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Displaying drugs 51 - 75 of 12132 in total
A semi-synthetic antibiotic related to penicillin, Naficillin is a narrow-spectrum beta-lactam antibiotic drug. It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections caused by strains that are resistant to other penicillins, except those caused by MRSA. It may be used as a first-line therapy in...
Approved
Investigational
Matched Synonyms: … (2-ethoxy-1-naphthyl)penicillin ... (2-ethoxy-1-naphthalenyl)penicillin ... (2S,5R,6R)-6-[(2-ethoxy-1-naphthoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic …
Matched Iupac: … (2S,5R,6R)-6-(2-ethoxynaphthalene-1-amido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Ethchlorvynol is a sedative and hypnotic drug. It has been used to treat insomnia, but has been largely superseded and is only offered where an intolerance or allergy to other drugs exists.
Approved
Illicit
Withdrawn
Matched Synonyms: … 1-chloro-3-ethyl-1-penten-4-yn-3-ol ... 1-Chloro-3-ethyl-pent-1-en-4-yn-3-ol ... 3-(β-chlorovinyl)-1-pentyn-3-ol …
Matched Iupac: … (1E)-1-chloro-3-ethylpent-1-en-4-yn-3-ol …
Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. It was first authorized for use in the US in November 2001 and in Europe in April 2002. Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to...
Approved
Investigational
Matched Synonyms: … (1R,5S,6S,8R,2'S,4'S)-2-(2-(3-carboxyphenylcarbamoyl)pyrrolidin-4-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapenem ... -7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid ... (4R,5S,6S)-3-((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl …
Matched Iupac: … ]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid ... (4R,5S,6S)-3-{[(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl …
Matched Description: … Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. …
Matched Salts cas: … 153773-82-1
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … ERTAGRAM® 1 G ... INVANZ 1 G IM/IV ENEJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADET ... INVANZ FOR INJECTION 1 g/vial …
A cardioselective beta-1-adrenergic antagonist with no partial agonist activity.
Approved
Investigational
Matched Synonyms: … 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-2-propanol ... 1-(isopropylamino)-3-[p-(cyclopropylmethoxyethyl)phenoxy]-2-propanol …
Matched Iupac: … 1-{4-[2-(cyclopropylmethoxy)ethyl]phenoxy}-3-[(propan-2-yl)amino]propan-2-ol …
Matched Description: … A cardioselective beta-1-adrenergic antagonist with no partial agonist activity. …
Matched Categories: … Adrenergic beta-1 Receptor Antagonists …
Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral alpha (α)-adrenergic properties. Available since the 1950s, tetryzoline is a selective α1-receptor agonist that is used as an ocular and nasal decongestant. Tetryzoline is found in a wide array of over-the-counter eye drops, including the most...
Approved
Matched Synonyms: … 2-(1,2,3,4-Tetrahydro-1-naphthyl)-2-imidazoline ... 2-Tetralin-1-yl-4,5-dihydro-1H-imidazole ... (RS)-2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole …
Matched Iupac: … 2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole …
Matched Description: … [A231769] Available since the 1950s, tetryzoline is a selective α1-receptor agonist [A231774 …
Matched Categories: … Adrenergic alpha-1 Receptor Agonists ... Heterocyclic Compounds, 1-Ring …
Matched Products: … Murine Plus 2
Approved
Matched Synonyms: … Iron(2+) gluconate (1:2) ... D-gluconic acid, iron(2+) salt (2:1) …
Matched Iupac: … lambda2-iron(2+) bis((2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate) …
Matched Mixtures name: … Swical-energy-2 ... Vege 1 Daily Tab ... BioFerr 90
Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness,...
Approved
Investigational
Vet approved
Matched Synonyms: … 2,6-bis(1-methylethyl)phenol …
Matched Iupac: … 2,6-bis(propan-2-yl)phenol …
Matched Products: … DORMOFOL % 2 1000 MG/50 ML IV İNFÜZYONLUK/ENJEKSİYONLUK EMÜLSİYON, 1 ADET ... Fresenius Propoven 2% ... DIPRIVAN 2 % …
Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or in anesthesia.[Label,L6598,L6601,L6604,L6607,L922,L6610,L6613] Fentanyl is related to other opioids like morphine and oxycodone. Fentanyl's high potency has also...
