Displaying drugs 76 - 100 of 13339 in total
Dyclonine
Dyclonine is an oral anaesthetic found in Sucrets, an over the counter throat lozenge. It may also be found in some Cepacol sore throat spray products.
Approved
Matched Synonyms: … 1-(4-Butoxyphenyl)-3-(1-piperidinyl)-1-propanone ... 3-piperidino-4'-butoxypropiophenone ... 4'-butoxy-3-piperidinopropiophenone …
Matched Iupac: … 1-(4-butoxyphenyl)-3-(piperidin-1-yl)propan-1-one …
Matched Iupac: … 1-(4-butoxyphenyl)-3-(piperidin-1-yl)propan-1-one …
Norfloxacin
A synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA gyrase.
Approved
Matched Synonyms: … 1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsäure ... 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid ... 1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid …
Matched Iupac: … 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … A synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most …
Matched Iupac: … 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … A synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most …
Rofecoxib
Rofecoxib is used for the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and primary dysmenorrhea, as well as acute treatment of migraine attacks with or without auras. Rofecoxib is a solid. This compound belongs to the stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 )...
Approved
Investigational
Withdrawn
Matched Synonyms: … 3-phenyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone ... 4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanone …
Matched Iupac: … 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one …
Matched Description: … 1A2, Cytochrome P450 3A4, Cytochrome P450 2C9, Cytochrome P450 2C8, and Prostaglandin G/H synthase 1 ... Rofecoxib is a solid. This compound belongs to the stilbenes. ... These are organic compounds containing a 1,2-diphenylethylene moiety. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one …
Matched Description: … 1A2, Cytochrome P450 3A4, Cytochrome P450 2C9, Cytochrome P450 2C8, and Prostaglandin G/H synthase 1 ... Rofecoxib is a solid. This compound belongs to the stilbenes. ... These are organic compounds containing a 1,2-diphenylethylene moiety. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ofloxacin
A synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Approved
Matched Synonyms: … 8-Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic …
Matched Iupac: … 7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13), …
Matched Description: … A synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity …
Matched Products: … MENEFLOKS IV 200 MG/100 ML IV İNFÜZYONLUK ÇÖZELTİ, 1 ADET ... Floxal 3 mg/g Augensalbe ... VisioFlox 3 mg/g Augensalbe …
Matched Iupac: … 7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13), …
Matched Description: … A synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity …
Matched Products: … MENEFLOKS IV 200 MG/100 ML IV İNFÜZYONLUK ÇÖZELTİ, 1 ADET ... Floxal 3 mg/g Augensalbe ... VisioFlox 3 mg/g Augensalbe …
Cyclothiazide
As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides like cyclothiazide also inhibit sodium ion transport across the renal tubular epithelium through binding to the thiazide sensitive sodium-chloride transporter....
Approved
Matched Synonyms: … 6-chloro-3-(2-norbornen-5-yl)-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide ... 6-chloro-3,4-dihydro-3-(2-norbornen-5-yl)-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide ... 6-chloro-3,4-dihydro-3-(2-norbornen-5-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide …
Matched Iupac: … 3-{bicyclo[2.2.1]hept-5-en-2-yl}-6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Matched Description: … As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the …
Matched Iupac: … 3-{bicyclo[2.2.1]hept-5-en-2-yl}-6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Matched Description: … As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the …
Methotrimeprazine
A phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine. It has the histamine-antagonist properties of the antihistamines together with central nervous system effects resembling those of chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed, p604)
Approved
Investigational
Matched Synonyms: … (-)-(2R)-3-(2-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine ... (-)-10-(3-(Dimethylamino)-2-methylpropyl)-2-methoxyphenothiazine …
Matched Iupac: … [(2R)-3-(2-methoxy-10H-phenothiazin-10-yl)-2-methylpropyl]dimethylamine …
Matched Description: … A phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine …
Matched Salts cas: … 1236-99-3 ... 7104-38-3 …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 3-Ring …
Matched Iupac: … [(2R)-3-(2-methoxy-10H-phenothiazin-10-yl)-2-methylpropyl]dimethylamine …
Matched Description: … A phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine …
Matched Salts cas: … 1236-99-3 ... 7104-38-3 …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 3-Ring …
Seladelpar
Seladelpar is a peroxisome proliferator-activated receptor (PPAR)-delta (δ) agonist. Seladelpar is a single enantiomer of the R-configuration. On August 14, 2024, seladelpar was granted accelerated approval by the FDA for the treatment of primary biliary cholangitis, which is a condition associated with aberrant bile acid metabolism. Seladelpar works to block...
