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Displaying drugs 2776 - 2800 of 9733 in total

AstraZeneca COVID-19 Vaccine

The AstraZeneca COVID-19 Vaccine (previously known as ChAdOx1 nCoV-19 or AZD1222) is one of several vaccines developed in 2020 for the prevention of COVID-19 caused by SARS-CoV-2.[L12669,L32649] The ChAdOx1 viral vector was developed at the University of Oxford and has been investigated as a potential vector for vaccines against another...
Approved
Investigational
Matched Description: … 18 and 55. ... adenovirus capable of producing the spike (S) protein of SARS-CoV-2, allowing for the formation of endogenous ... COVID-19 Vaccine due to signals of an increased risk of blood clots associated with thrombocytopenia …

Aurothioglucose

Aurothioglucose, also known as gold thioglucose, was formerly used to treat rheumatoid arthritis. Contemporary research on the effect of gold salts treatment began in 1935, primarily to reduce inflammation and to slow disease progression in patients with rheumatoid arthritis . The use of gold compounds has decreased since the 1980s...
Approved
Withdrawn
Matched Description: … , and slow onset of action. ... Contemporary research on the effect of gold salts treatment began in 1935, primarily to reduce inflammation ... The use of gold compounds has decreased since the 1980s owing to numerous side effects, limited efficacy …

Obinutuzumab

Obinutuzumab is a humanized monoclonal antibody used as a combination treatment with chlorambucil to treat patients with untreated chronic lymphocytic leukemia. It was approved by the FDA in November 2013 and is marketed under the brand name Gazyva. There is a black box warning of fatal Hepatitis B Virus (HBV)...
Approved
Investigational
Matched Description: … There is a black box warning of fatal Hepatitis B Virus (HBV) reactivation and fatal Progressive Multifocal …
Matched Categories: … CD20 (Clusters of Differentiation 20) inhibitors …

Ioxilan

Ioxilan is a tri-iodinated diagnostic contrast agent. Intravascular injection results in opacification of vessels in the path of flow of the contrast medium, permitting radiographic visualization of the internal structures of the human body until significant hemodilution occurs.
Approved
Matched Description: … Intravascular injection results in opacification of vessels in the path of flow of the contrast medium ... , permitting radiographic visualization of the internal structures of the human body until significant …
Matched Categories: … Diagnostic Uses of Chemicals …

Nitroglycerin

Nitroglycerin, also known as glyceryl trinitrate, is an organic nitrate and a vasodilating agent that was first discovered in 1847. Originally used to dynamite, its antianginal effects were identified in the late 1860s after it produced headaches in factory workers while workers with angina pectoris or heart failure experienced relief...
Approved
Investigational
Matched Description: … [A180172] Nitroglycerin is used in a variety of different conditions, including angina pectoris due …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …

Gliclazide

Gliclazide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It has been classified differently according to its drug properties in which based on its chemical structure, gliclazide is considered a first-generation sulfonylurea due to the structural presence of a sulfonamide group able to release...
Approved
Matched Description: … Medications in this class differ in their dose, rate of absorption, duration of action, route of elimination ... the last 8-10 weeks of glucose control). ... β cells of the pancreas to release insulin. …
Matched Categories: … combinations of sulfonamides …

Loratadine

Loratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis. A lack of sedative and CNS adverse effects make loratadine, along with other second generation antihistamines, preferable over their 1st generation counterparts in many clinical situations.
Approved
Investigational
Matched Description: … Loratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis. ... [A176435] A lack of sedative and CNS adverse effects make loratadine, along with other second generation …
Matched Mixtures name: … LORAMINE R JARABE ... LORAMINE® R GRAGEAS ... DOSITAN (R) TABLETAS …
Matched Products: … LOTADAR(R) TABLETAS ... AIRET(R) TABLETAS 10 MG …

Desflurane

Desflurane, or I-653, a a volatile anesthetic that is more rapidly cleared and less metabolized than previous inhaled anesthetics such as methoxyflurane, sevoflurane, enflurane, or isoflurane.[A226390,A39015,A226893]. It was developed in the late 1980s out of a need for a more rapidly acting and rapidly cleared inhaled anesthetic.[A226883,A226888] Desflurane was granted...
Approved
Matched Description: … [A226883,A226888] Desflurane was granted FDA approval on 18 September 1992.[L30285] ... It was developed in the late 1980s out of a need for a more rapidly acting and rapidly cleared inhaled …

Mepivacaine

A local anesthetic that is chemically related to bupivacaine but pharmacologically related to lidocaine. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
Approved
Vet approved
Matched Products: … Polocaine(r) -mpf (mepivacaine Hci) …

Ranitidine

Ranitidine is a commonly used drug, classified as a histamine H2-receptor antagonist, and belongs to the same drug class as cimetidine and famotidine. This drug helps to prevent and treat gastric-acid associated conditions, including ulcers, because of its ability to decrease gastric acid secretion.[A176759,L10818] Ranitidine is often referred to as...
Approved
Withdrawn
Matched Description: … [L10818,F4253] The prevalence of GERD is thought to be 10-20% in western countries. ... This drug helps to prevent and treat gastric-acid associated conditions, including ulcers, because of ... [A176843] Ranitidine has proven to be an effective treatment for relieving uncomfortable symptoms of …
Matched Products: … NEOCEPTIN R-150 TABLET 150 mg …

Propranolol

Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors. Propranolol is used to treat a number of conditions but most commonly is used for hypertension.[L6901,L6904,L6907] Propranolol was granted FDA approval on 13 November 1967.
Approved
Investigational
Matched Description: … Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times ... [L6904] Propranolol is used to treat a number of conditions but most commonly is used for hypertension …

