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Displaying drugs 26 - 50 of 82 in total
Isosorbide
Isosorbide was previously available in an oral formulation for the reduction of intraocular pressure. It was approved by the FDA in 1980, but has since been discontinued. Currently, isosorbide is an organic nitrate currently available in the isosorbide mononitrate and isosorbide dinitrate forms, and is used for the prevention of...
Approved
Investigational
Matched Description: … Currently, isosorbide is an organic nitrate currently available in the [isosorbide mononitrate] and [ …
Isoconazole
Isoconazole is an azole antifungal drug that has similar effectiveness to clotrimazole in the treatment of foot and vaginal infections.
Approved
Matched Salts name: … Isoconazole nitrate …
Metronidazole
Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis, and amebiasis which are parasitic infections.[A181036,A181039] Metronidazole has been used as an antibiotic for several decades , with added antiparasitic properties that set...
Approved
Matched Mixtures name: … TRIMIC (Metronidazole & Miconazole Nitrate Vaginal Suppositories) …
Chromium gluconate
Approved
Chromous sulfate
Approved
Sapropterin
Sapropterin (tetrahydrobiopterin or BH4) is a cofactor in the synthesis of nitric oxide. It is also essential in the conversion of phenylalanine to tyrosine by the enzyme phenylalanine-4-hydroxylase; the conversion of tyrosine to L-dopa by the enzyme tyrosine hydroxylase; and conversion of tryptophan to 5-hydroxytryptophan via tryptophan hydroxylase.
Approved
Investigational
Silver
Silver (Ag) is a chemical element that belongs in the family of transition metals in the periodic table. It has a high electrical conductivity, thermal conductivity, and reflectivity. Silver exists as a pure elemental form, alloy with other metals, and mineral. Having critical roles in various applications inducing chemical and...
Approved
Investigational
Zinc sulfate
Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol". It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
Approved
Investigational
Matched Salts name: … Zinc sulfate hexahydrate …
Thiamine
Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays...
Approved
Investigational
Nutraceutical
Vet approved
Nicotinamide
An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
Approved
Investigational
Matched Mixtures name: … Econazole Nitrate 1% / Niacinamide 4% ... 071023 Econazole Nitrate 1% / Niacinamide 4% …
Bismuth subnitrate
Bismuth subnitrate, also referred to as bismuth oxynitrate or bismuthyl nitrate, is a highly water-soluble crystalline compound that has been used as a treatment for duodenal ulcers and anti-diarrheic agent . The use of bismuth substrate as an active ingredient in over-the-counter antacids is approved by the FDA.
Approved
Matched Synonyms: … Bismuth nitrate, basic ... Bismuth hydroxide nitrate oxide …
Matched Description: … Bismuth subnitrate, also referred to as bismuth oxynitrate or bismuthyl nitrate, is a highly water-soluble …
Matched Description: … Bismuth subnitrate, also referred to as bismuth oxynitrate or bismuthyl nitrate, is a highly water-soluble …
Nitroglycerin
Nitroglycerin, also known as glyceryl trinitrate, is an organic nitrate and a vasodilating agent that was first discovered in 1847. Originally used to dynamite, its antianginal effects were identified in the late 1860s after it produced headaches in factory workers while workers with angina pectoris or heart failure experienced relief...
Approved
Investigational
Matched Synonyms: … 1,2,3-propanetriyl nitrate …
Matched Iupac: … 1,3-bis(nitrooxy)propan-2-yl nitrate …
Matched Description: … Nitroglycerin, also known as glyceryl trinitrate,[A180169] is an organic nitrate and a vasodilating agent …
Matched Categories: … Nitrate Vasodilator …
Matched Iupac: … 1,3-bis(nitrooxy)propan-2-yl nitrate …
Matched Description: … Nitroglycerin, also known as glyceryl trinitrate,[A180169] is an organic nitrate and a vasodilating agent …
Matched Categories: … Nitrate Vasodilator …
Isosorbide mononitrate
Isosorbide mononitrate is an organic nitrate with vasodilating properties. It is an anti-anginal agent that works by relaxing the smooth muscles of both arteries and veins, but but predominantly veins to reduce cardiac preload.[L11698, L11743] Isosorbide mononitrate is an active metabolite of isosorbide dinitrate. Like other organic nitrates, isosorbide mononitrate...
