Displaying drugs 651 - 675 of 14163 in total
Desonide
A nonfluorinated corticosteroid anti-inflammatory agent used topically for dermatoses.
Approved
Investigational
Matched Iupac: … (1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[ …
Estradiol benzoate
Estradiol Benzoate is a pro-drug ester of DB00783, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex hormone. As a pro-drug of estradiol, estradiol benzoate therefore has the same downstream...
Approved
Investigational
Vet approved
Matched Description: … Following absorption, the esters are cleaved, resulting in the release of endogenous estradiol, or 17β-estradiol ... produced with an ester side-chain as endogenous estradiol has very low oral bioavailability on its own (2- ... Estradiol benzoate is not currently available in Canada or the US. …
Estrone sulfate
Estrone sulfate (as estropipate) is a form of estrogen. It has several uses such as: alleviate symptoms of menopause as hormone replacement therapy, treatment some types of infertility, treatment of some conditions leading to underdevelopment of female sexual characteristics, treatment of vaginal atrophy, treatment of some types of breast cancer...
Approved
Matched Description: … in men and postmenopausal women), treatment of prostate cancer and prevention of osteoporosis. ... some types of infertility, treatment of some conditions leading to underdevelopment of female sexual ... characteristics, treatment of vaginal atrophy, treatment of some types of breast cancer (particularly …
Matched Salts cas: … 1240-04-6 …
Matched Categories: … MATE 2 Substrates …
Matched Salts cas: … 1240-04-6 …
Matched Categories: … MATE 2 Substrates …
Ulobetasol
Ulobetasol is a highly potent corticosteroid. It is structurally related to clobetasol. Due to its high potency, it is mainly prescribed in the treatment of severe plaque psoriasis and corticosteroid responsive dermatoses.[L15047,L15052,L15102]
Ulobetasol was granted FDA approval on 17 December 1990.
Approved
Matched Iupac: … (1R,2S,8S,10S,11S,13S,14R,15S,17S)-14-(2-chloroacetyl)-1,8-difluoro-14,17-dihydroxy-2,13,15-trimethyltetracyclo …
Matched Description: … [A215597] Due to its high potency, it is mainly prescribed in the treatment of severe plaque psoriasis …
Matched Description: … [A215597] Due to its high potency, it is mainly prescribed in the treatment of severe plaque psoriasis …
Panthenol
Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Panthenol exists as a racemic mixture containing both the dextrorotatory form (dexpanthenol) and the levorotatory form (levopanthenol). While pantothenic acid is optically active, only the dextrorotatory...
Approved
Matched Description: … B5), which is an essential component of Coenzyme A that acts as a cofactor in many enzymatic reactions ... and accelerated re-epithelialization in wound healing. ... that are important for protein metabolism in the epithelium [A32373]. …
Matched Mixtures name: … Miracle Of Skin …
Matched Mixtures name: … Miracle Of Skin …
Famtozinameran
The Omicron variant of SARS-CoV-2 is a variant of concern that was first reported in November 2021. It tends to cause less severe disease but is significantly more virulent than both the original virus and earlier variants (e.g. Delta). As of November 2022, it is the primary circulating variant of...
Approved
Investigational
Matched Description: … The Omicron variant of SARS-CoV-2 is a variant of concern that was first reported in November 2021. ... [L43917]
Famtozinameran is an mRNA vaccine encoding the S glycoprotein of SARS-CoV-2 Omicron variant ... by SARS-CoV-2, including infection caused by Omicron BA.4/BA.5. …
Cortisone acetate
Cortisone acetate was first isolate in 1935 and became more widely researched in 1949. Since then, glucocorticoids such as cortisone acetate have been used to treat a number of inflammatory conditions such as endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, respiratory, hematologic, neoplastic, edematous, and gastrointestinal diseases and disorders.[A226300,L13203]
Cortisone acetate...
