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Displaying drugs 326 - 350 of 14639 in total

Chlorhexidine

Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms. It is one of the most common skin and mucous membrane antiseptic agents in use today. The molecule itself is a cationic bis-guanide consisting of...
Approved
Vet approved
Withdrawn
Matched Description: … Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental ... [L11512] It is one of the most common skin and mucous membrane antiseptic agents in use today. ... [A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two …
Matched Mixtures name: … Pre and Post Sx Pouch ... Oral Cleansing and Suctioning System, q2 ... QCare Rx Oral Cleansing and Suctioning System …
Matched Categories: … Biguanides and Amidines ... Alimentary Tract and Metabolism ... Mouthwashes and Gargles ... Antiseptics and Disinfectants ... chlorhexidine and cetylpyridinium …
Matched Products: … Foster and Thrive ... 3M AVAGARD 9232 ANTISEPTIC HAND AND BODY WASH CLORHEXIDINE GLUCONATE 2% W/W SOLUTION BOTTE . …

Mexiletine

Antiarrhythmic agent pharmacologically similar to lidocaine. It may have some anticonvulsant properties.
Approved
Investigational

Oxytocin

Sir Henry H. Dale first identified oxytocin and its uterine contractile properties in 1906.[A229008,A228593,A229108] Like all other neurohypophysial hormones, oxytocin is composed of nine amino acids with a disulfide bridge between the Cys 1 and 6 residues.[A229008,A228593] In the mid-1950s, synthetic oxytocin was successfully synthesized by a biochemist named Vincent...
Approved
Vet approved
Matched Description: … and central effects. ... [A229008] It plays an important role in pair bonding, social cognition and functioning, and even fear ... Dale first identified oxytocin and its uterine contractile properties in 1906. …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Oxytocin and Analogues ... Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... methylergometrine and oxytocin …

Durlobactam

Durlobactam is a diazabicyclooctane non-beta-lactam, beta-lactamase inhibitor. It is typically given in combination with sulbactam to protect it from degradation by certain serine-beta-lactamases. The combination product of durlobactam and sulbactam was first approved by the FDA in May 2023. It is used to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial...
Approved
Investigational
Matched Description: … [L47336] The combination product of durlobactam and sulbactam was first approved by the FDA in May 2023 ... [A263306] It is used to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial …

Creatine

An amino acid derivative that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as creatinine in the urine.
Approved
Investigational
Nutraceutical
Matched Description: … An amino acid derivative that occurs in vertebrate tissues and in urine. …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Givosiran

Givosiran is a small interfering RNA (siRNA) directed towards 5-aminolevulinic acid synthase, a critical enzyme in the heme biosynthesis pathway. It is manufactured by Alnylam Pharmaceuticals and was first approved for use in the United States in November 2019 for the treatment of adults with acute hepatic porphyria, a genetic...
Approved
Investigational
Matched Description: … [L10202] It is manufactured by Alnylam Pharmaceuticals and was first approved for use in the United States ... genetic disorder in which the overproduction of toxic heme intermediates leads to neuro-, nephro-, and ... non-therapeutic measures (e.g. trigger avoidance), intravenous [hemin] for the treatment of attacks, and …
Matched Categories: … Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products …

Diamorphine

Diamorphine (heroin) is a narcotic analgesic that may be habit-forming. It is a controlled substance (opium derivative) listed in the U.S. Code of Federal Regulations, Title 21 Parts 329.1, 1308.11 (1987). Sale is forbidden in the United States by Federal statute. (Merck Index, 11th ed) Internationally, diamorphine is controlled under...
Approved
Illicit
Investigational
Matched Description: … As heroin, it is illegal to manufacture, possess, or sell in the United States and the UK. ... (Merck Index, 11th ed) Internationally, diamorphine is controlled under Schedules I and IV of the Single …

Oxygen

Oxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing blood flow...
Approved
Vet approved
Matched Description: … Oxygen is an element displayed by the symbol O, and atomic number 8. ... any disease that impairs the body's ability to take up and use gaseous oxygen. ... disorders (congestive heart failure), some disorders that cause increased pulmonary artery pressure, and …
Matched Mixtures name: … Carbon Dioxide and Oxygen Mixture, Compressed, Oxidizing, N.O.S. …
Matched Products: … OSSIGENO FARMA GAS MEDICAL AND TECHNICAL GASES …

Idarucizumab

Idarucizumab is a humanized monoclonal antibody fragment (Fab) derived from an immunoglobulin G1 isotype molecule that binds to and inactivates the oral anticoagulant dabigatran, thereby reversing its anticoagulant effect. As a direct acting oral anticoagulant (DOAC), one of the risks associated with the use of dabigatran includes bleeding, espeically when...
Approved
Matched Description: … dabigatran includes bleeding, espeically when given to patients at increased risk (elderly, chronic kidney ... monoclonal antibody fragment (Fab) derived from an immunoglobulin G1 isotype molecule that binds to and ... Its use is associated with immediate, complete and sustained reversal of the anticoagulant effects of …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Oprelvekin

