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Displaying drugs 151 - 175 of 10683 in total

Formoterol

Formoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001. It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic mixture of its active (R;R)- and inactive (S;S)-enantiomers....
Approved
Investigational
Matched Description: … Formoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was ... first approved for use in the United States in 2001. ... of action (2-3 minutes), which is at least as fast as [salbutamol], combined with a long duration of …
Matched Products: … CYCLOCAPS FORMOTERO12UG+IN ... FORMATRIS 6UG NOV IN+2PX60 ... FORMATRIS 6UG NOV IN+3PX60 …

Omadacycline

Omadacycline has been used in trials studying the treatment of Bacterial Pneumonia, Bacterial Infections, Community-Acquired Infections, and Skin Structures and Soft Tissue Infections. Omadacycline represents a significant advance over the well-known tetracycline family, and has been shown to be highly effective in animal models at treating increasingly problematic, clinically prevalent...
Approved
Investigational
Matched Description: … Omadacycline has been used in trials studying the treatment of Bacterial Pneumonia, Bacterial Infections ... gram-negative, atypical and anaerobic bacteria, including those resistant to currently available classes of ... significant advance over the well-known tetracycline family, and has been shown to be highly effective in …
Matched Categories: … combinations of tetracyclines …

Lactitol

Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from lactose. It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet as table sugar (i.e. sucrose). Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other non-absorbable disaccharides...
Approved
Investigational
Matched Description: … the treatment of hepatic encephalopathy in patients with cirrhosis. ... chronic idiopathic constipation in February 2020. ... [A190918] It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Calendula officinalis flower

Calendula officinalis flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … Calendula officinalis flower is a plant/plant extract used in some OTC (over-the-counter) products. …

Moxidectin

Moxidectin is a potent, broad-spectrum endectocide (antiparasitic that is active against endo- and ecto-parasites) with activity against nematodes, insects, and acari. It was first used in cattle followed by an approved use in general animals. It is a semi-synthetic methoxine derivative of nemadectin which is a 16-member pentacyclic lactone of...
Approved
Investigational
Vet approved
Matched Iupac: … ,13',22'-tetramethyl-6-(4-methylpent-2-en-2-yl)-3',7',19'-trioxaspiro[oxane-2,6'-tetracyclo[15.6.1.1^ ... (1'R,2R,4E,4'S,5S,6S,8'R,10'E,13'R,14'E,16'E,20'R,21'R,24'S)-21',24'-dihydroxy-4-(methoxyimino)-5,11' …
Matched Description: … Moxidectin differs by the absence of a disaccharide moiety on carbon 13, a substituted olefinic side ... 13, 2018. ... It was first used in cattle followed by an approved use in general animals. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Sodium citrate

Sodium citrate is the sodium salt of citric acid. It is white, crystalline powder or white, granular crystals, slightly deliquescent in moist air, freely soluble in water, practically insoluble in alcohol. Like citric acid, it has a sour taste. From the medical point of view, it is used as alkalinizing...
Approved
Investigational
Matched Description: … soluble in water, practically insoluble in alcohol. ... Sodium citrate is the sodium salt of citric acid. ... It has been indicated for the treatment of metabolic acidosis. …
Matched Mixtures name: … Reveos Select CPD/AS-5 Red Cell Preservative For Collection Of Blood ... ADSOL Red Cell Preservation Solution System in Plastic Container (PL 146 Plastic) ... ADSOL Red Cell Preservation Solution System in Plastic Container (PL 146 Plastic) …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Norepinephrine

Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is...
Approved
Matched Description: … projection system in the brain arising from the locus ceruleus. ... Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse ... It is also found in plants and is used pharmacologically as a sympathomimetic. …
Matched Products: … Norepinephrine Bitartrate In Sodium Chloride ... Norepinephrine Bitartrate In 5% Dextrose Injection …

Tafamidis

Tafamidis and tafamidis meglumine (FX-1006A) are benzoxazole derivatives developed by FoldRX. Tafamidis is structurally similar to diflusinal. Tafamidis was granted an EMA market authorisation on 16 November 2011 and FDA approval on 3 May 2019.
Approved
Investigational
Matched Salts cas: … 951395-08-7 …

Tepotinib

Tepotinib is a MET tyrosine kinase inhibitor intended to treat a variety of MET-overexpressing solid tumors. It was originally developed in partnership between EMD Serono and the University of Texas M.D. Anderson Cancer Center in 2009 and has since been investigated in the treatment of neuroblastoma, gastric cancers, non-small cell...
Approved
Investigational
Matched Description: … MET_ exon 14 skipping alterations. ... Anderson Cancer Center in 2009 and has since been investigated in the treatment of neuroblastoma,[A228053 ... critical role, both directly and indirectly, in the growth and proliferation of tumors in which it is …