Approved
Investigational
Matched Synonyms: … ((4-(((2R)-2-ETHOXY-3-(4-(TRIFLUOROMETHYL)PHENOXY)PROPYL)THIO)-2-METHYLPHENYL)OXY)ACETIC ACID ... )-2-ETHOXY-3-(4-(TRIFLUOROMETHYL)PHENOXY)PROPYL)THIO)-2-METHYLPHENYL)OXY)ACETIC ACID ... (R)-2-(4-((2-ETHOXY-3-(4-(TRIFLUOROMETHYL)PHENOXY)PROPYL)-THIO)-2-METHYLPHENOXY)ACETIC ACID …
Matched Iupac: … 2-(4-{[(2R)-2-ethoxy-3-[4-(trifluoromethyl)phenoxy]propyl]sulfanyl}-2-methylphenoxy)acetic acid …
Matched Description: … Seladelpar is a single enantiomer of the R-configuration. ... Seladelpar is a peroxisome proliferator-activated receptor (PPAR)-delta (δ) agonist. ... accelerated approval by the FDA for the treatment of primary biliary cholangitis,[L51154] which is a …
Matched Salts cas: … 928821-40-3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 2-(4-{[(2R)-2-ethoxy-3-[4-(trifluoromethyl)phenoxy]propyl]sulfanyl}-2-methylphenoxy)acetic acid …
Matched Description: … Seladelpar is a single enantiomer of the R-configuration. ... Seladelpar is a peroxisome proliferator-activated receptor (PPAR)-delta (δ) agonist. ... accelerated approval by the FDA for the treatment of primary biliary cholangitis,[L51154] which is a …
Matched Salts cas: … 928821-40-3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Testosterone enantate benzilic acid hydrazone
Approved
Experimental
Matched Synonyms: … Testosterone 17-enanthate 3-benzilic acid hydrazone …
Matched Iupac: … phenanthren-1-yl heptanoate ... diphenylacetamido)imino]-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Iupac: … phenanthren-1-yl heptanoate ... diphenylacetamido)imino]-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Perphenazine
An antipsychotic phenothiazine derivative with actions and uses similar to those of chlorpromazine.
Approved
Matched Synonyms: … 4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperazineethanol ... 2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol ... 4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol …
Matched Iupac: … 2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethan-1-ol …
Matched Mixtures name: … Etrafon A Tab ... Apo Peram Tab 3-15 ... PMS-levazine 3/15 Tab …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Iupac: … 2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethan-1-ol …
Matched Mixtures name: … Etrafon A Tab ... Apo Peram Tab 3-15 ... PMS-levazine 3/15 Tab …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Phenmetrazine
A sympathomimetic drug used primarily as an appetite depressant. Its actions and mechanisms are similar to dextroamphetamine.
Approved
Illicit
Matched Synonyms: … 2-phenyl-3-methylmorpholine …
Matched Iupac: … 3-methyl-2-phenylmorpholine …
Matched Description: … A sympathomimetic drug used primarily as an appetite depressant. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 3-methyl-2-phenylmorpholine …
Matched Description: … A sympathomimetic drug used primarily as an appetite depressant. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Cloxacillin
A semi-synthetic penicillin antibiotic which is a chlorinated derivative of oxacillin.
Approved
Investigational
Vet approved
Matched Synonyms: … (2S,5R,6R)-6-({[3-(2-chlorophenyl)-5-methylisoxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1- ... (3-(o-chlorophenyl)-5-methyl-4-isoxazolyl)penicillin ... 6-(3-(o-chlorophenyl)-5-methyl-4-isoxazolecarboxamido)penicillanic acid …
Matched Iupac: … (2S,5R,6R)-6-[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo …
Matched Description: … A semi-synthetic penicillin antibiotic which is a chlorinated derivative of [oxacillin]. …
Matched Iupac: … (2S,5R,6R)-6-[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-amido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo …
Matched Description: … A semi-synthetic penicillin antibiotic which is a chlorinated derivative of [oxacillin]. …
Buprenorphine
Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain.[A186283,A186292] It is also commonly used as an alternative to methadone for the treatment of severe opioid addiction. Buprenorphine is commercially available as the brand name product Suboxone which is...
