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Displaying drugs 451 - 475 of 12592 in total
Deferoxamine
Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
Approved
Investigational
Talbutal
Talbutal, also called 5-allyl-5-sec-butylbarbituric acid, is a barbiturate with a short to intermediate duration of action. Talbutal is a schedule III drug in the U.S.
Approved
Illicit
Matched Iupac: … 5-(butan-2-yl)-5-(prop-2-en-1-yl)-1,3-diazinane-2,4,6-trione …
Matched Description: … also called 5-allyl-5-sec-butylbarbituric acid, is a barbiturate with a short to intermediate duration of …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … also called 5-allyl-5-sec-butylbarbituric acid, is a barbiturate with a short to intermediate duration of …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Peginterferon beta-1a
Multiple Sclerosis (MS) is a chronic and inflammatory autoimmune disease of the central nervous system, disrupting communication between the brain and other parts of the body. Most patients diagnosed with this illness experience their initial disease symptoms between the age of 20 to 40, often the most productive years of...
Approved
Matched Description: … forms of MS. ... [L5801] MS is one of the most common causes of neurological disability in young adults and is found to ... 20 to 40, often the most productive years of life. …
Matched Mixtures name: … ADET 63 MGC/0.5 ML+1 ADET 94 MCG/0.5 ML ... ADET 63 MGC/0.5 ML+1 ADET 94 MCG/0.5 ML ... 0.5 ML+94 MCG/0.5 ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM TEDAVİYE BAŞLAMA PAKETİ , 1 …
Matched Mixtures name: … ADET 63 MGC/0.5 ML+1 ADET 94 MCG/0.5 ML ... ADET 63 MGC/0.5 ML+1 ADET 94 MCG/0.5 ML ... 0.5 ML+94 MCG/0.5 ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM TEDAVİYE BAŞLAMA PAKETİ , 1 …
Oxyquinoline
Oxyquinoline is a heterocyclic phenol and derivative of quinoline with antiseptic, disinfectant, and pesticide properties. It is used as a stabilizer for hydrogen peroxide, where it is sometimes added in cosmetic products.
Approved
Vet approved
Matched Description: … Oxyquinoline is a heterocyclic phenol and derivative of quinoline with antiseptic, disinfectant, and …
Infigratinib
Infigratinib is a pan-fibroblast growth factor receptor (FGFR) kinase inhibitor. By inhibiting the FGFR pathway, which is often aberrated in cancers such as cholangiocarcinoma, infigratinib suppresses tumour growth. Cholangiocarcinoma is the most common primary malignancy affecting the biliary tract and the second most common primary hepatic malignancy. Infitratinib is a...
Approved
Investigational
Matched Iupac: … 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-{[4-(4-ethylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)-1-methylurea …
Matched Description: … [A198963] Infitratinib is a pan-FGFR inhibitor, as it is an ATP-competitive inhibitor of all four FGFR ... granted accelerated approval to infigratinib - under the market name Truseltiq - for the treatment of …
Matched Salts cas: … 1310746-10-1 …
Matched Categories: … MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring ... Receptor, Fibroblast Growth Factor, Type 1, antagonists & inhibitors …
Matched Description: … [A198963] Infitratinib is a pan-FGFR inhibitor, as it is an ATP-competitive inhibitor of all four FGFR ... granted accelerated approval to infigratinib - under the market name Truseltiq - for the treatment of …
Matched Salts cas: … 1310746-10-1 …
Matched Categories: … MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring ... Receptor, Fibroblast Growth Factor, Type 1, antagonists & inhibitors …
Oteracil
Oteracil is an adjunct to antineoplastic therapy, used to reduce the toxic side effects associated with chemotherapy. Approved by the European Medicines Agency (EMA) in March 2011, Oteracil is available in combination with DB09257 and DB09256 within the commercially available product "Teysuno". The main active ingredient in Teysuno is DB09256,...
