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Displaying drugs 76 - 100 of 8504 in total

Ajmaline

An alkaloid found in the root of Rauwolfia serpentina, among other plant sources. It is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac action potentials. Ajmaline produces potent sodium channel blocking effects and a very short half-life which makes it a very...
Approved
Experimental
Matched Synonyms: … (5aR,6S,8S,10S,11S,11aS,12aR,13R)-5-methyl-5a,6,8,9,10,11,11a,12-octahydro-5H-6,10:11,12a-dimethanoindolo …
Matched Description: … Ajmaline produces potent sodium channel blocking effects and a very short half-life which makes it a …
Matched Categories: … Antiarrhythmics, Class I ... Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers …
Matched Products: … Gilurytmal 5 mg/ml Injektionslösung und Konzentrat zur Herstellung einer Infusionslösung …

Risedronic acid

Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Investigational
Matched Iupac: … [1-hydroxy-1-phosphono-2-(pyridin-3-yl)ethyl]phosphonic acid …
Matched Salts cas: … 115436-72-1 …
Matched Mixtures name: … Risedronate Sodium ... Risedronate Sodium ... Risedronate Sodium …
Matched Salts name: … Risedronate sodium ... Risedronate sodium monohydrate ... Risedronate sodium hemi-pentahydrate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Risedronate Sodium ... Risedronate Sodium Amorphous Fv2910cl ... ACTONEL TABLET 5 mg …

Sulfadiazine

One of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.
Approved
Investigational
Vet approved
Matched Synonyms: … N(1)-2-Pyrimidylsulfanilamide ... N(1)-2-Pyrimidinylsulfanilamide …
Matched Iupac: … 4-amino-N-(pyrimidin-2-yl)benzene-1-sulfonamide …
Matched Salts name: … Sulfadiazine sodium …
Matched Products: … Sulfadiazine Sodium …

Moricizine

An antiarrhythmia agent used primarily for ventricular rhythm disturbances.
Approved
Investigational
Withdrawn
Matched Salts cas: … 29560-58-5 …
Matched Categories: … Antiarrhythmics, Class I ... Heterocyclic Compounds, 1-Ring ... Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers …

Omeprazole

Originally approved by the FDA in 1989, omeprazole is a proton-pump inhibitor, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid. This drug was the first clinical useful drug in its class,...
Approved
Investigational
Vet approved
Matched Salts cas: … 95382-33-5 …
Matched Mixtures name: … Omeprazole/sodium Bicarbonate ... Omeprazole/sodium Bicarbonate ... Omeprazole Sodium Bicarbonate …
Matched Salts name: … Omeprazole sodium …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … PRAZIDEC - I ... OMEPRAZOLE SODIUM ... OMEPRAZOLE SODIUM MONOHYDRATE …

Tositumomab

Murine IgG2a lambda monoclonal antibody against CD20 antigen (2 heavy chains of 451 residues, 2 lambda chains of 220 residues). It is produced in an antibiotic-free culture of mammalian cells. It can be covalently linked to Iodine 131 (a radioactive isotope of iodine).
Approved
Investigational
Matched Salts name: … Tositumomab I-131 …

Vasopressin

Vasopressin (arginine-vasopressin or antidiuretic hormone) is a nonapeptide primarily produced in the hypothalamus that exhibits diverse physiological functions related to diuresis, hemodynamic modulation, and behaviour.[A110, A111, A112, A113, A228008] Vasopressin is very similar to oxytocin, differing in the third and eighth amino acids. Despite a wide variety of functions, exogenous...
Approved
Matched Iupac: … -dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl]pyrrolidin-2-yl}formamido)-N-(carbamoylmethyl)-5- ... 2-({1-[19-amino-13-benzyl-10-(2-carbamoylethyl)-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18 ... [(diaminomethylidene)amino]pentanamide; 6-amino-2-({1-[19-amino-13-benzyl-10-(2-carbamoylethyl)-7-(carbamoylmethyl …
Matched Description: … during systemic shock by increasing vasoconstriction and renal fluid reuptake by acting through V1< …
Matched Salts cas: … 113-79-1 …
Matched Products: … Vasopressin in 0.9% Sodium Chloride …

