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Displaying drugs 2801 - 2825 of 9573 in total
Rebamipide
Rebamipide has been investigated for the treatment of Stomach Ulcer, Keratoconjunctivitis Sicca, and Gastric Adenoma and Early Gastric Cancer.
Approved
Investigational
Matched Description: … Rebamipide has been investigated for the treatment of Stomach Ulcer, Keratoconjunctivitis Sicca, and …
Amylocaine
Despite the introduction of using cocaine injections for regional anesthesia in 1884, non-addictive substitutes were sought after immediately . Finally, in 1903 the world's first synthetic and non-addictive local anesthetic, amylocaine, was synthesized and patented under the name Forneaucaine by Ernest Fourneau at the Pasteur Institute . Elsewhere in English...
Approved
Withdrawn
Matched Description: … Despite the introduction of using cocaine injections for regional anesthesia in 1884, non-addictive substitutes ... Elsewhere in English speaking countries it was referred to as Stovaine, given the meaning of the French ... possessed less severe side effects than cocaine [L1882], the eventual development and clinical use of …
Metoprolol
Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release.[A175159, L5530] The possibility of the generation of these formulations comes from the lower systemic bioavailability of the succinate derivative. To this date,...
Approved
Investigational
Matched Description: … [A175159, L5530] The possibility of the generation of these formulations comes from the lower systemic ... bioavailability of the succinate derivative. ... commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of …
Matched Products: … LOPRESOR R ... CARDOXONE 200 R. ... Metoprolol Succinate E/r …
Matched Products: … LOPRESOR R ... CARDOXONE 200 R. ... Metoprolol Succinate E/r …
Gefitinib
Gefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer. Acting in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant proteins in malignant cells. It is marketed by AstraZeneca under the trade name Iressa.
Approved
Investigational
Matched Description: … Gefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer. …
Clove oil
Clove oil is obtained by extraction from the dried flower buds of the clove plant. Traditionally, it has been used as a flavouring spice in foods, or as a fragrance. It is also found in topical analgesics. Clove oil has shown to exert some antimicrobial activities. The antioxidant and antimicrobial...
Approved
Nutraceutical
Matched Description: … state of _Bahia_. ... The antioxidant and antimicrobial activity of clove is higher than that of many fruits, vegetables, and ... Clove is native of Indonesia but is now cultured in several parts of the world, including Brazil in the …
Aminolevulinic acid
A compound produced from succinyl-CoA and glycine as an intermediate in heme synthesis. It is used as a photochemotherapy for actinic keratosis. [PubChem]
Approved
Salicylic acid
A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics.
Approved
Investigational
Vet approved
Matched Description: … A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically …
Matched Products: … R-044 Blemish Fix ... Fruit of the Earth Acne Wash …
Matched Products: … R-044 Blemish Fix ... Fruit of the Earth Acne Wash …
Ranibizumab
Ranibizumab is a recombinant humanized IgG1 kappa isotype monoclonal antibody fragment directed against human vascular endothelial growth factor A (VEGF-A), which is a glycoprotein implicated in the pathophysiology of age-related macular degeneration.[A2301, L38978] Ranibizumab is used to treat various ocular disorders with abnormal growth of blood vessels, such as neovascular...
Approved
Matched Description: … only biosimilar drug of ranibizumab available in Canada. ... vascular endothelial growth factor A (VEGF-A), which is a glycoprotein implicated in the pathophysiology of ... The development of ranibizumab first began after [bevacizumab], another anti-VEGF anticancer drug, was …
Ramucirumab
Ramucirumab is a human monoclonal antibody (IgG1) against vascular endothelial growth factor receptor 2 (VEGFR2), a type II trans-membrane tyrosine kinase receptor expressed on endothelial cells. By binding to VEGFR2, ramucirumab prevents binding of its ligands (VEGF-A, VEGF-C, and VEGF-D), thereby preventing VEGF-stimulated receptor phosphorylation and downstream ligand-induced proliferation, permeability,...
Approved
Investigational
Matched Description: … By binding to VEGFR2, ramucirumab prevents binding of its ligands (VEGF-A, VEGF-C, and VEGF-D), thereby ... other agents directed against VEGFR-2, ramucirumab binds a specific epitope on the extracellular domain of ... VEGF-stimulated receptor phosphorylation and downstream ligand-induced proliferation, permeability, and migration of …
Rivaroxaban
Rivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. Unlike warfarin, routine lab monitoring of INR is not necessary. However there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15...
Approved
Matched Description: … Unlike warfarin, routine lab monitoring of INR is not necessary. ... However there is no antidote available in the event of a major bleed. …
Raxibacumab
Raxibacumab is a human IgG1λ monoclonal antibody that binds the protective antigen (PA) component of B. anthracis toxin. Raxibacumab has a molecular weight of approximately 146 kilodaltons. Raxibacumab is produced by recombinant DNA technology in a murine cell expression system. FDA approved on December 14, 2012.
Approved
Matched Description: … Raxibacumab has a molecular weight of approximately 146 kilodaltons. ... Raxibacumab is a human IgG1λ monoclonal antibody that binds the protective antigen (PA) component of …
Ravulizumab
Ravulizumab is a potent and selective complement 5 (C5) inhibitor. It is a humanized monoclonal IgG2/4 kappa antibody produced in Chinese hamster ovary (CHO) cells. Ravulizumab was engineered from eculizumab, another complement inhibitor, to increase the duration of action and reduce the frequency of drug administration. It works by blocking...