Oprelvekin, the active ingredient in Neumega®, is recombinant Interleukin-11 (IL-11), which is produced in Escherichia coli (E. coli) by recombinant DNA technology. With a molecular mass of approximately 19,000 daltons, the non-glycosylated protein is 177 amino acids in length in comparison to the natural IL-11, which is 178 amino acid...
Approved
Investigational
Matched Description: … In mice and nonhuman primate studies of animals with moderate and severe myelosuppression, in addition ... nadirs and accelerated platelet recoveries compared to controls. ... Oprelvekin works by stimulating megakaryocytopoiesis and thrombopoiesis. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …

Sodium zirconium cyclosilicate

Sodium zirconium cyclosilicate is approved as the trade product Lokelma developed by AstraZeneca - an insoluble, non-absorbed sodium zirconium silicate, formulated as a powder for oral suspension that acts as a highly selective potassium removing agent. It is administered orally and is odorless, tasteless, and stable at room temperature. Approval...
Approved
Investigational
Matched Description: … [L2933] It is administered orally and is odorless, tasteless, and stable at room temperature. ... Approval of the medication is supported by data from three double-blind, placebo-controlled trials and ... two open-label trials which showed that the onset of action was approximately 1.0 hour and the median …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …

Daprodustat

Daprodustat is a small-molecule hypoxia-inducible factor (HIF) prolyl hydroxylase (PHD) inhibitor that was developed by GSK.[A254167,A254162] Patients with CKD cannot induce erythropoietin (EPO) production in response to hypoxia or anemia. As a potent inhibitor of PHD1, PHD2 and PHD3 (≥ 1000-fold selectivity), daprodustat stabilizes cellular HIF1α and HIF2α and the induces...
Approved
Investigational
Matched Description: … daprodustat was fully approved by the FDA as the first oral treatment for anemia caused by chronic kidney ... HIF1α and HIF2α and the induces erythropoiesis. ... As a potent inhibitor of PHD1, PHD2 and PHD3 (≥ 1000-fold selectivity), daprodustat stabilizes cellular …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …

Zoledronic acid

Zoledronic acid, or CGP 42'446, is a third generation, nitrogen containing bisphosphonate similar to ibandronic acid, minodronic acid, and risedronic acid. Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hypercalcemia of malignancy, multiple myeloma, bone metastases from solid tumors, and Paget’s disease of bone.[L13712,L13715,L13721] Zoledronic acid...
Approved
Matched Description: … of malignancy, multiple myeloma, bone metastases from solid tumors, and Paget’s disease of bone. ... third generation, nitrogen containing bisphosphonate similar to [ibandronic acid], [minodronic acid], and ... [A203111] Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hypercalcemia …
Matched Categories: … Drugs Affecting Bone Structure and Mineralization ... zoledronic acid, calcium and colecalciferol, sequential …
Matched Products: … ZOFIVE® 5 MG/100 ML SOLUCION PARA INFUSION ... POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE 4 MG / VIAL …

Acetic acid

Acetic acid is a product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed) Acetic acid otic (for the ear) is an antibiotic that treats infections caused by bacteria or...
Approved
Matched Description: … It is used locally, occasionally internally, as a counterirritant and also as a reagent. ... Acetic acid is a product of the oxidation of ethanol and of the destructive distillation of wood. …
Matched Mixtures name: … FRESENIUS CONCENTRADO ACIDO PARA HEMODIALISIS EXTRACORPOREA SKF 203 GLUCOSADO ... Hydrocortisone and Acetic Acid ... Hydrocortisone and Acetic Acid …
Matched Categories: … Indicators and Reagents ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Pirenzepine

An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also...
Approved
Matched Description: … It also potentiates the effect of other antiulcer agents such as cimetidine and ranitidine. ... It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the ... required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …

Phenformin

A biguanide hypoglycemic agent with actions and uses similar to those of metformin. Although it is generally considered to be associated with an unacceptably high incidence of lactic acidosis, often fatal, it is still available in some countries. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
Approved
Investigational
Withdrawn
Matched Description: … A biguanide hypoglycemic agent with actions and uses similar to those of metformin. …
Matched Categories: … Alimentary Tract and Metabolism ... phenformin and sulfonylureas …

Guanadrel

Guanadrel is an antihypertensive agent and postganglionic adrenergic blocking agent.
Approved
Matched Description: … Guanadrel is an antihypertensive agent and postganglionic adrenergic blocking agent. …

