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Displaying drugs 1651 - 1675 of 2451 in total
Oleandomycin
Oleandomycin is a macrolide antibiotic, though it is less effective than erythromycin. It is synthesized from strains of Streptomyces antibioticus.
Vet approved
Matched Categories: … Cytochrome P-450 CYP3A Inhibitors ... Cytochrome P-450 CYP3A4 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) …
Sagopilone
Sagopilone has been used in trials studying the treatment of Melanoma, Neoplasms, CNS Disease, Breast Cancer, and Breast Neoplasms, among others. It is a so-called fully synthetic epothilone and is the first such compound to be in clinical development to combat several forms of cancer. Epothilones are 16-member ring macrolides...
Investigational
Matched Categories: … Cytochrome P-450 CYP3A Inhibitors ... Cytochrome P-450 CYP3A4 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) …
3-Methoxybenzamide
Experimental
Matched Categories: … Enzyme Inhibitors ... Poly(ADP-ribose) Polymerase Inhibitors …
N(G)-Iminoethylornithine
Experimental
Matched Categories: … Enzyme Inhibitors ... Nitric Oxide Synthase, antagonists & inhibitors …
Spebrutinib
Spebrutinib has been used in trials studying the treatment of Rheumatoid Arthritis, Lymphoma, Large B-Cell, Diffuse, and Leukemia Lymphocytic Chronic B-Cell.
Investigational
Matched Categories: … Enzyme Inhibitors ... Protein Kinase Inhibitors …
Rovafovir etalafenamide
Rovafovir etalafenamide is under investigation in clinical trial NCT03472326 (Efficacy of GS-9131 Functional Monotherapy in HIV-1-Infected Adults Failing a Nucleos(t)Ide Reverse Transcriptase Inhibitor-Containing Regimen).
Investigational
Matched Categories: … Enzyme Inhibitors ... Reverse Transcriptase Inhibitors ... Nucleic Acid Synthesis Inhibitors …
Elafin
Elafin is a human protein that is produced naturally in the skin, lung and breast, protecting the respective tissue from destruction by the immune system. Elafin’s ability to block the activity of destructive enzymes that are involved in inflammatory reactions makes it a highly promising active compound for the treatment...
Investigational
Matched Categories: … Enzyme Inhibitors ... Protease Inhibitors …
PF-04991532
PF-04991532 has been used in trials studying the basic science of Diabetes Mellitus, Type 2 Diabetes Mellitus, Diabetes Mellitus, Type 2, and Glucose Metabolism Disorders.
Investigational
Matched Categories: … Enzyme Inhibitors ... Glucokinase, antagonists & inhibitors …
GSK-2636771
GSK2636771 has been used in trials studying the treatment of CANCER, LYMPHOMA, Solid Neoplasm, Recurrent Solid Neoplasm, and Advanced Malignant Neoplasm, among others.
Investigational
Matched Categories: … Enzyme Inhibitors ... Protein Kinase Inhibitors …
R-306465
R306465 has been used in trials studying the treatment of Neoplasms.
Investigational
Matched Categories: … Enzyme Inhibitors ... Histone Deacetylase Inhibitors …
BMS-911543
BMS-911543 has been used in trials studying the treatment of Cancer.
Investigational
Matched Categories: … Janus Kinase 2, antagonists & inhibitors ... Janus Kinases, antagonists & inhibitors …
Naporafenib
Naporafenib is under investigation in clinical trial NCT06346067 (A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With Nras-mutant Melanoma (SEACRAFT-2)).
Investigational
Matched Categories: … Enzyme Inhibitors ... Protein Kinase Inhibitors …
Racecadotril
Racecadotril has been investigated for the basic science and treatment of Diarrhea, Acute Diarrhea, and Acute Gastroenteritis.
Investigational
Matched Categories: … Enzyme Inhibitors ... Protease Inhibitors ... Neprilysin, antagonists & inhibitors …
Crenolanib
Crenolanib is under investigation for the treatment of Diffuse Intrinsic Pontine Glioma and Progressive or Refractory High-Grade Glioma.
Investigational
Matched Categories: … Tyrosine Kinase Inhibitors ... Receptor, Platelet-Derived Growth Factor alpha, antagonists & inhibitors ... Receptor, Platelet-Derived Growth Factor beta, antagonists & inhibitors …
Orbifloxacin
Orbifloxacin is a fluoroquinolone antibiotic. It is marketed by Schering-Plough Animal Health and approved for certain infections in dogs.
Vet approved
Matched Categories: … Cytochrome P-450 CYP1A2 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP1A2 Inhibitors (strength unknown) …
Sarafloxacin
Sarafloxacin is a quinolone antibiotic drug, which was discontinued by its manufacturer, Abbott Laboratories, before receiving approval for use in the US or Canada.
Vet approved
Withdrawn
Matched Categories: … Cytochrome P-450 CYP1A2 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP1A2 Inhibitors (strength unknown) …
Begacestat
Begacestat has been used in trials studying the treatment and basic science of Alzheimer Disease.
Investigational
Matched Categories: … Enzyme Inhibitors ... Gamma Secretase Inhibitors and Modulators …
Cholesterol sulfate
Component of human seminal plasma & spermatozoa.
Experimental
Matched Categories: … Enzyme Inhibitors ... Protease Inhibitors ... Serine Protease Inhibitors …
Lapachone
Lapachone has been used in trials studying the treatment of Cancer, Carcinoma, Advanced Solid Tumors, Head and Neck Neoplasms, and Carcinoma, Squamous Cell.
Investigational
Matched Categories: … Enzyme Inhibitors ... Nucleic Acid Synthesis Inhibitors ... Reverse Transcriptase Inhibitors …
Doramectin
Doramectin is a veterinary drug approved by the Food and Drug Administration for the treatment of parasites such as gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice and mange mites in cattle.
Vet approved
Matched Categories: … Cytochrome P-450 CYP3A Inhibitors ... Cytochrome P-450 CYP3A4 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) …
Methoxy arachidonyl fluorophosphonate
Methoxy arachidonyl fluorophosphonate, commonly referred as MAFP, is an irreversible active site-directed enzyme inhibitor that inhibits nearly all serine hydrolases and serine proteases. It inhibits phospholipase A2 and fatty acid amide hydrolase with special potency, displaying IC50 values in the low-nanomolar range.
Experimental
Matched Categories: … Enzyme Inhibitors ... Phospholipases A, antagonists & inhibitors …
Filibuvir
Filibuvir has been used in trials studying the treatment of Hepatitis, Hepatitis C, and Chronic Hepatitis C.
Investigational
Matched Categories: … RNA Replicase, antagonists & inhibitors ... RNA-Dependent RNA Polymerase, antagonists & inhibitors …
Scriptaid
Scriptaid is a histone deacetylase (HDAC) inhibitor researched for its anti-tumor properties.
Investigational
Matched Categories: … Enzyme Inhibitors ... Histone Deacetylase Inhibitors …
Clorgiline
An antidepressive agent and monoamine oxidase inhibitor related to PARGYLINE.
Experimental
Matched Categories: … Enzyme Inhibitors ... Monoamine Oxidase Inhibitors ... Monoamine Oxidase A Inhibitors …
Displaying drugs 1651 - 1675 of 2451 in total