Ceftizoxime

A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe...
Approved
Withdrawn
Matched Synonyms: … 7-[2-(2-Amino-thiazol-4-yl)-2-methoxyimino-acetylamino]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2- …
Matched Iupac: … (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0 …
Matched Salts cas: … 68401-82-1 …
Matched Salts name: … Ceftizoxime sodium …
Matched Products: … CEFTIZOXIME SODIUM ... CEFIZOX 1 GR FLAKON, 1 ADET ... CEFİZOX 1 G IM ENJEKSİYONLUK ÇÖZELTİ TOZU İÇEREN FLAKON, 1 ADET …

Dextrose, unspecified form

Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through...
Approved
Vet approved
Matched Mixtures name: … DEXTROSE AND SODIUM CHLORIDE INJECTION U.S.P.D-5-1/4S ... DEXTROSE AND SODIUM CHORIDE INJECTION U.S.P. D-5-1/2S ... DEXTROSE AND SODIUM CHORIDE INJECTION U.S.P. D-5-1/3 S …
Matched Products: … Dextrose Inj 5% ... GLUCOSIO 5% BAXTER ... 5% Dextrose Injection USP …

Pilocarpine

A naturally occurring alkaloid derived from the Pilocarpus plants, pilocarpine is a muscarinic acetylcholine agonist.[A262016, A262036] Pilocarpine is associated with parasympathomimetic effects by selectively working on muscarinic receptors. Pilocarpine is used to treat dry mouth and various ophthalmic conditions, including elevated intraocular pressure and glaucoma. The usage of glaucoma by...
Approved
Investigational
Matched Synonyms: … 2(3H)-FURANONE, 3-ETHYLDIHYDRO-4-((1-METHYL-1H-IMIDAZOL-5-YL)METHYL)-, (3S-CIS)- …
Matched Iupac: … (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]oxolan-2-one …
Matched Salts cas: … 148-72-1 …
Matched Mixtures name: … E-pilo-1 Oph Soln ... E-pilo 1 Ophthalmic Solution …
Matched Products: … -carpine 1% ... PILOMANN 1% ... Pilocarpine 1% …

Fusidic acid

An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed) It acts by inhibiting translocation during protein synthesis. It is often used topically in creams and eyedrops but is available in systemic formulations including tablets and injections.
Approved
Investigational
Matched Iupac: … ylidene]-6-methylhept-5-enoic acid ... 11aR)-2-(acetyloxy)-7,10-dihydroxy-3a,3b,6,9a-tetramethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1- …
Matched Salts cas: … 172343-30-5 …
Matched Mixtures name: … FUCIDIN H %2 + %1 KREM, 30 G ... Fusicutan 20 mg/g + 1 mg/g Creme ... Fucibet Lipid 20 mg/g + 1 mg/g Creme …
Matched Salts name: … Fucidate sodium …
Matched Products: … STAFINE %1 VISKOZ GOZ DAMLASI, 5 G ... FUCİTHALMİC %1 VİSKOZ GÖZ DAMLASI, SÜSPANSİYON, 5 G ... FUCIDIN INTERTULLE, 5 ADET …

Golimumab

Golimumab is a human IgG1қ monoclonal antibody derived from immunizing genetically engineered mice with human TNFα. Golimumab binds and inhibits soluble and transmembrane human TNFα. Increased TNFα is associated with chronic inflammation. Thus golimumab is indicated for use in adults (i) as an adjunct to methotrexate treatment in patients with...
Approved
Matched Description: … Thus golimumab is indicated for use in adults (i) as an adjunct to methotrexate treatment in patients …
Matched Products: … SIMPONI 50MG ILO I E FER ... Concentrate for Solution for Infusion 12.5mg/1 ml ... SIMPONI 50 MG ENJEKSİYONLUK COZELTİ ICEREN KULLANIMA HAZIR ENJEKTOR, 1 ADET …

Aliskiren

Aliskiren is the first drug in the renin inhibitor drug class and is used for the treatment of hypertension. It was developed by Speedel and Novartis and initially approved by the FDA in early 2007. Aliskiren has been proven to efficacious in reducing blood pressure when used alone or in...
Approved
Investigational
Matched Iupac: … (2S,4S,5S,7S)-5-amino-N-(2-carbamoyl-2,2-dimethylethyl)-4-hydroxy-7-{[4-methoxy-3-(3-methoxypropoxy)phenyl …

