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Displaying drugs 126 - 150 of 5596 in total
Atezolizumab is a humanized monoclonal antibody used to prevent the interaction of PD-L1 and PD-1, removing inhibition of immune responses seen in some cancers.[A18493,L7489] This medication is reserved for patients whose tumors express PD-L1, cannot receive platinum-based chemotherapy, or whose tumors do not respond to platinum-based chemotherapy. Atezolizumab was granted...
Approved
Investigational
Matched Products: … TECENTRIQ CONCENTRATE FOR SOLUTION FOR INFUSION 1200 MG/ 20 ML ... TECENTRIQ 1200 MG / 20 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET …
Vardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and an oral therapy for the treatment of erectile dysfunction.[L45563,L45568] During sexual stimulation, nitric oxide (NO) is released from nerve endings and endothelial cells in the corpus cavernosum, activating the enzyme guanylate cyclase and increasing the...
Approved
Matched Products: … เลวิตรา 20 ... LEVITRA TABLET 20 mg ... VARDENARISTO 20 mg Filmtabletten …
Citalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs.[A261316,A14720] Citalopram enhances serotonergic transmission through the...
Approved
Matched Products: … Celexa 20 mg ... Citalopram-20 ... CITALOPRAM-NEURAX 20 MG …
Mobocertinib is a kinase inhibitor targeted against human epidermal growth factor receptor (EGFR). It is used specifically in the treatment of non-small cell lung cancer (NSCLC) caused by exon 20 insertion mutations in the EGFR gene, which are typically associated with a poorer prognosis (as compared to "classical" EGFR mutants...
Approved
Investigational
Matched Description: … It is used specifically in the treatment of non-small cell lung cancer (NSCLC) caused by exon 20 insertion ... of treating this otherwise treatment-resistant NSCLC, exerting an inhibitory effect on _EGFR_ exon 20 ... September 2021 for the treatment of locally advanced or metastatic NSCLC in patients with _EGFR_ exon 20
Tioconazole is an imidazole antifungal used to treat fungal and yeast infections. Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus". Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. In...
Approved
Matched Products: … TIOCAN %1 20 GR KREM ... TIODERMA %1 20 GR PUDRA ... TİOCURE %1 KREM, 20 GRAM …
Clobazam belongs to the 1,5-benzodiazepine class of drugs and is marketed under different names, Onfi, Frisium, Urbanyl, and others. . Clobazam was first synthesized in 1966 and first published in 1969, following the incidental synthesis and discovery of the first benzodiazepine chlordiazepoxide in the 1950s. Unlike older 1,4-benzodiazepines, clobazam has...
Approved
Illicit
Matched Products: … URBADAN® 20 MG ... FRISIUM 20 TABS ... OBAX 20 MG TABLETAS …
Tafamidis and tafamidis meglumine (FX-1006A) are benzoxazole derivatives developed by FoldRX. Tafamidis is structurally similar to diflusinal. Tafamidis was granted an EMA market authorisation on 16 November 2011 and FDA approval on 3 May 2019.
Approved
Investigational
Matched Iupac: … 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid …
Matched Products: … VYNDAQEL® 20 MG CAPSULABLANDA. …
Rupatadine is a dual histamine H1 receptor and platelet activating factor receptor antagonist that is used for symptomatic relief in seasonal and perennial rhinitis as well as chronic spontaneous urticaria. It was approved for marketing in Canada under the tradename Rupall and comes in tablet formulation for adult use and...
Approved
Matched Salts cas: … 156611-76-6
Matched Products: … RUFTAN 10 MG TABLET, 20 ADET ... ANTHIX 10MG TABLET ,20 ADET ... RUPAX 10 MG TABLET, 20 ADET …
Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. It is available as a tablet and is usually dosed twice daily. Another leukotriene receptor antagonist is montelukast (Singulair), which is usually taken just once...
Approved
Investigational
Matched Products: … Accolate Tab 20 mg ... CARROX 20 MG FILM TABLET, 28 TABLET ... ACCOLATE 20 MG TABLETA RECUBIERTA. …
Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine.[A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972.[A175390,A190276] Since nifedipine's development, second and third generation dihydropyridines have been developed with slower onsets and longer...
Approved
Matched Products: … NIFEDIPIN T 20 STADA RETARD TABLET 20 mg ... ADALAT CR 20 ... Adalat Pa 20
Pentoxifylline (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and also has both anti-oxidant and anti-inflammatory properties.[A226415, L30300] Although originally developed to treat intermittent claudication, a form of exertion-induced leg pain common in patients with peripheral arterial disease, PTX has been investigated for its possible...
Approved
Investigational
Matched Products: … PENTOX SR 400 MG KAPSUL, 20 ADET ... HEMOPENE RETARD 600 MGTABLET, 20 ADET ... İSKEMOKS 400 MG SR MİKROPELLET KAPSÜL, 20 KAPSÜL …
Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration . It was initially approved by the FDA in 1991 . It is primarily used for the treatment of respiratory, enteric and genitourinary infections and may be used instead of other macrolides for...