Approved
Illicit
Investigational
Vet approved
Matched Synonyms: … N-phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)propanamide ... 1-phenethyl-4-N-propionylanilinopiperidine ... 1-Phenethyl-4-(N-phenylpropionamido)piperidine …
Matched Iupac: … N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide …
Matched Description: … [A179542] In 2017, 47600 overdose deaths in the United States involved some opioid (over 2/3 of all overdose …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... FENTAVER 0,5 MG/10 ML IV/IM ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... TALINAT 0.5 MG/10 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL, 1 ADET …
Pindolol is a first generation non-selective beta blocker used in the treatment of hypertension. Early research into the use of pindolol found it had chronotropic effects, and so further investigation focused on the treatment of arrhythmia. Research into pindolol's use in the treatment of hypertension began in the early 1970s....
Approved
Investigational
Matched Synonyms: … 1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)-propan-2-ol ... 1-(1H-indol-4-yloxy)-3-[(1-methylethyl)amino]propan-2-ol ... 1-(1H-indol-4-yloxy)-3-(isopropylamino)propan-2-ol …
Matched Iupac: … 1-(1H-indol-4-yloxy)-3-[(propan-2-yl)amino]propan-2-ol …
Parathyroid hormone (PTH) is a single-chain polypeptide composed of 84 amino acids. Available as Preotact, it is an identical form of human recombinant hormome which produced as a fusion protein undergoeing post-translational processing involving the cleavage of the OmpA leader sequence, leaving the mature protein as a single-chain 84 amino-acids...
Approved
Investigational
Matched Synonyms: … PTH(1-84) ... rPTH(1-84) ... rhPTH(1-84) …
Ciclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. In particular, the agent is especially effective in treating Tinea versicolor.
Approved
Investigational
Matched Synonyms: … 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone …
Matched Iupac: … 6-cyclohexyl-1-hydroxy-4-methyl-1,2-dihydropyridin-2-one …
Matched Salts cas: … 41621-49-2
Matched Mixtures name: … Ciclopirox Olamine 1% / Salicylic Acid 2% ... Ciclopirox 0.77% / Salicylic Acid 2% ... Ciclopirox 8% / Fluconazole 1% / Terbinafine HCl 1% …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Loprox Crm 1% ... Loprox Cream 1% ... Loprox Lotion 1% …
A sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide.
Approved
Investigational
Matched Synonyms: … 1-(Hexahydro-1-azepinyl)-3-p-tolylsulfonylurea ... 1-(Hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)urea …
Matched Iupac: … 1-(azepan-1-yl)-3-(4-methylbenzenesulfonyl)urea …
Imiquimod is an immune response modifier that acts as a toll-like receptor 7 agonist. Imiquimod is commonly used topically to treat warts on the skin of the genital and anal areas. Imiquimod does not cure warts, and new warts may appear during treatment. Imiquimod does not fight the viruses that...
Approved
Investigational
Matched Synonyms: … 1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine ... 4-Amino-1-isobutyl-1H-imidazo(4,5-c)quinoline …
Matched Iupac: … 1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine …
Matched Mixtures name: … Imiquimod 5% / Levocetirizine Dihydrochloride 1% / Niacinamide 2% ... Imiquimod 5% / Levocetirizine Dihydrochloride 1% / Tretinoin 0.05% …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … QUIMARA-1
Formoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001. It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic mixture of its active (R;R)- and inactive (S;S)-enantiomers....