Approved
Matched Description: … By mimicking a class of compounds called "pyrimidines" that are essential components of RNA and DNA, ... The main active ingredient in Teysuno is [DB09256], a pro-drug of [DB00544] (5-FU), which is a cytotoxic ... Oteracil's main role within Teysuno is to reduce the activity of 5-FU within normal gastrointestinal …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Tivozanib
Renal cell carcinoma (RCC) is responsible for 3% of cancer cases and is one of the 10 most common cancers in adults. The average age of diagnosis is between age 65 to 74. Tivozanib, also known as FOTIVDA, is a kinase inhibitor developed to treat adult patients with relapsed or...
Approved
Investigational
Matched Iupac: … 1-{2-chloro-4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-3-(5-methyl-1,2-oxazol-3-yl)urea …
Matched Description: … Renal cell carcinoma (RCC) is responsible for 3% of cancer cases[A231314] and is one of the 10 most common ... The average age of diagnosis is between age 65 to 74. …
Matched Salts cas: … 682745-41-1 …
Matched Description: … Renal cell carcinoma (RCC) is responsible for 3% of cancer cases[A231314] and is one of the 10 most common ... The average age of diagnosis is between age 65 to 74. …
Matched Salts cas: … 682745-41-1 …
Doxorubicin
Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970.[A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a primary alcohol group compared to the methyl group of daunorubicin. Although its detailed...
Approved
Investigational
Matched Synonyms: … (1S,3S)-3-glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino ... -2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1- …
Matched Iupac: … )-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione ... (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-8-(2-hydroxyacetyl …
Matched Description: … [A1573,A257614,L45231] However, one of the major side effects of doxorubicin is cardiotoxicity, which ... Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius ... exert its effect through DNA intercalation, which eventually leads to DNA damage and the generation of …
Matched Products: … CAELYX 2 MG/ML KONSANTRE İNFUZYON ÇÖZELTİSİ, 1 ADET ... ADRIMISIN 10 MG LIYOFİLZİE ENJEKSİYONLUK TOZ ICEREN FLAKON, 1 ADET ... ADRIMISIN 50 MG LIYOFİLZİE ENJEKSİYONLUK TOZ ICEREN FLAKON, 1 ADET …
Matched Iupac: … )-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione ... (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-8-(2-hydroxyacetyl …
Matched Description: … [A1573,A257614,L45231] However, one of the major side effects of doxorubicin is cardiotoxicity, which ... Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius ... exert its effect through DNA intercalation, which eventually leads to DNA damage and the generation of …
Matched Products: … CAELYX 2 MG/ML KONSANTRE İNFUZYON ÇÖZELTİSİ, 1 ADET ... ADRIMISIN 10 MG LIYOFİLZİE ENJEKSİYONLUK TOZ ICEREN FLAKON, 1 ADET ... ADRIMISIN 50 MG LIYOFİLZİE ENJEKSİYONLUK TOZ ICEREN FLAKON, 1 ADET …
Urea C-14
Urea 14C is a urea molecule radiolabelled with a radioactive carbon-14. It is currently used for the Urea Breath Test (UBT) and is available as a rapid diagnostic test (marketed as PyTest) for the detection of Helicobacter pylori infections. H pylori is a common stomach bacteria that has been linked...
Approved
Matched Description: … As the urease enzyme is not present in mammalian cells, the presence of urease (and the products of urea ... Exhaled breath samples can then be collected and measured for the presence of radioactivity. ... Breath Test (UBT) and is available as a rapid diagnostic test (marketed as PyTest) for the detection of …
Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 4 individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). It is...
Approved
Investigational
Matched Synonyms: … Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine …
Matched Name: … Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … 4 individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from ... a sterile vaccine that contains saccharides of the capsular antigens of *Streptococcus pneumoniae* serotype ... cultures of *Corynebacterium diphtheriae* strain C7 (β197). …
Matched Mixtures name: … PREVENAR 0.5 ML ENJEKSIYON ICIN SUSPANSIYON ICEREN KULL.HAZ.ENJEKTOR, 1 ADET …
Matched Name: … Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … 4 individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from ... a sterile vaccine that contains saccharides of the capsular antigens of *Streptococcus pneumoniae* serotype ... cultures of *Corynebacterium diphtheriae* strain C7 (β197). …
Matched Mixtures name: … PREVENAR 0.5 ML ENJEKSIYON ICIN SUSPANSIYON ICEREN KULL.HAZ.ENJEKTOR, 1 ADET …
Pramipexole
Pramipexole is a drug used to treat the symptoms of Parkinson's Disease (PD). It is a non-ergot dopamine agonist drug that is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement) . It was first approved by the FDA in 1997 . Parkinson's Disease is...
