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Displaying drugs 151 - 175 of 10977 in total
Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength...
Approved
Investigational
Matched Synonyms: … (7R,7AS,12bs)-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methano[1]benzofuro[3,2-e]isoquinoline-7,9-diol …
Matched Salts cas: … 64-31-3 ... 335328-17-1
Matched Products: … MORFİN HİDROKLORÜR OSEL 0,02 G/1 ML ENJEKSİYONLUK ÇÖZELTİ, 3 ADET ... MORFİN HİDROKLORÜR OSEL 0,02 G/1 ML ENJEKSİYONLUK ÇÖZELTİ, 5 ADET ... Oramorph 2 mg/ml Lösung zum Einnehmen …
Perindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration. Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to...
Approved
Matched Synonyms: … (2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]octahydro-1H-indole-2-carboxylic …
Matched Iupac: … (2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]-octahydro-1H-indole-2-carboxylic …
Matched Salts cas: … 1258291-80-3 ... 612548-45-5
Matched Mixtures name: … PERDAPAX 2 MG/0.625 MG TABLET, 30 ADET ... PERIDAY PLUS 2/0.625 TABLET, 30 ADET ... ACEPER PLUS 2 MG/0.625 MG TABLET, 30 ADET …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … COVERSYL ARGININE 5 MG ... อะเซอทิล อาร์จินีน 5 มก. ... COVERSYL 5 MG FILM TABLET, 30 ADET …
A synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver. Prednisone was granted FDA approval on 21 February 1955.
Approved
Vet approved
Matched Iupac: … (1R,3aS,3bS,9aR,9bS,11aS)-1-hydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH …
Matched Products: … ROMEZON DR 2 MG TABLET, 30 ADET ... ROMEZON DR 1 MG TABLET, 30 ADET ... LODOTRA® 1 MG TABLETAS DE CRONO LIBERACION MODIFICADA …
Tropisetron is an indole derivative with antiemetic activity. As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting. Tropisetron appears to be well tolerated with the most frequently reported adverse effect being headache. Extrapyramidal...
Approved
Investigational
Matched Iupac: … (1R,3S,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 1H-indole-3-carboxylate …
Matched Salts cas: … 833482-77-2
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Serotonin 5-HT3 Receptor Antagonists …
Matched Products: … NAVOBAN 5 MG 1 AMPUL ... Navoban 5 mg - Kapseln ... Navoban 5 mg - Ampullen …
Zaleplon is a sedative/hypnotic, mainly used for insomnia. It is known as a nonbenzodiazepine hypnotic. Zaleplon interacts with the GABA receptor complex and shares some of the pharmacological properties of the benzodiazepines. Zaleplon is a schedule IV drug in the United States.
Approved
Illicit
Investigational
Matched Synonyms: … 3'-(3-Cyanopyrazolo(1,5-a)pyrimidin-7-yl)-N-ethylacetanilide …
Matched Iupac: … N-(3-{3-cyanopyrazolo[1,5-a]pyrimidin-7-yl}phenyl)-N-ethylacetamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … SONATA ® 5 MG. CAPSULAS …
Motixafortide is a cyclic peptide hematopoietic stem cell mobilizer used to improve stem cell collection prior to autologous transplantation. Hematopoietic stem cell transplantation (HSCT) is commonly employed in the context of hematologic cancers - high-dose chemotherapy regimens destroy cancerous blood cells, which are then replaced via infusion of the patient's...
Approved
Investigational
Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine.[A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972.[A175390,A190276] Since nifedipine's development, second and third generation dihydropyridines have been developed with slower onsets and longer...
Approved
Matched Synonyms: … 4-(2'-Nitrophenyl)-2,6-dimethyl-1,4-dihydropyridin-3,5-dicarbonsäuredimethylester …
Matched Iupac: … 3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … CALCIANTA 5 ... เนลาปีน 5 ... อาดีปีน 5
Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.
Approved
Matched Synonyms: … 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine …
Matched Iupac: … 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … BARTOLIUM 5 ... CYMALIUM - 5 ... SIBERID 5
Tapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake.[A260721, A36596] Tapentadol was first approved by the FDA on November 20, 2008. The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011....
