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Displaying drugs 651 - 675 of 5385 in total
Golimumab is a human IgG1қ monoclonal antibody derived from immunizing genetically engineered mice with human TNFα. Golimumab binds and inhibits soluble and transmembrane human TNFα. Increased TNFα is associated with chronic inflammation. Thus golimumab is indicated for use in adults (i) as an adjunct to methotrexate treatment in patients with...
Approved
Matched Description: … Golimumab binds and inhibits soluble and transmembrane human TNFα. ... Additionally in children and adolescents taking golimumab, there have been lymphoma and other malignancies ... In the U.S. and Canada, golimumab is marketed under the brand name Simponi®. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … SIMPONI 50 MG ENJEKSİYONLUK COZELTİ ICEREN KULLANIMA HAZIR ENJEKTOR, 3 ADET ... SIMPONI 50 MG PEN ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 3 ADET ... Solution for Injection in Pre-filled Syringe 100 mg/1.0 ml …
A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension.
Approved
Matched Synonyms: … (5Z,9α,11α,13E,15S)-6,9-epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid ... (5Z,13E)-(15S)-6,9alpha-Epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate …
Matched Iupac: … 5-[(2Z,3aR,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-hexahydro-2H-cyclopenta[b]furan-2- …
Matched Description: … A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. ... The sodium salt has been also used to treat primary pulmonary hypertension. …
Matched Salts cas: … 61849-14-7 …
Matched Salts name: … Epoprostenol sodium
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … Epoprostenol Sodium ... VELETRI® 1.5 MG ... SOLSİTAR 1,5 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 FLAKON + 1 ÇÖZÜCÜ İÇEREN FLAKON …
Dupilumab is a fully human monoclonal antibody of the immunoglobulin G4 subclass that binds to the interleukin-4 (IL-4) receptor, inhibiting the receptor signaling pathways. As an interleukin-4 receptor alpha antagonist, dupilumab inhibits the signaling of pro-inflammatory cytokines, called interleukins (IL), that induce inflammatory and immunological reactions in several atopic or...
Approved
Investigational
Matched Description: … It is also being studied in combination with another antibody that which targets IL-33.[L7225] ... immunological reactions in several atopic or allergic conditions, such as eczema, allergic reaction, and ... inhibits the signaling of pro-inflammatory cytokines, called interleukins (IL), that induce inflammatory and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents …
Matched Products: … DUPİXENT 150 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 3 ADET ... Dupixent 175 mg/ml Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Enjektör, 3 ADET ... DUPİXENT 150 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 3 ADET, İĞNE KORUMASI OLAN …
Experimental
Matched Synonyms: … Indoxyl sulfic acid ... 3-indolyl sulfate ... 3-Indoxyl sulfate …
Matched Iupac: … (1H-indol-3-yl)oxidanesulfonic acid …
A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. (Merck, 11th ed) The FDA withdrew its...
Approved
Investigational
Withdrawn
Matched Synonyms: … (E)-4,4'-(1,2-diethyl-1,2-ethenediyl)bisphenol ... trans-4,4'-(1,2-diethyl-1,2-ethenediyl)bisphenol ... (E)-3,4-bis(4-hydroxyphenyl)-3-hexene …
Matched Iupac: … 4-[(3E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol …
Matched Description: … A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. ... (Merck, 11th ed) The FDA withdrew its approval for the use of all oral and parenteral drug products …
Matched Salts name: … Diethylstilbestrol diphosphate sodium
Matched Categories: … Hormones and Related Agents ... Antineoplastic and Immunomodulating Agents ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Stilbestrol Tab 1mg ... Stilbestrol Tablets 1.0 mg …
Nisoldipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nisoldipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. Nisoldipine may be used in alone...
Approved
Matched Synonyms: … isobutyl methyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Iupac: … 3-methyl 5-(2-methylpropyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … of calcium in smooth muscle cells, nisoldipine prevents calcium-dependent smooth muscle contraction and ... Nisoldipine is a 1,4-dihydropyridine calcium channel blocker. …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Heterocyclic Compounds, 1-Ring …
Matched Products: … Sular
One of the benzodiazepines that is used in the treatment of anxiety disorders. It is a Schedule IV drug in the U.S. and Canada and under the Convention on Psychotropic Substances. It is a intermediate-acting benzodiazepine.
