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Displaying drugs 326 - 350 of 14531 in total

Hydroxycitronellal

Hydroxycitronellal is a synthetic fragrance that is widely used in many cosmetics and hygiene products such as deodorants, soaps, antiseptics, and other household items. It has the smell of lilac, lily, and lily of the valley . Hydroxycitronellal has also been shown to be a dermatologic irritant and allergen, and...
Approved
Experimental
Matched Description: … Hydroxycitronellal has also been shown to be a dermatologic irritant and allergen, and as a result commercially ... It has the smell of lilac, lily, and lily of the valley [A34269]. ... such as deodorants, soaps, antiseptics, and other household items. …

Senna leaf

Approved
Experimental
Matched Mixtures name: … SENNA LEAF and DOCUSATE SODIUM …

Attapulgite

Attapulgite is a magnesium aluminium phyllosilicate which occurs in a type of clay soil common to the Southeastern United States. When used in medicine, it physically binds to acids and toxic substances in the stomach and digestive tract. For that reason, it has often been used in antidiarrheal medications. Until...
Approved
Vet approved
Matched Description: … When used in medicine, it physically binds to acids and toxic substances in the stomach and digestive …
Matched Categories: … Alimentary Tract and Metabolism …

Magnesium acetate

Approved
Matched Mixtures name: … Normosol-M and Dextrose ... Normosol-M and Dextrose …

Pyridoxal phosphate

This is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (pyridoxamine).
Approved
Investigational
Nutraceutical
Matched Mixtures name: … Levomefolate Calcium, Pyridoxal 5-phosphate, Methylcobalamin and Schizochytrium DHA Oil …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …

Hydroflumethiazide

A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p822)
Approved
Investigational
Withdrawn
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. …
Matched Categories: … hydroflumethiazide and potassium ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Picosulfuric acid

Picosulfuric acid is found in laxative products. Sodium picosulfate is a used to treat constipation or induce colon cleansing to prepare the large bowels before colonoscopy or surgery. The combination product containing sodium picosulfate and magnesium citrate was introduced to the Canadian market in 2005 and has been used in...
Approved
Matched Description: … market in 2005 and has been used in European countries for many years. ... The combination product containing sodium picosulfate and magnesium citrate was introduced to the Canadian …
Matched Mixtures name: … Sodium Picosulfate, Magnesium Oxide and Anhydrous Citric Acid …
Matched Categories: … Alimentary Tract and Metabolism …

Pertussis vaccine

Pertussis vaccine is under investigation in clinical trial NCT01698346 (Pertussis (Tdap) Vaccination in Pregnancy).
Approved
Investigational
Matched Mixtures name: … Diphtheria and Tetanus Toxoids With Pertussis Vaccine Adsorbed …

Eszopiclone

Eszopiclone, marketed by Sepracor under the brand-name Lunesta, is a nonbenzodiazepine hypnotic drug used to treat insomnia. It is the active stereoisomer of zopiclone, belonging to the class of drugs known as cyclopyrrolones.[A179638,L6850] Cyclopyrrolone drugs demonstrate high efficacy and low toxicity , offering a safer alternative to other drugs used...
Approved
Investigational
Matched Description: … [A179638,L6850] Cyclopyrrolone drugs demonstrate high efficacy and low toxicity[A179827], offering a …
Matched Categories: … Hypnotics and Sedatives ... Zopiclone and prodrugs ... Benzodiazepine hypnotics and sedatives ... Miscellaneous Anxiolytics Sedatives and Hypnotics …

Canrenoic acid

Canrenoic acid (as the salt potassium canrenoate) is an aldosterone antagonist. Like spironolactone, it is a prodrug, which is metabolized to canrenone in the body.
Approved
Withdrawn
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …

Clofedanol

Clofedanol is a centrally-acting cough suppressant available in Canada under the trade name Ulone. It is not available in the United States.
Approved
Withdrawn
Matched Mixtures name: … Chlophedianol Hydrochloride, Dexchlorpheniramine Maleate, and Pseudoephedrine Hydrochloride …
Matched Categories: … Cough and Cold Preparations …

Xanthinol

Xanthinol is a very potent water-soluble derivative of niacin that can be found in diet supplements. It is also known as xanthinol nicotinate. Xaninthol is known to be a potent vasodilator that can easily pass through the cell membrane and once inside the cell it causes an increase in glucose...
Approved
Withdrawn
Matched Description: … Xanthinol is a very potent water-soluble derivative of niacin that can be found in diet supplements. ... L1079] Xaninthol is known to be a potent vasodilator that can easily pass through the cell membrane and ... [L1080] It was approved as a drug in 1998 in Canada and nowadays its status is cancelled post marketing …

Luteinizing hormone

Approved
Matched Mixtures name: … MENOGON 75 IU Powder and Solvent for solution for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Hydrogen fluoride

Hydrogen fluoride (Hydrofluoric acid) is a weak acid that is a precursor to almost all fluorine compounds, including pharmaceuticals such as DB00472 (Prozac). It is used as a chemical reagent in several industrial processes such as oil refinery. It is also used as etchant, cleaning agent, and a reagent to...
Approved
Investigational
Matched Description: … It is also used as etchant, cleaning agent, and a reagent to dissolve oxides and silicates. …
Matched Mixtures name: … Perfect Choice 0.717% Root and Dentin Desens …