Approved
Illicit
Investigational
Vet approved
Matched Synonyms: … -3-ol ... 17-cyclopropylmethyl-4,5α-epoxy-7α-((S)-1-hydroxy-1,2,2-trimethylpropyl)-6-methoxy-6,14-endo-ethanomorphinan ... 2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(14R)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12 …
Matched Iupac: … -oxa-3-azahexacyclo[13.2.2.1^{2,8}.0^{1,6}.0^{6,14}.0^{7,12}]icosa-7,9,11-trien-11-ol ... (1S,2R,6S,14R,15R,16R)-3-(cyclopropylmethyl)-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13 …
Matched Description: … 4:1 fixed-dose combination product along with [naloxone], a non-selective competitive opioid receptor ... Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist ... Buprenorphine has a number of unique pharmacokinetic and pharmacodynamic properties that make it a preferred …
Matched Mixtures name: … Bupensan Duo 4 mg/1 mg-Sublingualtabletten …
Matched Products: … Bupensan 1 mg-Sublingualtabletten …
Matched Iupac: … -oxa-3-azahexacyclo[13.2.2.1^{2,8}.0^{1,6}.0^{6,14}.0^{7,12}]icosa-7,9,11-trien-11-ol ... (1S,2R,6S,14R,15R,16R)-3-(cyclopropylmethyl)-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13 …
Matched Description: … 4:1 fixed-dose combination product along with [naloxone], a non-selective competitive opioid receptor ... Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist ... Buprenorphine has a number of unique pharmacokinetic and pharmacodynamic properties that make it a preferred …
Matched Mixtures name: … Bupensan Duo 4 mg/1 mg-Sublingualtabletten …
Matched Products: … Bupensan 1 mg-Sublingualtabletten …
Chlormezanone
A non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.
Approved
Investigational
Withdrawn
Matched Synonyms: … 2-(p-chlorphenyl)-3-methyl-1,3-perhydrothiazin-4-on-1,1-dioxide ... 2-(p-chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one 1,1-dioxide …
Matched Iupac: … 2-(4-chlorophenyl)-3-methyl-1lambda6,3-thiazinane-1,1,4-trione …
Matched Description: … A non-benzodiazepine that is used in the management of anxiety. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 2-(4-chlorophenyl)-3-methyl-1lambda6,3-thiazinane-1,1,4-trione …
Matched Description: … A non-benzodiazepine that is used in the management of anxiety. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Amlodipine
Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities...
Approved
Matched Synonyms: … (RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate ... 3-Ethyl 5-methylester, (±)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate …
Matched Iupac: … 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the ... selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a …
Matched Mixtures name: … CARDIK®3 160/10/12.5 ... CARDIK®3 160/10/12.5 ... CARDIK ® 3 160/5/12.5 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … PRESONE-1 ... A-B VASK 5 ... A-B VASK 10 …
Matched Iupac: … 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the ... selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a …
Matched Mixtures name: … CARDIK®3 160/10/12.5 ... CARDIK®3 160/10/12.5 ... CARDIK ® 3 160/5/12.5 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … PRESONE-1 ... A-B VASK 5 ... A-B VASK 10 …
Dezocine
Dezocine is a partial opiate drug and is used for pain management. Dezocine is a very effective alternative to fentanyl when administered during outpatient laparoscopy, although is associated with an increased incidence of postoperative nausea.
Approved
Investigational
Matched Synonyms: … (−)-13β-amino-5,6,7,8,9,10,11α,12-octahydro-5α-methyl-5,11-methanobenzocyclodecen-3-ol …
Matched Iupac: … (1R,9S,15S)-15-amino-1-methyltricyclo[7.5.1.0^{2,7}]pentadeca-2,4,6-trien-4-ol …
Matched Description: … Dezocine is a partial opiate drug and is used for pain management. ... Dezocine is a very effective alternative to fentanyl when administered during outpatient laparoscopy, …
Matched Iupac: … (1R,9S,15S)-15-amino-1-methyltricyclo[7.5.1.0^{2,7}]pentadeca-2,4,6-trien-4-ol …
Matched Description: … Dezocine is a partial opiate drug and is used for pain management. ... Dezocine is a very effective alternative to fentanyl when administered during outpatient laparoscopy, …
Aminoglutethimide
An aromatase inhibitor that produces a state of "medical" adrenalectomy by blocking the production of adrenal steroids. It also blocks the conversion of androgens to estrogens. Aminoglutethimide has been used in the treatment of advanced breast and prostate cancer. It was formerly used for its weak anticonvulsant properties. (From Martindale,...
