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Displaying drugs 151 - 175 of 12106 in total

Ledipasvir

Ledipasvir is a direct acting antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Matched Description: … Lack of significant side effects and short duration of therapy is a considerable advantage over older ... C, as they exhibit a high barrier to the development of resistance [A19593]. ... Ledipasvir is a direct acting antiviral (DAA) medication used as part of combination therapy to treat …
Matched Categories: … Antivirals for treatment of HCV infections …

Darunavir

Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as ritonavir for the effective management of HIV-1 infection. As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard HIV therapy.[A2278,A2281] It was initially approved by the FDA in 2006. Darunavir is being...
Approved
Matched Description: … for the effective management of HIV-1 infection. ... Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as [ritonavir] ... [L9227] As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard …
Matched Categories: … combinations of sulfonamides ... Antivirals used in combination for the treatment of HIV infections …

Simeprevir

Simeprevir is a hepatitis C virus (HCV) NS3/4A protease inhibitor indicated in patient's with HCV genotype 1 for the treatment of chronic hepatitis C virus (HCV) infection. HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United...
Approved
Matched Description: … Broad use of simeprevir occurred when it was used in combination with a newer drug, [DB08934]. ... with the intent to cure, or achieve a sustained virologic response (SVR), after 12 weeks of daily therapy ... Inhibiting HCV NS3/4A protease in a potent and highly specific manner, simeprevir is a direct-acting …
Matched Categories: … combinations of sulfonamides ... Antivirals for treatment of HCV infections …

Ascorbic acid

A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic...
Approved
Nutraceutical
Matched Description: … A six carbon compound related to glucose. ... Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic …
Matched Mixtures name: … Herbs of Gold B Complex Plus Softgel ... Hot Lemon Relief for Symptoms Of Cold and Flu ... Hot Lemon Relief for Symptoms Of Cough and Cold …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Vitamine C 500 A L'orange ... Appeton A to Z Kid"s Vitamin C 30mg (Strawberry) ... APPETON A TO Z KID` S VITAMIN C 30MG TABLET (ORANGE) …

Etonogestrel

Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel. The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in 2001.
Approved
Investigational
Matched Iupac: … -1-ethynyl-1-hydroxy-10-methylidene-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … active metabolite of progestin desogestrel. ... Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Phenoxymethylpenicillin

Phenoxymethylpenicillin is a narrow spectrum antibiotic also commonly referred to as Penicillin V or Penicillin VK. It is a phenoxymethyl analog of Penicillin G, or benzylpenicillin. An orally active naturally penicillin, phenoxymethylpenicillin is used to treat mild to moderate infections in the respiratory tract, skin, and soft tissues caused by...
Approved
Vet approved
Matched Description: … [A178609] It is a phenoxymethyl analog of Penicillin G, or [benzylpenicillin]. ... Phenoxymethylpenicillin is a narrow spectrum antibiotic also commonly referred to as Penicillin V or ... or other acquired valvular heart disease when they undergo dental procedures and surgical procedures of …
Matched Categories: … combinations of penicillins …

Ethynodiol diacetate

A synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive. Although etynodiol or ethynodiol are sometimes used as a synonym for ethynodiol diacetate, what is usually being referred to is actually ethynodiol diacetate and not ethynodiol (which is a separate drug that has never been...
Approved
Matched Iupac: … -7-(acetyloxy)-1-ethynyl-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … A synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive ... being referred to is actually ethynodiol diacetate and not ethynodiol (which is a separate drug that ... Although etynodiol or ethynodiol are sometimes used as a synonym for ethynodiol diacetate, what is usually …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Chlorothiazide

A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)
Approved
Vet approved
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. …
Matched Categories: … combinations of sulfonamides …

Gestrinone

Gestrinone, also known as ethylnorgestrienone, is a synthetic steroid of the 19-nortestosterone group that is marketed in Europe, Australia, and Latin America, though not the United States or Canada, and is used primarily in the treatment of endometriosis. Gestrinone was developed in the early 1970s and was tested clinically as...
Approved
Matched Iupac: … (1R,3aS,3bS,11aS)-11a-ethyl-1-ethynyl-1-hydroxy-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,11aH-cyclopenta[a]phenanthren …
Matched Description: … Gestrinone, also known as ethylnorgestrienone, is a synthetic steroid of the 19-nortestosterone group ... , and Latin America, though not the United States or Canada, and is used primarily in the treatment of ... Gestrinone was developed in the early 1970s and was tested clinically as a weekly oral contraceptive …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Becaplermin

Becaplermin is produced by recombinant DNA technology by insertion of the gene for the B chain of platelet derived growth factor (PDGF) into the yeast, Saccharomyces cerevisiae. Becaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical polypeptide chains that are bound together...
Approved
Investigational
Matched Description: … Becaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical ... Becaplermin is produced by recombinant DNA technology by insertion of the gene for the B chain of platelet …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers …

Butorphanol

A synthetic morphinan analgesic with narcotic antagonist action. It is used in the management of severe pain.
Approved
Illicit
Vet approved
Matched Description: … It is used in the management of severe pain. ... A synthetic morphinan analgesic with narcotic antagonist action. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Nalbuphine

A narcotic used as a pain medication. It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors. Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States.
Approved
Matched Description: … A narcotic used as a pain medication. ... Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Ombitasvir

Ombitasvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Investigational
Matched Description: … Lack of significant side effects and short duration of therapy is a considerable advantage over older ... Ombitasvir is a direct acting antiviral medication used as part of combination therapy to treat chronic ... Ombitasvir is an inhibitor of NS5A, a protein essential for viral replication and virion assembly [FDA …
Matched Categories: … Antivirals for treatment of HCV infections …

