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Displaying drugs 76 - 100 of 8459 in total
Haloperidol
Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently used antipsychotic medications used worldwide. While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain, it exerts its antipsychotic effect through its strong antagonism of the dopamine receptor (mainly D2), particularly within...
Approved
Matched Synonyms: … 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)-butan-1-one ... 1-(3-p-fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine …
Matched Iupac: … 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one …
Matched Products: … DORES 1,5 ... NORODOL 1,5 MG TABLET, 50 ADET ... HALOPERIDOL 5 MG / 1 ML …
Matched Iupac: … 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one …
Matched Products: … DORES 1,5 ... NORODOL 1,5 MG TABLET, 50 ADET ... HALOPERIDOL 5 MG / 1 ML …
Loracarbef
Loracarbef is a carbacephem antibiotic sometimes grouped together with the second-generation cephalosporin antibiotics. It is marketed under the trade name Lorabid.
Approved
Investigational
Withdrawn
Matched Iupac: … (6R,7S)-7-[(2R)-2-amino-2-phenylacetamido]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Cinoxacin
Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections.
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-ethyl-6,7-methylenedioxy-4(1H)-oxocinnoline-3-carboxylic acid ... 5-Ethyl-8-oxo-5,8-dihydro-1,3-dioxa-5,6-diaza-cyclopenta[b]naphthalene-7-carboxylic acid …
Matched Iupac: … 1-ethyl-4-oxo-1H,4H,7H-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid …
Matched Iupac: … 1-ethyl-4-oxo-1H,4H,7H-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid …
Cimetidine
A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Approved
Investigational
Matched Synonyms: … 1-Cyano-2-methyl-3-(2-(((5-methyl-4-imidazolyl)methyl)thio)ethyl)guanidine ... 2-cyano-1-methyl-3-(2-(((5-methylimidazol-4-yl)methyl)thio)ethyl)guanidine ... N''-cyano-N-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine …
Matched Iupac: … (Z)-N''-cyano-N-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine …
Matched Mixtures name: … Cimetidine 10% / Lidocaine 5% / Salicylic Acid 40% ... Cimetidine 5% / Ibuprofen 2% / Salicylic Acid 17% …
Matched Categories: … MATE 1 Inhibitors ... MATE 1 Substrates ... Heterocyclic Compounds, 1-Ring …
Matched Products: … Cimetidine in Sodium Chloride …
Matched Iupac: … (Z)-N''-cyano-N-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine …
Matched Mixtures name: … Cimetidine 10% / Lidocaine 5% / Salicylic Acid 40% ... Cimetidine 5% / Ibuprofen 2% / Salicylic Acid 17% …
Matched Categories: … MATE 1 Inhibitors ... MATE 1 Substrates ... Heterocyclic Compounds, 1-Ring …
Matched Products: … Cimetidine in Sodium Chloride …
Bioallethrin
Bioallethrin refers to a mixture of two of the allethrin isomers (1R,trans;1R and 1R,trans;1S) in an approximate ratio of 1:1, where both isomers are active ingredients. A mixture of the two same stereoisomers, but in an approximate ratio of R:S in 1:3, is called esbiothrin. A mixture containing only S-forms...
Approved
Experimental
Matched Iupac: … 2-methyl-4-oxo-3-(prop-2-en-1-yl)cyclopent-2-en-1-yl 2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane ... -1-carboxylate …
Matched Description: … 1, where both isomers are active ingredients. ... a mixture of two of the allethrin isomers (1R,trans;1R and 1R,trans;1S) in an approximate ratio of 1: ... A mixture of the two same stereoisomers, but in an approximate ratio of R:S in 1:3, is called esbiothrin …
Matched Description: … 1, where both isomers are active ingredients. ... a mixture of two of the allethrin isomers (1R,trans;1R and 1R,trans;1S) in an approximate ratio of 1: ... A mixture of the two same stereoisomers, but in an approximate ratio of R:S in 1:3, is called esbiothrin …
Grepafloxacin
Grepafloxacin is an oral broad-spectrum quinoline antibacterial agent used to treat bacterial infections. Due to the QTc-prolonging potential, as indicated by the changes in the QT interval on the electrocardiogram, and the risk for cardiovascular adverse events, grepafloxacin was withdrawn in the United States.
