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Displaying drugs 51 - 75 of 2827 in total
Sotorasib, also known as AMG-510, is an acrylamide-derived KRAS inhibitor developed by Amgen.[A187547,A187556] It is indicated in the treatment of adult patients with KRAS G12C mutant non-small cell lung cancer. This mutation makes up >50% of all KRAS mutations. Mutant KRAS discovered in 1982 but was not considered a druggable...
Approved
Investigational
Matched Synonyms: … 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-(1M)-1-[4-methyl-2-(propan-2-yl)pyridin-3-yl]-4-[(2S)-2- methyl …
Matched Iupac: … 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(propan-2-yl)pyridin-3-yl]-4-[(2S)-2-methyl-4-(prop …
Ceftaroline fosamil is a cephalosporin antibacterial indicated for the treatment of the following infections caused by designated susceptible bacteria: Acute bacterial skin and skin structure infections. Community-acquired bacterial pneumonia.
Approved
Investigational
Matched Synonyms: … (6R,7R)-7-[(2Z)-2-ethoxyimino-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-3-[4-(1-methylpyridin …
Matched Iupac: … 4-(2-{[(6R,7R)-2-carboxylato-7-[(2Z)-2-(ethoxyimino)-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetamido …
Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Investigational
Matched Mixtures name: … RISEPLUS D3 35 MG/5600 IU EFERVESAN TABLET, 4 ADET ... RISEPLUS D3 35 MG/2800 IU EFERVESAN TABLET, 12 ADET ... RISEPLUS D3 35 MG/5600 IU EFERVESAN TABLET, 12 ADET …
Matched Products: … RISEDRONATO 35 MG ... ACTONEL ONCE-A-WEEK (35 MG) ... ACTONEL ONCE-A-WEEK TABLET 35 mg …
Valrubicin (N-trifluoroacetyladriamycin-14-valerate) is a chemotherapy drug commonly marketed under the trade name VALSTAR. It is a semisynthetic analog of the doxorubicin, which is an anthracycline drug. Used in the treatment of the bladder cancer, valrubicin is administered by direct infusion into the bladder.
Approved
Matched Synonyms: … 2-oxo-2-[(2S,4S)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-4-({2,3,6-trideoxy-3-[(trifluoroacetyl)amino] …
Matched Iupac: … )-2,5,12-trihydroxy-4-{[(2R,4S,5S,6S)-5-hydroxy-6-methyl-4-(2,2,2-trifluoroacetamido)oxan-2-yl]oxy}-7- …
Blinatumomab is a BiTE-class (bi-specific T-cell engager) constructed monoclonal antibody formed by the recombinant fusion of an anti-CD3 single-chain variable fragment (scFV) and an anti-CD19 scFV through a short peptide linker.[A254836,L44311] CD3 is an antigen expressed on the surface of T-cells, while CD19 is mostly expressed on the surface of...
Approved
Investigational
Matched Products: … BLINCYTO POWDER FOR INFUSION 35 MCG/VIAL ... BLINCYTO (Blinatumomab) for injection 35 mcg/vial …
Calfactant is a sterile, non-pyrogenic lung surfactant intended for intratracheal instillation. It is an off-white suspension of an extract of natural surfactant from calf lungs suspended in 0.9% saline. Each milliliter of calfactant contains 35mg of phospholipids (including 26 mg phosphatidylcholine of which 16 mg is disaturated phosphatidylcholine) and 0.65mg...
Approved
Matched Products: … INFASURF 35 MG/ML INTRATRAKEAL SÜSPANSIYON,3 ML ... INFASURF 35 MG/ML INTRATRAKEAL SÜSPANSIYON ,6 ML …
An antibiotic similar to flucloxacillin used in resistant staphylococci infections.
Approved
Investigational
Matched Synonyms: … (2S,5R,6R)-3,3-dimethyl-6-{[(5-methyl-3-phenylisoxazol-4-yl)carbonyl]amino}-7-oxo-4-thia-1-azabicyclo …
Matched Iupac: … (2S,5R,6R)-3,3-dimethyl-6-(5-methyl-3-phenyl-1,2-oxazole-4-amido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane …
Magnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can be extracted from brine or sea water.
