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Displaying drugs 1026 - 1050 of 1332 in total

Trabectedin

Trabectedin, also referred as ET-743 during its development, is a marine-derived antitumor agent discovered in the Carribean tunicate Ecteinascidia turbinata and now produced synthetically. Trabectedin has a unique mechanism of action. It binds to the minor groove of DNA interfering with cell division and genetic transcription processes and DNA repair...
Approved
Investigational
Matched Description: … It is approved for use in Europe, Russia and South Korea for the treatment of advanced soft tissue sarcoma ... and ovarian cancer. ... and DNA repair machinery. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … YONDELIS 1MG FOR INJECTION ... YONDELIS Powder for Injection 1mg/vial …

Bicisate

Bicisate, also known as ethyl cysteinate dimer (ECD), is a N,N'-1,2-ethylene-di-yl-bis-L-cysteinate diethyl ester. It is used in conjunction with technetium Tc99m as a tracer to measure cerebral blood flow with single-photon emission computed tomography (SPECT). The complex of bicisate and technetium Tc99m as a kit was developed by Lantheus Medcl...
Approved
Investigational
Matched Description: … [A32374] The complex of bicisate and technetium Tc99m as a kit was developed by Lantheus Medcl and FDA-approved …
Matched Products: … NEUROLITE KIT FOR THE PREPARATION OF Tc99m BICISATE FOR INJECTION …

Romosozumab

Romosozumab is a humanized monoclonal antibody indicated for the treatment of osteoperosis in postmenopausal women at high risk of fracture and patients who have failed in other treatments or are intolerant to other osteoperosis therapies . Romosozumab prevents bone resorption and induces the formation of bone though it is associated...
Approved
Investigational
Matched Description: … In a comparison study of post menopausal women with osteoporosis and a past fracture, romosozumab for ... 12 months followed by alendronic acid for 12 months was superior to alendronic acid alone for 24 months ... increased risk of cardiac death, heart attack, and stroke in one study[L5921,L5924]. …
Matched Categories: … Drugs for Treatment of Bone Diseases ... Amino Acids, Peptides, and Proteins ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105 MG/1.17 ML ... EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105MG/1.17ML …

Rasburicase

Rasburicase is a recombinant urate-oxidase enzyme produced by a genetically modified Saccharomyces cerevisiae strain. The cDNA coding for rasburicase was cloned from a strain of Aspergillus flavus.
Approved
Investigational
Matched Description: … The cDNA coding for rasburicase was cloned from a strain of _Aspergillus flavus_. …
Matched Categories: … Enzymes and Coenzymes ... Detoxifying Agents for Antineoplastic Treatment …
Matched Products: … FASTURTEC POWDER FOR SOLUTION FOR INFUSION 1.5 mg/vial …

Gadoxetic acid

Gadoxetic acid (gadoxetate) is a paramagnetic gadolinium-containing ionic linear contrast agent in which its salt form, gadoxetate disodium, is used for intravenous injection. Ethoxybenzyl diethylenetriaminepentaacetic acid is the moiety that chelates with a gadolinium ion and forms a stable complex with it to make up the drug. Gadoxetate is a...
Approved
Matched Description: … hepatobiliary phase and thus has different pharmacokinetic and pharmacodynamic properties compared to ... forms a stable complex with it to make up the drug. ... , gadoxetate disodium, is used for intravenous injection. …
Matched Products: … Primovist 0.25 mmol/ml Solution for injection ... PRIMOVIST 0.25 MMOL/ML, SOLUTION FOR INJECTION …

Sincalide

Sincalide is a medication given by injection to assist in the diagnosis of gallbladder and pancreas disorders. It is identified as the 8-amino acid C-terminal segment of cholecystokinin and is also known as CCK-8. Naturally occurring cholecystokinin is a gastrointestinal peptide hormone normally essential for stimulating protein and fat digestion...
Approved
Matched Description: … small bowel for cholesterol analysis, enzymatic activity analysis, and x-ray examination respectively ... protein and fat digestion in the body. ... Naturally occurring cholecystokinin is a gastrointestinal peptide hormone normally essential for stimulating …
Matched Categories: … Tests for Bile Duct Patency ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Sincalide for Injection …

Edaravone

Edaravone is a free radical scavenger and neuroprotective agent with antioxidant properties. It has three tautomers. Edaravone works to scavenge reactive oxygen species, which have been implicated in neurological disorders, such as amyotrophic lateral sclerosis (ALS) and cerebral ischemia.[A19140,L44007,A254257] The intravenous formulation of edaravone was first approved in Japan in...
Approved
Investigational
Matched Description: … Medicinal Products for Human Use (CHMP) for a long-term study demonstrating the long-term efficacy and ... [L44007] It was later approved for the treatment of amyotrophic lateral sclerosis (ALS) in Japan and ... Edaravone is a free radical scavenger and neuroprotective agent with antioxidant properties. …
Matched Products: … RADICAVA™ IV Concentrate Solution for Infusion 30mg/20mL …

