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Displaying drugs 476 - 500 of 2573 in total
Iptacopan
Iptacopan is a small-molecule factor B inhibitor previously investigated as a potential treatment for the rare blood disease paroxysmal nocturnal hemoglobinuria (PNH) by inhibiting the complement factor B. Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and subsequently C5 convertase. This is...
Approved
Investigational
Matched Synonyms: … 4-((2S,4S)-4-ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl) benzoic acid ... BENZOIC ACID, 4-((2S,4S)-4-ETHOXY-1-((5-METHOXY-7-METHYL-1H-INDOL-4-YL)METHYL)-2-PIPERIDINYL)- …
Matched Iupac: … 4-[(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl]benzoic acid …
Matched Description: … Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and ... the glycosyl phosphatidylinositol–anchored proteins that normally anchor 2 membrane proteins, CD55 and ... , where 82.3% and 77.5% of patients experienced a sustained hemoglobin improvement without transfusions …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 4-[(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl]benzoic acid …
Matched Description: … Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and ... the glycosyl phosphatidylinositol–anchored proteins that normally anchor 2 membrane proteins, CD55 and ... , where 82.3% and 77.5% of patients experienced a sustained hemoglobin improvement without transfusions …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Trazpiroben
Investigational
Matched Synonyms: … (3-((1-cyclohexyl-4-oxo-8-(4-oxo-4-phenylbutyl)-1,3,8 triazaspiro(4.5) decan-3-yl)methyl)benzoic acid ... Benzoic acid, 3-((1-cyclohexyl-4-oxo-8-(4-oxo-4-phenylbutyl)-1,3,8-triazaspiro(4.5)dec-3-yl)methyl)- …
Lormetazepam
Lormatazepam is an orally available benzodiazepine used in the UK for the treatment of short-term insomnia . It is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations.
Approved
Matched Description: … It is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations. …
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepines and benzodiazepine derivatives …
Matched Products: … LORMETAZEPAM ACIS 0.5MG ... LORMETAZEPAM ACIS 1.0MG ... LORMETAZEPAM ACIS 2.0MG …
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepines and benzodiazepine derivatives …
Matched Products: … LORMETAZEPAM ACIS 0.5MG ... LORMETAZEPAM ACIS 1.0MG ... LORMETAZEPAM ACIS 2.0MG …
Sulfamoxole
Sulfamoxole is an antibacterial in the sulfonamide class.
Experimental
Matched International brands: … Sulfuno …
Matched Categories: … Sulfur Compounds ... sulfamoxole and trimethoprim ... Sulfonamides and trimethoprim …
Matched Categories: … Sulfur Compounds ... sulfamoxole and trimethoprim ... Sulfonamides and trimethoprim …
N-Benzyl-3-(alpha-D-galactopyranosyloxy)benzamide
Experimental
Matched Synonyms: … N-Benzyl-3-(α-D-galactopyranosyloxy)benzamide …
Matched Name: … N-Benzyl-3-(alpha-D-galactopyranosyloxy)benzamide …
Matched Iupac: … N-benzyl-3-{[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}benzamide …
Matched Name: … N-Benzyl-3-(alpha-D-galactopyranosyloxy)benzamide …
Matched Iupac: … N-benzyl-3-{[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}benzamide …
Etafedrine
Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has been an ingredient combined with other drugs in the brand names Nethaprin and Dalmacol . It was previously available as both the free base and as the hydrochloride salt manufactured by Sanofi-Aventis (now Sanofi) has been discontinued .
Ethylephedrine is...
Approved
Matched Synonyms: … alpha-(1-(ethylmethylamino)ethyl)benzyl alcohol …
Matched Description: … with other drugs in the brand names Nethaprin [A32757] and Dalmacol [L2568]. ... Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has been an ingredient combined ... It was previously available as both the free base and as the hydrochloride salt manufactured by Sanofi-Aventis …
Matched Description: … with other drugs in the brand names Nethaprin [A32757] and Dalmacol [L2568]. ... Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has been an ingredient combined ... It was previously available as both the free base and as the hydrochloride salt manufactured by Sanofi-Aventis …
Benzoylecgonine
Benzoylecgonine is the major metabolite of cocaine. It is formed by hydrolysis of cocaine in the liver, catalysed by carboxylesterases. It is excreted in the urine of cocaine users after processing in the liver. It is the main pharmaceutical ingredient in the investigational drug Esterom, a topical solution used for...
Experimental
Illicit
Matched Synonyms: … O-benzoyl-(-)-ecgonine ... 3-(Benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid ... (1R,2R,3S,5S)-8-methyl-3-[(phenylcarbonyl)oxy]-8-azabicyclo[3.2.1]octane-2-carboxylic acid …
Matched Iupac: … (1R,2R,3S,5S)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid …
Matched Iupac: … (1R,2R,3S,5S)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid …
Triphosphoric acid
Used as water softener, peptizing agent, emulsifier & dispersing agent; ingredient of cleansers; meat preservative.