Approved
Investigational
Matched Iupac: … ,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate ... 2-[(1R,3aS,3bS,9aR,9bS,11aS)-1-hydroxy-9a,11a-dimethyl-7,10-dioxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH …
Matched Description: … Cortisone acetate was first isolate in 1935 and became more widely researched in 1949. ... [A226295] Since then, glucocorticoids such as cortisone acetate have been used to treat a number of inflammatory …
Matched Description: … Cortisone acetate was first isolate in 1935 and became more widely researched in 1949. ... [A226295] Since then, glucocorticoids such as cortisone acetate have been used to treat a number of inflammatory …
Aripiprazole lauroxil
Aripiprazole lauroxil is a long-acting injectable atypical antipsychotic drug used in the treatment of schizophrenia in adult patients. It is a prodrug of aripiprazole, which acts as a partial agonist at the D2 and 5-HT1A receptors, and as an antagonist at the 5-HT2A receptors .
Affecting about 1% of the...
Approved
Investigational
Matched Iupac: … (7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-2-oxo-1,2,3,4-tetrahydroquinolin-1-yl)methyl dodecanoate …
Matched Description: … schizophrenia resulted in improvement of positive and negative symptoms scores at day 85 of treatment ... In a randomized, double-blind clinical trial, treatment of aripiprazole lauroxil in adult patients with ... Aripiprazole lauroxil is a long-acting injectable atypical antipsychotic drug used in the treatment of …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Description: … schizophrenia resulted in improvement of positive and negative symptoms scores at day 85 of treatment ... In a randomized, double-blind clinical trial, treatment of aripiprazole lauroxil in adult patients with ... Aripiprazole lauroxil is a long-acting injectable atypical antipsychotic drug used in the treatment of …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Plazomicin
Developed by Achaogen biopharmaceuticals, plazomicin is a next-generation aminoglycoside synthetically derived from DB12604. The structure of plazomicin was established via appending hydroxylaminobutyric acid to DB12604 at position 1 and 2-hydroxyethyl group at position 6' . It was designed to evade all clinically relevant aminoglycoside-modifying enzymes, which contribute to the main...
Approved
Investigational
Matched Iupac: … (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-4-{[(2S,3R)-3-amino-6-{[(2-hydroxyethyl)amino]methyl}-3,4-dihydro ... -2H-pyran-2-yl]oxy}-2-{[(2R,3R,4R,5R)-3,5-dihydroxy-5-methyl-4-(methylamino)oxan-2-yl]oxy}-3-hydroxycyclohexyl ... ]-2-hydroxybutanamide …
Matched Description: … 1 and 2-hydroxyethyl group at position 6' [A33942]. ... On June 28th, 2018, plazomicin sulfate was approved by the FDA for use in adult patients for the treatment ... However, acquired resistance of aminoglycosides may arise through over expression of efflux pumps and …
Matched Categories: … MATE 2 Inhibitors …
Matched Description: … 1 and 2-hydroxyethyl group at position 6' [A33942]. ... On June 28th, 2018, plazomicin sulfate was approved by the FDA for use in adult patients for the treatment ... However, acquired resistance of aminoglycosides may arise through over expression of efflux pumps and …
Matched Categories: … MATE 2 Inhibitors …
Amlexanox
Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and rhinitis. Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers. Recurrent aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect between 5% and 50% of...
Approved
Investigational
Withdrawn
Matched Synonyms: … 2-Amino-7-isopropyl-5-oxo-5H-(1)benzopyrano(2,3-b)pyridine-3-carboxylic acid …
Matched Iupac: … 2-amino-5-oxo-7-(propan-2-yl)-5H-chromeno[2,3-b]pyridine-3-carboxylic acid …
Matched Description: … between 5% and 50% of the general population. ... Recurrent aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect ... Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers. …
Matched Iupac: … 2-amino-5-oxo-7-(propan-2-yl)-5H-chromeno[2,3-b]pyridine-3-carboxylic acid …
Matched Description: … between 5% and 50% of the general population. ... Recurrent aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect ... Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers. …
Pregabalin
Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter. It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other conditions. Although as per the FDA Label the mechanism of action has not been definitively characterized, there is evidence that pregabalin exerts its effects...
Approved
Investigational
Matched Description: … [L1006,L7066] It may have dependence liability if misused but the risk appears to be highest in patients ... [A187190] Although as per the FDA Label the mechanism of action has not been definitively characterized ... , there is evidence that pregabalin exerts its effects by binding to the α2δ subunit of voltage-dependent …
Chlorquinaldol
Chlorquinaldol was used historically as a topical antiseptic under the trade name Sterosan. It was marketed in the 1950s as an iodine-free alternative which was also unrelated to sulfa drugs or hormones. Chlorquinaldol is currently approved by the European Medicines Agency as a combination tablet with promestriene for the treatment...