Approved
Matched Synonyms: … 3-[(1R,2R)-3-(Dimethylamino)-1-ethyl-2-methylpropyl]phenol ... PHENOL, 3-((1R,2R)-3-(DIMETHYLAMINO)-1-ETHYL-2-METHYLPROPYL)- …
Matched Iupac: … 3-[(2R,3R)-1-(dimethylamino)-2-methylpentan-3-yl]phenol …
Imiquimod is an immune response modifier that acts as a toll-like receptor 7 agonist. Imiquimod is commonly used topically to treat warts on the skin of the genital and anal areas. Imiquimod does not cure warts, and new warts may appear during treatment. Imiquimod does not fight the viruses that...
Approved
Investigational
Matched Synonyms: … 1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine ... 4-Amino-1-isobutyl-1H-imidazo(4,5-c)quinoline …
Matched Iupac: … 1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine …
Matched Mixtures name: … Imiquimod 5% / Levocetirizine Dihydrochloride 1% / Niacinamide 2% ... Imiquimod 5% / Levocetirizine Dihydrochloride 1% / Tretinoin 0.05% ... Imiquimod 5% / Niacinamide 4% …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … QUIMARA-1 ... ALDARA™ 5% ... ALDARA CREAM 5% …
Bexagliflozin is a highly specific and potent sodium-glucose co-transporter 2 (SGLT2) inhibitor.[A256408,A256413,L44758] Similar to other SGLT2 inhibitors, bexagliflozin contains three basic moieties: glucose, two benzene rings and a methylene bridge. SGLT2 is responsible for 60% to 90% of renal glucose re-uptake, and unlike other isoforms such as SGLT1, SGLT2 is...
Approved
Investigational
Matched Synonyms: … D-glucitol, 1,5-anhydro-1-C-(4-chloro-3-((4-(2-(cyclopropyloxy)ethoxy)phenyl)methyl)phenyl)-, (1s)- ... (2S,3R,4R,5S,6R)-2-(4-chloro-3-((4-(2-(cyclopropyloxy)ethoxy)phenyl)methyl)phenyl)-6-(hydroxymethyl)tetrahydro …
Matched Iupac: … (2S,3R,4R,5S,6R)-2-(4-chloro-3-{[4-(2-cyclopropoxyethoxy)phenyl]methyl}phenyl)-6-(hydroxymethyl)oxane …
Matched Description: … Its use is not recommended in patients with type 1 diabetes since it may increase their risk of diabetic ... Bexagliflozin is a highly specific and potent sodium-glucose co-transporter 2 (SGLT2) inhibitor. ... L44758] In January 2023, bexagliflozin was approved by the FDA for the treatment of adults with type 2
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Diabetes Mellitus, Type 2, drug therapy ... Sodium-Glucose Transporter 2 Inhibitors ... Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors …
Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as ritonavir for the effective management of HIV-1 infection. As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard HIV therapy.[A2278,A2281] It was initially approved by the FDA in 2006. Darunavir is being...
Approved
Matched Synonyms: … (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-((1S,2R)-1-benzyl-2-hydroxy-3-(N1-isobutylsulfanilamido ... N-((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-benzylpropyl)((1S,2R,5R)-4,6 ... -1-phenylbutan-2-ylcarbamate …
Matched Iupac: … ]-1-phenylbutan-2-yl]carbamate ... (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)4-aminobenzenesulfonamido …
Matched Description: … with other HIV protease inhibitor drugs as well as [ritonavir] for the effective management of HIV-1 ... [L9227] Darunavir is being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible …
Matched Salts cas: … 2281870-65-1 ... 635728-49-3 ... 1447721-06-3
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Bromocriptine mesylate is a semisynthetic ergot alkaloid derivative with potent dopaminergic activity. It inhibits prolactin secretion and may be used to treat dysfunctions associated with hyperprolactinemia. Bromocriptine is also indicated for the management of signs and symptoms of Parkinsonian Syndrome, as well as the treatment of acromegaly. Bromocriptine has been...
