Displaying drugs 276 - 300 of 11360 in total
Bentonite
Approved
Matched Categories: … Compounds used in a research, industrial, or household setting …
Cetalkonium
Cetalkonium is a C16 alkyl benzalkonium chloride derivative with an amphipathic property which allows it to be used in different types of formulations. It is a quaternary ammonium salt that acts as an antiseptic against a variety of bacteria and fungi. Cetalkonium is approved by the FDA for its use...
Approved
Matched Description: … [A27143] It is a quaternary ammonium salt that acts as an antiseptic against a variety of bacteria and ... Cetalkonium is a C16 alkyl benzalkonium chloride derivative with an amphipathic property which allows ... [L2137] Cetalkonium is approved by the FDA for its use in over-the-counter products as a skin protectant …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Bromothalonil
Bromothalonil, also known as Methyldibromo glutaronitrile (MDBGN), is a widely used preservative that can be found in many personal hygiene and industrial products. It is also a known allergen and dermatological irritant that has been banned in many EU countries due to increasing rates of contact allergy . In 2005,...
Approved
Experimental
Matched Description: … Sensitivity to Bromothalonil may be identified with a clinical patch test. ... Bromothalonil, also known as Methyldibromo glutaronitrile (MDBGN), is a widely used preservative that ... It is also a known allergen and dermatological irritant that has been banned in many EU countries due …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Methyltestosterone
A synthetic anabolic steroid used for treating men with testosterone deficiency or similar androgen replacement therapies. Also, has antineoplastic properties and so has been used secondarily in women with advanced breast cancer. Methyltestosterone is a schedule III drug in the US.
Approved
Matched Iupac: … ,11aS)-1-hydroxy-1,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Methyltestosterone is a schedule III drug in the US. ... A synthetic anabolic steroid used for treating men with testosterone deficiency or similar androgen replacement …
Matched Description: … Methyltestosterone is a schedule III drug in the US. ... A synthetic anabolic steroid used for treating men with testosterone deficiency or similar androgen replacement …
Dofetilide
Dofetilide is a class III antiarrhythmic agent that is approved by the Food and Drug Administration (FDA) for the maintenance of sinus rhythm in individuals prone to the formation of atrial fibrillation and flutter, and for the chemical cardioversion to sinus rhythm from atrial fibrillation and flutter.
Approved
Investigational
Matched Description: … Dofetilide is a class III antiarrhythmic agent that is approved by the Food and Drug Administration ( …
Matched Categories: … OCT2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Categories: … OCT2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Azatadine
Antihistamines such as azatadine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release.
Approved
Ixabepilone
Ixabepilone is an epothilone B analog developed by Bristol-Myers Squibb as a cancer drug. It was FDA approved on October 16, 2007, for the treatment of unresponsive aggressive metastatic or locally advanced breast cancer. Ixabepilone is administered through injection, and will be marketed under the trade name Ixempra. Ixabepilone is...
Approved
Investigational
Matched Description: … Ixabepilone is a semisynthetic analogue of epothilone B. ... Ixabepilone is an epothilone B analog developed by Bristol-Myers Squibb as a cancer drug. ... It has a lactone–lactam modification that minimizes susceptibility to esterase degradation. …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Histrelin
Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin when administered as an implant delivering continuous therapeutic doses. This drug is a synthetic analog of naturally occurring GnRH with a higher potency. Histrelin implants are non-biodegradable, diffusion-controlled, hydrogel polymer reservoirs containing histrelin acetate that...
Approved
Withdrawn
Matched Description: … This drug is a synthetic analog of naturally occurring GnRH with a higher potency. ... Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin …
Artesunate
Artesunate is indicated for the initial treatment of severe malaria. The World Health Organization recommends artesunate as first line treatment for severe malaria. Artesunate was developed out of a need for a more hydrophilic derivative of artemisinin. Artesunate was granted FDA approval on 26 May 2020.
Approved
Investigational
Matched Description: … [L890] Artesunate was developed out of a need for a more hydrophilic derivative of [artemisinin]. …
Nabumetone
Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).[label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate into ions which was believed to reduce GI toxicity by limiting local action. While slightly reduced, possibly due to a degree...
Approved
Matched Description: … acting as a potent COX inhibitor similar in structure to [naproxen]. ... Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID). ... [A179077] While slightly reduced, possibly due to a degree of cyclooxygenase-2 selectivity (COX-2), nabumetone …
Phosphoric acid
Phosphoric Acid is a colorless, odorless phosphorus-containing inorganic acid. Phosphoric acid is a sequestering agent which binds many divalent cations, including Fe++, Cu++, Ca++, and Mg++.
Approved
Matched Description: … Phosphoric Acid is a colorless, odorless phosphorus-containing inorganic acid. ... Phosphoric acid is a sequestering agent which binds many divalent cations, including Fe++, Cu++, Ca++ …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Xanthan gum
Xanthan gum is a polysaccharide gum derived from* Xanthomonas campestris* by a pure-culture fermentation process and purified by recovery with isopropyl alcohol. The major constituents include D-glucose, D-mannose, and D-glucuronic acid. Xanthan gum is a direct food additive permitted for direct addition to food for human consumption by the FDA....