Human cytomegalovirus immune globulin

Cytomegalovirus immunoglobulin is obtained from pooled adult human plasma selected for high titers of antibody for cytomegalovirus (CMV). It contains purified immunoglobulin G (IgG) antibodies targeting cytomegalovirus (CMV)[FDA label]. Cytomegalovirus, a member of the herpes virus family, is ubiquitous the human population, leading to infections which are followed by life-long...
Approved
Matched Description: … antibody for cytomegalovirus (CMV). ... Cytomegalovirus immunoglobulin is obtained from pooled adult human plasma selected for high titers of ... CMV infection can lead to a high fever and severe organ-specific damage with significant morbidity and …
Matched Categories: … Antiinfectives for Systemic Use ... Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Matched Products: … MEGALOTECT CP SOLUTION FOR INFUSION 100 U/ML …

Pyrophosphoric acid

Approved
Experimental
Matched Mixtures name: … Phosphotec …
Matched Categories: … Phosphate salts …
Matched Products: … TECHNESCAN PYP, KIT FOR RADIOPHARMACEUTICAL PREPARATION, 20MG/VIAL …

Dupilumab

Dupilumab is a fully human monoclonal antibody of the immunoglobulin G4 subclass that binds to the interleukin-4 (IL-4) receptor, inhibiting the receptor signaling pathways. As an interleukin-4 receptor alpha antagonist, dupilumab inhibits the signaling of pro-inflammatory cytokines, called interleukins (IL), that induce inflammatory and immunological reactions in several atopic or...
Approved
Investigational
Matched Description: … immunological reactions in several atopic or allergic conditions, such as eczema, allergic reaction, and ... inhibits the signaling of pro-inflammatory cytokines, called interleukins (IL), that induce inflammatory and ... dermatitis, asthma as an add-on maintenance treatment, chronic rhinosinusitis with nasal polyposis, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Agents for Dermatitis, Excluding Corticosteroids ... Skin and Mucous Membrane Agents …
Matched Products: … Dupixent 300 mg Solution for Injection in Pre-filled Syringe ... Dupixent 200mg Solution for Injection in Pre-Filled Syringe ... DUPIXENT SOLUTION FOR INJECTION IN A PRE-FILLED SYRINGE 300 mg/2ml …

Fomepizole

Fomepizole is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. Fomepizole is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites.
Approved
Vet approved
Matched Description: … alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and …
Matched Products: … Fomepizole for Injection …

Methylnaltrexone

Methylnaltrexone is a pheriphally-acting μ-opioid antagonist that acts on the gastrointestinal tract to decrease opioid-induced constipation without producing analgesic effects or withdrawal symptoms. It is also a weak CYP2D6 inhibitor. FDA approved in 2008.
Approved
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Constipation …
Matched Products: … Relistor Solution For Injection 12mg/0.6mL …

Coffee bean

Coffee bean allergenic extract is used in allergenic testing.
Approved
Matched Products: … Coffee for Diagnostic Use Only …

Anthrax vaccine

Anthrax vaccine is a vaccine used for the pre- or post-exposure prophylaxis of disease in those at high risk of, suspected or confirmed exposure to Bacillus anthracis. It is subcutaneously or intramuscularly administered. It is derived from cell-free filtrates of microaerophilic cultures of an avirulent, nonencapsulated strain of Bacillus anthracis...
Approved
Matched Description: … [L47561] There are currently 2 anthrax vaccines approved by the FDA: BioThrax in August 15, 2016 and ... Anthrax vaccine is a vaccine used for the pre- or post-exposure prophylaxis of disease in those at high ... an Anthrax terrorist attack or for pre-exposure prophylaxis of personnel going to specific arenas around …
Matched Products: … BioThrax (Anthrax Vaccine Adsorbed) Supension for Injection 50?g/dose (nominal) …

Spectinomycin

An antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.
Approved
Investigational
Vet approved
Matched Description: … It is active against gram-negative bacteria and used for the treatment of gonorrhea. …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … TROBICIN FOR INJECTION 2 g/vial …

Obexelimab

Obexelimab is under investigation in clinical trial NCT02725515 (A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus).
Investigational
Matched Synonyms: … XMAB5871 (HUMANIZED ANTI-CD19 ANTIBODY WITH AN FC PORTION ENGINEERED FOR INCREASED AFFINITY (200- TO …

