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Displaying drugs 301 - 325 of 11875 in total

Human botulinum neurotoxin A/B immune globulin

Infant botulism is a rare infectious disease occurring in infants in which Clostridium botulinum colonize the large intestine and being to produce botulinum neurotoxin directly in the gut. As these neurotoxins interfere with cholinergic nervous transmission, patients initially present with evident of loss of muscle tone (e.g. constipation, ptosis, feeding...
Approved
Matched Description: … Infant botulism is a rare infectious disease occurring in infants in which _Clostridium botulinum_ colonize ... the large intestine and being to produce botulinum neurotoxin directly in the gut. ... [L39819,L39824] BabyBIG (human-derived botulism immunoglobulin) was approved for use by the FDA in …

Curcumin

Curcumin, also known as diferuloylmethane, is an active component in the golden spice turmeric (Curcuma longa) and in Curcuma xanthorrhiza oil. It is a highly pleiotropic molecule that exhibits antibacterial, anti-inflammatory, hypoglycemic, antioxidant, wound-healing, and antimicrobial activities . Due to these properties, curcumin has been investigated for the treatment and...
Approved
Investigational
Matched Description: … longa) and in [Curcuma xanthorrhiza oil]. ... Curcumin, also known as diferuloylmethane, is an active component in the golden spice turmeric (Curcuma …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Pramipexole

Pramipexole is a drug used to treat the symptoms of Parkinson's Disease (PD). It is a non-ergot dopamine agonist drug that is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement) . It was first approved by the FDA in 1997 . Parkinson's Disease is...
Approved
Investigational
Matched Description: … to about 6.1 million in 2016 [A176861]. ... It was first approved by the FDA in 1997 [L5882]. ... in 2006 for the treatment of Restless Legs Syndrome (RLS) [A176873]. …

Enmetazobactam

Enmetazobactam is a penicillanic acid sulfone extended-spectrum beta (β)-lactamase (ESBL) inhibitor. Because ESBL enzymes can hydrolyze important antibiotics such as penicillins, broad-spectrum cephalosporins and monobactams, ESBL-producing bacteria poses challenges in the treatment of serious infections. The combination product of enmetazobactam and cefepime was first approved by the FDA on February...
Approved
Matched Description: … penicillins, broad-spectrum cephalosporins and monobactams, ESBL-producing bacteria poses challenges in …

Denileukin diftitox

A recombinant DNA-derived cytotoxic protein composed of the amino acid sequences for diphtheria toxin fragments A and B (Met 1-Thr 387)-His followed by the sequences for interleukin-2 (IL-2; Ala 1-Thr 133). It is produced in an E. coli expression system.
Approved
Investigational
Matched Description: … It is produced in an E. coli expression system. …

Frangula purshiana bark

Approved
Experimental
Matched Mixtures name: … C Ottways Lax Tab …

Almotriptan

Almotriptan is a triptan drug for the treatment of migraine headaches. Almotriptan is in a class of medications called selective serotonin receptor agonists. It works by narrowing blood vessels in the brain, stopping pain signals from being sent to the brain, and stopping the release of certain natural substances that...
Approved
Investigational
Matched Description: … Almotriptan is in a class of medications called selective serotonin receptor agonists. ... It works by narrowing blood vessels in the brain, stopping pain signals from being sent to the brain, …

Iodine

Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.[A3413,A192153,A192156,A192159]
Approved
Investigational
Matched Description: … Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer. …
Matched Mixtures name: … Ni-C-E-LE Plus ... Chela Iron Plus C,b Complex ... FLAVETTES DAILY PLUS TABLET F/C …

Latamoxef

Latamoxef is a broad- spectrum beta-lactam antibiotic similar in structure to the cephalosporins except for the substitution of an oxaazabicyclo moiety for the thiaazabicyclo moiety of certain cephalosporins. It has been proposed especially for the meningitides because it passes the blood-brain barrier and for anaerobic infections.
Approved
Investigational
Matched Description: … Latamoxef is a broad- spectrum beta-lactam antibiotic similar in structure to the cephalosporins except …

Azadirachta indica leaf

Azadirachta indica leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … Azadirachta indica leaf is a plant/plant extract used in some OTC (over-the-counter) products. …

Procaine benzylpenicillin

Procaine benzylpenicillin (INN), also known as procaine G penicillin, is an injectable antiobiotic. It is a poorly soluble salt form of penicillin which is a combination of naturally occuring benzylpenicillin (penicillin G) and the local anaesthetic agent procaine in equimolar amounts. Procaine benzylpenicillin is administered by deep intramuscular injection. It...
Approved
Vet approved
Matched Description: … It is widely used in veterinary settings. ... combination of naturally occuring benzylpenicillin (penicillin G) and the local anaesthetic agent procaine in …
Matched Mixtures name: … Bicillin C-R 900/300 …

Atezolizumab

Atezolizumab is a humanized monoclonal antibody used to prevent the interaction of PD-L1 and PD-1, removing inhibition of immune responses seen in some cancers.[A18493,L7489] This medication is reserved for patients whose tumors express PD-L1, cannot receive platinum-based chemotherapy, or whose tumors do not respond to platinum-based chemotherapy. Atezolizumab was granted...
Approved
Investigational
Matched Description: … antibody used to prevent the interaction of PD-L1 and PD-1, removing inhibition of immune responses seen in ... [L7489] In November 2022, the manufacturer (Genentech) voluntarily withdrew the use of atezolizumab for …