Approved
Investigational
Withdrawn
Matched Iupac: … 1-cyclopropyl-6-fluoro-5-methyl-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Disopyramide
A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
Approved
Matched Description: … A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac …
Matched Salts cas: … 22059-60-5 …
Matched Categories: … Antiarrhythmics, Class I ... Heterocyclic Compounds, 1-Ring ... Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers …
Matched Salts cas: … 22059-60-5 …
Matched Categories: … Antiarrhythmics, Class I ... Heterocyclic Compounds, 1-Ring ... Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers …
Collagenase clostridium histolyticum
Collagenase clostridium histolyticum is an enzyme produced by the bacterium Clostridium histolyticum. It is beneficial in the breakdown of collagen plaques for the treatment of Dupuytren's contracture and Peyronie's disease. The topical formulation is used for the debridement of necrotic tissue due to burns or chronic ulcers. On July 6,...
Approved
Investigational
Indigotindisulfonic acid
Indigotindisulfonic acid is a blue-colored dye with a variety of uses.[A32490,A32491,A32492,L2222] Its salt form, indigotindisulfonate sodium, is also known as indigo carmine, indigotine or FD&C Blue #2. This compound is an acid-base indicator and is used in the production of food colorants and pH tests. Indigotindisulfonic acid is used in...
Approved
Investigational
Matched Synonyms: … 2-(1,3-Dihydro-3-oxo-5-sulpho-2H-indol-2-ylidene)-3-oxoindoline-5-sulphonic acid …
Matched Iupac: … (E)-3,3'-dioxo-1H,1'H,3H,3'H-[2,2'-biindolylidene]-5,5'-disulfonic acid …
Matched Description: … [A32490,A32491,A32492,L2222] Its salt form, indigotindisulfonate sodium, is also known as indigo carmine ... [A32490,A32491,A32492] In 2022, the FDA approved the intravenous use of indigotindisulfonate sodium to …
Matched Salts name: … Indigotindisulfonate sodium …
Matched Products: … INDIGO CARMINE INJECTION 20 mg/5 ml …
Matched Iupac: … (E)-3,3'-dioxo-1H,1'H,3H,3'H-[2,2'-biindolylidene]-5,5'-disulfonic acid …
Matched Description: … [A32490,A32491,A32492,L2222] Its salt form, indigotindisulfonate sodium, is also known as indigo carmine ... [A32490,A32491,A32492] In 2022, the FDA approved the intravenous use of indigotindisulfonate sodium to …
Matched Salts name: … Indigotindisulfonate sodium …
Matched Products: … INDIGO CARMINE INJECTION 20 mg/5 ml …
Pentoxifylline
Pentoxifylline (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and also has both anti-oxidant and anti-inflammatory properties.[A226415, L30300] Although originally developed to treat intermittent claudication, a form of exertion-induced leg pain common in patients with peripheral arterial disease, PTX has been investigated for its possible...
Approved
Investigational
Matched Iupac: … 3,7-dimethyl-1-(5-oxohexyl)-2,3,6,7-tetrahydro-1H-purine-2,6-dione …
Matched Mixtures name: … Betamethasone Dipropionate 0.05% / Minoxidil 5% / Niacinamide 2% / Pentoxifylline 0.5% …
Matched Categories: … Phosphodiesterase 5 Inhibitors …
Matched Products: … TECXIFIL-I ... ONPENT 100 MG/5 ML İ.V. İNFÜZYONLUK ÇÖZELTİ , 5 ADET ... HEMOPENE 100 MG 5 ML 10 AMPUL …
Matched Mixtures name: … Betamethasone Dipropionate 0.05% / Minoxidil 5% / Niacinamide 2% / Pentoxifylline 0.5% …
Matched Categories: … Phosphodiesterase 5 Inhibitors …
Matched Products: … TECXIFIL-I ... ONPENT 100 MG/5 ML İ.V. İNFÜZYONLUK ÇÖZELTİ , 5 ADET ... HEMOPENE 100 MG 5 ML 10 AMPUL …
Mexiletine
Antiarrhythmic agent pharmacologically similar to lidocaine. It may have some anticonvulsant properties.
