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Displaying drugs 601 - 625 of 10948 in total

Ethionamide

A second-line antitubercular agent that inhibits mycolic acid synthesis. It also may be used for treatment of leprosy. (From Smith and Reynard, Textbook of Pharmacology, 1992, p868)
Approved
Matched Description: … It also may be used for treatment of leprosy. ... (From Smith and Reynard, Textbook of Pharmacology, 1992, p868) …
Matched Categories: … Drugs for Treatment of Tuberculosis …

Methoxyphenamine

Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Pivmecillinam

Pivmecillinam is a mecillinam prodrug, a pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa. It is active against gram-negative organisms and used as for amdinocillin. [PubChem]
Approved
Matched Iupac: … [(2S,5R,6R)-6-{[(azepan-1-yl)methylidene]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane- …
Matched Description: … orally, but broken down to amdinocillin in the intestinal mucosa. ... Pivmecillinam is a mecillinam prodrug, a pivaloyloxymethyl ester of amdinocillin that is well absorbed …
Matched Categories: … combinations of penicillins …

Tragacanth

Tragacanth allergenic extract is used in allergenic testing.
Approved
Matched Description: … Tragacanth allergenic extract is used in allergenic testing. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Alginic acid

Alginic acid, also referred to as algin or alginate, is a hydrophilic or anionic polysaccharide isolated from certain brown seaweed (Phacophycae) via alkaline extraction. It is present in cell walls of brown algae where it forms a viscous gel when binding with water. Alginic acid is a linear polymer consisted...
Approved
Investigational
Matched Description: … Available in different types of salt, alginic acid has been used in a variety of uses in food, cosmetics ... It is present in cell walls of brown algae where it forms a viscous gel when binding with water. ... gastroesophageal reflux by creating a physical barrier in presence of gastric acid [F46]. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Pyridoxine

Pyridoxine is the 4-methanol form of vitamin B6, an important water-soluble vitamin that is naturally present in many foods. As its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required for normal functioning of many biological systems within the body. While many plants and microorganisms are...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … treatment of nausea and vomiting in pregnancy. ... of pyridoxine in the above-mentioned metabolic functions). ... in a wide range of biochemical reactions, including the metabolism of amino acids and glycogen, the synthesis …
Matched Mixtures name: … Mega 13 Multivitamin Formula ... Harvest Of Values All B Complex Tab ... Herbs of Gold B Complex Plus Softgel …
Matched Categories: … Drugs for Treatment of Tuberculosis …

Levocarnitine

Constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.
Approved
Investigational
Matched Description: … It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias ... Constituent of striated muscle and liver. …

Influenza A virus A/North carolina/04/2016 (H3N2) hemagglutinin antigen (MDCK cell derived, propiolactone inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …

Levomilnacipran

Levomilnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI), although it is a more potent inhibitor of norepinephrine reuptake than serotonin reuptake.[A261181, A38560] Levomilnacipran is the more active 1S,2R-enantiomer in the racemate milnacipran.[A261181, L47956] Once administered, interconversion between levomilnacipran and its stereoisomer does not occur in humans. First approved...
Approved
Investigational
Matched Description: … selective serotonin and norepinephrine reuptake inhibitor (SNRI), although it is a more potent inhibitor of ... [A261181, A38560] Levomilnacipran is the more active 1S,2R-enantiomer in the racemate [milnacipran]. ... While levomilnacipran was previously investigated and proposed as a potential treatment for stroke in …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Tioconazole

Tioconazole is an imidazole antifungal used to treat fungal and yeast infections. Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus". Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. In...
Approved
Matched Description: … demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of ... In this way, tioconazole inhibits ergosterol synthesis, resulting in increased cellular permeability. ... In addition to being an antifungal, tioconazole also has antibacterial effects on certain Gram-positive …
Matched Salts cas: … 61675-64-7 …
Matched Mixtures name: … GYNOMAX L VAJINAL OVUL, 7 ADET ... GYNOMAX 100 MG/150 MG VAJINAL OVUL, 7 ADET …
Matched Categories: … combinations of imidazole derivatives ... Metabolic Side Effects of Drugs and Substances …

Rose bengal

Rose bengal is a pink stain derived as an analogue of fluorescein. Its disodium salt in ophthalmic solutions has been used as a diagnostic agent in suspected damage to conjunctival and corneal cells. It is also used in laboratory settings, including the preparation of Foraminifera for microscopic analysis and suppression...
Approved
Investigational
Matched Description: … and suppression of bacterial growth in several microbiological media. ... The clinical applications of rose bengal as injectable formulation under the name PV-10 in melanoma, ... It is also used in laboratory settings, including the preparation of Foraminifera for microscopic analysis …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Ertugliflozin