Approved
Investigational
Matched Synonyms: … 3-Ethyl-3-(p-aminophenyl)-2,6-dioxopiperidine …
Matched Iupac: … 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione …
Matched Description: … An aromatase inhibitor that produces a state of "medical" adrenalectomy by blocking the production of …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione …
Matched Description: … An aromatase inhibitor that produces a state of "medical" adrenalectomy by blocking the production of …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
PBT-434
Approved
Investigational
Matched Synonyms: … 5,7-dichloro-2-((ethylamino)methyl)-8-hydroxy-3-methylquinazolin-4(3h)-one …
Matched Iupac: … 5,7-dichloro-2-[(ethylamino)methyl]-8-hydroxy-3-methyl-3,4-dihydroquinazolin-4-one …
Matched Iupac: … 5,7-dichloro-2-[(ethylamino)methyl]-8-hydroxy-3-methyl-3,4-dihydroquinazolin-4-one …
Mavacamten
Mavacamten is a myosin inhibitor indicated for the treatment of adults with symptomatic New York Heart Association (NYHA) class II-III obstructive hypertrophic cardiomyopathy (HCM). It received initial US FDA approval in 2022, and it is one of the first myosin inhibitors to be used in humans. Mavacamten was also approved...
Approved
Investigational
Matched Synonyms: … 6-(((1S)-1-Phenylethyl)amino)-3-(propan-2-yl)-1,2,3,4 tetrahydropyrimidine-2,4-dione …
Matched Iupac: … 6-{[(1S)-1-phenylethyl]amino}-3-(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … Mavacamten is a myosin inhibitor indicated for the treatment of adults with symptomatic New York Heart …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 6-{[(1S)-1-phenylethyl]amino}-3-(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … Mavacamten is a myosin inhibitor indicated for the treatment of adults with symptomatic New York Heart …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Chlorpheniramine
A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine.
Approved
Matched Synonyms: … 1-(p-chlorophenyl)-1-(2-pyridyl)-3-dimethylaminopropane ... 1-(p-chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpropylamine ... 3-(p-chlorophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine …
Matched Iupac: … [3-(4-chlorophenyl)-3-(pyridin-2-yl)propyl]dimethylamine …
Matched Description: … A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. …
Matched Mixtures name: … A-FERİN 1 MG +160 MG/5 ML PEDİYATRİK ŞURUP, 100 ML ... XL-3 Cold ... XL-3 Xtra …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … ALERFIN 2 MG/5 ML ORAL ÇÖZELTI, 1 ŞIŞE …
Matched Iupac: … [3-(4-chlorophenyl)-3-(pyridin-2-yl)propyl]dimethylamine …
Matched Description: … A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. …
Matched Mixtures name: … A-FERİN 1 MG +160 MG/5 ML PEDİYATRİK ŞURUP, 100 ML ... XL-3 Cold ... XL-3 Xtra …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … ALERFIN 2 MG/5 ML ORAL ÇÖZELTI, 1 ŞIŞE …
Dexlansoprazole
Dexlansoprazole is a new-generation proton pump inhibitor (PPI) used for the management of symptoms associated with gastroesophageal reflux disease (GERD) and erosive esophagitis. Dexlansoprazole is the R-enantiomer of DB00448, which is composed of a racemic mixture of the R- and S-enantiomers. Compared to the older generation of PPIs (which includes...
Approved
Investigational
Matched Synonyms: … (+)-2-((R)-((3-METHYL-4-(2,2,2-TRIFLUOROETHOXY)PYRIDIN-2-YL)METHYL)SULFINYL)-1H-BENZIMIDAZOLE ... 1H-BENZIMIDAZOLE, 2-((R)-((3-METHYL-4-(2,2,2-TRIFLUOROETHOXY)-2-PYRIDINYL)METHYL)SULFINYL)- ... 2-((R)-((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole …
Matched Iupac: … 2-[(R)-[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methanesulfinyl]-1H-1,3-benzodiazole …
Matched Description: … Dexlansoprazole is a new-generation proton pump inhibitor (PPI) used for the management of symptoms associated ... Dexlansoprazole is the R-enantiomer of [DB00448], which is composed of a racemic mixture of the R- and ... generation of PPIs (which includes [DB00213], [DB00338], and [DB00448]),[A178084] dexlansoprazole has a …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 2-[(R)-[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methanesulfinyl]-1H-1,3-benzodiazole …
Matched Description: … Dexlansoprazole is a new-generation proton pump inhibitor (PPI) used for the management of symptoms associated ... Dexlansoprazole is the R-enantiomer of [DB00448], which is composed of a racemic mixture of the R- and ... generation of PPIs (which includes [DB00213], [DB00338], and [DB00448]),[A178084] dexlansoprazole has a …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Clidinium
Clidinium is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. It inhibits muscarinic actions of acetylcholine at postganglionic parasympathetic neuroeffector sites. It is used for the treatment of peptic ulcer disease and also...