Approved
Investigational
Matched Synonyms: … N-[2-hydroxy-5-(1-hydroxy-2-{[2-(4-methoxyphenyl)-1-methylethyl]amino}ethyl)phenyl]formamide ... 2'-hydroxy-5'-(1-hydroxy-2-((p-methoxy-α-methylphenethyl)amino)ethyl)formanilide ... 2'-hydroxy-5'-{1-hydroxy-2-[(p-methoxy-α-methylphenethyl)amino]ethyl}formanilide …
Matched Iupac: … N-[2-hydroxy-5-(1-hydroxy-2-{[1-(4-methoxyphenyl)propan-2-yl]amino}ethyl)phenyl]formamide …
Matched Description: … Formoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was ... major clinical advantage of formoterol over other inhaled beta-agonists is its rapid onset of action (2- …
Matched Categories: … Adrenergic beta-2 Receptor Agonists ... Selective Beta 2-adrenergic Agonists …
Matched Products: … FORADIL P + 1 INHALATOR ... FOSTHMA 20 MCG / 2 ML NEBÜLİZASYON İÇİN TEK DOZLUK İNHALASYON ÇÖZELTİSİ, 30 ADET ... FOSTHMA 20 MCG / 2 ML NEBÜLİZASYON İÇİN TEK DOZLUK İNHALASYON ÇÖZELTİSİ, 60 ADET …
Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.
Approved
Matched Synonyms: … 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine …
Matched Iupac: … 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Mitapivat is a novel, first-in-class pyruvate kinase activator. It works to increase the activity of erythrocyte pyruvate kinase, a key enzyme involved in the survival of red blood cells. Defects in the pyruvate kinase enzyme in various red blood cells disorders lead to the lack of energy production for red...
Approved
Investigational
Matched Synonyms: … Pkr-in-1
Matched Iupac: … N-{4-[4-(cyclopropylmethyl)piperazine-1-carbonyl]phenyl}quinoline-8-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Povidone, also known as polyvinylpyrrolidone (PVP) or polyvidone, is a synthetic water-soluble polymer made from the monomer N-vinylpyrrolidone used as a binder in many pharmaceutical tablets and lubricant in eye drops. It is also used in many technical applications with various roles as an adhesive, additive, and emulsifier. When in...
Approved
Withdrawn
Matched Synonyms: … 1-vinyl-2-pyrrolidinone polymer ... 1-ethenyl-2-pyrrolidinone homopolymer …
Matched Mixtures name: … Murine Tears 1
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … VIDISEPT 2% …
A semi-synthetic cephalosporin antibiotic.
Approved
Matched Synonyms: … (6R,7R)-7-((R)-2-Amino-2-(1,4-cyclohexadien-1-yl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0) ... (6R,7R)-7-{[(2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0 ... oct-2-ene-2-carboxylic acid …
Matched Iupac: … (6R,7R)-7-[(2R)-2-amino-2-(cyclohexa-1,4-dien-1-yl)acetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0 ... ]oct-2-ene-2-carboxylic acid …
Matched Salts cas: … 75975-70-1
Matched Categories: … MATE 1 Substrates ... Heterocyclic Compounds, 2-Ring …
Matched Products: … CEFRADINA 1 G ... CEFRADINA 1 G. ... CEFADRIL TABLETAS 1 G. …
Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up 25% of the mixture. Labetalol is formulated as an injection or tablets to treat hypertension.[L7727,L7730] Labetalol was granted FDA approval on 1 August 1984.
Approved
Matched Synonyms: … 5-(1-Hydroxy-2-(1-methyl-3-phenylpropylamino)ethyl)salicylamide ... 3-Carboxamido-4-hydroxy-alpha-((1-methyl-3-phenylpropylamino)methyl)benzyl alcohol …
Matched Iupac: … 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide …
Matched Description: … [L7727,L7730] Labetalol was granted FDA approval on 1 August 1984.[L7724] ... Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up …
Matched Categories: … Peripheral alpha-1 blockers ... Adrenergic alpha-1 Receptor Antagonists …
Iothalamic acid is an iodine containing organic anion used as a diagnostic contrast agent.