Experimental
Matched Synonyms: … acide triphosphorique ... tripolyphosphoric acid ... catena-triphosphoric acid …
Matched Name: … Triphosphoric acid …
Matched Iupac: … {[hydroxy(phosphonooxy)phosphoryl]oxy}phosphonic acid …
Matched Categories: … Acids ... Phosphoric Acids ... Phosphorus Acids ... Acids, Noncarboxylic …
Matched Name: … Triphosphoric acid …
Matched Iupac: … {[hydroxy(phosphonooxy)phosphoryl]oxy}phosphonic acid …
Matched Categories: … Acids ... Phosphoric Acids ... Phosphorus Acids ... Acids, Noncarboxylic …
Celivarone
Celivarone is under investigation in clinical trial NCT00233441 (Placebo Controlled Double-blind Dose Ranging Study of the Efficacy and Safety of SSR149744C 50, 100, 200 or 300 Mg OD With Amiodarone as Calibrator for the Maintenance of Sinus Rhythm in Patients With Recent Atrial Fibrillation/flutter).
Investigational
Matched Synonyms: … Isopropyl 2-butyl-3-(4-(3-(dibutylamino)propyl)benzoyl)-1-benzofuran-5-carboxylate …
Matched Iupac: … propan-2-yl 2-butyl-3-{4-[3-(dibutylamino)propyl]benzoyl}-1-benzofuran-5-carboxylate …
Matched Description: … investigation in clinical trial NCT00233441 (Placebo Controlled Double-blind Dose Ranging Study of the Efficacy and …
Matched Iupac: … propan-2-yl 2-butyl-3-{4-[3-(dibutylamino)propyl]benzoyl}-1-benzofuran-5-carboxylate …
Matched Description: … investigation in clinical trial NCT00233441 (Placebo Controlled Double-blind Dose Ranging Study of the Efficacy and …
Benzyl formate
Experimental
Matched Name: … Benzyl formate …
Matched Iupac: … benzyl formate …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Matched Iupac: … benzyl formate …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Olopatadine
Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions. It is a structural analog of doxepin, which has a minimal anti-allergic activity. Olopatadine works by blocking the effects of histamine, which is a primary inflammatory mediator that causes inflammatory and...
Approved
Matched Iupac: … dimethylamino)propylidene]-9-oxatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaen-5-yl]acetic acid …
Matched Description: … seasonal and perennial allergic conjunctivitis in 1996 and 2002, respectively. ... inflammatory and allergic reactions. ... Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Eye Allergy Itch and Redness Relief ... Eye Allergy Itch and Redness Relief Twice Daily Relief …
Matched Description: … seasonal and perennial allergic conjunctivitis in 1996 and 2002, respectively. ... inflammatory and allergic reactions. ... Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Eye Allergy Itch and Redness Relief ... Eye Allergy Itch and Redness Relief Twice Daily Relief …
Phenazopyridine
Phenazopyridine, also known as Pyridium, is a urinary tract analgesic used for the short-term management of urinary tract irritation and its associated unpleasant symptoms such as burning and pain during urination. In the USA, this drug was previously marked by Roche but has been discontinued by the FDA. It is...
Approved
Matched Description: … its associated unpleasant symptoms such as burning and pain during urination. ... Pyridium, is a urinary tract analgesic used for the short-term management of urinary tract irritation and …
Matched Mixtures name: … Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and Butabarbital …
Matched Categories: … Antipruritics and Local Anesthetics ... Genito Urinary System and Sex Hormones …
Matched Products: … Foster and Thrive Maximum Strength Urinary Pain Relief ... Foster and Thrive Neighbor Pharmacy Urinary Pain Relief …
Matched Mixtures name: … Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and Butabarbital …
Matched Categories: … Antipruritics and Local Anesthetics ... Genito Urinary System and Sex Hormones …
Matched Products: … Foster and Thrive Maximum Strength Urinary Pain Relief ... Foster and Thrive Neighbor Pharmacy Urinary Pain Relief …
Benzoin
Benzoin is a white crystalline compound prepared by condensation of benzaldehyde in potassium cyanide, and is used in organic syntheses. This should not be confused with benzoin gum from STYRAX (see DB11222). Benzoin is an FDA-approved colour additive used for marking fruits and vegetables.
