Displaying drugs 151 - 175 of 10666 in total
Lithium citrate
Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Erlotinib
Erlotinib is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase that is used in the treatment of non-small cell lung cancer, pancreatic cancer and several other types of cancer. It is typically marketed under the trade name Tarceva. Erlotinib binds to the epidermal growth factor receptor (EGFR)...
Approved
Investigational
Matched Description: … in the treatment of non-small cell lung cancer, pancreatic cancer and several other types of cancer. ... This finding introduces the potential use of erlotinib in the treatment of JAK2V617F-positive PV and ... form of tyrosine kinase JAK2 found in most patients with polycythemia vera (PV) and a substantial proportion …
Omadacycline
Omadacycline has been used in trials studying the treatment of Bacterial Pneumonia, Bacterial Infections, Community-Acquired Infections, and Skin Structures and Soft Tissue Infections. Omadacycline represents a significant advance over the well-known tetracycline family, and has been shown to be highly effective in animal models at treating increasingly problematic, clinically prevalent...
Approved
Investigational
Matched Description: … Omadacycline has been used in trials studying the treatment of Bacterial Pneumonia, Bacterial Infections ... gram-negative, atypical and anaerobic bacteria, including those resistant to currently available classes of ... significant advance over the well-known tetracycline family, and has been shown to be highly effective in …
Matched Categories: … combinations of tetracyclines …
Matched Categories: … combinations of tetracyclines …
Eprosartan
Eprosartan is an angiotensin II receptor antagonist used to treat hypertension. It performs 2 actions on the renin angiotensin system. By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs. By inhibiting norepinephrine production, blood pressure is further reduced.
Approved
Matched Description: … By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs …
Cinoxacin
Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections.
Approved
Investigational
Withdrawn
Matched Synonyms: … 5-Ethyl-8-oxo-5,8-dihydro-1,3-dioxa-5,6-diaza-cyclopenta[b]naphthalene-7-carboxylic acid …
Matched Description: … Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections …
Matched Description: … Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections …
Vandetanib
Vandetanib is an oral once-daily kinase inhibitor of tumour angiogenesis and tumour cell proliferation with the potential for use in a broad range of tumour types.
On April 6 2011, vandetanib was approved by the FDA to treat nonresectable, locally advanced, or metastatic medullary thyroid cancer in adult patients.
Approved
Matched Synonyms: … N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-((1-methyl-4-piperidinyl)methoxy)-4-quinazolinamine ... N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine …
Matched Iupac: … N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine …
Matched Description: … with the potential for use in a broad range of tumour types. ... Vandetanib is an oral once-daily kinase inhibitor of tumour angiogenesis and tumour cell proliferation ... approved by the FDA to treat nonresectable, locally advanced, or metastatic medullary thyroid cancer in …
Matched Iupac: … N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine …
Matched Description: … with the potential for use in a broad range of tumour types. ... Vandetanib is an oral once-daily kinase inhibitor of tumour angiogenesis and tumour cell proliferation ... approved by the FDA to treat nonresectable, locally advanced, or metastatic medullary thyroid cancer in …
Poa compressa pollen
Poa compressa pollen is the pollen of the Poa compressa plant. Poa compressa pollen is mainly used in allergenic testing.
Approved
Matched Description: … Poa compressa pollen is mainly used in allergenic testing. ... Poa compressa pollen is the pollen of the Poa compressa plant. …
Matched Mixtures name: … Mixture of Standardized and Non-Standardized Inland Grasses ... Mixture of Twenty-Two Standardized and Non-Standardized Grasses ... Mixture of Standardized and Non-Standardized Coastal Grasses …
Matched Mixtures name: … Mixture of Standardized and Non-Standardized Inland Grasses ... Mixture of Twenty-Two Standardized and Non-Standardized Grasses ... Mixture of Standardized and Non-Standardized Coastal Grasses …
Moxidectin
Moxidectin is a potent, broad-spectrum endectocide (antiparasitic that is active against endo- and ecto-parasites) with activity against nematodes, insects, and acari. It was first used in cattle followed by an approved use in general animals. It is a semi-synthetic methoxine derivative of nemadectin which is a 16-member pentacyclic lactone of...
Approved
Investigational
Vet approved
Matched Iupac: … ,13',22'-tetramethyl-6-(4-methylpent-2-en-2-yl)-3',7',19'-trioxaspiro[oxane-2,6'-tetracyclo[15.6.1.1^ ... (1'R,2R,4E,4'S,5S,6S,8'R,10'E,13'R,14'E,16'E,20'R,21'R,24'S)-21',24'-dihydroxy-4-(methoxyimino)-5,11' …
Matched Description: … Moxidectin differs by the absence of a disaccharide moiety on carbon 13, a substituted olefinic side ... 13, 2018. ... It was first used in cattle followed by an approved use in general animals. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Description: … Moxidectin differs by the absence of a disaccharide moiety on carbon 13, a substituted olefinic side ... 13, 2018. ... It was first used in cattle followed by an approved use in general animals. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Rimegepant
Rimegepant is an oral antagonist of the CGRP receptor developed by Biohaven Pharmaceuticals. It received FDA approval on February 27, 2020 for the acute treatment migraine headache, and was subsequently approved by the European Commission in April 2022 for both the treatment and prevention of migraines. While several parenteral antagonists...