Dextromethorphan

Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse. Although similar in structure to other opioids, it has minimal interaction with opioid receptors. Dextromethorphan was granted FDA approval before 3 December 1957.[A215412,L14997]
Approved
Matched Description: … is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of …
Matched Mixtures name: … Regular Strength Cold Medication(daytime R.) ... Hot Lemon Relief for Symptoms Of Cough and Cold ... Hot Liquid Relief for Symptoms Of Cold and Cough …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Dicloxacillin

One of the penicillins which is resistant to penicillinase.
Approved
Investigational
Vet approved
Matched Description: … One of the penicillins which is resistant to penicillinase. …
Matched Categories: … combinations of penicillins …

Cyclopenthiazide

Cyclopenthiazide is a thiazide diuretic with antihypertensive properties. In a double blind, randomized crossover study, cyclopenthiazide was effective in reducing diastolic blood pressure in mildly hypertensive non-insulin dependent diabetic patients . It is a positive allosteric modulator at AMPA-A receptors .
Approved
Matched Categories: … combinations of sulfonamides …

Risdiplam

Risdiplam is an orally bioavailable mRNA splicing modifier used for the treatment of spinal muscular atrophy (SMA). It increases systemic SMN protein concentrations by improving the efficiency of SMN2 gene transcription. This mechanism of action is similar to its predecessor nusinersen, the biggest difference being their route of administration: nusinersen...
Approved
Investigational
Matched Description: … [onasemnogene abeparvovec], whereas risdiplam offers the ease of oral bioavailability. ... Risdiplam is an orally bioavailable mRNA splicing modifier used for the treatment of spinal muscular ... [L12615] It increases systemic SMN protein concentrations by improving the efficiency of _SMN2_ gene …
Matched Categories: … Survival of Motor Neuron 2 Splicing Modifier …

Tolevamer

Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels. It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among others, HIV.
Approved
Investigational
Matched Description: … It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …

Raltegravir

Raltegravir is an antiretroviral drug produced by Merck & Co., used to treat HIV infection. It received approval by the U.S. Food and Drug Administration (FDA) on 12 October 2007, the first of a new class of HIV drugs, the integrase inhibitors, to receive such approval.
Approved
Matched Description: … Food and Drug Administration (FDA) on 12 October 2007, the first of a new class of HIV drugs, the integrase …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections …

Risperidone

Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and mental health conditions including schizophrenia and bipolar disorder. It is one of the most widely used SGAs. Paliperidone, another commonly used SGA, is the primary active metabolite of risperidone (i.e. 9-hydroxyrisperidone). Schizophrenia and...
Approved
Investigational
Matched Description: … Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of ... [L12885] It is one of the most widely used SGAs. ... Risperidone is thought to reduce this overactivity through inhibition of dopaminergic D2 receptors and …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … ISPERIN(R)FAST 0.5 MG ... RISPERDAL CONSTA (R) 50 MG ... ISPERIN(R)FAST 2 MG TABLETA ORODISPERSABLE …

Davesomeran

Davesomeran is a mRNA vaccine used in conjunction with elasomeran as part of the Moderna Bivalent COVID-19 vaccine. Similar to the previous Moderna COVID-19 vaccine, Moderna Bivalent vaccine encodes the full-length pre-fusion stabilized spike (S) protein to elicit an immune response.[L43882,L28026] However, with the addition of davesomeran, Moderna Bivalent vaccine...
Approved
Investigational
Matched Description: … [L43882] A phase 2 and 3 open-label study in participants 18 years or older who had previously received ... 3rd 2022, Health Canada also approved the Moderna Bivalent Vaccine as a booster shot in individuals 18 ... years of age or older. …

Sparfloxacin

Sparfloxacin is a fluoroquinolone antibiotic indicated for bacterial infections. Sparfloxacin exerts its antibacterial activity by inhibiting DNA gyrase, a bacterial topoisomerase. DNA gyrase is an essential enzyme which controls DNA topology and assists in DNA replication, repair, deactivation, and transcription.
Approved
Investigational
Withdrawn
Matched Categories: … Drugs for Treatment of Tuberculosis …

Polythiazide

A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p826)
Approved
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. …
Matched Mixtures name: … Renese-R …
Matched Categories: … combinations of sulfonamides …

Insulin glargine

Insulin glargine is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched International brands: … Lantus R …
Matched Description: … , with a goal of avoiding any periods of hypoglycemia. ... Insulin glargine is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type ... B31 and 32) of the B-chain. …

Mebendazole

A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]
Approved
Vet approved
Matched Description: … A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of …
Matched Products: … MEBENDAL (R) TABLETAS …

Dopamine

One of the catecholamine neurotransmitters in the brain. It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (receptors, dopamine) mediate its action.
Approved
Matched Description: … One of the catecholamine neurotransmitters in the brain. ... A family of receptors (receptors, dopamine) mediate its action. ... Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating …
Matched Products: … CARDIOPAL(R) 200 MG …

Lotilaner

Lotilaner is an ectoparasiticide that is a member of the isoxazoline family of compounds. Lotilaner has largely been used for veterinary uses as an antiparasitic agent to treat flea and tick infestations in animals.[A260746, L47556] Lotilaner consists of two enantiomers: the S-enantiomer is active in vivo, while the R-enantiomer is...
Approved
Vet approved
Matched Description: … the R-enantiomer is reported to exhibit low biological activity. ... Lotilaner is an ectoparasiticide that is a member of the isoxazoline family of compounds. ... The active ingredient found in drug products of lotilaner is the S-enantiomer. …
Displaying drugs 2776 - 2800 of 9733 in total