Approved
Matched Description: … Xanthan gum is a polysaccharide gum derived from* Xanthomonas campestris* by a pure-culture fermentation ... It is used as a thickening agent and stabilizer in emulsions. ... Xanthan gum is a direct food additive permitted for direct addition to food for human consumption by …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Dimercaptosuccinic acid
Approved
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Prednisone
A synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver. Prednisone was granted FDA approval on 21 February 1955.
Approved
Vet approved
Matched Iupac: … hydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … A synthetic anti-inflammatory glucocorticoid derived from [cortisone]. …
Matched Description: … A synthetic anti-inflammatory glucocorticoid derived from [cortisone]. …
Cetrorelix
Cetrorelix is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH). GnRH controls another hormone that is called luteinizing hormone (LH), which is the hormone that starts ovulation during the menstrual cycle. When undergoing hormone treatment sometimes premature ovulation can occur, leading to eggs that are not...
Approved
Investigational
Matched Description: … Cetrorelix is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH). …
Almotriptan
Almotriptan is a triptan drug for the treatment of migraine headaches. Almotriptan is in a class of medications called selective serotonin receptor agonists. It works by narrowing blood vessels in the brain, stopping pain signals from being sent to the brain, and stopping the release of certain natural substances that...
Approved
Investigational
Matched Description: … Almotriptan is a triptan drug for the treatment of migraine headaches. ... Almotriptan is in a class of medications called selective serotonin receptor agonists. …
Matched Categories: … Monoamine Oxidase A Substrates …
Matched Categories: … Monoamine Oxidase A Substrates …
Aclidinium
Aclidinium is an anticholinergic for the long-term management of chronic obstructive pulmonary disease (COPD). It has a much higher propensity to bind to muscarinic receptors than nicotinic receptors. FDA approved on July 24, 2012.
Approved
Matched Description: … It has a much higher propensity to bind to muscarinic receptors than nicotinic receptors. …
Degarelix
Degarelix is used for the treatment of advanced prostate cancer. Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately causes testosterone suppression. Reduction in...
Approved
Matched Description: … Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) ... Chemically, it is a synthetic linear decapeptide amide with seven unnatural amino acids, five of which …
Nylidrin
Nylidrin, also known as buphenine belongs to the category of drugs called vasodilators, which relax blood vessels and increase blood flow. Nylidrin is a peripheral vasodilator. Some studies show the evidence of improving cognitive impairment in selected individuals, such as geriatric patients with mild to moderate symptoms of cognitive, emotional...
Approved
Matched Description: … Nylidrin is a peripheral vasodilator. …
Haemophilus influenzae type B strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen
Haemophilus influenzae type b strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is an active immunization as a booster dose given intramuscularly to pediatric patients who have received a primary series with a Haemophilus b Conjugate Vaccine that is licensed for primarly immunization. The vaccine contains Haemophilus b capsular polysaccharide...
Approved
Investigational
Matched Description: … These are heat inactivated and purified. ... booster dose given intramuscularly to pediatric patients who have received a primary series with a Haemophilus ... strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is an active immunization as a …
Methylprednisone
Methylprednisone has been used in trials studying the treatment of Leukemia, Rheumatoid Arthritis, Renal Transplantation, Kidney Transplantation, and Acute Lymphocytic Leukemia, among others.
Approved
Investigational
Matched Iupac: … hydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Chlorobutanol
Chlorobutanol, or chlorbutol, is an alcohol-based preservative with no surfactant activity . It also elicits sedative-hypnotic and weak local anesthetic actions in addition to antibacterial and antifungal properties. Similar in nature to chloral hydrate, it is formed by the simple nucleophilic addition of chloroform and acetone.
As a long-term stabilizer...
Approved
Investigational
Vet approved
Matched Description: … As a long-term stabilizer of multi-ingredient preparations, chlorobutanol is normally used at a concentration ... Due to the long terminal half-life of 37 days, the use of chlorobutanol as a sedative is limited because ... Chlorobutanol is a common detergent preservative in eye drops and other ophthalmic therapeutic formulations …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Padimate O
Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in concentrations up to 8%, as regulated by the FDA . It is a structurally-related compound to DB02362 that absorbs UV-B rays to prevent photodamage. It penetrates human skin, and is shown to induce non-ligatable strand...
Approved
Matched Description: … It is a structurally-related compound to [DB02362] that absorbs UV-B rays to prevent photodamage. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Ambenonium
Ambenonium is a cholinesterase inhibitor. It is used in the management of myasthenia gravis.
Approved
Matched Description: … Ambenonium is a cholinesterase inhibitor. It is used in the management of myasthenia gravis. …
Alogliptin
Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 (DPP-4). Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer. FDA approved January 25, 2013.
Approved
Matched Description: … Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase ... Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (> …
Displaying drugs 276 - 300 of 11360 in total