Approved
Investigational
Matched Description: … Parkinson's Disease is one of the most common neurodegenerative disorders and causes a high level of ... Pramipexole is a drug used to treat the symptoms of Parkinson's Disease (PD). ... The prevalence of Parkinson's Disease worldwide has increased from approximately 2.5 million in 1990 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … SIFROL TABLET 1 mg ... PRANOW 1 MG TABLET, 30 ADET ... PARKIPEX 1 MG TABLET, 30 ADET …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … SIFROL TABLET 1 mg ... PRANOW 1 MG TABLET, 30 ADET ... PARKIPEX 1 MG TABLET, 30 ADET …
Trandolapril
Trandolapril is a non-sulhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to its biologically active diacid form, trandolaprilat, in the liver. Trandolaprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure...
Approved
Matched Iupac: … (2S,3aR,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-octahydro-1H-indole- …
Matched Description: … is a non-sulhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of ... ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... progression of renal disease in hypertensive individuals with diabetes mellitus and microalbuminuria …
Matched Mixtures name: … TARKA® SR240/4 TABLETAS. ... VERACOMB MR 240/4 MG KAPSÜL, 28 ADET ... TARKA FORTE 240/4 FILM TABLET, 28 ADET …
Matched Products: … GOPTEN FORTE 4 MG KAPSUL, 28 ADET …
Matched Description: … is a non-sulhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of ... ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... progression of renal disease in hypertensive individuals with diabetes mellitus and microalbuminuria …
Matched Mixtures name: … TARKA® SR240/4 TABLETAS. ... VERACOMB MR 240/4 MG KAPSÜL, 28 ADET ... TARKA FORTE 240/4 FILM TABLET, 28 ADET …
Matched Products: … GOPTEN FORTE 4 MG KAPSUL, 28 ADET …
Pholcodine
Pholcodine formula is 3-o-morpholinoethylmorphine and it is classified as an antitussive which is defined as an opioid cough suppressant. It belongs to the opioid family of compounds and it is widely used. Pholcodine activity is the suppression of unproductive cough and it also has a mild sedative effect with little...
Approved
Illicit
Matched Iupac: … (1S,5R,13R,14S,17R)-4-methyl-10-[2-(morpholin-4-yl)ethoxy]-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17 …
Matched Description: … It belongs to the opioid family of compounds and it is widely used. ... It is categorized as Class B drug in the UK and officially taken out of the shelves in 2008. ... [A31738] Pholcodine activity is the suppression of unproductive cough and it also has a mild sedative …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds with 4 or More Rings …
Matched Description: … It belongs to the opioid family of compounds and it is widely used. ... It is categorized as Class B drug in the UK and officially taken out of the shelves in 2008. ... [A31738] Pholcodine activity is the suppression of unproductive cough and it also has a mild sedative …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds with 4 or More Rings …
Osilodrostat
Osilodrostat is an inhibitor of 11β-hydroxylase (also referred to as CYP11B1), the enzyme that catalyzes the final step in the biosynthesis of endogenous cortisol. It is used to lower circulating cortisol levels in the treatment of Cushing's disease, a disorder in which cortisol levels are chronically and supraphysiologically elevated. Cushing's...
