Advanced Filter

Filter by Group

Filter by Market Availability

Displaying drugs 351 - 375 of 6246 in total
Pargyline is a monoamine oxidase inhibitor with antihypertensive properties.
Approved
Matched Iupac: … benzyl(methyl)(prop-2-yn-1-yl)amine …
Matched Description: … Pargyline is a monoamine oxidase inhibitor with antihypertensive properties. …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Camphor is a bicyclic monoterpene ketone found widely in plants, especially Cinnamomum camphora. It is used topically as a skin antipruritic and as an anti-infective agent. When ingested, camphor has a rapid onset of toxic effects, and camphorated oil is the product most often responsible for its toxicity. The FDA...
Approved
Withdrawn
Matched Synonyms: … (+)-bornan-2-one …
Matched Iupac: … (1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one …
Matched Description: … concentration higher than 11%. ... It is used topically as a skin antipruritic and as an anti-infective agent. ... Camphor is a bicyclic monoterpene ketone found widely in plants, especially _Cinnamomum camphora_. …
Matched Mixtures name: … Cm Systems 2 Gel ... Vaporizing Chest Rub 4 oz. 3 pk ... Pain-A-trate Cream …
Matched Products: … Formula A ... CBD Clinic Pain Relief - Level 2 ... CBD Clinic Deep-Rub Pain Relief - Level 1
Centella asiatica is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Investigational
Matched Description: … Centella asiatica is a plant/plant extract used in some OTC (over-the-counter) products. …
Matched Products: … Centellaca A Clear Relaxing Toner ... MADEGSOLE %1 MERHEM, 1 ADET ... MADEGCENTA %1 MERHEM, 1 ADET …
Cladribine is a purine analogue or a chlorinated derivative of adenine that causes apoptosis of B and T lymphocytes. Cladribine was first approved in the United States in 1993 initially as a treatment for a number of hematological malignancies; currently, it is approved for the treatment of hairy cell leukemia....
Approved
Investigational
Matched Synonyms: … (2R,3S,5R)-5-(6-amino-2-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol ... 2-Chloro-2'-deoxyadenosine ... 2-chloro-2′-deoxy-adenosine …
Matched Iupac: … (2R,3S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol …
Matched Description: … of B and T lymphocytes. ... [A263733] In 2017 in Europe and in 2019 in the United States, cladribine was also approved for the treatment ... Cladribine is a purine analogue or a chlorinated derivative of adenine [A263733] that causes apoptosis …
Matched Categories: … 2-Chloroadenosine ... Heterocyclic Compounds, 2-Ring …
Matched Products: … MAVENCLAD 10 MG TABLET, 1 ADET ... OCLADRA 2MG/ML ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON ,FLAKON, 1 ADET …
Approved
Experimental
Matched Mixtures name: … Multilax 1 Cap …
Matched Products: … Hermes 11 Tea …
Voriconazole (Vfend, Pfizer) is a triazole antifungal medication used to treat serious fungal infections. It is used to treat invasive fungal infections that are generally seen in patients who are immunocompromised. These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections. The increased affinity of voriconazole for 14-alpha sterol demethylase...
Approved
Matched Synonyms: … (αR,βS)-α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol ... (R-(R*,S*))-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol …
Matched Iupac: … (3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol …
Matched Description: … Voriconazole (Vfend, Pfizer) is a triazole antifungal medication used to treat serious fungal infections …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … VOSICAZ ® 200MG POLVO PARA RECONSTITUIR A SOLUCIÒN INYECTABLE ... NEUCLER® 200 MG POLVO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE PARA INFUSIÓN …
Brincidofovir is an oral antiviral drug used in the treatment of human smallpox infections. It is a lipid conjugate pro-drug of the acyclic nucleotide analogue cidofovir[L34404,A235725] - this lipid conjugate improves drug delivery to the target cells and significantly reduces the nephrotoxicity typically associated with cidofovir therapy.[A235725,A235735] Due to its...