Teicoplanin

Teicoplanin is a glycopeptide antibiotic consisting of a mixture of several compounds, five major (named teicoplanin A2-1 through A2-5) and four minor (named teicoplanin RS-1 through RS-4). All teicoplanins share a same glycopeptide core, teicoplanin A3-1, but differ in the length and conformation of side chains attached to their β-D-glucosamine...
Approved
Investigational
Matched Description: … All teicoplanins share a same glycopeptide core, teicoplanin A3-1, but differ in the length and conformation …

Influenza A virus A/North carolina/04/2016 (H3N2) hemagglutinin antigen (MDCK cell derived, propiolactone inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …

Peginterferon beta-1a

Multiple Sclerosis (MS) is a chronic and inflammatory autoimmune disease of the central nervous system, disrupting communication between the brain and other parts of the body. Most patients diagnosed with this illness experience their initial disease symptoms between the age of 20 to 40, often the most productive years of...
Approved
Matched Description: … occur more frequently in women than in men. ... use in January 2021. ... [L5801] MS is one of the most common causes of neurological disability in young adults and is found to …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Peanut oil

Peanut oil is derived from Arachis hypogaea which can be found in South America, Mexico, and Centro America. The kernels are consumed roasted but a large percentage is used for the production of vegetable oil. The peanut oil represents about 45-52% of the kernel content and it is mainly formed...
Approved
Matched Description: … Peanut oil is derived from _Arachis hypogaea_ which can be found in South America, Mexico, and Centro ... [A33169] Under the FDA, peanut oil is categorized as an approved inactive ingredient for its use in ... [L2242] Under Health Canada, it is approved as an active ingredient in over-the-counter combination products …

Cholecalciferol

Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight . Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalciferol), are...
Approved
Nutraceutical
Matched Description: … Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there ... Appropriate levels of vitamin D must be upheld in the body in order to maintain calcium and phosphorus ... interacts with ultraviolet irradiation - like that commonly found in sunlight [L5689]. …
Matched Mixtures name: … ZYMAFLUOR D 500 C C ... C & D ... C-Nate DHA …

Tivozanib

Renal cell carcinoma (RCC) is responsible for 3% of cancer cases and is one of the 10 most common cancers in adults. The average age of diagnosis is between age 65 to 74. Tivozanib, also known as FOTIVDA, is a kinase inhibitor developed to treat adult patients with relapsed or...
Approved
Investigational
Matched Description: … carcinoma (RCC) is responsible for 3% of cancer cases[A231314] and is one of the 10 most common cancers in …

Potassium

Potassium is an essential nutrient, like Calcium and Magnesium. It was identified as a shortfall nutrient by the 2015-2020 Advisory Committee of Dietary Guidelines for Americans. Many conditions and diseases interfere with normal body potassium balance, and underconsumption of potassium is one example. Hypokalemia (low potassium) or hyperkalemia (high potassium)...
Approved
Experimental
Matched Description: … Potassium is often a key ingredient for intravenous fluids, given to patients in clinical settings for ... They are available in an assortment of tablet, injection, and other forms, depending on the setting and …
Matched Mixtures name: … C. Vit-min Formula ... Cal & Mag Hvp Chel Plus C Potass & Zinc Tab ... CALCIUM AND MAGNESIUM PLUS C,POTASSIUM AND ZINC TABLET …

Calendula officinalis flower

Calendula officinalis flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … Calendula officinalis flower is a plant/plant extract used in some OTC (over-the-counter) products. …

Secnidazole

Secnidazole is a second-generation 5-nitroimidazole antimicrobial agent. It is structurally related to other 5-nitroimidazoles, including DB00916 and DB00911, but displays improved oral absorption and a longer terminal elimination half-life than other drugs in this class. Secnidazole is selective against many anaerobic Gram-positive and Gram-negative bacteria as well as protozoa. Once...
Approved
Matched Description: … [A245503] Secnidazole has been available in many other countries in Europe, Asia, South America, and ... but displays improved oral absorption and a longer terminal elimination half-life than other drugs in ... [A245503, A245508] In September 2017, FDA approved secnidazole under the market name Solosec for the …

Dicoumarol

Dicoumarol is an oral anticoagulant agent that works by interfering with the metabolism of vitamin K. In addition to its clinical use, it is also used in biochemical experiments as an inhibitor of reductases.
Approved
Matched Description: … In addition to its clinical use, it is also used in biochemical experiments as an inhibitor of reductases …

Benzylpenicillin

Benzylpenicillin (Penicillin G) is narrow spectrum antibiotic used to treat infections caused by susceptible bacteria. It is a natural penicillin antibiotic that is administered intravenously or intramuscularly due to poor oral absorption. Penicillin G may also be used in some cases as prophylaxis against susceptible organisms. Natural penicillins are considered...
Approved
Vet approved
Matched Description: … caused by susceptible gram positive aerobic organisms, such as *Streptococcus pneumoniae*, groups A, B, C ... Penicillin G may also be used in some cases as prophylaxis against susceptible organisms. ... Natural penicillins have limited activity against gram negative organisms; however, they may be used in …
Matched Mixtures name: … Bicillin C-R 900/300 …

Rezafungin

Rezafungin is an echinocandin antifungal drug.[A258393,L45633] Unlike other echinocandins such as caspofungin and micafungin, rezafungin has long‐acting pharmacokinetics and a high stability that allows for it to have long dosing intervals maintaining high plasma exposure. Rezafungin has a half-life higher than 130 hours and can be administered once a week...
Approved
Investigational
Matched Description: … invasive candidiasis in adults with limited or no alternative treatment options. ... It can only be administered intravenously but does not reach therapeutic concentrations in the central ... [A258403] In March 2023, the FDA approved rezafungin for injection for the treatment of candidemia and …

Plantago ovata seed

Approved
Experimental
Investigational
Displaying drugs 301 - 325 of 11875 in total