Approved
Investigational
Matched Iupac: … 3-fluoro-4-[(5R)-5H,6H,7H-pyrrolo[1,2-c]imidazol-5-yl]benzonitrile …
Matched Description: … resection of the tumour is generally the treatment of choice. ... the final step in the biosynthesis of endogenous cortisol. ... Osilodrostat is an inhibitor of 11β-hydroxylase (also referred to as CYP11B1), the enzyme that catalyzes …
Matched Categories: … MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring …
Matched Description: … resection of the tumour is generally the treatment of choice. ... the final step in the biosynthesis of endogenous cortisol. ... Osilodrostat is an inhibitor of 11β-hydroxylase (also referred to as CYP11B1), the enzyme that catalyzes …
Matched Categories: … MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring …
Phenazopyridine
Phenazopyridine, also known as Pyridium, is a urinary tract analgesic used for the short-term management of urinary tract irritation and its associated unpleasant symptoms such as burning and pain during urination. In the USA, this drug was previously marked by Roche but has been discontinued by the FDA. It is...
Approved
Matched Iupac: … 3-[(1E)-2-phenyldiazen-1-yl]pyridine-2,6-diamine …
Matched Description: … Ingestion of phenazopyridine is found to change the appearance of the urine by imparting an orange or ... [L7832] It is still used in various parts of the world. ... Phenazopyridine, also known as Pyridium, is a urinary tract analgesic used for the short-term management of …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Ingestion of phenazopyridine is found to change the appearance of the urine by imparting an orange or ... [L7832] It is still used in various parts of the world. ... Phenazopyridine, also known as Pyridium, is a urinary tract analgesic used for the short-term management of …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Berotralstat
Berotralstat is a selective inhibitor of plasma kallikrein used in the prophylaxis of attacks of hereditary angioedema (HAE). It works by blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated with attacks of HAE. Berotralstat is strictly used to...
Approved
Matched Synonyms: … (+)-1-(3-(aminomethyl) phenyl)-N-(5-((3-cyanophenyl)(cyclopropylmethylamino)methyl)-2-fluorophenyl)-3 ... (R)-1-(3-(aminomethyl) phenyl)-N-(5-((3- cyanophenyl)(cyclopropylmethylamino)methyl)-2-fluorophenyl)- …
Matched Iupac: … 1-[3-(aminomethyl)phenyl]-N-{5-[(R)-(3-cyanophenyl)[(cyclopropylmethyl)amino]methyl]-2-fluorophenyl}- …
Matched Description: … Berotralstat is a selective inhibitor of plasma kallikrein used in the prophylaxis of attacks of hereditary ... major biologic peptide that promotes swelling and pain associated with attacks of HAE. ... [L26661] It works by blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 1-[3-(aminomethyl)phenyl]-N-{5-[(R)-(3-cyanophenyl)[(cyclopropylmethyl)amino]methyl]-2-fluorophenyl}- …
Matched Description: … Berotralstat is a selective inhibitor of plasma kallikrein used in the prophylaxis of attacks of hereditary ... major biologic peptide that promotes swelling and pain associated with attacks of HAE. ... [L26661] It works by blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Quinidine
Quinidine is a D-isomer of quinine present in the bark of the Cinchona tree and similar plant species. This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication.[A38016,A250050] Quinidine is considered the first antiarrhythmic drug (class Ia) and is moderately efficacious in the acute...
Approved
Investigational
Matched Synonyms: … (S)-(6-Methoxy-quinolin-4-yl)-((2R,5R)-5-vinyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methanol ... α-(6-methoxy-4-quinolyl)-5-vinyl-2-quinuclidinemethanol ... 6-methoxy-α-(5-vinyl-2-quinuclidinyl)-4-quinolinemethanol …
Matched Iupac: … (S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methanol …
Matched Description: … Quinidine is a D-isomer of [quinine] present in the bark of the Cinchona tree and similar plant species ... [A38016] Due to its side effects and increased risk of mortality, the use of quinidine was reduced over ... considered the first antiarrhythmic drug (class Ia) and is moderately efficacious in the acute conversion of …
Matched Salts cas: … 1668-99-1 …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... Metabolic Side Effects of Drugs and Substances …
Matched Iupac: … (S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methanol …
Matched Description: … Quinidine is a D-isomer of [quinine] present in the bark of the Cinchona tree and similar plant species ... [A38016] Due to its side effects and increased risk of mortality, the use of quinidine was reduced over ... considered the first antiarrhythmic drug (class Ia) and is moderately efficacious in the acute conversion of …
Matched Salts cas: … 1668-99-1 …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... Metabolic Side Effects of Drugs and Substances …
Human calcitonin
Calcitonin was first discovered in isolated parathyroid tissue as a substance with a serum-calcium-lowering effect. It is constituted as a 32-amino acid single chain polypeptide structure that gets secreted as a regulatory agent in calcium-phosphorus metabolism. It is used as an alternative for people developing antibodies against salmon calcitonin.