Montelukast

Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs.[L6301,L6304,L6307,L6310,L6325,L6328,L6331] Although capable of demonstrating effectiveness, the use of such LTRAs like montelukast is typically in addition to or...
Approved
Matched Synonyms: … 1-[[[(1 R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl] phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl] ... (R-(E))-1-(((1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl …
Matched Iupac: … 2-[1-({[(1R)-1-{3-[(1E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl …
Matched Salts cas: … 151767-02-1 …
Matched Mixtures name: … BROCRIPTIN® 10 MG/ 5 MG ... DESMONT 5/10 MG 90 FILM KAPLI TABLET ... BRONCHOREST 10 MG/5 MG KAPSÜL ,30 KAPSÜL …
Matched Salts name: … Montelukast sodium …
Matched Products: … Spirant 5 Chewable (Montelukast sodium tablets 5 mg) ... Montelukast Sodium ... Montelukast sodium …

Idoxuridine

An analog of deoxyuridine that inhibits viral DNA synthesis. The drug is used as an antiviral agent.
Approved
Investigational
Matched Synonyms: … 1-beta-D-2'-Deoxyribofuranosyl-5-iodouracil ... 1-(2-Deoxy-beta-D-ribofuranosyl)-5-iodouracil ... 5-Iododeoxyuridine …
Matched Iupac: … 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Icosapent

Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conversion into the thromboxane-2 and prostaglandin-2 families.
Approved
Nutraceutical
Matched Mixtures name: … ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL (1 ML VE 2 ML) X 6 AMPUL ... ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL (1 ML VE 2 ML) X 25 AMPUL …
Matched Salts name: … Icosapent sodium …
Matched Products: … FOLSET 5 MG TABLET ... FOLSET 5 MG TABLET, 50 ADET ... FOLAS 5 MG TABLET, 50 ADET …

Octasulfur

Sulfur is a chemical element that is present in all living tissues. The most commonly used form of pharmaceutical sulfur is Octasulfur (S8). After calcium and phosphorus, it is the third most abundant mineral in the human body. Sulfur is also found in garlic, onions and broccoli. People take sulfur...
Approved
Matched Mixtures name: … Sodium Polysulthionate, 5-mthf ... Sodium Sulfacetamide 10 Sulfur 5 ... Sodium Sulfacetamide 10 and Sulfur 5 …
Matched Products: … Sodium Sulfacetamide and Sulfur ... Sul-ray Acne Treatment Sop 5% ... Rodan and Fields Unblemish 1 Wash Acne Medicated Cleanser …

Nicotinamide

An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
Approved
Investigational
Matched Mixtures name: … Hyaluronic Acid Sodium Salt 1% / Niacinamide 4% / Tacrolimus 0.1% ... Multi Plex I - Tab ... Ascorbyl Palmitate 2% / Hyaluronic Acid Sodium Salt 0.2% / Niacinamide 5% / Tretinoin 0.025% …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Costem cell 5 N ... Karatica I M Cure …

Desmopressin

Desmopressin (dDAVP), a synthetic analogue of 8-arginine vasopressin (ADH), is an antidiuretic peptide drug modified by deamination of 1-cysteine and substitution of 8-L-arginine by 8-D-arginine. ADH is an endogenous pituitary hormone that has a crucial role in the control of the water content in the body. Upon release from the...
Approved
Matched Synonyms: … 1-deamino-8-D-arginine vasopressin ... 1-desamino-8-D-arginine vasopressin ... 1-(3-mercaptopropionic acid)-8-D-arginine-vasopressin …
Matched Iupac: … (2R)-2-{[(2S)-1-[(4R,7S,10S,13S,16S)-13-benzyl-10-(2-carbamoylethyl)-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl ... 6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl]pyrrolidin-2-yl]formamido}-5- …
Matched Description: … analogue of 8-arginine vasopressin (ADH), is an antidiuretic peptide drug modified by deamination of 1- …
Matched Products: … Octostim 1,5 mg/ml - Nasalspray ... EMOSINT 20 MCG / 1 ML SOLUCION INYECTABLE ... OCTOSTIM 30 MCG/2 ML IV/SC ENJEKSIYON IÇIN ÇÖZELTI IÇEREN AMPUL, 1 ADET …

Idebenone

Idebenone is a synthetic analogue of ubiquinone (also known as Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC). It has been proposed that by interacting with the ETC, idebenone increases ATP production required for mitochondrial function, reduces free radicals, inhibits lipid peroxidation, and...
Approved
Investigational
Matched Synonyms: … 6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-p-benzoquinone ... 6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone ... 2,3-dimethoxy-5-methyl-6-(10'-hydroxydecyl)-1,4-benzoquinone …
Matched Description: … transfer electrons directly to complex III of the mitochondrial ETC, thereby circumventing complex I …
Matched Mixtures name: … EVERON 90/5 MG FILM KAPLI TABLET ,50 TABLET ... EVERON 90/5 MG FILM KAPLI TABLET ,100 TABLET ... BERMAXIN 90/10/5 MG FILM TABLET ,FILM TABLET, 28 ADET …