Approved
Investigational
Matched Synonyms: … 1-methyl-2-(2,6-xylyloxy)ethanamine ... (±)-1-(2,6-dimethylphenoxy)propan-2-amine ... 1-(2,6-dimethylphenoxy)-2-propanamine …
Matched Iupac: … 1-(2,6-dimethylphenoxy)propan-2-amine …
Matched Categories: … Antiarrhythmics, Class I ... Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers …
Matched Iupac: … 1-(2,6-dimethylphenoxy)propan-2-amine …
Matched Categories: … Antiarrhythmics, Class I ... Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers …
Imipramine
Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, imipramine exerts...
Approved
Matched Synonyms: … 10,11-dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine ... 5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine …
Matched Iupac: … (3-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-yl}propyl)dimethylamine …
Matched Description: … TCAs also block histamine H1 receptors, α1-adrenergic receptors and muscarinic …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists ... Serotonin 5-HT2C Receptor Antagonists …
Matched Iupac: … (3-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-yl}propyl)dimethylamine …
Matched Description: … TCAs also block histamine H1 receptors, α1-adrenergic receptors and muscarinic …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists ... Serotonin 5-HT2C Receptor Antagonists …
Tavaborole
Tavaborale is a novel, boron-based topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed due to Trichophyton rubrum or Trichophyton mentagrophytes infection. Tavaborole functions by inhibiting Leucyl-tRNA synthetase, or LeuRS, an essential fungal enzyme required for protein synthesis and for the catalysis...
Approved
Investigational
Matched Synonyms: … 5-Fluoro-2,1-benzoxaborol-1(3H)-ol ... 5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole …
Matched Iupac: … 5-fluoro-1,3-dihydro-2,1-benzoxaborol-1-ol …
Matched Iupac: … 5-fluoro-1,3-dihydro-2,1-benzoxaborol-1-ol …
Flavin mononucleotide
A coenzyme for a number of oxidative enzymes including NADH DEHYDROGENASE. It is the principal form in which RIBOFLAVIN is found in cells and tissues.
Approved
Investigational
Matched Synonyms: … riboflavin 5'-phosphate ... Riboflavin-5-phosphate ... riboflavin 5'-monophosphate …
Matched Iupac: … {[(2R,3S,4S)-5-{7,8-dimethyl-2,4-dioxo-2H,3H,4H,10H-benzo[g]pteridin-10-yl}-2,3,4-trihydroxypentyl]oxy …
Matched Salts cas: … 130-40-5 ... 130-40-5 …
Matched Mixtures name: … B-KOMP ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL, 5 ADET …
Matched Salts name: … Riboflavin 5'-phosphate sodium anhydrous ... Riboflavin-5'-phosphate sodium salt dihydrate ... Riboflavin sodium phosphate …
Matched Iupac: … {[(2R,3S,4S)-5-{7,8-dimethyl-2,4-dioxo-2H,3H,4H,10H-benzo[g]pteridin-10-yl}-2,3,4-trihydroxypentyl]oxy …
Matched Salts cas: … 130-40-5 ... 130-40-5 …
Matched Mixtures name: … B-KOMP ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL, 5 ADET …
Matched Salts name: … Riboflavin 5'-phosphate sodium anhydrous ... Riboflavin-5'-phosphate sodium salt dihydrate ... Riboflavin sodium phosphate …
Golodirsen
Golodirsen is a morpholino antisense oligomer designed to treat about 8% of patients with Duchenne Muscular Dystrophy (DMD). This is an X-linked condition leading to progressive muscle degeneration that begins in early childhood, rendering many patients wheelchair-bound by age 12. Often, patients succumb to this condition by age 30 or...