Approved
Investigational
Withdrawn
Matched Synonyms: … 2-bromo-α-ergokryptin ... 2-bromo-α-ergocryptine ... 2-Bromo-alpha-ergocryptine …
Matched Iupac: … (4R,7R)-10-bromo-N-[(1S,2S,4R,7S)-2-hydroxy-7-(2-methylpropyl)-5,8-dioxo-4-(propan-2-yl)-3-oxa-6,9-diazatricyclo ... [7.3.0.0^{2,6}]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14 …
Matched Salts cas: … 22260-51-1
Matched Categories: … Adrenergic alpha-2 Receptor Agonists ... Serotonin 5-HT2 Receptor Agonists ... Adrenergic alpha-1 Receptor Agonists ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … Bromocriptine-5 ... PARLODEL 5 MG YAVAŞ SALIMLI KAPSÜL, 28 ADET …
A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.
Approved
Investigational
Matched Synonyms: … 6-Piperidin-1-ylpyrimidine-2,4-diamine 3-oxide ... 2,4-Diamino-6-piperidinopyrimidine 3-oxide …
Matched Iupac: … 2,6-diamino-4-(piperidin-1-yl)pyrimidin-1-ium-1-olate …
Matched Mixtures name: … Betamethasone Dipropionate 0.05% / Minoxidil 5% / Niacinamide 2% / Pentoxifylline 0.5% ... Bakumokon 5% Minoxidil ... Finasteride 0.1% / Minoxidil 5% …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … REGRO LOTION 3% ... MINOXIDIL LOTION 3% w/v ... SW Minoxidil Lotion 3% w/v …
A cardioselective beta-1-adrenergic antagonist with no partial agonist activity.
Approved
Investigational
Matched Synonyms: … 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-2-propanol ... 1-(isopropylamino)-3-[p-(cyclopropylmethoxyethyl)phenoxy]-2-propanol …
Matched Iupac: … 1-{4-[2-(cyclopropylmethoxy)ethyl]phenoxy}-3-[(propan-2-yl)amino]propan-2-ol …
Matched Description: … A cardioselective beta-1-adrenergic antagonist with no partial agonist activity. …
Matched Categories: … Adrenergic beta-1 Receptor Antagonists …
Matched Products: … BETOPTİC S %0,25 OFTALMİK SÜSPANSİYON, 5 ML ... BETOPTIC % 0.5 STERİL GÖZ DAMLASI, ÇÖZELTİ, 5 ML ... BETOPTIC-S % 0.25 STERİL GÖZ DAMLASI, SÜSPANSİYON, 5 ML …
Doxercalciferol is a synthetic vitamin D2 analog that undergoes metabolic activation in vivo to form 1α,25-dihydroxyvitamin D2 (1α,25-(OH)2D2), a naturally occurring, biologically active form of vitamin D2. Doxercalciferol is indicated for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease on dialysis, as well as for the treatment...
Approved
Matched Synonyms: … 1-Hydroxyvitamin D2 ... 1-Hydroxyergocalciferol …
Matched Iupac: … (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-octahydro-1H-inden …
Matched Description: … disease on dialysis, as well as for the treatment of secondary hyperparathyroidism in patients with Stage 3
Hydrochlorothiazide is the most commonly prescribed thiazide diuretic. It is indicated to treat edema and hypertension.[A185138,L8447,L8450] Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors. Many combination products are available containing hydrochlorothiazide and angiotensin converting enzyme inhibitors[L8390,L8423] or angiotensin II receptor blockers.[L7426,L7459] Hydrochlorothiazide was granted FDA...
Approved
Vet approved
Matched Mixtures name: … CARDIK ® 3 160/5/12.5 ... CARDIK ® 3 160/5/12.5 ... CARDIK®3 160/10/12.5 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Axitinib is a second generation tyrosine kinase inhibitor that works by selectively inhibiting vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3). Through this mechanism of action, axitinib blocks angiogenesis, tumour growth and metastases. It is reported to exhibit potency that is 50-450 times higher than that of the first generation...
Approved
Investigational
Matched Synonyms: … N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide …
Matched Iupac: … N-methyl-2-({3-[(E)-2-(pyridin-2-yl)ethenyl]-1H-indazol-6-yl}sulfanyl)benzamide …
Matched Description: … VEGFR-2, VEGFR-3). ... inhibitor that works by selectively inhibiting vascular endothelial growth factor receptors (VEGFR-1, …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Products: … INLYTA (TABLETS 5 MG) ... Axitinib STADA 5 mg Filmtabletten ... Axitinib Sandoz 5 mg – Filmtabletten …
Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970.[A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a primary alcohol group compared to the methyl group of daunorubicin. Although its detailed...