Approved
Matched Iupac: … (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl ... 13-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,6,8,10,12,14-heptamethyl-1-oxa-6- …
Matched Description: … The results were positive, all patients taking the combination were virologically cured within 6 days …
Matched Products: … TREMAC 250 MG KAPSÜL, 6 KAPSÜL ... ZİTROGEN 250 MG KAPSÜL , 6 ADET ... AZITRO 250 MG FILM KAPLI TABLET, 6 ADET …
A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Approved
Investigational
A synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver. Prednisone was granted FDA approval on 21 February 1955.
Approved
Vet approved
Matched Products: … PredniSONE Tablets, USP, 20 mg …
Methimazole is a thionamide antithyroid agent that inhibits the synthesis of thyroid hormones.[A184559,A184733,A184694] It was first introduced as an antithyroid agent in 1949 and is now commonly used in the management of hyperthyroidism, particularly in those for whom more aggressive options such as surgery or radioactive iodine therapy are inappropriate.[L8336,L8339]...
Approved
Matched Products: … THYROZOL 20 ... PERİZOL 20 MG FİLM TABLET, 100 ADET ... PERİZOL 20 MG FİLM TABLET, 30 ADET …
Ruxolitinib, formerly known as INCB018424 or INC424, is an anticancer drug and a Janus kinase (JAK) inhibitor. It is a potent and selective inhibitor of JAK1 and JAK2, which are tyrosine kinases involved in cytokine signalling and hematopoiesis. Myeloproliferative neoplasms, such as myelofibrosis and polycythemia vera, are often characterized by...
Approved
Matched Salts cas: … 1092939-16-6
Matched Products: … JAKAVI 20 MG (TABLETS) ... JAKAVI 20 MG TABLET, 168 TABLET ... JAKAVİ 20 MG TABLET, 14 ADET …
Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness. Caffeine is similar in chemical structure to Theophylline and Theobromine.[A187691,L9851] It can be sourced from coffee beans, but also occurs naturally in...
Approved
Matched Mixtures name: … KÜRAMOL TABLET, 20 ADET ... PACOFEN TABLET 20 TABLET ... MEDAFEIN TABLET, 20 ADET …
Matched Products: … CAFEIN® 20 MG/ML ... CAFNEA ® 20 MG / ML ... CITRATO DE CAFEINA 20 MG/ML . SOLUCION ESTERIL …
Valdecoxib was removed from the Canadian, U.S., and E.U. markets in 2005 due to concerns about a possible increased risk of heart attack and stroke.
Approved
Investigational
Withdrawn
Matched Products: … PARALGEN ® 20 TABLETAS ... BEXTRA®20 MG TABLETAS RECUBIERTAS ... VALDYNE 20 MG TABLETAS RECUBIERTAS …
Potassium bicarbonate is a white, crystalline, slightly alkaline and salty substance. It is produced by the passage of carbon dioxide through an aqueous potassium carbonate solution. It is used in medicine as an antacid. It is registered in the FDA under the section of suitable, safe and effective ingredients for...
Approved
Matched Mixtures name: … PRONAT ADVANCE 100 MG+20 MG ORAL SÜSPANSİYON ... REFCON ADVANCE 100 MG + 20 MG/ML ORAL SÜSPANSIYON ... Gaviscon Liquid forte Anis 100 mg/ml + 20 mg/ml Suspension zum Einnehmen …
Matched Products: … Effer-K 20 mEq Unflavored ... Effer-K 20 mEq Orange Cream …
Disorders such as schizophrenia and bipolar disorder can significantly impair mood, cognition, and behavior. These mental illnesses can often be accompanied by comorbidities such as depression and substance abuse, and can significantly impact the quality of life of patients and caregivers. Luckily, several treatment options for psychotic disorders have been...
Approved
Matched Iupac: … 5-{2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl}-6-chloro-2,3-dihydro-1H-indol-2-one …
Matched Products: … ZIPROS 20 ... ZELDOX 20 MG ... ZELDOX 20 MG HARTKAPSELN …
Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up 25% of the mixture. Labetalol is formulated as an injection or tablets to treat hypertension.[L7727,L7730] Labetalol was granted FDA approval on 1 August 1984.
Approved
Matched Salts cas: … 32780-64-6
Matched Products: … DUOBLOQ 100 MG / 20 ML ... TELABELOL 100 MG/ 20 ML ... TRANDATE INJECTION 100 mg/20 ml …
Flunisolide (marketed as AeroBid, Nasalide, Nasarel) is a corticosteroid with anti-inflammatory actions. It is often prescribed as treatment for allergic rhinitis and its principle mechanism of action involves activation of glucocorticoid receptors.
Approved
Investigational
Matched Salts cas: … 77326-96-6
A corticosteroid used topically in the treatment of various skin disorders. It is usually employed as a cream or an ointment, and is also used as a polyethylene tape with an adhesive. (From Martindale, The Extra Pharmacopoeia, 30th ed, p733)
Approved
Vinorelbine is an anti-mitotic chemotherapy drug that is used in the treatment of several types of malignancies, including breast cancer and non-small cell lung cancer (NSCLC) . It was initially approved in the USA in 1990's for the treatment of NSCLC . It is a third-generation vinca alkaloid. The introduction...
Approved
Investigational
Matched Products: … NAVELBINE 20 MG ... NAVELBINE® 20 MG ... Navelbine 20 mg - Kapseln …
Displaying drugs 126 - 150 of 5596 in total