Approved
Illicit
Investigational
Matched Iupac: … 7-bromo-5-(pyridin-2-yl)-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Description: … It is a Schedule IV drug in the U.S. and Canada and under the Convention on Psychotropic Substances. …
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives …
Matched Products: … BROMAZEPAM FARMA 1 ... LEXOTAN TABLET 1.5 mg ... BROMAZEPAM 6 1A PHARMA …
Investigational
Matched Synonyms: … d-tryptophyl-, sodium salt (1:1) ... D-norleucine, n-(((2r,6s)-2,6-dimethyl-1-piperidinyl)carbonyl)-4-methyl-l-leucyl-1-(methoxycarbonyl)- …
Matched Iupac: … ]-3-[1-(methoxycarbonyl)-1H-indol-3-yl]propanamido]hexanoate ... sodium (2R)-2-[(2R)-2-[(2S)-2-{[(2R,6S)-2,6-dimethylpiperidine-1-carbonyl]amino}-4,4-dimethylpentanamido …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Heterocyclic Compounds, 1-Ring …
Experimental
Matched Synonyms: … 1,3-propylene glycol ... Propane-1,3-diol ... 1,3-Dihydroxypropane …
Matched Name: … 1,3-Propanediol …
Matched Iupac: … propane-1,3-diol …
Gandotinib has been used in trials studying the treatment of Myelofibrosis, Polycythemia Vera, Primary Myelofibrosis, Thrombocythemia, Essential, and Myeloproliferative Disorders, among others.
Investigational
Matched Synonyms: … 3-(4-CHLORO-2-FLUOROBENZYL)-2-METHYL-N-(5-METHYL-1H-PYRAZOL-3-YL)-8- (MORPHOLINOMETHYL)IMIDAZO(1,2-B) ... IMIDAZO(1,2-B)PYRIDAZIN-6-AMINE, 3-((4-CHLORO-2-FLUOROPHENYL)METHYL)-2-METHYL-N-(5- METHYL-1H-PYRAZOL ... -3-YL)-8-(4-MORPHOLINYLMETHYL)- …
Matched Iupac: … N-{3-[(4-chloro-2-fluorophenyl)methyl]-2-methyl-8-[(morpholin-4-yl)methyl]imidazo[1,2-b]pyridazin-6-yl ... }-5-methyl-1H-pyrazol-3-amine …
Matched Description: … the treatment of Myelofibrosis, Polycythemia Vera, Primary Myelofibrosis, Thrombocythemia, Essential, and
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Castor oil is a vegetable oil obtained by pressing the seeds of the castor oil plant (Ricinus communis L.) mainly cultivated in India, South America, Africa, and China. Castor oil is a rich source of DB02955, which represents up to 90% of the total castor oil content. It also consists...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … It also consists up to 4% linoleic, 3% oleic, 1% stearic, and less than 1% linolenic fatty acids [A31170 ... cosmetic, hair, and skincare products. ... and mineral oral tablets as an ingredient for protective coatings. …
Matched Mixtures name: … Zinc and Castor Oil Crm ... Zinc and Castor Oil Cream BP …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Foster and Thrive Castor Oil ... Castor Oil Liq 100% ... RICIMENT 120 ML EMULSIYON …
Ketotifen is a benzocycloheptathiophene derivative with potent antihistaminic and mast cell stabilizing properties. It has a similar structure to some other first-generation antihistamines such as cyproheptadine and azatadine. Ketotifen was first developed in Switzerland in 1970 by Sandoz Pharmaceuticals and was initially marketed for the treatment of anaphylaxis. In the...