Approved
Enalaprilat
Enalaprilat is the active metabolite of the orally available pro-drug, enalapril. Used in the treatment of hypertension, enalapril is an ACE inhibitor that prevents Angiotensin Converting Enzyme (ACE) from transforming angiotensin I into angiotensin II. As angiotensin II is responsible for vasoconstriction and sodium reabsorption in the proximal tubule of...
Approved
Matched Iupac: … (2S)-1-[(2S)-2-{[(1S)-1-carboxy-3-phenylpropyl]amino}propanoyl]pyrrolidine-2-carboxylic acid …
Matched Description: … is an ACE inhibitor that prevents Angiotensin Converting Enzyme (ACE) from transforming angiotensin I ... As angiotensin II is responsible for vasoconstriction and sodium reabsorption in the proximal tubule …
Matched Description: … is an ACE inhibitor that prevents Angiotensin Converting Enzyme (ACE) from transforming angiotensin I ... As angiotensin II is responsible for vasoconstriction and sodium reabsorption in the proximal tubule …
Labetalol
Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up 25% of the mixture. Labetalol is formulated as an injection or tablets to treat hypertension.[L7727,L7730]
Labetalol was granted FDA approval on 1 August 1984.
Approved
Matched Synonyms: … 5-(1-Hydroxy-2-(1-methyl-3-phenylpropylamino)ethyl)salicylamide ... 3-Carboxamido-4-hydroxy-alpha-((1-methyl-3-phenylpropylamino)methyl)benzyl alcohol …
Matched Iupac: … 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide …
Matched Description: … [L7727,L7730] Labetalol was granted FDA approval on 1 August 1984.[L7724] …
Matched Categories: … Peripheral alpha-1 blockers ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … Labetalol HCl in Sodium Chloride ... LABLOL 100 MG/20 ML IV ENJEKSİYONLUK ÇÖZELTİ, 5 ADET ... LABETALOL HIDROCLORURO 5 MG/ML SOLUCIÓN INYECTABLE …
Matched Iupac: … 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide …
Matched Description: … [L7727,L7730] Labetalol was granted FDA approval on 1 August 1984.[L7724] …
Matched Categories: … Peripheral alpha-1 blockers ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … Labetalol HCl in Sodium Chloride ... LABLOL 100 MG/20 ML IV ENJEKSİYONLUK ÇÖZELTİ, 5 ADET ... LABETALOL HIDROCLORURO 5 MG/ML SOLUCIÓN INYECTABLE …
Inositol
Inositol is a collection of nine different stereoisomers but the name is usually used to describe only the most common type of inositol, myo-inositol. Myo-inositol is the cis-1,2,3,5-trans-4,6-cyclohexanehexol and it is prepared from an aqueous extract of corn kernels by precipitation and hydrolysis of crude phytate. These molecules have structural...
Approved
Investigational
Withdrawn
Matched Mixtures name: … Multi Plex I - Tab ... Hoa 1 ... Vege 1 Daily Tab …
Permethrin
A pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. It is a yellow to light orange-brown, low melt-ing solid or viscous liquid.
Approved
Investigational
Matched Iupac: … (3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate …
Matched Products: … NOBIT % 1 ŞAMPUAN ... A-LICES LOTION 1%w/w ... PIO LAD® 1% CHAMPU …
Matched Products: … NOBIT % 1 ŞAMPUAN ... A-LICES LOTION 1%w/w ... PIO LAD® 1% CHAMPU …
Griseofulvin
An antifungal antibiotic. Griseofulvin may be given by mouth in the treatment of tinea infections.
Approved
Investigational
Vet approved
Matched Iupac: … (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H-spiro[1-benzofuran-2,1'-cyclohexan]-2'-ene-3,4'-dione …
Oxytetracycline
A tetracycline analog isolated from the actinomycete streptomyces rimosus and used in a wide variety of clinical conditions.