Chlorhexidine

Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms. It is one of the most common skin and mucous membrane antiseptic agents in use today. The molecule itself is a cationic bis-guanide consisting of...
Approved
Vet approved
Withdrawn
Matched Description: … [L11512] It is one of the most common skin and mucous membrane antiseptic agents in use today. ... [L11518,L11512,A190453] Chlorhexidine was developed in the UK by Imperial Chemical Industries in the ... of this product. …
Matched Mixtures name: … easyangin Spray zur Anwendung in der Mundhöhle ... Cathejell Diphenhydramin 1 % / Chlorhexidin 0,05 % - Gel (in Tuben) …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Chlorhexamed 1% - Gel zur Anwendung in der Mundhöhle ... Chlorhexamed Direkt 1 % - Gel zur Anwendung in der Mundhöhle ... Chlorhexamed forte 2 mg/ml Dentallösung zur Anwendung in der Zahnarztpraxis …

Lasofoxifene

Lasofoxifene is a non-steroidal 3rd generation selective estrogen receptor modulator (SERM) that selectively binds to both ERα and ERβ with high affinity. It is a naphthalene derivative marketed for prevention and treatment of osteoporosis and for the treatment of vaginal atrophy. It was initially developed as Oporia by Pfizer as...
Approved
Investigational
Matched Description: … of vaginal atrophy. ... oral lasofoxifene in the USA. ... with a newly submitted New Drug Application in 2008. …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Iobenguane

Synthetic guanethidine derivative that locates phaeochromocytomas and neuroblastomas. The radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that metabolize noradrenaline. Iodine 123 is a cyclotron-produced radionuclide that decays to Te 123 by electron capture. Images are produced by a I123 MIBG scintigraphy. FDA approved...
Approved
Investigational
Matched Description: … The radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that …
Matched Salts cas: … 77679-27-7 ... 87862-25-7 …
Matched Categories: … Diagnostic Uses of Chemicals ... Compounds used in a research, industrial, or household setting …

Propofol

Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness,...
Approved
Investigational
Vet approved
Matched Description: … Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory ... using a combination of medications. ... Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia …
Matched Products: … FRESOFOL MCT/LCT EMULSION FOR INJECTION OR INFUSION IN PRE-FILLED SYRINGE 2% ... Propofol "Fresenius" 1 % mit MCT Emulsion zur Injektion oder Infusion in einer Fertigspritze ... Propofol "Fresenius" 2 % mit MCT Emulsion zur Injektion oder Infusion in einer Fertigspritze …

Gaxilose

Gaxilose has been used in trials studying the diagnostic of Lactose Intolerance.
Approved
Investigational
Matched Description: … Gaxilose has been used in trials studying the diagnostic of Lactose Intolerance. …

Influenza A virus A/California/7/2009 X-179A (H1N1) antigen (formaldehyde inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Investigational
Matched Name: … Influenza A virus A/California/7/2009 X-179A (H1N1) antigen (formaldehyde inactivated) …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …

Infigratinib

Infigratinib is a pan-fibroblast growth factor receptor (FGFR) kinase inhibitor. By inhibiting the FGFR pathway, which is often aberrated in cancers such as cholangiocarcinoma, infigratinib suppresses tumour growth. Cholangiocarcinoma is the most common primary malignancy affecting the biliary tract and the second most common primary hepatic malignancy. Infitratinib is a...
Approved
Investigational
Matched Description: … By inhibiting the FGFR pathway, which is often aberrated in cancers such as cholangiocarcinoma, infigratinib ... [A198963] Infitratinib is a pan-FGFR inhibitor, as it is an ATP-competitive inhibitor of all four FGFR ... previously treated, unresectable locally advanced or metastatic cholangiocarcinoma in adults with a …

Cianidanol

An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms.
Approved
Withdrawn
Matched Description: … An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin …

Demeclocycline

A tetracycline analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time.
Approved
Matched Synonyms: … 6-demethyl-7-chlorotetracycline ... 7-chloro-6-demethyltetracycline ... [4S-(4α,4aα,5aα,6β,12aα)]-7-chloro-4-(dimethylamino)1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy …
Matched Iupac: … (4S,4aS,5aS,6S,12aS)-7-chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene …
Matched Description: … A tetracycline analog having a 7-chloro and a 6-methyl. ... it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of …
Matched Categories: … combinations of tetracyclines …

