Did you mean bitopertin of rp 493838 of r 168 of ビトペルチン?
Displaying drugs 2801 - 2825 of 9508 in total
Levonorgestrel
Levonorgestrel (LNG) is a synthetic progestogen similar to Progesterone used in contraception and hormone therapy.[A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an intrauterine device, commonly referred to as an IUD. Some of these devices...
Approved
Investigational
Matched Description: … Some of these devices are known as Jaydess, Kyleena, and Mirena. ... A subdermal implant of levonorgestrel that slowly releases the hormone over a long-term period is also ... [L7823] In addition to the above uses, levonorgestrel is used as a component of long-term combination …
Matched Mixtures name: … LILA(R) TABLETAS RECUBIERTAS …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Matched Mixtures name: … LILA(R) TABLETAS RECUBIERTAS …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Palonosetron
Palonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). It is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that appear more than 24 hours after the first...
Approved
Investigational
Matched Description: … appear more than 24 hours after the first dose of a course of chemotherapy and is the only drug of its ... and treatment of chemotherapy-induced nausea and vomiting (CINV). ... As of 2008, it is the most recent 5-HT3 antagonist to enter clinical use. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Granisetron
A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant for cancer chemotherapy patients.
Approved
Investigational
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Pergolide
Pergolide is a long-acting dopamine agonist approved in 1982 for the treatment of Parkinson’s Disease. It is an ergot derivative that acts on the dopamine D2 and D3, alpha2- and alpha1-adrenergic, and 5-hydroxytryptamine (5-HT) receptors. It was indicated as adjunct therapy with levodopa/carbidopa in the symptomatic treatment of parkinsonian syndrome....
Approved
Investigational
Vet approved
Withdrawn
Matched Description: … It was later found that pergolide increased the risk of cardiac valvulopathy. ... Pergolide is a long-acting dopamine agonist approved in 1982 for the treatment of Parkinson’s Disease ... It was indicated as adjunct therapy with levodopa/carbidopa in the symptomatic treatment of parkinsonian …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Fusidic acid
An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed) It acts by inhibiting translocation during protein synthesis. It is often used topically in creams and eyedrops but is available in systemic formulations including tablets and injections.
Approved
Investigational
Matched Description: … An antibiotic isolated from the fermentation broth of Fusidium coccineum. …
Matched Mixtures name: … FUCICORT(R) …
Matched Mixtures name: … FUCICORT(R) …
Ribociclib
Ribociclib is a selective cyclin-dependent kinase inhibitor, a class of drugs that help slow the progression of cancer by inhibiting two proteins called cyclin-dependent kinase 4 and 6 (CDK4/6). These proteins, when over-activated, can enable cancer cells to grow and divide too quickly. Targeting CDK4/6 with enhanced precision may play...
Approved
Investigational
Matched Description: … of cancer by inhibiting two proteins called cyclin-dependent kinase 4 and 6 (CDK4/6). ... Ribociclib is a selective cyclin-dependent kinase inhibitor, a class of drugs that help slow the progression …
Mesalazine
An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory drugs like acetylsalicylic acid, which is active in inflammatory bowel disease . Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stability as a pharmaceutical...
Approved
Matched Description: … issues regarding its lack of stability as a pharmaceutical agent [A174019]. ... treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of ... important research initiatives developed stable mesalazine formulations like the eudragit-S coating of …
Matched Products: … Salofalk (r) 5-asa Suppositories - 250mg ... Salofalk (r) 5-asa Enteric Coated Tab- 250mg …
Matched Products: … Salofalk (r) 5-asa Suppositories - 250mg ... Salofalk (r) 5-asa Enteric Coated Tab- 250mg …
Rimantadine
An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza.
Approved
Investigational
Matched Description: … An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza …
Omeprazole
Originally approved by the FDA in 1989, omeprazole is a proton-pump inhibitor, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid. This drug was the first clinical useful drug in its class,...
Approved
Investigational
Vet approved
Matched Description: … reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of ... drug was the first clinical useful drug in its class, and its approval was followed by the formulation of …
Matched Products: … PRAZOGAS(R) INFUSION ... มีพราซิด(R) 40 มก. ชนิดฉีด …
Matched Products: … PRAZOGAS(R) INFUSION ... มีพราซิด(R) 40 มก. ชนิดฉีด …
Gentian violet cation
A dye that is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties.
Approved
Matched Description: … A dye that is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties …
Ritlecitinib
Ritlecitinib (PF-06651600) is a highly selective inhibitor of Janus kinase 3 (JAK3) and the tyrosine kinase expressed in hepatocellular carcinoma (TEC) kinase family. In June 2023, it was approved by the FDA for the treatment of severe alopecia areata in adults and adolescents 12 years and older.[L47092,L47127] It was further...