Approved
Matched Mixtures name: … Aminosyn II 7% M In 10% Dextrose(dual Chamber) ... ACCUSOL 35 ... Normocarb 35
Matched Products: … Magnesium-35 0.5 - 4.5 ... Magnesium-35 0.25 - 4.5 …
Approved
Experimental
Matched Products: … FITOFLAVONA® 35 MG …
Norethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19-nortestosterone-derived class of progestins. It is further classified as a second-generation progestin, along with levonorgestrel and its derivatives, and is the active form of several other progestins including norethynodrel and lynestrenol. Norethisterone mimics the actions of endogenous...
Approved
Matched Iupac: … -1-hydroxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7- …
Matched Mixtures name: … Necon 1/35 ... Ovcon 35 ... Ovcon 35
Miconazole is a broad-spectrum azole antifungal with some activity against Gram-positive bacteria as well. It is widely used to treat mucosal yeast infections, including both oral and vaginal infections; although intravenous miconazole is no longer available, a wide variety of suppositories, creams, gels, and tablet-based products are available.[L14021, L14024, L14027,...
Approved
Investigational
Vet approved
Matched Salts cas: … 22832-87-7
Matched Mixtures name: … Monistat 7 Combination Pack 7-Day Pre-Filled Applicators ... Monistat 7 Combination Pack 7-Day Pre-Filled Applicators ... Monistat 7 Combination Pack 7-Day Pre-Filled Applicators …
Matched Products: … Monistat 7 7-Day Disposable Applicators ... Monistat 7 7-day Disposable Applicators ... Miconazole 7
Gemifloxacin is a quinolone antibacterial agent with a broad-spectrum activity that is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. It is available in oral formulations. Gemifloxacin acts by inhibiting DNA synthesis through the inhibition of both DNA gyrase and topoisomerase IV, which are...
Approved
Investigational
Matched Iupac: … 7-[(4Z)-3-(aminomethyl)-4-(methoxyimino)pyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8 …
Matched Products: … ONFACT 320 MG FİLM TABLET, 7 ADET ... FACTIVE 320 MG FİLM TABLET, 7 ADET ... GEMİLOKS 320 MG FİLM KAPLI TABLET, 7 ADET …
Brivudine is used in the treatment of herpes zoster. Although not approved in the U.S. or Canada, it is approved in several European countries.
Approved
Investigational
Matched Products: … ZOSTEX 125 MG TABLET, 7 ADET ... ZONUDIN 125 MG TABLET, 7 ADET …
Trametinib is an orally bioavailable mitogen-activated extracellular signal-regulated kinase 1 (MEK1) and MEK2 inhibitor.[A258298,A258293] It was first approved by the FDA in May 2013 for the treatment of melanoma. It was later approved by Health Canada on July 18, 2013 and by the European Commission on June 30, 2014. Trametinib...
Approved
Matched Products: … MEKINIST 2 MG FILM KAPLI TABLET ,7 TABLET ... MEKINIST 0.5 MG FILM KAPLI TABLET ,7 TABLET …
Anakinra is a recombinant human interleukin-1 (IL-1) receptor antagonist (IL-1Ra) composed of 153 amino acid residues. Unlike native human IL-1Ra, anakinra has an additional methionine residue at the amino terminus. This drug binds to the IL-1 receptor, competing with and inhibiting the activity of IL-1 alpha and beta. Anakinra is...
Approved
Investigational
Matched Products: … Kıneret 100 mg/ 0.67 ml Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Enjektör, 7 ADET …
An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory drugs like acetylsalicylic acid, which is active in inflammatory bowel disease . Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stability as a pharmaceutical...
Approved
Matched Products: … PENTASA 1 G ENEMA,7 ADET ... ASAZİN 4 G/60 G REKTAL SÜSPANSİYON, 7 ADET ... OSİREC 4 G/60 ML REKTAL SÜSPANSİYON, 7 ADET …
Hydromorphone is a pure opioid, a semi-synthetic hydrogenated ketone derivative of morphine that has been available clinically since 1920. Structurally, hydromorphone derived from morphine in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and...