Approved
Matched Synonyms: … Isosorbide 5-nitrate …
Matched Iupac: … (3R,3aS,6S,6aR)-6-hydroxy-hexahydrofuro[3,2-b]furan-3-yl nitrate …
Matched Description: … Isosorbide mononitrate is an organic nitrate with vasodilating properties. …
Matched Categories: … Nitrate Vasodilator …
Matched Iupac: … (3R,3aS,6S,6aR)-6-hydroxy-hexahydrofuro[3,2-b]furan-3-yl nitrate …
Matched Description: … Isosorbide mononitrate is an organic nitrate with vasodilating properties. …
Matched Categories: … Nitrate Vasodilator …
Econazole
A broad spectrum antimycotic with some action against Gram positive bacteria. It is used topically in dermatomycoses also orally and parenterally.
Approved
Matched Mixtures name: … Econazole Nitrate 1% / Niacinamide 4% ... 071023 Econazole Nitrate 1% / Niacinamide 4% …
Matched Salts name: … Econazole nitrate …
Matched Products: … Econazole Nitrate ... Econazole Nitrate Cream ... Econazole Nitrate Topical Foam, 1% …
Matched Salts name: … Econazole nitrate …
Matched Products: … Econazole Nitrate ... Econazole Nitrate Cream ... Econazole Nitrate Topical Foam, 1% …
Oxiconazole
Oxiconazole is an antifungal agent that is commonly found in topical formulations. It is marketed under the brand names Oxistat and Oxistat, and is used in the treatment of various skin infections such as athlete's foot, jock itch and ringworm.
Approved
Matched Salts name: … Oxiconazole nitrate …
Matched Products: … Oxiconazole Nitrate ... Oxiconazole Nitrate Cream 1% …
Matched Products: … Oxiconazole Nitrate ... Oxiconazole Nitrate Cream 1% …
Nickel sulfate
Nickel sulfate is used in allergenic testing.
Approved
Experimental
Matched Salts name: … Nickel sulfate hexahydrate …
Pentaerythritol tetranitrate
Pentaerythritol tetranitrate is the nitrate ester of pentaerythritol that possesses explosive properties. When mixed with a plasticizer, this chemical forms a plastic explosive. It is recognized by the FDA to be a coronary vasodilator in the treatment of heart conditions such as angina .
It is a pentaerythritol nitrate in...
Approved
Matched Iupac: … 3-(nitrooxy)-2,2-bis[(nitrooxy)methyl]propyl nitrate …
Matched Description: … to the corresponding nitrate ester. ... Pentaerythritol tetranitrate is the nitrate ester of pentaerythritol that possesses explosive properties ... It is a pentaerythritol nitrate in which all four hydroxy groups of pentaerythritol have been converted …
Matched Description: … to the corresponding nitrate ester. ... Pentaerythritol tetranitrate is the nitrate ester of pentaerythritol that possesses explosive properties ... It is a pentaerythritol nitrate in which all four hydroxy groups of pentaerythritol have been converted …
Butoconazole
Butoconazole is an imidazole antifungal used in gynecology.
Approved
Matched Salts name: … Butoconazole nitrate …
Dipyridamole
A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
Approved
Fostamatinib
Fostamatinib has been investigated for the treatment and basic science of Rheumatoid Arthritis and Immune Thrombocytopenic Purpura (ITP). It was approved on April 17, 2018, under the trade name Tavalisse for use in ITP [L2644, FDA Label]. Fostamatinib has also been granted orphan drug status by the FDA .
Recently,...
Approved
Investigational
Chromic chloride
Chromic chloride, for injection, is a sterile, nonpyrogenic solution intended for use as an additive to solutions for Total Parenteral Nutrition (TPN).
Approved
Matched Salts name: … Chromic chloride hexahydrate …
Nitrous acid
Nitrous acid (as sodium nitrite) is used as part of an intravenous mixture with sodium thiosulfate to treat cyanide poisoning. It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system. There is also research to investigate...
Approved
Investigational
Nitric Oxide
Nitric oxide or Nitrogen monoxide is a chemical compound with chemical formula NO. This gas is an important signaling molecule in the body of mammals including humans and is an extremely important intermediate in the chemical industry. It is also a toxic air pollutant produced by automobile engines and power...
Approved
Berdazimer
Berdazimer is a polymeric substance consisting of a polysiloxane backbone (Si-O-Si bonds) with covalently bound N-diazeniumdiolate nitric oxide (NO) donors. It releases NO through exposure to proton donors like water, which will degrade the N-diazeniumdiolate entity. Berdazimer was previously investigated as a potential treatment for molluscum contagiosum, a viral cutaneous...
Approved
Displaying drugs 26 - 50 of 82 in total