Approved
Investigational
Matched Description: … [atogepant] in 2021. ... acute treatment migraine headache,[L11974] and was subsequently approved by the European Commission in ... April 2022 for both the treatment and prevention of migraines. …
Matched Categories: … Calcitonin Gene-Related Peptide (CGRP) Antagonists ... Calcitonin Gene-Related Peptide Receptor Antagonists …
Matched Categories: … Calcitonin Gene-Related Peptide (CGRP) Antagonists ... Calcitonin Gene-Related Peptide Receptor Antagonists …
Methocarbamol
Methocarbamol was developed in the early 1950s as a treatment for muscle spasticity and the associated pain.[A178441,A178450] It is a guaiacol glyceryl ether. Methocarbamol tablets and intramuscular injections are prescription medicines indicated in the United States as an adjunct to rest, physical therapy, and other measures for the relief of...
Approved
Vet approved
Matched Description: … the United States as an adjunct to rest, physical therapy, and other measures for the relief of discomforts ... Methocarbamol was developed in the early 1950s as a treatment for muscle spasticity and the associated ... A178450]
Methocarbamol tablets and intramuscular injections are prescription medicines indicated in …
Sodium citrate
Sodium citrate is the sodium salt of citric acid. It is white, crystalline powder or white, granular crystals, slightly deliquescent in moist air, freely soluble in water,
practically insoluble in alcohol. Like citric acid, it has a sour taste.
From the medical point of view, it is used as alkalinizing...
Approved
Investigational
Matched Description: … soluble in water,
practically insoluble in alcohol. ... Sodium citrate is the sodium salt of citric acid. ... It has been indicated for the treatment of metabolic acidosis. …
Matched Mixtures name: … Reveos Select CPD/AS-5 Red Cell Preservative For Collection Of Blood ... ADSOL Red Cell Preservation Solution System in Plastic Container (PL 146 Plastic) ... ADSOL Red Cell Preservation Solution System in Plastic Container (PL 146 Plastic) …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Mixtures name: … Reveos Select CPD/AS-5 Red Cell Preservative For Collection Of Blood ... ADSOL Red Cell Preservation Solution System in Plastic Container (PL 146 Plastic) ... ADSOL Red Cell Preservation Solution System in Plastic Container (PL 146 Plastic) …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Tepotinib
Tepotinib is a MET tyrosine kinase inhibitor intended to treat a variety of MET-overexpressing solid tumors. It was originally developed in partnership between EMD Serono and the University of Texas M.D. Anderson Cancer Center in 2009 and has since been investigated in the treatment of neuroblastoma, gastric cancers, non-small cell...
Approved
Investigational
Matched Description: … MET_ exon 14 skipping alterations. ... Anderson Cancer Center in 2009 and has since been investigated in the treatment of neuroblastoma,[A228053 ... critical role, both directly and indirectly, in the growth and proliferation of tumors in which it is …
Dostarlimab
Dostarlimab is an IgG4 humanized monoclonal antibody targeted against the human programmed death receptor-1 (PD-1). PD-1 receptors are found on T-cells and, when activated, serve to inhibit immune responses - some cancers leverage this system by overexpressing PD-1 ligands, thereby effectively inhibiting the anti-tumor immune response that would typically attempt...
Approved
Investigational
Matched Description: … in the same month. ... resulted in all twelve patients exhibiting a complete clinical response. ... cancers, including those of the skin, lung, kidneys, and liver. …
Iobenguane
Synthetic guanethidine derivative that locates phaeochromocytomas and neuroblastomas. The radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that metabolize noradrenaline. Iodine 123 is a cyclotron-produced radionuclide that decays to Te 123 by electron capture. Images are produced by a I123 MIBG scintigraphy. FDA approved...
Approved
Investigational
Matched Description: … The radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that …
Matched Salts cas: … 77679-27-7 ... 87862-25-7 …
Matched Categories: … Diagnostic Uses of Chemicals ... Compounds used in a research, industrial, or household setting …
Matched Salts cas: … 77679-27-7 ... 87862-25-7 …
Matched Categories: … Diagnostic Uses of Chemicals ... Compounds used in a research, industrial, or household setting …
Tafamidis
Tafamidis and tafamidis meglumine (FX-1006A) are benzoxazole derivatives developed by FoldRX. Tafamidis is structurally similar to diflusinal. Tafamidis was granted an EMA market authorisation on 16 November 2011 and FDA approval on 3 May 2019.
Approved
Investigational
Matched Salts cas: … 951395-08-7 …
Burosumab
Burosumab (KRN23) is an entirely human monoclonal IgG1 antibody that binds excess fibroblast growth factor 23 (FGF23) and has been successfully tested in clinical trials in children with X-linked hypophosphatemic rickets .
The U.S. Food and Drug Administration approved Crysvita (burosumab) in April 2018. This is the first drug approved...