Approved
Investigational
Matched Iupac: … ({[(2S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)[3-(hexadecyloxy) …
Matched Description: … (BKV), adenoviruses (AdV), and Epstein-Barr virus (EBV), amongst others. ... [A235725,A235735] Due to its formulation as a pro-drug brincidofovir also carries a greater bioavailability ... resulting in brincidofovir being investigated for the prevention and treatment of cytomegalovirus (CMV), BK Virus
Matched Categories: … Heterocyclic Compounds, 1-Ring …
An anthracenedione-derived antineoplastic agent.
Approved
Investigational
Matched Synonyms: … 1,4-Bis(2-(2-hydroxyethylamino)ethyl)amino)-5,8-dihydroxyanthraquinone …
Matched Iupac: … 1,4-dihydroxy-5,8-bis({2-[(2-hydroxyethyl)amino]ethyl}amino)-9,10-dihydroanthracene-9,10-dione …
Matched Salts cas: … 70476-82-3
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic Index …
Matched Products: … MITOXANTRONE BAXTER INJECTION 2 mg/ml ... MİTOXANTRONE BAXTER 20 MG/10 ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... Ebexantron 2 mg/ml - Konzentrat zur Herstellung einer Infusionslösung …
Ezetimibe is a lipid-lowering compound that inhibits intestinal cholesterol and phytosterol absorption. The discovery and research of this drug began in the early 1990s, after the intravenous administration of radiolabelled ezetimibe in rats revealed that it was being localized within enterocytes of the intestinal villi - this prompted studies investigating...
Approved
Matched Iupac: … (3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2- …
Matched Description: … distinct mechanism of action involving the sterol transporter Niemann-Pick C1-Like 1 (NPC1L1), and is ... Ezetimibe is a lipid-lowering compound that inhibits intestinal cholesterol and phytosterol absorption ... [A15202] Ezetimibe is used as an adjunctive therapy to a healthy diet to lower cholesterol levels in …
Matched Mixtures name: … TIAZOMET ® A 40/10 TABLETAS …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis.[A3811, A260880, L40968] Abiraterone was first approved by the FDA and EMA on April, July, and September 2011, respectively. It is used to treat metastatic...
Approved
Matched Synonyms: … (3β)-17-(pyridin-3-yl)androsta-5,16-dien-3-ol ... 17-(3-Pyridyl)androsta-5,16-dien-3beta-ol …
Matched Iupac: … (3aS,3bR,7S,9aR,9bS,11aS)-9a,11a-dimethyl-1-(pyridin-3-yl)-3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H, ... 11aH-cyclopenta[a]phenanthren-7-ol …
Matched Description: … Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17 …
Matched Salts cas: … 154229-18-2
Benzyl benzoate is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei. It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection. Benzyl benzoate is lethal to this mite and so...
Approved
Matched Description: … Scabies is a skin infection caused by the mite sarcoptes scabiei. ... It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary …
Matched Categories: … Compounds used in a research, industrial, or household setting …
A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of leukemia and other neoplasms.
Approved
Matched Synonyms: … -trihydroxy-1-methoxy-5,12-napthacenedione ... (8S-cis)-8-acetyl-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyrannosyl)oxy)-7,8,9,10-tetrahydro-6,8,11 …
Matched Iupac: … (8S,10S)-8-acetyl-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-1-methoxy …
Matched Description: … A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others …
Matched Salts cas: … 371770-68-2
Matched Categories: … BSEP/ABCB11 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … ENJEKSİYON İÇİN LİYOFILIZE TOZ, 1 ADET ... AL DAUNO® 20MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE …
Anagrelide is a platelet-reducing agent used to lower dangerously elevated platelet levels (i.e. to treat thrombocythemia) in patients with myeloproliferative neoplasms. It is an oral imidazoquinazoline that was first approved for use in the US in 1997. It appears to carry a better response rate than other thrombocythemia treatments (e.g....
Approved
Matched Iupac: … 6,7-dichloro-1H,2H,3H,5H-imidazo[2,1-b]quinazolin-2-one …
Matched Description: … Anagrelide is a platelet-reducing agent used to lower dangerously elevated platelet levels (i.e. to treat ... [A214274] It appears to carry a better response rate than other thrombocythemia treatments (e.g. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Phosphodiesterase 3 Inhibitors ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index …
Matched Products: … ANAGRELID RATIO 1 MG ... Anagrelid Nordic 1 mg Tabletten ... Anagrelid ratiopharm 1 mg Hartkapseln …
Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is administered orally as the prodrug, candesartan cilexetil, which is rapidly converted to its active metabolite, candesartan, during absorption in the gastrointestinal tract. Candesartan lowers blood pressure by antagonizing the renin-angiotensin-aldosterone...
