine differs from the alpha form on the position of one methyl group. …

Calendula officinalis flower

Calendula officinalis flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … It is not an approved drug. …

Corydalis ambigua tuber

Corydalis ambigua tuber is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … It is not an approved drug. …

Lonicera caprifolium flower

Lonicera caprifolium flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … It is not an approved drug. …

Azadirachta indica leaf

Azadirachta indica leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … It is not an approved drug. …

Cashew fruit

Cashew fruit extract is used in allergenic testing.
Approved

Enalaprilat

Enalaprilat is the active metabolite of the orally available pro-drug, enalapril. Used in the treatment of hypertension, enalapril is an ACE inhibitor that prevents Angiotensin Converting Enzyme (ACE) from transforming angiotensin I into angiotensin II. As angiotensin II is responsible for vasoconstriction and sodium reabsorption in the proximal tubule of...
Approved
Matched Description: … Removal of the problematic thiol group from captopril resulted in enalaprilat, which was then modified ... further with an ester to create the orally available pro-drug enalapril. ... Used in the treatment of hypertension, enalapril is an ACE inhibitor that prevents Angiotensin Converting …
Matched Categories: … Hypotensive Agents ... Agents causing angioedema ... Cardiovascular Agents ... Antihypertensive Agents ... Agents causing hyperkalemia …

Desipramine

Desipramine hydrochloride is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, desipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, desipramine exerts a positive...
Approved
Investigational
Matched Description: … They contain a tricyclic ring system with an alkyl amine substituent on the central ring. ... The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission …
Matched Categories: … Antidepressive Agents ... Antidepressive Agents, Tricyclic ... Antidepressive Agents Indicated for Depression ... Adrenergic Agents ... Anticholinergic Agents …
Displaying drugs 251 - 275 of 10408 in total