Approved
Investigational
Cefditoren
Cefditoren is an oral third-generation cephalosporin. It is commonly marketed under the trade name Spectracef by Cornerstone BioPharma.
Approved
Investigational
Matched Iupac: … -5-yl)ethenyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-[(1Z)-2-(4-methyl-1,3-thiazol …
Matched Salts cas: … 117467-28-4 …
Matched Salts cas: … 117467-28-4 …
Nitrofurantoin
Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections.[L6856,L6859,L6862] Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. This drug is more resistant to the development of bacterial resistance because it acts...
Approved
Vet approved
Matched Synonyms: … 1-((5-nitrofurfurylidene)amino)hydantoin ... N-(5-Nitrofurfurylidene)-1-aminohydantoin ... 1-((5-nitro-2-furanyl)methylene)amino-2,4-imidazolidenedione …
Matched Iupac: … 1-[(E)-[(5-nitrofuran-2-yl)methylidene]amino]imidazolidine-2,4-dione …
Matched Description: … nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of ... [A179824] This drug is more resistant to the development of bacterial resistance because it acts on many …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 1-[(E)-[(5-nitrofuran-2-yl)methylidene]amino]imidazolidine-2,4-dione …
Matched Description: … nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of ... [A179824] This drug is more resistant to the development of bacterial resistance because it acts on many …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Tolfenamic acid
Tolfenamic acid, with the formula N-(2-methyl-3-chlorphenyl)-anthranilic acid, is a nonsteroidal anti-inflammatory agent. It was discovered by scientists at Medica Pharmaceutical Company in Finland. It is used in the UK as a treatment for migraine under the name of Clotam. In the US, it presents a Status class I by the...
Approved
Investigational
Matched Description: … By the European Medicine Agency, it was granted in 2016 with the status of orphan for the treatment of ... It is used in the UK as a treatment for migraine under the name of Clotam. …
Matched Products: … TOLCID 4% INJECTION ... TOLFEDINE 4% W/V SOLUTION FOR INJECTION FOR DOGS AND CATS …
Matched Products: … TOLCID 4% INJECTION ... TOLFEDINE 4% W/V SOLUTION FOR INJECTION FOR DOGS AND CATS …
Apalutamide
Apalutamide is a potent androgen receptor (AR) antagonist that selectively binds to the ligand-binding domain of AR and blocks AR nuclear translocation or binding to androgen response elements . It has been used in trials studying the treatment of Prostate Cancer, Hepatic Impairment, Prostatic Neoplasms, Castration-Resistant Prostate Cancer, and Prostatic...
Approved
Investigational
Matched Iupac: … 4-{7-[6-cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-sulfanylidene-5,7-diazaspiro[3.4]octan-5-yl}-2 …
Matched Description: … show no evidence of cancer metastasis at the time of castration-resistant diagnosis [L1295]. ... Approximately 10 to 20 % of prostate cancer cases are castration-resistant, and up to 16% of these patients ... prostate cancer had ≥50% PSA decline at week 12 of apalutamide treatment [A31846]. …
Matched Categories: … MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring …
Matched Description: … show no evidence of cancer metastasis at the time of castration-resistant diagnosis [L1295]. ... Approximately 10 to 20 % of prostate cancer cases are castration-resistant, and up to 16% of these patients ... prostate cancer had ≥50% PSA decline at week 12 of apalutamide treatment [A31846]. …
Matched Categories: … MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring …
Bioallethrin
Bioallethrin refers to a mixture of two of the allethrin isomers (1R,trans;1R and 1R,trans;1S) in an approximate ratio of 1:1, where both isomers are active ingredients. A mixture of the two same stereoisomers, but in an approximate ratio of R:S in 1:3, is called esbiothrin. A mixture containing only S-forms...