Approved
Matched Iupac: … 1-{[(cyclohexyloxy)carbonyl]oxy}ethyl 2-ethoxy-1-{[2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl …
Matched Description: … renin-angiotensin-aldosterone system (RAAS); it competes with angiotensin II for binding to the type-1
Matched Mixtures name: … CANDEPREX H® ... CANDEPREX H® ... CANDAM ® H 5/32/12.5 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Angiotensin 2 Receptor Blocker ... Heterocyclic Compounds, 2-Ring …
Matched Products: … Candeblo 2 mg - Tabletten ... Candesartan G.L. 2 mg - Tabletten ... Candesartan A-med 8 mg Tabletten …
Tetraferric tricitrate decahydrate is an iron containing phosphate binder used to treat hyperphosphatemia and iron deficiency anemia in adults with chronic kidney disease. Tetraferric tricitrate decahydrate was granted FDA approval on 5 September 2014.
Approved
Matched Iupac: … tetrairon(3+) tris(2-oxidopropane-1,2,3-tricarboxylate) decahydrate …
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
Approved
Vet approved
Matched Iupac: … 4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole …
Matched Description: … An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and …
Matched Salts cas: … 145108-58-3
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Adrenergic alpha-2 Receptor Agonists ... Central alpha-2 Adrenergic Agonist …
Matched Products: … DEXMEDETOMIDINA B. BRAUN ... SEMOTİDİN 200 MCG/50 ML IV İNFÜZYONLUK ÇÖZELTİ, 1 ADET ... SEMOTİDİN 400 MCG/100 ML IV İNFÜZYONLUK ÇÖZELTİ, 1 ADET …
A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties. Having been developed in the 1980s by GlaxoSmithKline and approved by the US FDA since January 1991, ondansetron has...
Approved
Withdrawn
Matched Iupac: … 9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-2,3,4,9-tetrahydro-1H-carbazol-4-one …
Matched Description: … A competitive serotonin type 3 receptor antagonist. ... single dose, due to a high risk of QT prolongation. ... 1980s by GlaxoSmithKline and approved by the US FDA since January 1991, ondansetron has demonstrated a
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Serotonin 3 Receptor Antagonists …
Matched Products: … Ondansetron B. Braun 2 mg/ml Injektionslösung ... ONDANSETRON B. BRAUN SOLUTION FOR INJECTION OR INFUSION 2 MG/ML ... LAUFRAN 4 MG/2 ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET …
Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells. It works by promoting the division and differentiation of committed erythroid progenitors in the bone marrow [FDA Label]. Epoetin alfa (Epoge) was developed by Amgen Inc. in 1983 as the first rhEPO...
Approved
Matched Description: … Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red ... Epoetin alfa is a 165-amino acid erythropoiesis-stimulating glycoprotein produced in cell culture using ... various clinical conditions, such as chronic renal failure, antiviral drug therapy, chemotherapy, or a
Matched Products: … Binocrit 2,000 IU/1 ml solution for injection in a pre-filled syringe ... Binocrit 10 000 IU/1 ml solution for injection in a pre-filled syringe ... Binocrit 40, 000 IU/1 ml solution for injection in a pre-filled syringe …
Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin) is the 5-formyl derivative of tetrahydrofolic acid, a necessary co-factor in the body. Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the...
Approved
Matched Synonyms: … N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid …
Matched Iupac: … (2S)-2-[(4-{[(2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}phenyl)formamido …
Matched Description: … Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary ... Folic acid is an essential B vitamin required by the body for the synthesis of purines, pyrimidines, ... This results in a deficiency of coenzymes and a resultant buildup of toxic substances that are responsible …
Matched Categories: … Vitamin B Complex ... Heterocyclic Compounds, 2-Ring ... Compounds used in a research, industrial, or household setting …
Matched Products: … NYRIN INJECTION 3 mg/ml ... FOLINATO DE CALCIO (EQUIVALENTE A ACIDO FOLINICO 50 MG/5ML ... KALSIYUM FOLINAT EBEWE 30 MG/3 ML ENJEKTABL ÇÖZELTİ İÇEREN AMPUL, 5 ADET …
Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections. Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue.