Approved
Matched Synonyms: … 5,7-dichloro-2-methyl-8-quinolinol ... 2-methyl-5,7-dichloro-8-hydroxyquinoline ... 5,7-dichloro-2-methyl-8-hydroxyquinoline …
Matched Iupac: … 5,7-dichloro-2-methylquinolin-8-ol …
Matched Description: … [F4549] It was marketed in the 1950s as an iodine-free alternative which was also unrelated to sulfa ... approved by the European Medicines Agency as a combination tablet with promestriene for the treatment of …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 5,7-dichloro-2-methylquinolin-8-ol …
Matched Description: … [F4549] It was marketed in the 1950s as an iodine-free alternative which was also unrelated to sulfa ... approved by the European Medicines Agency as a combination tablet with promestriene for the treatment of …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Acetylcysteine
Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of acetaminophen overdose.[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.[A228158,A228163,A228168]
Acetylcysteine was granted FDA approval on 14 September 1963.
Approved
Investigational
Matched Synonyms: … (2R)-2-acetylamino-3-sulfanylpropanoic acid ... (R)-2-acetylamino-3-mercaptopropanoic acid …
Matched Iupac: … (2R)-2-acetamido-3-sulfanylpropanoic acid …
Matched Description: … Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of ... [L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications …
Matched Mixtures name: … AMINOPLASMAL 15% IN 500ML GLASS BOTTLE …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … FLUIMUCIL® 2% ... HYSTIN SOLUCIONORAL 2 % ... N-ACETILCISTEÍNA 2 G / 100 ML JARABE …
Matched Iupac: … (2R)-2-acetamido-3-sulfanylpropanoic acid …
Matched Description: … Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of ... [L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications …
Matched Mixtures name: … AMINOPLASMAL 15% IN 500ML GLASS BOTTLE …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … FLUIMUCIL® 2% ... HYSTIN SOLUCIONORAL 2 % ... N-ACETILCISTEÍNA 2 G / 100 ML JARABE …
Estradiol cypionate
Estradiol Cypionate is a pro-drug ester of DB00783, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex hormone. As a pro-drug of estradiol, estradiol cypionate therefore has the same downstream...
Approved
Investigational
Vet approved
Matched Description: … Because of the difference in potency between estradiol and estrone, menopause (and a change in primary ... produced with an ester side-chain as endogenous estradiol has very low oral bioavailability on its own (2- ... in potency and in estrogenic effects. …
Estradiol acetate
Estradiol acetate is a pro-drug ester of DB00783, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex hormone. As a pro-drug of estradiol, estradiol acetate therefore has the same downstream...
Approved
Investigational
Vet approved
Matched Description: … produced with an ester side-chain as endogenous estradiol has very low oral bioavailability on its own (2- ... Because of the difference in potency between estradiol and estrone, menopause (and a change in primary ... The primary source of estrogen in normally cycling adult women is the ovarian follicle, which secretes …
Estradiol valerate
Estradiol Valerate (also known as E2V) is a pro-drug ester of DB00783, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex hormone. As a pro-drug of estradiol, estradiol acetate therefore...
Approved
Investigational
Vet approved
Matched Description: … produced with an ester side-chain as endogenous estradiol has very low oral bioavailability on its own (2- ... Because of the difference in potency between estradiol and estrone, menopause (and a change in primary ... in potency and in estrogenic effects. …
Matched Mixtures name: … DIVINA 2 MG + 2 MG /10 MG TABLET, 21 ADET ... DIVINA 2 MG + 2 MG /10 MG TABLET, 21 ADET ... CYCLO-PROGYNOVA 2 MG+2 MG/0.5 MG KAPLI TABLET, 21 ADET …
Matched Products: … โปรกีโนวา 2 มก. ... PROGYNOVA ® 2 MG ... PROGYNOVA TABLET 2 mg …
Matched Mixtures name: … DIVINA 2 MG + 2 MG /10 MG TABLET, 21 ADET ... DIVINA 2 MG + 2 MG /10 MG TABLET, 21 ADET ... CYCLO-PROGYNOVA 2 MG+2 MG/0.5 MG KAPLI TABLET, 21 ADET …
Matched Products: … โปรกีโนวา 2 มก. ... PROGYNOVA ® 2 MG ... PROGYNOVA TABLET 2 mg …
Methsuximide
Mesuximide (or methsuximide) is an anticonvulsant medication. It is sold by Pfizer under the name Petinutin.