Approved
Experimental
Matched Synonyms: … (+-)-Benzoin ... Benzoin extract (resinoid) …
Matched Name: … Benzoin …
Matched Description: … Benzoin is an FDA-approved colour additive used for marking fruits and vegetables. ... , and is used in organic syntheses. ... This should not be confused with benzoin gum from STYRAX (see [DB11222]). …
Matched Name: … Benzoin …
Matched Description: … Benzoin is an FDA-approved colour additive used for marking fruits and vegetables. ... , and is used in organic syntheses. ... This should not be confused with benzoin gum from STYRAX (see [DB11222]). …
5-Benzylacyclouridine
Experimental
Matched Synonyms: … 5-benzyl-1-(2-hydroxyethoxymethyl)uracil …
Matched Iupac: … 5-benzyl-1-[(2-hydroxyethoxy)methyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Iupac: … 5-benzyl-1-[(2-hydroxyethoxy)methyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Selenium
Selenium is a trace metal in the human body particularly important as a component of glutathione peroxidase, an important enzyme in the prevention of cellular damage by free radicals and reactive oxygen species [FDA Label]
Approved
Investigational
Vet approved
Matched Description: … , an important enzyme in the prevention of cellular damage by free radicals and reactive oxygen species ... Selenium is a trace metal in the human body particularly important as a component of glutathione peroxidase …
Matched Mixtures name: … Henkel's Vitamin E and Selenium Cap ... Multiple Vitamins and Minerals ... Maxine Vitamin and Mineral Supplement …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Products: … Selenious Acid …
Matched Mixtures name: … Henkel's Vitamin E and Selenium Cap ... Multiple Vitamins and Minerals ... Maxine Vitamin and Mineral Supplement …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Products: … Selenious Acid …
Clesacostat
Clesacostat is under investigation in clinical trial NCT04321031 (Metabolic Interventions to Resolve Non-alcoholic Steatohepatitis (NASH) With Fibrosis (MIRNA)).
Investigational
Matched Synonyms: … Benzoic acid, 4-(6-methoxy-4-((1,4,6,7-tetrahydro-1-(1-methylethyl)-7-oxospiro(5h-indazole-5,4'-piperidin ... acid ... -(7-oxo-1-(propan-2-yl)-1,4,6,7-tetrahydrospiro(indazole-5,4'- piperidine)-1'-carbonyl)pyridin-2-yl)benzoic …
Terbutaline
Terbutaline was first synthesized in 1966 and described in the literature in the late 1960s and early 1970s. It is a selective beta-2 adrenergic agonist used as a bronchodilator in asthmatic patients.[A230333,L32093,L32098]
Terbutaline was granted FDA approval on 25 March 1974.
Approved
Matched Description: … and early 1970s. ... Terbutaline was first synthesized in 1966[A230333] and described in the literature in the late 1960s …
Matched Products: … SULTER 2.5 MG ... SULTER SOLUCION …
Matched Products: … SULTER 2.5 MG ... SULTER SOLUCION …
Tolazoline
A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn.
Approved
Vet approved
Matched Synonyms: … 2-Benzyl-2-imidazoline ... 2-Benzyl-4,5-imidazoline …
Matched Iupac: … 2-benzyl-4,5-dihydro-1H-imidazole …
Matched Description: … A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. ... Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the …
Matched Categories: … Topical Products for Joint and Muscular Pain …
Matched Iupac: … 2-benzyl-4,5-dihydro-1H-imidazole …
Matched Description: … A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. ... Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the …
Matched Categories: … Topical Products for Joint and Muscular Pain …
Neomycin
Neomycin is a broad-spectrum aminoglycoside antibiotic drug that is derived from the metabolic products of Streptomyces fradiae. Neomycin is a complex comprised of three components, neomycin A, B, and C. Neomycin B, also known as framycetin, is the most active component of the complex and neomycin C is the isomer...
Approved
Vet approved
Matched Description: … [A175042] Neomycin is active against both gram-positive and gram-negative organisms and mediates its ... [L11979] Neomycin is a complex comprised of three components, neomycin A, B, and C. ... preparations for use in the treatment of inflammatory conditions and infections in the eye. …
Matched Mixtures name: … Neomycin and Polymyxin B Sulfates and Bacitracin Zinc ... Neomycin and Polymyxin B Sulfates and Hydrocortisone ... Neomycin and Polymyxin B Sulfates and Dexamethasone …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Ophthalmological and Otological Preparations ... Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Products: … Pomada de Sulfa ... Pomada Sulfa First Aid Antibiotic …
Matched Mixtures name: … Neomycin and Polymyxin B Sulfates and Bacitracin Zinc ... Neomycin and Polymyxin B Sulfates and Hydrocortisone ... Neomycin and Polymyxin B Sulfates and Dexamethasone …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Ophthalmological and Otological Preparations ... Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Products: … Pomada de Sulfa ... Pomada Sulfa First Aid Antibiotic …
Panthenol
Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Panthenol exists as a racemic mixture containing both the dextrorotatory form (dexpanthenol) and the levorotatory form (levopanthenol). While pantothenic acid is optically active, only the dextrorotatory...