Approved
Investigational
Matched Description: … of alopecia areata. ... [L48181] Ritlecitinib is administered orally and is the first member of its class. ... Ritlecitinib (PF-06651600) is a highly selective inhibitor of Janus kinase 3 (JAK3) and the tyrosine …
Conjugated estrogens
The conjugated estrogens are noncrystalline mixtures of purified female sex hormones obtained either by its isolation from the urine of pregnant mares or by synthetic generation from vegetal material. Both of these products are later conjugated to natrium sulfate by ester bonds in order to make them more water soluble.[L5605,...
Approved
Matched Description: … , 3% of equilenin sulfate, 5% of 17-alpha and 17-beta-dihydroequilenin sulfate, 2% of 17-alpha-estradiolsulfate ... and 3% of 17-beta-estradiolsulfate. ... represented by estrone sulfate followed by 25% of equilin sulfate, 15% of 17-alpha-dehydroequilenin sulfate …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Sulfadiazine
One of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.
Approved
Investigational
Vet approved
Matched Description: … One of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in …
Matched Categories: … combinations of sulfonamides …
Matched Categories: … combinations of sulfonamides …
Secobarbital
Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties. It is commonly known as quinalbarbitone in the United Kingdom.
Approved
Vet approved
Matched Categories: … combinations of barbiturates …
Estrone
Estrone, one of the major mammalian estrogens, is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone. It is produced in vivo from androstenedione or from testosterone via estradiol. It is produced primarily in the ovaries, placenta, and in peripheral tissues (especially adipose tissue) through conversion of adrostenedione....
Approved
Matched Description: … Estrone, one of the major mammalian estrogens, is an aromatized C18 steroid with a 3-hydroxyl group and ... in the ovaries, placenta, and in peripheral tissues (especially adipose tissue) through conversion of …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Clofazimine
Clofazimine is a highly lipophilic antimicrobial riminophenazine dye used in combination with other agents, such as dapsone, for the treatment of leprosy. It was originally described in 1957 and was the prototypical riminophenazine dye - a bright-red dye that, in its clinical use, results in long-lasting discoloration of the skin...
Approved
Investigational
Matched Description: … antimicrobial riminophenazine dye used in combination with other agents, such as [dapsone], for the treatment of ... riminophenazine dye - a bright-red dye that, in its clinical use, results in long-lasting discoloration of …
Matched Categories: … Drugs for Treatment of Lepra …
Matched Categories: … Drugs for Treatment of Lepra …
Cyproterone acetate
An anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.
Approved
Investigational
Matched Description: … in combination with estrogen, for the therapy of severe acne and hirsutism in females. ... An anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties ... It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Grazoprevir
Grazoprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Matched Description: … alter the affinity of the drug for NS3/4A or the activity of the enzyme itself. ... another class of DAAs [A19593]. ... The barrier for develoment of resistance to NS3/4A inhibitors is lower than that of NS5B inhibitors, …
Matched Categories: … Antivirals for treatment of HCV infections …
Matched Categories: … Antivirals for treatment of HCV infections …
Velpatasvir
Velpatasvir is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Investigational
Matched Description: … ), after 12 weeks of daily therapy. ... reduced liver-related damage, improved quality of life, reduced incidence of Hepatocellular Carcinoma ... Epclusa is the first combination HCV product indicated for the treatment of all genotypes of Hepatitis …
Matched Categories: … Antivirals for treatment of HCV infections …
Matched Categories: … Antivirals for treatment of HCV infections …
Raltitrexed
Raltitrexed (brand name Tomudex®) is a chemotherapy drug manufactured AstraZeneca Company, is an antimetabolite used in chemotherapy. It is an inhibitor of thymidylate synthase.
Approved
Investigational
Matched Description: … It is an inhibitor of thymidylate synthase. …
Rapacuronium
Rapacuronium was withdrawn in 2001 in many countries due to risk of fatal bronchospasm.
Approved
Withdrawn
Matched Description: … Rapacuronium was withdrawn in 2001 in many countries due to risk of fatal bronchospasm. …
Pixantrone
Pixantrone is an aza-anthracenedione and DNA intercalator which inhibits topoisomerase II. It is similar in structure to anthracyclines such as mitoxantrone, but exerts fewer toxic effects on cardiac tissue. [2] The lower cardio-toxic effects of pixantrone may be explained, in part, by its redox inactivity [3]. Pixantrone does not bind...
Approved
Investigational
Matched Description: … Another phase III trial, PIX-R, is now ongoing to clarify pixantrones place in therapy. ... It will compare pixantrone efficacy to that of gemcitabine. [2] ... mitoxantrone, but exerts fewer toxic effects on cardiac tissue. [2] The lower cardio-toxic effects of …
Displaying drugs 2801 - 2825 of 9508 in total