Approved
Matched Synonyms: … N,2-Dimethyl-2-phenylsuccinimide …
Gemeprost
Gemeprost is a prostaglandin E1 (PGE1) analog and antiprogestogen used for preoperative dilation of the cervix before surgical abortion. It is available as vaginal suppositories and also used in combination with the antiprogestin and mifepristone for termination of 1st- and 2nd-trimester pregnancy . It is not FDA-approved but available in...
Approved
Withdrawn
Matched Synonyms: … 16,16-Dimethyl-trans-delta-2-PGE1 methyl ester ... 16,16-Dimethyl-trans-delta(sup 2)-prostaglandin E1 methyl ester …
Matched Iupac: … hept-2-enoate ... methyl (2E)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3R)-3-hydroxy-4,4-dimethyloct-1-en-1-yl]-5-oxocyclopentyl] …
Matched Description: … for termination of 1st- and 2nd-trimester pregnancy [A19726]. ... It is not FDA-approved but available in Japan marketed as Preglandin. ... Gemeprost is a prostaglandin E1 (PGE1) analog and antiprogestogen used for preoperative dilation of the …
Matched Iupac: … hept-2-enoate ... methyl (2E)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3R)-3-hydroxy-4,4-dimethyloct-1-en-1-yl]-5-oxocyclopentyl] …
Matched Description: … for termination of 1st- and 2nd-trimester pregnancy [A19726]. ... It is not FDA-approved but available in Japan marketed as Preglandin. ... Gemeprost is a prostaglandin E1 (PGE1) analog and antiprogestogen used for preoperative dilation of the …
Methocarbamol
Methocarbamol was developed in the early 1950s as a treatment for muscle spasticity and the associated pain.[A178441,A178450] It is a guaiacol glyceryl ether. Methocarbamol tablets and intramuscular injections are prescription medicines indicated in the United States as an adjunct to rest, physical therapy, and other measures for the relief of...
Approved
Vet approved
Matched Synonyms: … (RS)-2-hydroxy-3-(2-methoxyphenoxy)propyl carbamate …
Matched Iupac: … 2-hydroxy-3-(2-methoxyphenoxy)propyl carbamate …
Matched Description: … the United States as an adjunct to rest, physical therapy, and other measures for the relief of discomforts ... Methocarbamol was developed in the early 1950s as a treatment for muscle spasticity and the associated ... A178450] Methocarbamol tablets and intramuscular injections are prescription medicines indicated in …
Matched Mixtures name: … Robaxisal C 1/2 ... Methoxisal-C 1/2 …
Matched Iupac: … 2-hydroxy-3-(2-methoxyphenoxy)propyl carbamate …
Matched Description: … the United States as an adjunct to rest, physical therapy, and other measures for the relief of discomforts ... Methocarbamol was developed in the early 1950s as a treatment for muscle spasticity and the associated ... A178450] Methocarbamol tablets and intramuscular injections are prescription medicines indicated in …
Matched Mixtures name: … Robaxisal C 1/2 ... Methoxisal-C 1/2 …
Doripenem
Doripenem is a broad-spectrum, carbapenem antibiotic marketed under the brand name Doribax by Janssen. Doripenem injection was approved by the FDA in 2007 to treat complicated urinary tract and intra-abdominal infections. In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin), it was found that...
Approved
Investigational
Matched Iupac: … yl]sulfanyl}-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid ... (4R,5S,6S)-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-3-{[(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3- …
Matched Description: … in a premature termination of the trial. ... In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin ... ), it was found that doripenem carried an increased risk of death and lower clinical cure rates, resulting …
Matched Salts cas: … 364622-82-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … in a premature termination of the trial. ... In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin ... ), it was found that doripenem carried an increased risk of death and lower clinical cure rates, resulting …
Matched Salts cas: … 364622-82-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Trypan blue free acid
Trypan blue is a diazo dye used in ophthalmic cataract surgery to stain the anterior capsule in the presence of a mature cataract. This is done to aid in visualization before creating the continuous curvilinear capsulorhexis.