Approved
Matched Iupac: … 2-(1-methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.0^{3,7}]tetradeca-1(14),3(7),4,10,12-pentaen-8-one …
Matched Description: … allergic symptoms and disorders,[A231204] including urticaria, mastocytosis, and food allergy. ... Ketotifen is a benzocycloheptathiophene derivative[A231204] with potent antihistaminic and mast cell ... It has a similar structure to some other first-generation antihistamines such as [cyproheptadine] and
Matched Salts cas: … 34580-14-8 …
Matched Categories: … Decongestants and Antiallergics ... Sulfur Compounds ... Heterocyclic Compounds, 1-Ring …
Matched Products: … Up and Up Eye Itch Relief ... MİTOFEN 1 MG TABLET, 30 ADET ... ZADITEN 1 MG TABLET, 30 ADET …
Experimental
Matched Synonyms: … 4-Isopropyl-1,5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one ... 1-Phenyl-2,3-dimethyl-4-isopropyl-3-pyrazolin-5-one ... 1-Phenyl-2,3-dimethyl-4-isopropylpyrazol-5-one …
Matched Iupac: … 1,5-dimethyl-2-phenyl-4-(propan-2-yl)-2,3-dihydro-1H-pyrazol-3-one …
Matched Mixtures name: … DERMAN 300/100/50 MG KAŞE, 1 KAŞE ... ALJIL 150 MG/300 MG/50 MG TABLET, 20 ADET ... MINOSET PLUS 250 MG/150 MG/50 MG TABLET, 30 ADET …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Garcinia gummi-gutta fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Garcinia Cambogia (Constituent of Garcinia Cambogia and Garcinia Indica) …
Tefidsogene civaparvovec, formerly known as SB-913, is an investigational therapy for genome editing. It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system that inserts a correct copy of the Iduronate 2-Sulfatase (IDS) gene into the albumin locus in hepatocytes. Developed by Sangamo...
Experimental
Matched Synonyms: … PLUS EXONS 2-9 FROM HIDS AND A SPLICE ACCEPTOR SITE (SA) ... CONTAINS A PROMOTER-LESS HUMAN IDURONATE 2-SULFATASE (HIDS) TRANSGENE CASSETTE, ENCODING PARTS OF EXON 1
Matched Description: … It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system …
Investigational
Matched Synonyms: … 2-amino-n-(3-(benzyloxy)-1-(1-methanesulfonyl-1,2-dihydrospiro(indole-3,4'-piperidin)-1'-yl)-1-oxopropan ... 2-amino-n-((r)-2-(benzyloxy)-1-((1-(methylsulfonyl)spiro(indoline-3,4'-piperidin)-1'-yl)carbonyl)ethyl …
Matched Iupac: … 2-amino-N-[(2R)-3-(benzyloxy)-1-{1-methanesulfonyl-1,2-dihydrospiro[indole-3,4'-piperidin]-1'-yl}-1-oxopropan …
Matched Salts cas: … 159752-10-0 …
Experimental
Matched Name: … Potassium hydrogen DL-aspartate …
Matched Iupac: … potassium 3-amino-3-carboxypropanoate …
Matched Mixtures name: … Trommcardin K 120 - Infusionsflasche …
Used as an agent for cleaning drinking water. It is also used as an additive in products like toothpaste and mouthwash. Acidified sodium chlorite was approved by the U.S. Food and Drug Administration as of 2004, as an anti-microbial agent which is non-toxic, but not as a drug [A174811, L5413].
Experimental
Matched Name: … Sodium chlorite …
Matched Iupac: … sodium chlorite …
Matched Description: … Acidified sodium chlorite was approved by the U.S. ... It is also used as an additive in products like toothpaste and mouthwash. ... Food and Drug Administration as of 2004, as an anti-microbial agent which is non-toxic, but not as a …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers ... sodium chlorite …
Experimental
Matched Name: … Sodium nitrate …
Matched Iupac: … sodium nitrate …
Ginseng is promoted as an adaptogen (a product that increases the body's resistance to stress), one which can to a certain extent be supported with reference to its anticarcinogenic and antioxidant properties. Ginseng is also known to contain phytoestrogens.
Investigational
Nutraceutical
Matched Description: … resistance to stress), one which can to a certain extent be supported with reference to its anticarcinogenic and
Matched Mixtures name: … Shine Oramin Natural Korean Ginseng + Royal Jelly with Multivitamins and Minerals. …
Matched Categories: … Herbs and Natural Products …
Matched Products: … Power / Vacsu Power (Dynamic and Powerful 99 year life) ... SINGISO 101 (0.8g) ... SINGISO 102 (0.8g) …
3-methyl-benzene-1,2-diol is a solid. This compound belongs to the catechols. These are compounds containing a 1,2-benzenediol moeity. 3-methyl-benzene-1,2-diol targets the protein biphenyl-2,3-diol 1,2-dioxygenase.