Approved
Investigational
Matched Synonyms: … (1S,3S)-3-glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino ... -8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione ... (8S-cis)-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy …
Matched Iupac: … (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-8-(2-hydroxyacetyl ... )-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione …
Matched Products: … DOXORUBICIN HEXAL 10 MG/5 ML ENJEKSIYON ICIN SOLUSYON ICEREN FLAKON, 1 ADET ... CAELYX 2 MG/ML KONSANTRE İNFUZYON ÇÖZELTİSİ, 1 ADET ... DOXORUBICINA 10 MG/5 ML …
Guanadrel is an antihypertensive agent and postganglionic adrenergic blocking agent.
Approved
Matched Iupac: … N''-({1,4-dioxaspiro[4.5]decan-2-yl}methyl)guanidine …
Matched Salts cas: … 22195-34-2
Articaine is a dental local anesthetic. Articaine is widely used around the world and is the most popular local anesthetic in many European countries.
Approved
Matched Iupac: … methyl 4-methyl-3-[2-(propylamino)propanamido]thiophene-2-carboxylate …
Matched Mixtures name: … MAXİCAİNE 80 MG/2 ML+0,01 MG/2 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL ... ULTRAVER D-S 80 MG + 0,01819 MG / 2 ML ENJEKSİYONLUK ÇÖZELTİ, 20 ADET ... ULTRAVER D-S FORTE 80 MG + 0,03638 MG / 2 ML ENJEKSİYONLUK ÇÖZELTİ, 20 ADET …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Methimazole is a thionamide antithyroid agent that inhibits the synthesis of thyroid hormones.[A184559,A184733,A184694] It was first introduced as an antithyroid agent in 1949 and is now commonly used in the management of hyperthyroidism, particularly in those for whom more aggressive options such as surgery or radioactive iodine therapy are inappropriate.[L8336,L8339]...
Approved
Matched Synonyms: … 1-Methylimidazole-2(3H)-thione …
Matched Iupac: … 1-methyl-2,3-dihydro-1H-imidazole-2-thione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … VELTHROM 5 ... THYROZOL 5 ... THYROZOL TABLET 5 mg …
Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than atenolol, propranolol, or pindolol. Nebivolol and other beta...
Approved
Investigational
Matched Iupac: … 1-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-{[2-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-hydroxyethyl ... ]amino}ethan-1-ol …
Matched Description: … Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other …
Matched Mixtures name: … AMLONEB 5 MG/5 MG TABLET, 30 ADET ... AMLONEB 5 MG/5 MG TABLET, 90 ADET ... VASDAY 5/5/25 MG FILM KAPLI TABLET,90 FILM KAPLI TABLET …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Adrenergic beta-1 Receptor Agonists ... Heterocyclic Compounds, 1-Ring …
Matched Products: … บิลเคท 5 ... NEBIVOLOL 5 MG ... NEBILET TABLET 5 mg …
Homatropine is an anticholinergic drug that acts as an antagonist at muscarinic acetylcholine receptors. It is present in antitussives, under the trade name Hycodan, in combination with hydrocodone (dihydrocodeinone) bitartrate indicated for the symptomatic relief of cough as oral tablets or solutions. Homatropine is included in subtherapeutic amounts as homatropine...
Approved
Matched Iupac: … (1R,3S,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 2-hydroxy-2-phenylacetate …
Matched Products: … Isopto Homatropine 5% ... HOMATRO 2% ... Isopto Homatropine 2% …
Dyphylline is a theophylline derivative with broncho- and vasodilator properties. It is typically used in the management of asthma, cardiac dyspnea, and bronchitis.
Approved
Matched Synonyms: … (1,2-dihydroxy-3-propyl)thiophyllin …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … DIFILIN 400 MG SUPOZITUAR, 5 SUPOZITUAR ... DIFILIN 300 MG/ 3 ML I.M. ENJEKSİYONLUK ÇÖZELTİ, 100 AMPUL ... DIFILIN 300 MG/ 3 ML I.M. ENJEKSİYONLUK ÇÖZELTİ, 200 AMPUL …
Displaying drugs 151 - 175 of 10977 in total