Estetrol

Naturally or synthetically produced steroid estrogens have a wide range of pharmaceutical uses ranging from hormonal contraception to the treatment of menopausal symptoms. Estetrol (E4) is a native estrogen occurring naturally during pregnancy, but can be synthesized from a plant source and used for contraception. It is more potent and...
Approved
Investigational
Matched Iupac: … (1R,2R,3R,3aS,3bR,9bS,11aS)-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene …
Matched Description: … The combination of drospirenone and estetrol offers a new choice with a favourable safety profile for ... Naturally or synthetically produced steroid estrogens have a wide range of pharmaceutical uses ranging ... combination of [drospirenone] and estetrol. …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Citalopram

Citalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs.[A261316,A14720] Citalopram enhances serotonergic transmission through the...
Approved
Matched Description: … It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing ... SSRIs) widely used to treat the symptoms of depression. ... [A261316,A14720] Specifically, it has a very minimal effect on dopamine and norepinephrine transportation …
Matched Categories: … Monoamine Oxidase A Substrates ... Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Flucloxacillin

Antibiotic analog of cloxacillin.
Approved
Investigational
Matched Description: … Antibiotic analog of [cloxacillin]. …
Matched Categories: … combinations of penicillins …

Oxytetracycline

A tetracycline analog isolated from the actinomycete streptomyces rimosus and used in a wide variety of clinical conditions.
Approved
Investigational
Vet approved
Matched Description: … of clinical conditions. ... A tetracycline analog isolated from the actinomycete streptomyces rimosus and used in a wide variety …
Matched Categories: … combinations of tetracyclines …

Sulfasalazine

Sulfasalazine is an anti-inflammatory drug structurally related to salicylates and other non-steroidal anti-inflammatory drugs. It is indicated for managing inflammatory diseases such as ulcerative colitis and rheumatoid arthritis (RA).[L39065, A255582] Metabolized by intestinal bacteria, sulfasalazine is broken down into mesalazine and sulfapyridine, 2 compounds that carry out the main pharmacological...
Approved
Matched Description: … [A255582] Sulfasalazine fell out of favor as the drug of choice for RA due to poorly designed clinical ... is not FDA-recommmended for treatment of Crohn's disease. ... into [mesalazine] and [sulfapyridine], 2 compounds that carry out the main pharmacological activity of …
Matched Categories: … combinations of sulfonamides …

Methylphenobarbital

A barbiturate that is metabolized to phenobarbital. It has been used for similar purposes, especially in epilepsy, but there is no evidence mephobarbital offers any advantage over phenobarbital.
Approved
Matched Description: … A barbiturate that is metabolized to phenobarbital. …
Matched Categories: … combinations of barbiturates …

Sofosbuvir

Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the...
Approved
Matched Description: … Lack of significant side effects and short duration of therapy is a considerable advantage over older ... Hepatitis C, as they exhibit a high barrier to the development of resistance [A19593]. ... Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy …
Matched Categories: … Antivirals for treatment of HCV infections …

Nafcillin

A semi-synthetic antibiotic related to penicillin, Naficillin is a narrow-spectrum beta-lactam antibiotic drug. It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections caused by strains that are resistant to other penicillins, except those caused by MRSA. It may be used as a first-line therapy in...
Approved
Investigational
Matched Description: … It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections ... A semi-synthetic antibiotic related to penicillin, Naficillin is a narrow-spectrum beta-lactam antibiotic ... It may be used as a first-line therapy in Methicillin-Sensitive *Staphylococcus aureus* infections [A20360 …
Matched Categories: … combinations of penicillins …

Methyltestosterone

A synthetic anabolic steroid used for treating men with testosterone deficiency or similar androgen replacement therapies. Also, has antineoplastic properties and so has been used secondarily in women with advanced breast cancer. Methyltestosterone is a schedule III drug in the US.
Approved
Matched Iupac: … ,11aS)-1-hydroxy-1,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Methyltestosterone is a schedule III drug in the US. ... A synthetic anabolic steroid used for treating men with testosterone deficiency or similar androgen replacement …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Amoxapine

Amoxapine, the N-demethylated derivative of the antipsychotic agent loxapine, is a dibenzoxazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, amoxapine does not affect mood or arousal, but may cause sedation....
Approved
Matched Description: … See toxicity section below for a complete listing of side effects. ... Amoxapine, the N-demethylated derivative of the antipsychotic agent loxapine, is a dibenzoxazepine-derivative ... In depressed individuals, amoxapine exerts a positive effect on mood. …
Matched Categories: … Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Benzatropine

Benztropine, with the chemical formula 3alpha-diphenylmethoxytropane, is a tropane-based dopamine inhibitor used for the symptomatic treatment of Parkinson's disease. It is a combination molecule between a tropane ring, similar to cocaine, and a diphenyl ether from the dialkylpiperazines determined to be a dopamine uptake inhibitor since 1970. The generation of...
Approved
Matched Description: … of a chlorine substituent in the para position in one of the phenyl rings produces an increased potency ... for dopamine uptake inhibition as well as a decreased inhibition of serotonin and norepinephrine. ... It is a combination molecule between a tropane ring, similar to cocaine, and a diphenyl ether from the …
Matched Categories: … Ethers of Tropine or Tropine Derivatives …

Pentobarbital

A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA...
Approved
Investigational
Vet approved
Matched Description: … A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) ... induction than for sedation but, like similar agents, may lose its effectiveness by the second week of …
Matched Categories: … combinations of barbiturates …
Displaying drugs 151 - 175 of 12106 in total