Approved
Matched Synonyms: … 3-(2-Hydroxy-2,2-diphenyl-acetoxy)-1-methyl-1-azonia-bicyclo[2.2.2]octane ... 3-hydroxy-1-methylquinuclidinium benzilate ester …
Matched Iupac: … (1s,4s)-3-[(2-hydroxy-2,2-diphenylacetyl)oxy]-1-methyl-1-azabicyclo[2.2.2]octan-1-ium …
Matched Description: … to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. ... Clidinium is a synthetic anticholinergic agent which has been shown in experimental and clinical studies …
Matched Iupac: … (1s,4s)-3-[(2-hydroxy-2,2-diphenylacetyl)oxy]-1-methyl-1-azabicyclo[2.2.2]octan-1-ium …
Matched Description: … to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. ... Clidinium is a synthetic anticholinergic agent which has been shown in experimental and clinical studies …
Lenvatinib
Lenvatinib is a receptor tyrosine kinase (RTK) inhibitor that inhibits the kinase activities of vascular endothelial growth factor (VEGF) receptors VEGFR1 (FLT1), VEGFR2 (KDR), and VEGFR3 (FLT4). Lenvatinib also inhibits other RTKs that have been implicated in pathogenic angiogenesis, tumor growth, and cancer progression in addition to their normal cellular...
Approved
Investigational
Matched Synonyms: … 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide …
Matched Iupac: … 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide …
Matched Description: … addition to their normal cellular functions, including fibroblast growth factor (FGF) receptors FGFR1, 2, 3, ... Lenvatinib is a receptor tyrosine kinase (RTK) inhibitor that inhibits the kinase activities of vascular ... and increased expression of VEGF is associated with a poor prognosis in many types of cancers. …
Matched Salts cas: … 857890-39-2 …
Matched Iupac: … 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide …
Matched Description: … addition to their normal cellular functions, including fibroblast growth factor (FGF) receptors FGFR1, 2, 3, ... Lenvatinib is a receptor tyrosine kinase (RTK) inhibitor that inhibits the kinase activities of vascular ... and increased expression of VEGF is associated with a poor prognosis in many types of cancers. …
Matched Salts cas: … 857890-39-2 …
Sorafenib
Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated in tumour cell proliferation and tumour angiogenesis. First approved by the FDA and European Commission in 2007 for the treatment of hepatocellular carcinoma, sorafenib is also...
Approved
Investigational
Matched Synonyms: … N-(4-Chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea ... 4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide …
Matched Iupac: … 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide …
Matched Description: … Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. …
Matched Salts cas: … 475207-59-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... UGT1A9 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide …
Matched Description: … Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. …
Matched Salts cas: … 475207-59-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... UGT1A9 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index …
Norgestrel
Norgestrel is synthetic steroidal progestin that is used in combination with ethinyl estradiol for oral contraception. Norgestrel is composed of a racemic mixture of two stereoisomers, dextronorgestrel and levonorgestrel. However, only the levorotary enantiomer (levonorgestrel) is biologically active.
Approved
Matched Synonyms: … 17-ethynyl-17-hydroxy-18a-homoestr-4-en-3-one …
Matched Description: … Norgestrel is composed of a racemic mixture of two stereoisomers, dextronorgestrel and levonorgestrel …
Matched Description: … Norgestrel is composed of a racemic mixture of two stereoisomers, dextronorgestrel and levonorgestrel …
Aminophenazone
Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties that carries a risk of agranulocytosis. In biomedical applications, radiolabelled (13C-labeled) aminophenazone has been used in breath tests to measure the cytochrome P-450 metabolic activity in liver function tests. The FDA suspended the use of aminophenazone due to its association...
Approved
Withdrawn
Matched Synonyms: … 4-Dimethylamino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one ... 1,5-Dimethyl-4-dimethylamino-2-phenyl-3-pyrazolone ... 3-Keto-1,5-dimethyl-4-dimethylamino-2-phenyl-2,3-dihydropyrazole …
Matched Iupac: … 4-(dimethylamino)-1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one …
Matched Description: … a risk of agranulocytosis. ... Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties that carries ... The FDA suspended the use of aminophenazone due to its association with agranulocytosis, a life-threatening …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 4-(dimethylamino)-1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one …
Matched Description: … a risk of agranulocytosis. ... Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties that carries ... The FDA suspended the use of aminophenazone due to its association with agranulocytosis, a life-threatening …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 76 - 100 of 13339 in total