Approved
Matched Synonyms: … 9-[2-hydroxy-1-(hydroxymethyl)-ethoxymethyl]guanine ... 9-(4-hydroxy-3-hydroxymethylbut-1-yl)-guanine ... 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine …
Matched Iupac: … 2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-6,9-dihydro-3H-purin-6-one …
Matched Description: … of various herpes simplex virus (HSV) infections. ... Displaying low toxicity and good selectivity, penciclovir is a nucleoside analogue. ... Penciclovir is a synthetic acyclic guanine derivative with antiviral activity used for the treatment …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … EX-LOVIR % 1 KREM 2 G ... PENSIVIR %1 KREM , 2 G ... VECTAVIR % 1 KREM, 2 G …
Approved
Matched Iupac: … 2,3,4,5-tetrachloro-6-[6-hydroxy-2,4,5,7-tetra(¹³¹I)iodo-3-oxo-3H-xanthen-9-yl]benzoic acid …
Immunosuppressive dimeric fusion protein that consists of the extracellular CD2-binding portion of the human leukocyte function antigen-3 (LFA-3) linked to the Fc (hinge, CH2 and CH3 domains) portion of human IgG1. Produced by CHO cells, mW is 91.4 kD.
Approved
Investigational
Withdrawn
Matched Description: … -3 (LFA-3) linked to the Fc (hinge, CH2 and CH3 domains) portion of human IgG1. ... fusion protein that consists of the extracellular CD2-binding portion of the human leukocyte function antigen
Matched Categories: … CD2-directed LFA-3/Fc Fusion Protein …
Bemiparin is an antithrombotic and belongs to the group of drugs known as the low molecular weight heparins (LMWH). Like semuloparin, bemiparin is classified as an ultra-LMH because of its low mean molecular mass of 3600 daltons, which is a unique property of this class . These heparins have lower...
Approved
Investigational
Matched Description: … bemiparin is classified as an ultra-LMH because of its low mean molecular mass of 3600 daltons, which is a
Matched Products: … HIBOR 2500 IU/0,2 ML KULLANIMA HAZIR 2 ENJEKTOR ... HIBOR 5000 IU/0,2 ML SC KULLANIMA HAZIR ENJEKTÖR, 2 ADET ... HIBOR 10000 IU/0,4 ML SC KULLANIMA HAZIR ENJEKTÖR, 2 ADET …
Bedaquiline is a bactericidal antimycobacterial drug belonging to the class of diarylquinoline. The quinolinic central heterocyclic nucleus with alcohol and amine side chains is responsible for bedaquiline-mediated antimycobacterial activity. Although it is closely related to fluoroquinolones, bedaquiline does not affect DNA gyrase; instead, bedaquiline inhibits the c subunit of ATP...
Approved
Matched Synonyms: … 1-(6-Bromo-2-methoxy-quinolin-3-yl)-4-dimethylamino-2-naphthalen-1-yl-1-phenyl-butan-2-ol …
Matched Iupac: … (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol …
Matched Description: … [L48506] Although the current standard of TB treatment of anti-TB drugs for 2 months, including 2 key ... Bedaquiline is a bactericidal antimycobacterial drug belonging to the class of diarylquinoline. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
The Pfizer-BioNTech COVID-19 vaccine (also known as BNT162b2, Tozinameran, and Comirnaty), is one of four advanced mRNA-based vaccines developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002,L15007,L36025] Comirnaty is a nucleoside modified mRNA (modRNA) vaccine encoding an optimized full-length version of the severe acute respiratory syndrome coronavirus 2...
Approved
Investigational
Matched Description: … It is designed to induce immunity against SARS-CoV-2, the virus responsible for causing COVID-19. ... virus from one individual to another. ... [A225386] Comirnaty was granted a EUA in the UK on December 2, 2020,[L26676] and in Canada on December …
Matched Mixtures name: … Comirnaty Original/omicron Ba.1
Displaying drugs 351 - 375 of 6246 in total