Copanlisib

Copanlisib is a selective pan-Class I phosphoinositide 3-kinase (PI3K) inhibitor with preferential activity against the alpha and delta isoforms. PI3K, a lipid kinase that activates downstream signalling pathways involved in cell survival and growth, that exists in different isoforms and is often overexpressed in hematological malignancies. Copanlisib was granted accelerated...
Approved
Investigational
Matched Synonyms: … 2-AMINO-N-(7-METHOXY-8-(3-(MORPHOLIN-4-YL)PROPOXY)-2,3-DIHYDROIMIDAZO(1,2-C)QUINAZOLIN-5-YL(PYRIMIDINE ... 2-AMINO-N-(7-METHOXY-8-(3-MORPHOLIN-4-YLPROPOXY)-2,3-DIHYDROIMIDAZO(1,2-C)QUINAZOLIN-5-YL)PYRIMIDINE- ... 5-PYRIMIDINECARBOXAMIDE, 2-AMINO-N-(2,3-DIHYDRO-7-METHOXY-8-(3-(4-MORPHOLINYL)PROPOXY)IMIDAZO(1,2-C)QUINAZOLIN …
Matched Iupac: … 2-amino-N-{7-methoxy-8-[3-(morpholin-4-yl)propoxy]-2H,3H-imidazo[1,2-c]quinazolin-5-yl}pyrimidine-5-carboxamide …
Matched Description: … of follicular lymphoma. ... , that exists in different isoforms and is often overexpressed in hematological malignancies. ... PI3K, a lipid kinase that activates downstream signalling pathways involved in cell survival and growth …
Matched Salts cas: … 1402152-13-9 …

Burosumab

Burosumab (KRN23) is an entirely human monoclonal IgG1 antibody that binds excess fibroblast growth factor 23 (FGF23) and has been successfully tested in clinical trials in children with X-linked hypophosphatemic rickets . The U.S. Food and Drug Administration approved Crysvita (burosumab) in April 2018. This is the first drug approved...
Approved
Investigational
Matched Description: … X-linked hypophosphatemia causes low circulating levels of phosphorus in the blood. ... children ages 1 year and older with X-linked hypophosphatemia (XLH), which is a rare, inherited form of ... Food and Drug Administration approved Crysvita (burosumab) in April 2018. …
Matched Categories: … Drugs for Treatment of Bone Diseases …

Phentolamine

Phentolamine is a reversible, non-selective alpha-adrenergic blocker that induces vasodilation. While initially introduced to the market for the treatment of hypertension, this clinical use was halted due to cardiovascular and gastrointestinal adverse effects with the prolonged use of large oral doses of phentolamine.[A261781, A261786] It has several therapeutic uses, including...
Approved
Matched Description: … of phentolamine. ... prevention of norepinephrine-induced extravasation, diagnosis of pheochromocytoma, reversal of soft-tissue ... anesthesia, and treatment of pharmacologically-induced mydriasis. …

Methionine

A sulfur containing essential amino acid that is important in many body functions. It is a chelating agent for heavy metals.
Approved
Nutraceutical
Matched Description: … A sulfur containing essential amino acid that is important in many body functions. …
Matched Mixtures name: … Aminosyn II 7% M In 10% Dextrose(dual Chamber) ... Numeta G 13 % E Emulsion zur Infusion ... Aminosyn 7% …

Rotigotine

Rotigotine (Neupro) is a non-ergoline dopamine agonist indicated for the treatment of Parkinson's disease (PD) and restless legs syndrome (RLS) in Europe and the United States. It is formulated as a once-daily transdermal patch which provides a slow and constant supply of the drug over the course of 24 hours....
Approved
Matched Description: … However, all Neupro patches in the United States and some of Europe were recalled in 2008 due to delivery ... In 1998 Aderis licensed worldwide development and commercialization rights to Schwarz Pharma of Germany ... over the course of 24 hours. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Polatuzumab vedotin

Polatuzumab vedotin is a CD79b-directed antibody-drug conjugate that delivers monomethyl auristatin E (MMAE), an anti-mitotic agent, to cancer cells. The drug consists of three components - a humanized immunoglobulin G1 (IgG1) monoclonal antibody specific for human CD79b (polatuzumab), MMAE, and protease-cleavable linker called maleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl (mc-vc-PAB) that covalently attaches MMAE to...
Approved
Investigational
Matched Description: … [L6658] The drug consists of three components - a humanized immunoglobulin G1 (IgG1) monoclonal antibody …

Progesterone

Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy. A low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss . Progesterone is used in various contraceptive preparations to prevent ovulation...
Approved
Vet approved
Matched Iupac: … acetyl-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7- …
Matched Description: … , embryo implantation, and the successful establishment of pregnancy. ... acetate], [Dydrogesterone] and [Hydroxyprogesterone] entries for information on various other forms of ... ], [A175612] as well as in other formulations to promote and support pregnancy. …
Matched Mixtures name: … Minoxidil 7% / Progesterone 0.1% ... Minoxidil 7% / Progesterone 0.1% / Tretinoin 0.025% ... Fluocinolone Acetonide 0.01% / Minoxidil 7% / Progesterone 0.1% …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Matched Products: … ENJEKSİYONLUK ÇÖZELTİ, 7 ADET ... Gesterol In Oil-liq Im 50mg/ml ... Progedex 25 mg Injektionslösung in einer Fertigspritze …
Displaying drugs 151 - 175 of 10683 in total