Approved
Investigational
Matched Description: … X-linked hypophosphatemia causes low circulating levels of phosphorus in the blood. ... children ages 1 year and older with X-linked hypophosphatemia (XLH), which is a rare, inherited form of ... Food and Drug Administration approved Crysvita (burosumab) in April 2018. …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Ibandronate
Ibandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to zoledronic acid, minodronic acid, and risedronic acid.[A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis.[L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss in dogs. Ibandronate was granted FDA...
Approved
Investigational
Matched Description: … in dogs. ... [L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Products: … BONVIVA 3MG/3ML ILO IN FER ... OSTIVEA 3mg/3ml Solution for IV Injection in Pre-filled Syringe ... Ibandronsäure ratiopharm 3 mg Injektionslösung in einer Fertigspritze …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Products: … BONVIVA 3MG/3ML ILO IN FER ... OSTIVEA 3mg/3ml Solution for IV Injection in Pre-filled Syringe ... Ibandronsäure ratiopharm 3 mg Injektionslösung in einer Fertigspritze …
Flurbiprofen
Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis....
Approved
Investigational
Matched Description: … Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, …
Matched Products: … Strepsils 8,75 mg/Dosis Spray zur Anwendung in der Mundhöhle, Lösung ... Strepsils Honig & Zitrone 8,75 mg/Dosis Spray zur Anwendung in der Mundhöhle, Lösung ... Lemocin Flurbiprofen 8,75 mg/Dosis Spray zur Anwendung in der Mundhöhle, Lösung …
Matched Products: … Strepsils 8,75 mg/Dosis Spray zur Anwendung in der Mundhöhle, Lösung ... Strepsils Honig & Zitrone 8,75 mg/Dosis Spray zur Anwendung in der Mundhöhle, Lösung ... Lemocin Flurbiprofen 8,75 mg/Dosis Spray zur Anwendung in der Mundhöhle, Lösung …
Infigratinib
Infigratinib is a pan-fibroblast growth factor receptor (FGFR) kinase inhibitor. By inhibiting the FGFR pathway, which is often aberrated in cancers such as cholangiocarcinoma, infigratinib suppresses tumour growth. Cholangiocarcinoma is the most common primary malignancy affecting the biliary tract and the second most common primary hepatic malignancy. Infitratinib is a...
Approved
Investigational
Matched Description: … By inhibiting the FGFR pathway, which is often aberrated in cancers such as cholangiocarcinoma, infigratinib ... [A198963] Infitratinib is a pan-FGFR inhibitor, as it is an ATP-competitive inhibitor of all four FGFR ... previously treated, unresectable locally advanced or metastatic cholangiocarcinoma in adults with a …
Gaxilose
Gaxilose has been used in trials studying the diagnostic of Lactose Intolerance.
Approved
Investigational
Matched Description: … Gaxilose has been used in trials studying the diagnostic of Lactose Intolerance. …
Methionine
A sulfur containing essential amino acid that is important in many body functions. It is a chelating agent for heavy metals.
Approved
Nutraceutical
Matched Description: … A sulfur containing essential amino acid that is important in many body functions. …
Matched Mixtures name: … Aminosyn II 7% M In 10% Dextrose(dual Chamber) ... Numeta G 13 % E Emulsion zur Infusion ... Aminosyn 7% …
Matched Mixtures name: … Aminosyn II 7% M In 10% Dextrose(dual Chamber) ... Numeta G 13 % E Emulsion zur Infusion ... Aminosyn 7% …
Cianidanol
An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms.
Approved
Withdrawn
Matched Description: … An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin …
Holcus lanatus pollen
Holcus lanatus pollen is the pollen of the Holcus lanatus plant. Holcus lanatus pollen is mainly used in allergenic testing.
Approved
Matched Description: … Holcus lanatus pollen is mainly used in allergenic testing. ... Holcus lanatus pollen is the pollen of the Holcus lanatus plant. …
Matched Mixtures name: … Mixture of Standardized and Non-Standardized Coastal Grasses ... Mixture of Twenty-Two Standardized and Non-Standardized Grasses …
Matched Mixtures name: … Mixture of Standardized and Non-Standardized Coastal Grasses ... Mixture of Twenty-Two Standardized and Non-Standardized Grasses …
Polatuzumab vedotin
Polatuzumab vedotin is a CD79b-directed antibody-drug conjugate that delivers monomethyl auristatin E (MMAE), an anti-mitotic agent, to cancer cells. The drug consists of three components - a humanized immunoglobulin G1 (IgG1) monoclonal antibody specific for human CD79b (polatuzumab), MMAE, and protease-cleavable linker called maleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl (mc-vc-PAB) that covalently attaches MMAE to...
Approved
Investigational
Matched Description: … [L6658] The drug consists of three components - a humanized immunoglobulin G1 (IgG1) monoclonal antibody …
Influenza A virus A/California/7/2009 X-179A (H1N1) antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Investigational
Matched Name: … Influenza A virus A/California/7/2009 X-179A (H1N1) antigen (formaldehyde inactivated) …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …
Displaying drugs 151 - 175 of 10666 in total