Displaying drugs 376 - 400 of 6814 in total
Aripiprazole lauroxil
Aripiprazole lauroxil is a long-acting injectable atypical antipsychotic drug used in the treatment of schizophrenia in adult patients. It is a prodrug of aripiprazole, which acts as a partial agonist at the D2 and 5-HT1A receptors, and as an antagonist at the 5-HT2A receptors .
Affecting about 1% of the...
Approved
Investigational
Matched Description: … as an antagonist at the 5-HT2A receptors [A34289]. ... It is a prodrug of [aripiprazole], which acts as a partial agonist at the D2 and 5-HT1A receptors, and …
Matched Categories: … Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists …
Matched Categories: … Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists …
Dacomitinib
Dacomitinib, designed as (2E)-N-16-4-(piperidin-1-yl) but-2-enamide, is an oral highly selective quinazalone part of the second-generation tyrosine kinase inhibitors which are characterized by the irreversible binding at the ATP domain of the epidermal growth factor receptor family kinase domains. Dacomitinib was developed by Pfizer Inc and approved by the FDA on...
Approved
Investigational
Avapritinib
Avapritinib, or BLU-285, is a selective tyrosine kinase inhibitor of KIT and platelet derived growth factor receptor alpha indicated for the treatment of unresectable, metastatic gastrointestinal stromal tumors and advanced systemic mastocytosis.[A189339,L40363] It is one of the first medications available for the treatment of multidrug resistant cancers. Avapritinib shares a...
Approved
Investigational
Matched Iupac: … fluorophenyl)-1-(2-{4-[6-(1-methyl-1H-pyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]piperazin-1-yl}pyrimidin-5- …
Exenatide
Exenatide is a glucagon-like peptide-1 (GLP-1) analog . It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows gastric emptying to improve glycemic control . Exenatide was given FDA approval on April 28, 2005 . It is available as immediate- and extended-release formulations.[L42685,L42690] Bydureon, the brand...
Approved
Investigational
Matched Products: … BYETTA 5 µG/20 µL SC KULLANIMA HAZIR DOLU ENJEKSİYON KALEMI ICINDE COZELTI, 1.2 ML (60 DOZ) …
Methionine
A sulfur containing essential amino acid that is important in many body functions. It is a chelating agent for heavy metals.
Approved
Nutraceutical
Matched Mixtures name: … Aminosyn II 7% With 50% Dextrose ... Aminosyn II 8.5% With 50% Dextrose ... Aminosyn 5% …
Phenoxymethylpenicillin
Phenoxymethylpenicillin is a narrow spectrum antibiotic also commonly referred to as Penicillin V or Penicillin VK. It is a phenoxymethyl analog of Penicillin G, or benzylpenicillin. An orally active naturally penicillin, phenoxymethylpenicillin is used to treat mild to moderate infections in the respiratory tract, skin, and soft tissues caused by...
Approved
Vet approved
Matched Products: … Star Pen 250 mg/5 ml - Trockensirup ... ./5 ML ŞURUP HAZIRLAMAK İÇİN KURU TOZ, 150 ML ... CLIACIL 300000 IU/5 ML ŞURUP HAZIRLAMAK İÇİN KURU TOZ, 150 ML …
Cilgavimab
SARS-CoV-2, the causative agent of COVID-19, enters cells via the interaction between the trimeric spike (S) glycoprotein and host cell angiotensin-converting enzyme 2 (ACE2). Blocking the interaction between the receptor-binding domain (RBD) of the S1 subunit and ACE2 inhibits viral host cell entry; animal studies indicate that antibodies capable of...
Approved
Investigational
Tixagevimab
SARS-CoV-2, the causative agent of COVID-19, enters cells via the interaction between the trimeric spike (S) glycoprotein and host cell angiotensin-converting enzyme 2 (ACE2). Blocking the interaction between the receptor-binding domain (RBD) of the S1 subunit and ACE2 inhibits viral host cell entry; animal studies indicate that antibodies capable of...