Approved
Investigational
Matched Description: … action and reduce the frequency of drug administration. ... Ravulizumab was engineered from [eculizumab], another complement inhibitor, to increase the duration of ... [L39690,L39700] Ravulizumab is currently being investigated for the treatment of Coronavirus disease …
Revefenacin
Revefenacin is a novel biphenyl carbamate tertiary amine agent that belongs to the family of the long-acting muscarinic antagonists (LAMA). The labile primary amide in the structure produces a "soft-drug" site that allows rapid systemic clearance and minimizing of the systemically mediated adverse reactions. The LAMA group falls into a...
Approved
Investigational
Matched Description: … Revefenacin is a novel biphenyl carbamate tertiary amine agent that belongs to the family of the long-acting ... LAMA group falls into a parent category known as long-acting inhaled bronchodilators and this type of ... amide in the structure produces a "soft-drug" site that allows rapid systemic clearance and minimizing of …
Rasburicase
Rasburicase is a recombinant urate-oxidase enzyme produced by a genetically modified Saccharomyces cerevisiae strain. The cDNA coding for rasburicase was cloned from a strain of Aspergillus flavus.
Approved
Investigational
Matched Description: … The cDNA coding for rasburicase was cloned from a strain of _Aspergillus flavus_. …
Retapamulin
Retapamulin, marketed by GlaxoSmithKline as the ointment Altabax, is an antibiotic for skin infections like impetigo. It was approved by the FDA in April 2007.
Approved
Aminohippuric acid
The glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity. [PubChem]
Approved
Investigational
Matched Description: … The glycine amide of 4-aminobenzoic acid. …
Vitamin E
In 1922, vitamin E was demonstrated to be an essential nutrient . Vitamin E is a term used to describe 8 different fat soluble tocopherols and tocotrienols, alpha-tocopherol being the most biologically active . Vitamin E acts as an antioxidant, protecting cell membranes from oxidative damage . The antioxidant effects...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … (R,R,R)-α-tocopherol ... (2R,4'R,8'R)-α-tocopherol …
Matched Description: … The antioxidant effects are currently being researched for use in the treatment of diseases causing bone …
Matched Description: … The antioxidant effects are currently being researched for use in the treatment of diseases causing bone …
Risankizumab
Risankizumab is a fully humanized IgG1 monoclonal antibody (mAb) directed against interleukin 23 (IL-23). It gained its first global approval in Japan in March 2019, followed by approval in Canada, the US, and Europe in April 2019. Risankizumab is used to treat plaque psoriasis, psoriatic arthritis, and Crohn's disease.[L39885,L44191,L44231] Risankizumab...
Approved
Investigational
Calcium carbimide
Calcium carbimide, sold as the citrate salt, is an alcohol-sensitizing agent. Its effects are similar to the drug disulfiram (Antabuse) in that it interferes with the normal metabolism of alcohol by preventing the breakdown of the metabolic product acetaldehyde. Calcium carbimide was conceived as an alternative for the treatment of...
Approved
Withdrawn
Matched Description: … alcohol by preventing the breakdown of the metabolic product acetaldehyde. ... The current status of calcium carbimide is cancelled post marketing.[L1113] ... effects are similar to the drug disulfiram (Antabuse) in that it interferes with the normal metabolism of …
Fluoride ion F-18
Sodium Fluoride F 18 Injection is a positron emitting radiopharmaceutical, no-carrier added. It contains radioactive fluoride F 18 that is used for diagnostic purposes in conjunction with positron emission tomography (PET) imaging and is administered by intravenous injection. Its primary indication is for bone imaging. Increased deposition around joints can...
Approved
Retifanlimab
Retifanlimab is a humanized IgG4 kappa monoclonal antibody that binds to the programmed death receptor-1 (PD-1), blocking PD-1 interaction with its ligands, programmed death-ligand 1 (PD-L1) and programmed death-ligand 2 (PD-L2). By blocking the PD-1/PD-L1/2 pathway, retifanlimab potentiates T-cell activity and boosts the immune response against cancer cells. Other monoclonal...
Approved
Investigational
Matched Description: … for the treatment of squamous carcinoma of the anal canal. ... [L45603,L45613] The use of retifanlimab in combination with other oncology drugs for the treatment of ... 2023, the FDA granted accelerated approval to retifanlimab for a different indication, the treatment of …
Benzoin resin
Benzoin resin is a balsamic resin obtained from the bark of several species of trees in the genus Styrax. There are two common kinds of benzoin, benzoin Siam and benzoin Sumatra, that are obtained from different species of the Styrax tree. While benzoin resin is used as a common ingredient...
Approved
Matched Description: … property of tape. ... species of the _Styrax_ tree. ... Benzoin resin is a balsamic resin obtained from the bark of several species of trees in the genus _Styrax …
Racephedrine
Approved
Experimental
Polysorbate 80
Polysorbate, a substance formulated by the reaction of sorbitan fatty acid ester (a nonionic surfactant) with ethylene oxide, is used in many foreign countries, including the U.S. and the EU, where it acts as an emulsifier, a solubilizer in many foods, including bread, cake mix, salad dressing, shortening oil and...
Approved
Matched Description: … Polysorbate, a substance formulated by the reaction of sorbitan fatty acid ester (a nonionic surfactant ... substance that would not normally dissolve in a particular solution is able to dissolve with the use of ... [L1852]
A solubilizing agent acts as a surfactant and increases the solubility of one agent in another …
Displaying drugs 2801 - 2825 of 9573 in total