Pancrelipase

Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands. The pancrelipase mixture was developed by Ortho-McNeil-Janssen Pharmaceuticals, Inc and FDA approved on April 12, 2010. For further information on the components of this mixture...
Approved
Investigational
Matched Description: … Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and ... [L2510] For further information on the components of this mixture please visit [DB11065], [DB11066] and ... [L2509] The pancrelipase mixture was developed by Ortho-McNeil-Janssen Pharmaceuticals, Inc and FDA approved …
Matched Mixtures name: … Pancreatin and Enzyme Formula - Tablet …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …

Lumateperone

Schizophrenia is a complex mental illness and impacts approximately 1% of the population. Although there are several antipsychotics including aripiprazole, paliperidone and clozapine available for clinical use, they are generally accompanied by significant metabolic and/or neurological adverse effects. Lumateperone is a newly approved 2nd generation antipsychotic currently indicated for the...
Approved
Investigational
Matched Description: … Schizophrenia is a complex mental illness and impacts approximately 1% of the population. ... [L10902] Although there are several antipsychotics including [aripiprazole], [paliperidone] and [clozapine ... ] available for clinical use, they are generally accompanied by significant metabolic and/or neurological …

Mepyramine

Mepyramine, or pyrilamine, targets the H1 receptor. It is a first generation antihistamine. However, it rapidly permeates the brain and so often causes drowsiness as a side effect. It has been found in over-the-counter combination products for colds and menstrual symptoms, but is considered to be an unapproved prescription medication...
Approved
Vet approved
Matched Description: … However, it rapidly permeates the brain and so often causes drowsiness as a side effect. ... It has been found in over-the-counter combination products for colds and menstrual symptoms, but is considered …
Matched Mixtures name: … Acetaminophen,Caffeine and Pyrilamine Maleate ... Pyrilamine Maleate and Phenylephrine Hydrochloride …
Matched Categories: … Hypnotics and Sedatives …

Macitentan

Macitentan is a dual endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension (PAH). It was first approved by the FDA in 2013. Macitentan differs from its predecessor bosentan in part due to its lower risk of hepatotoxicity. A combination product (Opsynvi) comprising macitentan and tadalafil was approved...
Approved
Matched Description: … A combination product (Opsynvi) comprising macitentan and [tadalafil] was approved in Canada in October …
Matched Categories: … macitentan and tadalafil …

Atracurium besylate

A non-depolarizing neuromuscular blocking agent with short duration of action. Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for elimination provide clinical advantage over alternate non-depolarizing neuromuscular blocking agents.
Approved
Matched Description: … Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for …

Diosmin

Chronic venous insufficiency is a common condition the western population. Compression and pharmacotherapy are frequently used to manage chronic venous insufficiency, improving circulation and symptoms of venous disease. Diosmin is a bioflavonoid isolated from various plants or synthesized from hesperidin. It is used for the improvement of capillary fragility or...
Approved
Investigational
Matched Description: … circulation and symptoms of venous disease. ... Compression and pharmacotherapy are frequently used to manage chronic venous insufficiency, improving ... Diosmin is widely available over-the-counter and demonstrates a favourable a favorable safety profile …
Matched Mixtures name: … VENAFIX (Diosmin and Hesperidin Tablet) …

Benzthiazide

Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat...
Approved
Matched Description: … Like other thiazides, benzthiazide promotes water loss from the body (diuretics). ... Benzthiazide is used to treat hypertension and edema. ... Thiazides also cause loss of potassium and an increase in serum uric acid. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Potassium cation

Potassium is the major cation (positive ion) inside animal cells, while sodium is the major cation outside animal cells. The concentration differences of these charged particles causes a difference in electric potential between the inside and outside of cells, known as the membrane potential. The balance between potassium and sodium...
Approved
Investigational
Matched Description: … Potassium is also an essential mineral needed to regulate water balance, blood pressure and levels of ... The balance between potassium and sodium is maintained by ion pumps in the cell membrane. ... differences of these charged particles causes a difference in electric potential between the inside and …

Diazepam

A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of gamma-aminobutyric acid activity. It is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and...
Approved
Illicit
Investigational
Vet approved
Matched Description: … premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome. ... A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and ... of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and …
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives …

Fusidic acid

An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed) It acts by inhibiting translocation during protein synthesis. It is often used topically in creams and eyedrops but is available in systemic formulations including tablets and injections.
Approved
Investigational
Matched Description: … tablets and injections. ... It is often used topically in creams and eyedrops but is available in systemic formulations including …
Matched Mixtures name: … BACTAFUZ-B Fusidic Acid and Betamethasone Valerate Cream …

Gallamine triethiodide

A synthetic nondepolarizing blocking drug. The actions of gallamine triethiodide are similar to those of tubocurarine, but this agent blocks the cardiac vagus and may cause sinus tachycardia and, occasionally, hypertension and increased cardiac output. It should be used cautiously in patients at risk from increased heart rate but may...
Approved
Matched Description: … may cause sinus tachycardia and, occasionally, hypertension and increased cardiac output. ... gallamine triethiodide are similar to those of tubocurarine, but this agent blocks the cardiac vagus and …
Matched Categories: … Quaternary Ammonium Compounds …
Displaying drugs 326 - 350 of 14531 in total