Approved
Matched Synonyms: … 1-deoxy-1-(methylamino)-D-glucitol 5-acetamido-2,4,6 triiodo-N-methylisophthalamate …
Matched Salts cas: … 13087-53-1
Approved
Matched Synonyms: … 1-deoxy-1-methylaminosorbitol …
Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein involved in the innate immune system to initiate inflammatory responses. On October 17, 2023, zilucoplan gained its first FDA approval for the treatment of...
Approved
Matched Synonyms: … POLY(OXY-1,2-ETHANEDIYL), .ALPHA.-(2-(((4S)-4-CARBOXY-1-OXO-4-(1-OXOHEXADECYL)BUTYL)AMINO)ETHYL)-.OMEGA ... -GLUTAMYL-L-TYROSYL-L-PROLYL-(2S)-2-CYCLOHEXYLGLYCYL-N6-(3 …
Matched Iupac: … (2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{1-[(2S,5S,8S,11S,14S,22S)-11 ... yl]formamido}-2-cyclohexylacetamido]-6-{1-[(4S)-4-carboxy-4-hexadecanamidobutanamido]-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72 ... -benzyl-8-(3-carbamimidamidopropyl)-5-(2-carboxyethyl)-22-acetamido-3,6,9,12,16,23-hexaoxo-2-(propan- ... 1H-pyrrolo[2,3-b]pyridin-3-yl}propanamido]-4-carboxybutanamido]-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2- ... 2-yl)-1,4,7,10,13,17-hexaazacyclotricosan-14-yl]-N-methylformamido}-3-carboxypropanamido]-3,3-dimethylbutanamido …
Clobazam belongs to the 1,5-benzodiazepine class of drugs and is marketed under different names, Onfi, Frisium, Urbanyl, and others. . Clobazam was first synthesized in 1966 and first published in 1969, following the incidental synthesis and discovery of the first benzodiazepine chlordiazepoxide in the 1950s. Unlike older 1,4-benzodiazepines, clobazam has...
Approved
Illicit
Matched Synonyms: … 7-Chloro-1-methyl-5-phenyl-1,5-dihydro-benzo[b][1,4]diazepine-2,4-dione ... 1-phenyl-5-methyl-8-chloro-1,2,4,5-tetrahydro-2,4-dioxo-3H-1,5-benzodiazepine …
Matched Iupac: … 7-chloro-1-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine-2,4-dione …
Matched Description: … [A256963,A256868] This is likely because of clobazam's higher affinity to the α2 subunit of ... the GABAA receptor, which mediates anxiolytic effects, than the α1 subunit, which …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Clobazam Essential Pharmaceuticals 1 mg/ml Suspension zum Einnehmen …
All drug products containing encainide hydrochloride. Encainide hydrochloride, formerly marketed as Enkaid capsules, was associated with increased death rates in patients who had asymptomatic heart rhythm abnormalities after a recent heart attack. The manufacturer of Enkaid capsules voluntarily withdrew the product from the US market on December 16, 1991.
Approved
Investigational
Withdrawn
Matched Synonyms: … (±)-2'-[2-(1-methyl-2-piperidyl)ethyl]-p-anisanilide ... 4-methoxy-2'-[2-(1-methyl-2-piperidyl)ethyl]benzanilide ... (±)-4-methoxy-N-(2-(2-(1-methyl-2-piperidinyl)ethyl)phenyl)benzamide …
Matched Iupac: … 4-methoxy-N-{2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl}benzamide …
Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell...
Approved
Investigational
Vet approved
Matched Synonyms: … (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalene methanamine ... (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamine …
Matched Iupac: … [(2E)-6,6-dimethylhept-2-en-4-yn-1-yl](methyl)[(naphthalen-1-yl)methyl]amine …
Matched Mixtures name: … Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% ... Ciclopirox 8% / Fluconazole 1% / Terbinafine HCl 1% ... M-FURO MANT % 0.1 + % 1 KREM, 20G …
Matched Products: … ERBINOL % 1 KREM ,1 TÜP ... LAMISIL 1% ... FUNGIFEET 1% LOCION (TERBINAFINA CLORHIDRATO 1%) …
Displaying drugs 51 - 75 of 12132 in total