Picosulfuric acid

Picosulfuric acid is found in laxative products. Sodium picosulfate is a used to treat constipation or induce colon cleansing to prepare the large bowels before colonoscopy or surgery. The combination product containing sodium picosulfate and magnesium citrate was introduced to the Canadian market in 2005 and has been used in...
Approved
Matched Description: … Sodium picosulfate is a used to treat constipation or induce colon cleansing to prepare the large bowels ... The combination product containing sodium picosulfate and magnesium citrate was introduced to the Canadian …
Matched Mixtures name: … Sodium Picosulfate, Magnesium Oxide and Anhydrous Citric Acid …
Matched Salts name: … Sodium picosulfate monohydrate ... Sodium picosulphate anhydrous …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... sodium picosulfate ... sodium picosulfate, combinations …

Formaldehyde

A highly reactive aldehyde gas formed by oxidation or incomplete combustion of hydrocarbons. In solution, it has a wide range of uses: in the manufacture of resins and textiles, as a disinfectant, and as a laboratory fixative or preservative. Formaldehyde solution (formalin) is considered a hazardous compound, and its vapor...
Approved
Vet approved

Vancomycin

Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear. As of January 29 2018, CutisPharma's Firvanq is the only FDA approved vancomycin oral liquid treatment option available for the the treatment of...
Approved
Matched Iupac: … (1S,2R,18R,19R,22S,25R,28R,40S)-48-{[(2S,3R,4S,5S,6R)-3-{[(2S,4S,5S,6S)-4-amino-5-hydroxy-4,6-dimethyloxan ... pentanamido]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2^{3,6}.2^{14,17}.1^ ... {8,12}.1^{29,33}.0^{10,25}.0^{34,39}]pentaconta-3,5,8,10,12(48),14,16,29(45),30,32,34,36,38,46,49-pentadecaene …
Matched Products: … Vancomycin Injection USP In 0.9% Sodium Chloride ... EDICIN 1 G IV INFÜZYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 5 ADET ... Vancomycin Injection USP In 5% Dextrose …

Irinotecan

Irinotecan is a topoisomerase inhibitor used for chemotherapy. It is a water-soluble analogue of camptothecin, which is extracted from the Chinese tree Camptotheca acuminate. The bis-piperidine side chain in the structure of irinotecan bestows enhanced water solubility. As an anticancer drug, irinotecan was first commercially available in Japan in 1994...
Approved
Investigational
Matched Synonyms: … (3-(2,4-dihydroxy-5-isopropylphenyl)-5-hydroxy-4H-1,2,4-triazol-4-yl)-1H-indol-1-yl)ethyl)piperidine- ... 1-carboxylate ... -4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl 4-(2-(5- …
Matched Iupac: … 21),2,4(9),5,7,10,15(20)-heptaen-7-yl [1,4'-bipiperidine]-1'-carboxylate ... diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1( …
Matched Description: … [L50186] The active metabolite SN-38 is also a potent inhibitor of DNA topoisomerase I. ... Both irinotecan and SN-38 mediate antitumor activity by forming a complex with topoisomerase I and blocking …
Matched Categories: … Topoisomerase I Inhibitors ... Topoisomerase 1 (TOP1) inhibitors …
Matched Products: … TEKAMEN 100 MG/5 ML IV INFUZYON COZ.ICEREN 1 FLAKON ... IROTEN 100 MG/5 ML IV INFUZYONLUK KONSANTRE COZELTI, 1 ADET ... IRONTU 100 MG/5 ML IV INFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET …

Gemifloxacin

Gemifloxacin is a quinolone antibacterial agent with a broad-spectrum activity that is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. It is available in oral formulations. Gemifloxacin acts by inhibiting DNA synthesis through the inhibition of both DNA gyrase and topoisomerase IV, which are...
Approved
Investigational
Matched Iupac: … 7-[(4Z)-3-(aminomethyl)-4-(methoxyimino)pyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8 …
Matched Products: … ONFACT 320 MG FİLM TABLET, 5 ADET ... FACTIVE 320 MG FİLM TABLET, 5 ADET ... GEMİLOKS 320 MG FİLM KAPLI TABLET, 5 ADET …
Displaying drugs 76 - 100 of 8504 in total