Approved
Investigational
Povidone
Povidone, also known as polyvinylpyrrolidone (PVP) or polyvidone, is a synthetic water-soluble polymer made from the monomer N-vinylpyrrolidone used as a binder in many pharmaceutical tablets and lubricant in eye drops. It is also used in many technical applications with various roles as an adhesive, additive, and emulsifier. When in...
Approved
Withdrawn
Matched Products: … OCULOTECT FLUID % 5 STERIL GÖZ DAMLA, 10 ML …
Chlorobutanol
Chlorobutanol, or chlorbutol, is an alcohol-based preservative with no surfactant activity . It also elicits sedative-hypnotic and weak local anesthetic actions in addition to antibacterial and antifungal properties. Similar in nature to chloral hydrate, it is formed by the simple nucleophilic addition of chloroform and acetone.
As a long-term stabilizer...
Approved
Investigational
Vet approved
Matched Salts cas: … 6001-64-5 …
Hydroxyethyl cellulose
Hydroxyethyl cellulose is a polysaccharide derivative with gel thickening, emulsifying, bubble-forming, water-retaining and stabilizing properties. It is used as a key ingredient in many household cleaning products, lubricants and cosmetics due to its non-ionic and water-soluble nature. It is often used as an ingredient in ophthalmic pharmaceutical preparations such as...
Approved
Matched Salts name: … Hydroxyethyl cellulose (140 MPa.s at 5%) ... Hydroxyethyl cellulose (280 MPa.s at 5%) …
Maralixibat
Maralixibat (also known as SHP625, LUM001, and lopixibat) is an ileal bile acid transporter inhibitor, like odevixibat.[A236823,A239249,L38834] Maralixibat is indicated for the treatment of cholestatic pruritus in patients with Alagille syndrome. Previously, patients with cholestatic pruritus associated with Alagille syndrome were treated with antihistamines, rifampin, ursodeoxycholic acid, cholestyramine, naltrexone, and...
Approved
Investigational
Matched Iupac: … [(4R,5R)-3,3-dibutyl-7-(dimethylamino)-4-hydroxy-1,1-dioxo-2,3,4,5-tetrahydro-1lambda6-benzothiepin-5- …
Interferon alfa-n3
Purified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD).
Approved
Investigational
Thiethylperazine
A dopamine antagonist that is particularly useful in treating the nausea and vomiting associated with anesthesia, mildly emetic cancer chemotherapy agents, radiation therapy, and toxins. This piperazine phenothiazine does not prevent vertigo or motion sickness. (From AMA Drug Evaluations Annual, 1994, p457)
Approved
Withdrawn
Mestranol
The 3-methyl ether of ethinyl estradiol. It must be demethylated to be biologically active. It is used as the estrogen component of many combination ORAL contraceptives.
Approved
Matched Mixtures name: … Norinyl 1/50 28 Tab ... Norinyl 1/50 21 Tab ... Norinyl 1/50 -(21-day Regimen) …
Remestemcel-L
Remestemcel-L is a third-party, off-the-shelf suspension of ex-vivo cultured adult human mesenchymal stem cells intended for intravenous infusion. The mesenchymal stem cells are derived from the bone marrow of unrelated and human leukocyte antigen (HLA)–unmatched healthy adult donors and have the ability to differentiate into different tissue cells. It was...
Approved
Investigational
Matched Description: … other immunosuppressive agents are commonly used as first-line treatments to manage aGvHD, about 30-50% ... refractory aGvHD that do not respond to steroid therapy have expected one-year survival rates of only 5% …
Lopinavir
Lopinavir is an antiretroviral protease inhibitor used in combination with other antiretrovirals in the treatment of HIV-1 infection. Lopinavir is marketed and administered exclusively in combination with ritonavir - this combination, first marketed by Abbott under the brand name Kaletra in 2000, is necessary due to lopinavir's poor oral bioavailability...