Ertugliflozin is a sodium-dependent glucose cotransporter-2 (SGLT2) inhibitor used to treat type II diabetes mellitus. It works to block glucose reabsorption from the glomerulus. Ertugliflozin was first approved by the FDA in December 2017.[A261951, L1132] It was also approved by the European Commission in March 2018.
Approved
Investigational
Matched Description: … [A31581] Ertugliflozin was first approved by the FDA in December 2017. ... [A261951, L1132] It was also approved by the European Commission in March 2018.[L48621] …
Matched Categories: … Drugs Used in Diabetes …

Theobroma cacao whole

Theobroma cacao, whole, allergenic extract is used in allergenic testing.
Approved
Matched Description: … Theobroma cacao, whole, allergenic extract is used in allergenic testing. …

Chloroprocaine

Chloroprocaine is an ester local anesthetic commonly available in its salt form, chloroprocaine hydrochloride. Similar to other local anesthetics, it increases the threshold for electrical excitation in nerves by slowing the propagation of the nerve impulse and reducing the rate of rise of the action potential. The pharmacological profile of...
Approved
Investigational
Matched Description: … slowing the propagation of the nerve impulse and reducing the rate of rise of the action potential. ... Similar to other local anesthetics, it increases the threshold for electrical excitation in nerves by ... Chloroprocaine is an ester local anesthetic commonly available in its salt form, chloroprocaine hydrochloride …
Matched Salts cas: … 3858-89-7 …
Matched Categories: … Esters of Aminobenzoic Acid …

Quinethazone

Quinethazone, marketed as Hydromox, is a thiazide diuretic indicated for hypertension. Patients may experience adverse reactions such as dizziness, dry mouth, nausea, and hypokalemia.
Approved
Matched Iupac: … 7-chloro-2-ethyl-4-oxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide …
Matched Categories: … combinations of sulfonamides …

Aminocaproic acid

An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
Approved
Investigational

Natamycin

Amphoteric macrolide antifungal antibiotic from Streptomyces natalensis or S. chattanoogensis. It is used for a variety of fungal infections, mainly topically. [PubChem]
Approved
Matched Description: … It is used for a variety of fungal infections, mainly topically. [PubChem] …

Masoprocol

A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in fats and oils. [PubChem]
Approved
Investigational
Matched Description: … It also serves as an antioxidant in fats and oils. [PubChem] …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Polidocanol

Polidocanol is a sclerosing agent indicated to treat uncomplicated spider veins (varicose veins ≤1 mm in diameter) and uncomplicated reticular veins (varicose veins 1 to 3 mm in diameter) in the lower extremity. It is marketed under the brand names Asclera and Varithena. The formula for Polidocanol has the structural...
Approved
Matched Description: … (n) of approximately 9 and a mean molecular weight of approximately 600. ... diameter) and uncomplicated reticular veins (varicose veins 1 to 3 mm in diameter) in the lower extremity ... Polidocanol is a sclerosing agent indicated to treat uncomplicated spider veins (varicose veins ≤1 mm in …
Matched Categories: … Compounds used in a research, industrial, or household setting …

p-Phenylenediamine

Approved
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …

Tetryzoline

Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral alpha (α)-adrenergic properties. Available since the 1950s, tetryzoline is a selective α1-receptor agonist that is used as an ocular and nasal decongestant. Tetryzoline is found in a wide array of over-the-counter eye drops, including the most...
Approved
Matched Description: … Tetryzoline is found in a wide array of over-the-counter eye drops, including the most common brand, ... of nasal and nasopharyngeal mucosa. ... Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral …
Matched Mixtures name: … Rohto All-In-One …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Sulfamethazine

A sulfanilamide anti-infective agent. It has a spectrum of antimicrobial action similar to other sulfonamides.
Approved
Investigational
Vet approved
Matched Description: … It has a spectrum of antimicrobial action similar to other sulfonamides. …
Matched Categories: … combinations of sulfonamides …

Quinupramine

Quinupramine has been approved in France under the brand name Kinupril, as an antidepressant .
Approved
Matched Description: … Quinupramine has been approved in France under the brand name Kinupril, as an antidepressant [A175003 …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Mianserin

A tetracyclic compound with antidepressant effects. Mianserin was previously available internationally, however in most markets it has been phased out in favour of mirtazapine.
Approved
Investigational
Matched Description: … favour of [mirtazapine]. ... Mianserin was previously available internationally, however in most markets it has been phased out in …
Matched Salts cas: … 21535-47-7 …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Citalopram

Citalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs.[A261316,A14720] Citalopram enhances serotonergic transmission through the...
Approved
Matched Description: … [A261316] Citalopram was approved by the FDA in 1998 for the treatment of depression in adults 18 ... SSRIs) widely used to treat the symptoms of depression. ... Citalopram is an antidepressant belonging to the class of selective _serotonin-reuptake inhibitors_ ( …
Matched Salts cas: … 59729-32-7 …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Displaying drugs 601 - 625 of 10948 in total