Chlorzoxazone

A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
Approved
Matched International brands: … Strifon Forte DSC …
Matched Description: … is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and …
Matched Mixtures name: … Extra Strength Tylenol Aches and Strains ... Parafon Forte ... Acetazone Forte …
Matched Categories: … Benzoxazoles and derivatives ... Oxazol, Thiazine, and Triazine Derivatives …
Matched Products: … Parafon Forte ... Parafon Forte DSC ... PARAFLEX FORTE TABLET 500 MG, 20 ADET …

Amphotericin B

Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While...
Approved
Investigational
Matched Description: … The antibiotic is without effect on bacteria, rickettsiae, and viruses. ... Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B. ... Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and …
Matched Categories: … Antiinfectives and Antiseptics for Local Oral Treatment ... Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Antimycotics for Systemic Use …
Matched Products: … AMPHOTRET FOR INJECTION USP 50MG ... Amphotericin B for Injection, USP ... AMBISOME FOR INJECTION 50 mg/vial …

Fremanezumab

Fremanezumab is a humanized monoclonal antibody targeted against human calcitonin gene-related peptide (CGRP) for the prevention of migraine headaches. It was developed by Teva Pharmaceuticals USA and approved by the FDA in September 2018. Along with other recently approved anti-CGRP therapies such as galcanezumab, erenumab, and the oral CGRP antagonist...
Approved
Investigational
Matched Description: … Fremanezumab is a humanized monoclonal antibody targeted against human calcitonin gene-related peptide (CGRP) for ... [L11749] It was developed by Teva Pharmaceuticals USA and approved by the FDA in September 2018. ... [L11779] Along with other recently approved anti-CGRP therapies such as [galcanezumab], [erenumab], and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … AJOVY SOLUTION FOR INJECTION IN PRE-FILLED PEN 225 MG/1.5ML ... AJOVY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 225 MG/1.5ML …

Arsenic trioxide

Arsenic trioxide is a chemotherapeutic agent of idiopathic function used to treat leukemia that is unresponsive to first line agents. It is suspected that arsenic trisulfide induces cancer cells to undergo apoptosis. In general, arsenic is known to be a naturally toxic substance capable of eliciting a variety of dangerous...
Approved
Investigational
Matched Description: … The enzyme thioredoxin reductase has recently been identified as a target for arsenic trioxide. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Arsenic Trioxide for Injection ... Teva-arsenic Trioxide for Injection ... Arsenic Trioxide Solution for Injection …

Clostridium botulinum

Experimental
Matched Products: … DYSPORT FOR INJECTION 300u/vial ... DYSPORT FOR INJECTION 500 u/vial ... NEURONOX LYOPHILIZED POWDER FOR INJECTION 100 UNITS/VIAL …

Technetium Tc-99m sestamibi

Technetium Tc-99m sestamibi (commonly sestamibi) is a pharmaceutical agent used in nuclear medicine imaging. The drug is a coordination complex consisting of the radioisotope technetium-99m bound to six methoxyisobutylisonitrile (MIBI) ligands, hence the name sesta (6) MIBI.. Following intravenous injection of the drug, Technetium Tc-99m sestamibi is taken up by...
Approved
Investigational
Matched Description: … for: 1) detecting coronary artery disease by localizing myocardial ischemia (reversible defects) and ... infarction (non-reversible defects); and 2) evaluating myocardial function and developing information ... for use in patient management decisions. …
Matched Categories: … Indicators and Reagents …
Matched Products: … Kit for the Preparation of Technetium Tc99m Sestamibi …

Nefopam

Nefopam is under investigation for the prevention of Cholecystitis and Post Anaesthetic Shivering. Nefopam has been investigated for the prevention of Kidney Transplantation.
Approved
Investigational
Matched Description: … Nefopam is under investigation for the prevention of Cholecystitis and Post Anaesthetic Shivering. ... Nefopam has been investigated for the prevention of Kidney Transplantation. …
Matched Products: … ACUPAN SOLUTION FOR INJECTION 20MG/2ML …

Japanese encephalitis virus strain sa 14-14-2 antigen (formaldehyde inactivated)

Approved
Matched Products: … IXIARO Suspension for Injection 0.5ml in pre-filled syringe …

Vigabatrin

Vigabatrin is an analog of gamma-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the central nervous system, used in the treatment of refractory seizures and infantile spasms. It irreversibly inhibits the enzyme responsible for GABA metabolism, thereby increasing levels of circulating GABA. Although administered as a racemic mixture, only the...
Approved
Matched Description: … [A202124] Its use is now generally reserved for patients who have failed alternative therapies, and its ... inhibitory neurotransmitter in the central nervous system, used in the treatment of refractory seizures and ... [A202037] It was first introduced as an antiepileptic agent in the United Kingdom in 1989 and was …
Matched Products: … Vigabatrin for Oral Solution ... Vigabatrin for oral solution USP, 500 mg …
Displaying drugs 1026 - 1050 of 1332 in total