Approved
Matched Iupac: … (2S)-N-[(2S,4S,5S)-5-[2-(2,6-dimethylphenoxy)acetamido]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2- …
Matched Mixtures name: … ./50 มก.) ... LOPARTA 200/50 ... LOPIVIA 200/50 …
Matched Mixtures name: … ./50 มก.) ... LOPARTA 200/50 ... LOPIVIA 200/50 …
Tetracaine
Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.
Approved
Vet approved
Matched Products: … Pontocaine 5 mg/ml …
Elbasvir
Elbasvir is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C, an infectious liver disease caused by infection with hepatitis C virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in...
Approved
Matched Iupac: … -2-yl]-1H-imidazol-5-yl}-9-phenyl-8-oxa-10-azatetracyclo[8.7.0.0^{2,7}.0^{11,16}]heptadeca-1(17),2(7) ... methyl N-[(2S)-1-[(2S)-2-{5-[(9S)-14-{2-[(2S)-1-[(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl]pyrrolidin ... ,3,5,11(16),12,14-heptaen-5-yl]-1H-imidazol-2-yl}pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate …
Matched Mixtures name: … ZEPATIER 50 MG/100 MG FİLM KAPLI TABLET, 28 ADET …
Matched Mixtures name: … ZEPATIER 50 MG/100 MG FİLM KAPLI TABLET, 28 ADET …
Viloxazine
Viloxazine is a selective norepinephrine reuptake inhibitor. For decades, an immediate-release formulation of viloxazine has been used in Europe as an antidepressant. It was first approved in the UK in 1974; however, the immediate-release formulation was discontinued due to business reasons unrelated to drug safety and efficacy. In the US,...
Approved
Investigational
Withdrawn
Drometrizole trisiloxane
Drometrizole trisiloxane is a photostable UVA and UVB light filter [A33069, L2780, L2781, L2782, L2783, F81]. The compound is a lipophilic benzotriazole derivative marketed as Meroxyl XL by L'Oreal, although sunscreens with drometrizole trisiloxane are currently only approved for use in the EU, Canada, Australia, and Japan, among other countries....
Approved
Matched Mixtures name: … Anthelios 50+ ... SPF 50+ Kids Lotion ... Fps 50 Lait Solaire …
Ensulizole
Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that absorbs strongly at UV-B wavelengths. It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter compounds due to its minimal protection against UV-A wavelengths. Due to its water solubility, ensulizole is commonly...
Approved
Matched Description: … Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that …
Matched Mixtures name: … Everlasting Cushion Fps 50 / SPF 50 ... SPF 50 Uva/uvb ... SPF 50 Uva/uvb …
Matched Mixtures name: … Everlasting Cushion Fps 50 / SPF 50 ... SPF 50 Uva/uvb ... SPF 50 Uva/uvb …
Magnesium trisilicate
Magnesium trisilicate is an inorganic compound that is used as an antacid in the treatment of peptic ulcers.
Approved
Citalopram
Citalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs.[A261316,A14720] Citalopram enhances serotonergic transmission through the...
Approved
Matched Iupac: … 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile …
Matched Categories: … Serotonin 5-HT2 Receptor Antagonists …
Matched Categories: … Serotonin 5-HT2 Receptor Antagonists …
Sodium acetate
Sodium Acetate is chemically designated CH3COONa, a hygroscopic powder very soluble in water. Sodium acetate could be used as additives in food, industry, concrete manufacture, heating pads and in buffer solutions. Medically, sodium acetate is important component as an electrolyte replenisher when given intravenously. It is mainly indicated to correct...
Approved
Investigational
Matched Mixtures name: … Dextrose 50% Inj W Electrolytes PF Abbovac ... Isolyte R In 5% Dextrose ... Isolyte M In 5% Dextrose …
Displaying drugs 376 - 400 of 6814 in total