Approved
Investigational
Vet approved
Matched Synonyms: … 5-Hydroxytetracycline …
Matched Products: … TERRAFUNGIN 50 MG/ML FLAKON, 1 ADET ... TERRAFUNGIN 100 MG/2 ML AMPUL, 1 ADET ... TERRAFUNGIN 250 MG/2 ML AMPUL, 1 ADET …
Matched Products: … TERRAFUNGIN 50 MG/ML FLAKON, 1 ADET ... TERRAFUNGIN 100 MG/2 ML AMPUL, 1 ADET ... TERRAFUNGIN 250 MG/2 ML AMPUL, 1 ADET …
Misoprostol
Misoprostol is a prostaglandin analog used to reduce the risk of NSAID related ulcers, manage miscarriages, prevent post partum hemorrhage, and also for first trimester abortions.[L7616,L7619,A181589,A181583,A181697] The stimulation of prostaglandin receptors in the stomach reduces gastric acid secretion, while stimulating these receptors in the uterus and cervix can increase the...
Approved
Matched Iupac: … methyl 7-[(1R,2R,3R)-3-hydroxy-2-[(1E)-4-hydroxy-4-methyloct-1-en-1-yl]-5-oxocyclopentyl]heptanoate …
Matched Mixtures name: … Diclofenac Sodium/Misoprostol DICLOFENAC-SODIUM-MISOPROSTOL ... Diclofenac Sodium/Misoprostol DICLOFENAC-SODIUM-MISOPROSTOL ... Diclofenac Sodium/Misoprostol diclofenac-sodium-misoprostol …
Matched Products: … MISODEL 200 MCG VAJINAL SALIM SISTEMI ,1 ADET ... MISODEL 200 MCG VAJINAL SALIM SISTEMI ,5 ADET …
Matched Mixtures name: … Diclofenac Sodium/Misoprostol DICLOFENAC-SODIUM-MISOPROSTOL ... Diclofenac Sodium/Misoprostol DICLOFENAC-SODIUM-MISOPROSTOL ... Diclofenac Sodium/Misoprostol diclofenac-sodium-misoprostol …
Matched Products: … MISODEL 200 MCG VAJINAL SALIM SISTEMI ,1 ADET ... MISODEL 200 MCG VAJINAL SALIM SISTEMI ,5 ADET …
Bepridil
A long-acting, non selective, calcium channel blocker with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist. It is no longer marketed in the United States, as it has been implicated in causing...
Approved
Withdrawn
Matched Iupac: … N-benzyl-N-[3-(2-methylpropoxy)-2-(pyrrolidin-1-yl)propyl]aniline …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Benzoic acid
A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid. As the sodium salt form, sodium benzoate is used as a treatment for urea cycle disorders due to its ability to bind amino acids. This leads...
Approved
Investigational
Matched Description: … Recent research shows that sodium benzoate may be beneficial as an add-on therapy (1 gram/day) in schizophrenia ... As the sodium salt form, sodium benzoate is used as a treatment for urea cycle disorders due to its ability …
Matched Salts cas: … 532-32-1 …
Matched Mixtures name: … Sodium Phenylacetate and Sodium Benzoate ... Sodium Phenylacetate and Sodium Benzoate ... Sodium Phenylacetate and Sodium Benzoate …
Matched Salts name: … Sodium benzoate …
Matched Categories: … sodium benzoate and sodium phenylacetate ... sodium benzoate ... caffeine and sodium benzoate …
Matched Salts cas: … 532-32-1 …
Matched Mixtures name: … Sodium Phenylacetate and Sodium Benzoate ... Sodium Phenylacetate and Sodium Benzoate ... Sodium Phenylacetate and Sodium Benzoate …
Matched Salts name: … Sodium benzoate …
Matched Categories: … sodium benzoate and sodium phenylacetate ... sodium benzoate ... caffeine and sodium benzoate …
Crotamiton
Crotamiton is a scabicidal and antipruritic agent available as a cream or lotion for topical use only. It is a colorless to slightly yellowish oil, having a faint amine-like odor. It is miscible with alcohol and with methanol.
Approved
Matched Products: … DERMITON % 10 LOSYON, 1 ŞIŞE …
Displaying drugs 76 - 100 of 8459 in total