Approved
Matched Iupac: … 5-amino-3-[(E)-2-{4'-[(E)-2-(8-amino-1-hydroxy-3,6-disulfonaphthalen-2-yl)diazen-1-yl]-3,3'-dimethyl- …
Matched Description: … of a mature cataract. ... Trypan blue is a diazo dye used in ophthalmic cataract surgery to stain the anterior capsule in the presence ... This is done to aid in visualization before creating the continuous curvilinear capsulorhexis. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Description: … of a mature cataract. ... Trypan blue is a diazo dye used in ophthalmic cataract surgery to stain the anterior capsule in the presence ... This is done to aid in visualization before creating the continuous curvilinear capsulorhexis. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Carglumic acid
Carglumic acid is a drug used for the treatment of hyperammonemia in patients with a deficiency in N-acetyl glutamate synthase. This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the blood–brain barrier and cause neurologic problems, cerebral edema, coma, and death. Carglumic acid was...
Approved
Matched Synonyms: … (S)-2-ureidopentanedioic acid ... (2S)-2-(carbamoylamino)pentanedioic acid …
Matched Iupac: … (2S)-2-(carbamoylamino)pentanedioic acid …
Matched Description: … Carglumic acid is a drug used for the treatment of hyperammonemia in patients with a deficiency in N-acetyl ... This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the …
Matched Iupac: … (2S)-2-(carbamoylamino)pentanedioic acid …
Matched Description: … Carglumic acid is a drug used for the treatment of hyperammonemia in patients with a deficiency in N-acetyl ... This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the …
Alogliptin
Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 (DPP-4). Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer. FDA approved January 25, 2013.
Approved
Matched Iupac: … 2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl}methyl)benzonitrile …
Matched Description: … It undergoes little or no chiral conversion in vivo to the (S)-enantiomer. ... Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase …
Matched Salts cas: … 850649-62-6 …
Matched Categories: … Drugs Used in Diabetes …
Matched Description: … It undergoes little or no chiral conversion in vivo to the (S)-enantiomer. ... Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase …
Matched Salts cas: … 850649-62-6 …
Matched Categories: … Drugs Used in Diabetes …
Elotuzumab
Elotuzumab is a humanized IgG1 (Immunoglobulin G) monoclonal antibody indicated in combination with lenalidomide and dexamethasone for the treatment of patients with multiple myeloma who have received one to three prior therapies. Elotuzumab targets SLAMF7, also known as Signaling Lymphocytic Activation Molecule Family member 7, a cell surface glycoprotein. Elotuzumab...
Approved
Matched Description: … Elotuzumab is produced in NS0 cells by recombinant DNA technology. ... Elotuzumab consists of the complementary determining regions (CDR) of the mouse antibody, MuLuc63, grafted ... Elotuzumab is a humanized IgG1 (Immunoglobulin G) monoclonal antibody indicated in combination with lenalidomide …
Melphalan flufenamide
Melphalan flufenamide, also known as melflufen or J1, is a prodrug of melphalan.[A230123,L32173] Melphalan flufenamide is more readily uptaken by cells than melphalan, and is cleaved to the active metabolite by aminopeptidases. In vitro models show that melphalan is 10 to hundreds of times more potent than melphalan. The increased...
Approved
Withdrawn
Matched Iupac: … ethyl (2S)-2-[(2S)-2-amino-3-{4-[bis(2-chloroethyl)amino]phenyl}propanamido]-3-(4-fluorophenyl)propanoate …
Matched Description: … It has since been withdrawn from the market in the wake of the phase 3 OCEAN trial which showed a decrease ... in overall survival in comparison to standard treatment with [pomalidomide] and [dexamethasone] despite ... Melphalan flufenamide, also known as melflufen or J1, is a prodrug of [melphalan]. …
Matched Description: … It has since been withdrawn from the market in the wake of the phase 3 OCEAN trial which showed a decrease ... in overall survival in comparison to standard treatment with [pomalidomide] and [dexamethasone] despite ... Melphalan flufenamide, also known as melflufen or J1, is a prodrug of [melphalan]. …
Displaying drugs 651 - 675 of 14163 in total