Approved
Illicit
Matched Iupac: … 1S,5R,13R,17R)-10-hydroxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7( …
Matched Description: … the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7
Matched Salts cas: … 25333-57-7
Matched Products: … JURNISTA 4 MG UZATILMIŞ SALIMLI TABLET, 35 ADET ... JURNISTA 4 MG UZATILMIŞ SALIMLI TABLET, 7 ADET ... JURNISTA 8 MG UZATILMIŞ SALIMLI TABLET, 7 ADET …
Titanium dioxide, also known as titanium(IV) oxide or titania, is the naturally occurring oxide of titanium. It is used as a pigment under the names titanium white, Pigment White 6 (PW6), or CI 77891. It is typically extracted from ilmenite, rutile and anatase.
Approved
Matched Mixtures name: … Cellromax 7 Signature CC Cream ... Cellromax 7 Signature CC Cream ... Creme De Jour Multi-action SPF 7
Matched Products: … cle de peau BEAUTE CONCEALER N 7 ... Pure Finish Mineral Powder Foundation SPF 20 Pure Finish 7 ... Yanbal Polvos Compactos Pressed Sunscreen SPF 12 Tono 6-7
Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through...
Approved
Vet approved
Matched Mixtures name: … Aminosyn II 7% With 50% Dextrose ... Aminosyn II 7% With 10% Dextrose ... Aminosyn II 7% M In 10% Dextrose(dual Chamber) …
Matched Products: … Dextrose-35 6.66 - 4.5 ... Dextrose-35 5.55 - 4.5 …
Cladribine is a purine analogue or a chlorinated derivative of adenine that causes apoptosis of B and T lymphocytes. Cladribine was first approved in the United States in 1993 initially as a treatment for a number of hematological malignancies; currently, it is approved for the treatment of hairy cell leukemia....
Approved
Investigational
Matched Products: … MAVENCLAD 10 MG TABLET, 7 ADET …
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
Approved
Matched Products: … NICOLESS 7 MG/DIA PARCHETRASDERMICO ... Nicoderm Trd 36mg Nicotine/7 Sqcm Patch ... NIQUITIN PARCHE TRANSDERMICO 7 MG. ETAPA 3 …
Octinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize DNA photodamage. It was originally developed in 1950's as an organic UV-B filter that absorbs UV-B rays from sun. It is often combined with nanoparticles or other water-resistant liposomes in formulations to increase...
Approved
Investigational
Matched Mixtures name: … Cellromax 7 Signature CC Cream ... Cellromax 7 Signature CC Cream ... Creme De Jour Multi-action SPF 7
Matched Products: … Vitalumiere Moisture-rich Radiance Sunscreen Fluid Makeup, Broad Spectrum SPF 15, 35 Soft Bisque ... Lbel Replenishing Foundation SPF 14 (medium 7) - Brown ... Lbel Filling Effect Foundation SPF 10 (medium 7) - Brown …
Roxithromycin is a semi-synthethic macrolide antibiotic that is structurally and pharmacologically similar to erythromycin, azithromycin, or clarithromycin. It was shown to be more effective against certain Gram-negative bacteria, particularly Legionella pneumophila. Roxithromycin exerts its antibacterial action by binding to the bacterial ribosome and interfering with bacterial protein synthesis. It is...
Approved
Investigational
Withdrawn
Matched Products: … ROKSOLIT 300 MG FİLM TABLET, 7 ADET ... RULID 300 MG FILM TABLET, 7 ADET …
Lenalidomide (previously referred to as CC-5013) is an immunomodulatory drug with potent antineoplastic, anti-angiogenic, and anti-inflammatory properties. It is a 4-amino-glutamyl analogue of thalidomide and like thalidomide, lenalidomide exists as a racemic mixture of the active S(-) and R(+) forms. However, lenalidomide is much safer and potent than thalidomide, with...
Approved
Matched Products: … RIVELIME 5 MG SERT KAPSÜL,7 ADET ... PAUSED 5 MG SERT KAPSÜL , 7 ADET ... LENATU 5 MG SERT KAPSÜL , 7 ADET …
Histamine H1 antagonist with pronounced sedative properties. It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism.
Approved
Vet approved
Matched Salts cas: … 562-10-7
Matched Mixtures name: … 7 Select Night Time Relief ... 7 Select Night Time Relief ... Cold and Flu Nighttime Severe, 24-7 Life …
Matched Products: … 7 Select Sleep Aid …
Displaying drugs 51 - 75 of 2827 in total