Approved
Matched Description: … Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an ... Panthenol exists as a racemic mixture containing both the dextrorotatory form (dexpanthenol) and the ... While pantothenic acid is optically active, only the dextrorotatory form ([DB09357]) is biologically …
Matched Mixtures name: … Therapytion Nokmosu Neutral and oily Hair ... Therapytion Nokmosu Sensitive and Dry Hair …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Matched Products: … BABOR Baborganic Calm and Relax …
Matched Mixtures name: … Therapytion Nokmosu Neutral and oily Hair ... Therapytion Nokmosu Sensitive and Dry Hair …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Matched Products: … BABOR Baborganic Calm and Relax …
Tideglusib
Tideglusib is under the investigation for the development of treatments for Alzheimer's disease and for progressive supranuclear palsy. It is reported to be a potent anti-inflammatory and neuroprotective that is a non-ATP competitive inhibitor of glycogen synthase kinase 3 (GSK-3). Tideglusib is being developed by the Spanish pharmaceutic company Zeltia...
Investigational
Withdrawn
Matched Synonyms: … 4-BENZYL-2-(A-NAPHTYL)-1,2,4-THIADIAZOLIDINE-3,5-DIONE ... 4-Benzyl-2-(naphthalen-1-yl)-1,2,4-thiadiazolidine-3,5-dione …
Matched Iupac: … 4-benzyl-2-(naphthalen-1-yl)-1,2,4-thiadiazolidine-3,5-dione …
Matched Description: … Tideglusib is under the investigation for the development of treatments for Alzheimer's disease and for ... It is reported to be a potent anti-inflammatory and neuroprotective that is a non-ATP competitive inhibitor ... [A31601] Tideglusib is being developed by the Spanish pharmaceutic company Zeltia group and its current …
Matched Categories: … Sulfur Compounds …
Matched Iupac: … 4-benzyl-2-(naphthalen-1-yl)-1,2,4-thiadiazolidine-3,5-dione …
Matched Description: … Tideglusib is under the investigation for the development of treatments for Alzheimer's disease and for ... It is reported to be a potent anti-inflammatory and neuroprotective that is a non-ATP competitive inhibitor ... [A31601] Tideglusib is being developed by the Spanish pharmaceutic company Zeltia group and its current …
Matched Categories: … Sulfur Compounds …
Levomenthol
Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. Forming clear or white waxy, crystalline substance, menthol is typically solid at room temperature. (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration. Menthol mediates anesthetic properties and...
Approved
Matched Description: … . (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration ... Menthol mediates anesthetic properties and anti-irritating properties locally, thus it is widely used …
Matched Mixtures name: … BENCODYL LINCTUS ... Pediatric Bencodyl Linctus ... Jack and Jill Rub …
Matched Categories: … Basic Lotions and Liniments ... Herbs and Natural Products ... Antipruritics and Local Anesthetics ... Other Cold and Cough Preparations …
Matched Products: … Musle and Joint ... Performance and Recovery …
Matched Mixtures name: … BENCODYL LINCTUS ... Pediatric Bencodyl Linctus ... Jack and Jill Rub …
Matched Categories: … Basic Lotions and Liniments ... Herbs and Natural Products ... Antipruritics and Local Anesthetics ... Other Cold and Cough Preparations …
Matched Products: … Musle and Joint ... Performance and Recovery …
Pyrophosphoric acid
Approved
Experimental
Matched Synonyms: … Diphosphoric acid ... acide diphosphorique …
Matched Name: … Pyrophosphoric acid …
Matched Iupac: … (phosphonooxy)phosphonic acid …
Matched Categories: … Acids ... Phosphoric Acids ... Phosphorus Acids ... Acids, Noncarboxylic …
Matched Name: … Pyrophosphoric acid …
Matched Iupac: … (phosphonooxy)phosphonic acid …
Matched Categories: … Acids ... Phosphoric Acids ... Phosphorus Acids ... Acids, Noncarboxylic …
Orvacabtagene autoleucel
Investigational
Matched Synonyms: … CD4+ CD8+ T CELLS ARE DERIVED FROM ISOLATED BLOOD OF THE PATIENT AND ARE TRANSDUCED WITH NON-REPLICATIVE …
Relmacabtagene autoleucel
Investigational
Matched Synonyms: … AUTOLOGOUS CD4+ AND CD8+ T CELLS, ENRICHED FROM PERIPHERAL BLOOD MONONUCLEAR CELLS (PBMCS) TRANSDUCED …
Displaying drugs 476 - 500 of 2573 in total