Approved
Experimental
Matched Iupac: … 2-methyl-4-oxo-3-(prop-2-en-1-yl)cyclopent-2-en-1-yl 2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane ... -1-carboxylate …
Matched Description: … approximate ratio of 1:1, where both isomers are active ingredients. ... A mixture of the two same stereoisomers, but in an approximate ratio of R:S in 1:3, is called esbiothrin ... Bioallethrin refers to a mixture of two of the allethrin isomers (1R,trans;1R and 1R,trans;1S) in an …
Matched Description: … approximate ratio of 1:1, where both isomers are active ingredients. ... A mixture of the two same stereoisomers, but in an approximate ratio of R:S in 1:3, is called esbiothrin ... Bioallethrin refers to a mixture of two of the allethrin isomers (1R,trans;1R and 1R,trans;1S) in an …
Teicoplanin
Teicoplanin is a glycopeptide antibiotic consisting of a mixture of several compounds, five major (named teicoplanin A2-1 through A2-5) and four minor (named teicoplanin RS-1 through RS-4). All teicoplanins share a same glycopeptide core, teicoplanin A3-1, but differ in the length and conformation of side chains attached to their β-D-glucosamine...
Approved
Investigational
Matched Iupac: … {8,12}.1^{23,27}.1^{29,33}.1^{41,45}.0^{10,37}.0^{46,51}]hexahexaconta-3,5,8(64),9,11,14,16,23,25,27( ... oxan-2-yl]oxy}-7,13,28-trioxa-20,36,39,53,55,58-hexaazaundecacyclo[38.14.2.2^{3,6}.2^{14,17}.2^{19,34}.1^ …
Matched Description: … teicoplanin A2-1 through A2-5) and four minor (named teicoplanin RS-1 through RS-4). ... Teicoplanin is a glycopeptide antibiotic consisting of a mixture of several compounds, five major (named ... of side chains attached to their β-D-glucosamine moiety. …
Matched Products: … ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 FLAKON VE 1 AMPUL ... ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 FLAKON VE 1 AMPUL ... ENJEKSIYONLUK ÇÖZELTI IÇIN LIYOFILIZE TOZ IÇEREN FLAKON, 1 FLAKON + 1 AMPUL …
Matched Description: … teicoplanin A2-1 through A2-5) and four minor (named teicoplanin RS-1 through RS-4). ... Teicoplanin is a glycopeptide antibiotic consisting of a mixture of several compounds, five major (named ... of side chains attached to their β-D-glucosamine moiety. …
Matched Products: … ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 FLAKON VE 1 AMPUL ... ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 FLAKON VE 1 AMPUL ... ENJEKSIYONLUK ÇÖZELTI IÇIN LIYOFILIZE TOZ IÇEREN FLAKON, 1 FLAKON + 1 AMPUL …
Pitolisant
Pitolisant is a selective antagonist or inverse agonist of the histamine H3 receptor used to treat type 1 or 2 narcolepsy. Narcolepsy is a chronic neurological disorder that affects 1 in 2,000 individuals and is characterized by excessive daytime sleepiness, abnormal REM sleep manifestations, sleep paralysis and hypnagogic hallucinations. About...
Approved
Investigational
Matched Iupac: … 1-{3-[3-(4-chlorophenyl)propoxy]propyl}piperidine …
Matched Description: … 1 or 2 narcolepsy. ... [L8063] Narcolepsy is a chronic neurological disorder that affects 1 in 2,000 individuals and is characterized ... [A32024] The therapeutic effectiveness of pitolisant was comparable to that of [modafinil]. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … 1 or 2 narcolepsy. ... [L8063] Narcolepsy is a chronic neurological disorder that affects 1 in 2,000 individuals and is characterized ... [A32024] The therapeutic effectiveness of pitolisant was comparable to that of [modafinil]. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 451 - 475 of 12592 in total