Damoctocog alfa pegol

In recent years, various extended half-life factor VIII and factor IX preparations have been studied and gained approval. In order to extend half-lives, techniques such as fusion to protein conjugates (Fc part of IgG1 or albumin), chemical modification (PEGylation), and protein sequence modification have been utilized. Also known as, BAY94-9027,...
Approved
Investigational
Matched Description: … and gained approval. ... has been filed with the FDA in August 2017 and FDA approved in August 2018. ... In recent years, various extended half-life factor VIII and factor IX preparations have been studied …

Progesterone

Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy. A low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss . Progesterone is used in various contraceptive preparations to prevent ovulation...
Approved
Vet approved
Matched Description: … , embryo implantation, and the successful establishment of pregnancy. ... ], [A175612] as well as in other formulations to promote and support pregnancy. ... Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity …
Matched Mixtures name: … Estradiol and Progesterone …
Matched Categories: … progesterone and estrogen ... Progesterone and Derivatives ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Viltolarsen

Duchenne muscular dystrophy (DMD) is an X-linked recessive allelic disorder characterized by a lack of functional dystrophin protein, which leads to progressive ambulatory, pulmonary, and cardiac function and is invariably fatal. A related, albeit a less severe, form of muscular dystrophy known as Becker muscular dystrophy (BMD) is characterized by...
Approved
Investigational
Matched Description: … [A218186, L15526] In this manner, PMOs are much less susceptible to endo- and exonucleases and exhibit ... cardiac function and is invariably fatal. ... dystrophy known as Becker muscular dystrophy (BMD) is characterized by the production of shortened and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Dutasteride

Dutasteride is an oral synthetic 4-azasteroid commonly marketed under the trade name Avodart. It is a novel dual 5α-reductase inhibitor that works by blocking both isoforms of 5α-reductase enzymes in a potent, selective, and irreversible manner. Type I and II 5α-reductase enzymes convert testosterone into dihydrotestosterone (DHT), a primary hormonal...
Approved
Investigational
Matched Description: … hormonal mediator that plays a role in the development and enlargement of the prostate gland. ... [A1909] Type I and II 5α-reductase enzymes convert testosterone into dihydrotestosterone (DHT), a primary ... 5α-reductase inhibitor that works by blocking both isoforms of 5α-reductase enzymes in a potent, selective, and …
Matched Mixtures name: … Dutasteride and tamsulosin hydrochloride ... Dutasteride and Tamsulosin Hydrochloride ... Dutasteride and tamsulosin hydrochloride …
Matched Categories: … tamsulosin and dutasteride ... Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Pentoxifylline

Pentoxifylline (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and also has both anti-oxidant and anti-inflammatory properties.[A226415, L30300] Although originally developed to treat intermittent claudication, a form of exertion-induced leg pain common in patients with peripheral arterial disease, PTX has been investigated for its possible...
Approved
Investigational
Matched Description: … been investigated for its possible use in diverse conditions, including osteoradionecrosis, diabetic kidney ... also has both anti-oxidant and anti-inflammatory properties. ... disease, and generally any condition associated with fibrosis. …

Procainamide

A derivative of procaine with less CNS action.
Approved
Matched Categories: … para-Aminobenzoates ... Benzamides and benzamide derivatives …

Beremagene geperpavec

Beremagene geperpavec is a live, replication-defective herpes simplex virus type 1 (HSV-1)-based vector therapy. Developed by Krystal Biotech, it was first approved by the FDA on May 19, 2023, for the treatment of wounds associated with dystrophic epidermolysis bullosa (DEB). DEB is caused by mutations in the COL7A1 gene that...
Approved
Matched Description: … Beremagene geperpavec is a live, replication-defective herpes simplex virus type 1 (HSV-1)-based vector …
Matched Categories: … Cellular and Gene Therapy ... Preparations for Treatment of Wounds and Ulcers …

Moxidectin

Moxidectin is a potent, broad-spectrum endectocide (antiparasitic that is active against endo- and ecto-parasites) with activity against nematodes, insects, and acari. It was first used in cattle followed by an approved use in general animals. It is a semi-synthetic methoxine derivative of nemadectin which is a 16-member pentacyclic lactone of...
Approved
Investigational
Vet approved
Matched Description: … ) with activity against nematodes, insects, and acari. ... Moxidectin is a potent, broad-spectrum endectocide (antiparasitic that is active against endo- and ecto-parasites ... [A33385] Moxidectin was developed by Medicines Development for Global Health and FDA approved in June …
Matched Mixtures name: … Advocate Spot-on Solution for Small Cats and Ferrets …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Displaying drugs 326 - 350 of 14639 in total