Experimental
Matched Name: … 3-methyl-benzene-1,2-diol …
Matched Iupac: … 3-methylbenzene-1,2-diol …
Matched Description: … These are compounds containing a 1,2-benzenediol moeity. 3-methyl-benzene-1,2-diol targets the protein ... 3-methyl-benzene-1,2-diol is a solid. This compound belongs to the catechols. ... biphenyl-2,3-diol 1,2-dioxygenase. …
Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.
Approved
Vet approved
Matched Description: … Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and
Matched Salts cas: … 136-47-0 …
Matched Mixtures name: … Lidocaine and Tetracaine ... Lidocaine and Tetracaine ... Benzocaine 20% / Lidocaine 10% / Tetracaine 10% …
Matched Categories: … Antipruritics and Local Anesthetics ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … MINIMS TETRACAINE HYDROCHLORIDE EYE DROPS 1% w/v ... Blt 3 ... FranklyNumb 3
Nepafenac is a non-steroidal anti-inflammatory prodrug (NSAID) usually sold as a prescription eye drop. It is used to treat pain and inflammation associated with cataract surgery.
Approved
Investigational
Matched Synonyms: … 2-amino-3-benzoylbenzeneacetamide …
Matched Iupac: … 2-(2-amino-3-benzoylphenyl)acetamide …
Matched Description: … It is used to treat pain and inflammation associated with cataract surgery. …
Matched Products: … NEVANAC 3 MG/ML GÖZ DAMLASI, SÜSPANSİYON ... Eye Drops Suspension 1 mg/ml ... MYRZA % 0.1 GÖZ DAMLASI, SÜSPANSİYON , 1 ADET …
Vudalimab is under investigation in clinical trial NCT05005728 (Xmab®20717 (Vudalimab) Alone or in Combination With Chemotherapy or Targeted Therapy in Patients With Metastatic Castration-resistant Prostate Cancer).
Investigational
Matched Synonyms: … kappa/scfv-h-ch2-ch3, anti-(homo sapiens ctla4 (cytotoxic t-lymphocyte-associated protein 4, cd152)) and ... anti-(homo sapienspdcd1 (programmed cell death 1, pd-1, pd1, cd279)), monoclonal antibody, bispecific ... Pd-1 x ctla-4 dual checkpoint inhibitor xmab20717 …
Teicoplanin is a glycopeptide antibiotic consisting of a mixture of several compounds, five major (named teicoplanin A2-1 through A2-5) and four minor (named teicoplanin RS-1 through RS-4). All teicoplanins share a same glycopeptide core, teicoplanin A3-1, but differ in the length and conformation of side chains attached to their β-D-glucosamine...
Approved
Investigational
Matched Iupac: … (1S,2R,19R,22R,34S,37R,40R,52S)-22-amino-5,63-dichloro-64-{[(2S,3R,4R,5S,6R)-3-decanamido-4,5-dihydroxy ... }.2^{19,34}.1^{8,12}.1^{23,27}.1^{29,33}.1^{41,45}.0^{10,37}.0^{46,51}]hexahexaconta-3,5,8(64),9,11,14,16,23,25,27 ... -6-(hydroxymethyl)oxan-2-yl]oxy}-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan ... -2-yl]oxy}-26,31,44,49-tetrahydroxy-21,35,38,54,56,59-hexaoxo-47-{[(3S,4S,5S,6R)-3,4,5-trihydroxy-6-( ... hydroxymethyl)oxan-2-yl]oxy}-7,13,28-trioxa-20,36,39,53,55,58-hexaazaundecacyclo[38.14.2.2^{3,6}.2^{14,17 …
Matched Description: … through A2-5) and four minor (named teicoplanin RS-1 through RS-4). ... All teicoplanins share a same glycopeptide core, teicoplanin A3-1, but differ in the length and conformation ... glycopeptide antibiotic consisting of a mixture of several compounds, five major (named teicoplanin A2-1
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … TARGOCID 200 MG/3 ML IM/IV ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET ... TARGOCID 400 MG/3 ML IM/IV ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET ... TEİPLACİD 200 MG IV/IM ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 3 ML …
Displaying drugs 651 - 675 of 5385 in total