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Displaying drugs 151 - 175 of 9353 in total
One of the penicillins which is resistant to penicillinase but susceptible to a penicillin-binding protein. It is inactivated by gastric acid so administered by injection.
Approved
Investigational
Matched Description: … One of the penicillins which is resistant to penicillinase but susceptible to a penicillin-binding protein …
Matched Categories: … combinations of penicillins …
Sarecycline is a semi-synthetic derivative of tetracycline that was initially discovered by Paratek Pharmaceuticals from Boston, MA but then licensed to Warner Chilcott of Rockaway, NJ in July of 2007 . After completing various phase-II and phase-III trials demonstrating its effectiveness in treating moderate to severe facial acne vulgaris [A39993,...
Approved
Investigational
Matched Description: … from Boston, MA but then licensed to Warner Chilcott of Rockaway, NJ in July of 2007 [A40005]. ... inflammatory lesions of non-nodular moderate to severe acne vulgaris in patients nine years of age and ... of young adults aged 12 to 25 years globally - with the possibility of permanent physical and mental …
Matched Categories: … combinations of tetracyclines …
Temocillin has been investigated in Infection, Liver Dysfunction, and Urinary Tract Infection.
Approved
Investigational
Matched Categories: … combinations of penicillins …
Phthalylsulfathiazole is a broad spectrum antibiotic which is part of the drug class, sulfonamides. It was used as an antibiotic for bowel surgery, and for infections of the colon .
Approved
Matched Description: … It was used as an antibiotic for bowel surgery, and for infections of the colon [A175006]. ... Phthalylsulfathiazole is a broad spectrum antibiotic which is part of the drug class, sulfonamides. …
Matched Categories: … combinations of sulfonamides …
Gallium (Ga) 68 prostate-specific membrane antigen (PSMA)-11, or Ga-68 gozetotide, is a radiopharmaceutical agent used to identify and assess prostate-specific membrane antigen (PSMA)-positive lesions in adult men with prostate cancer during positron emission tomography (PET). Prostate cancer is one of the most commonly diagnosed cancers among men in Western countries...
Approved
Matched Description: … [L43542] In December of the same year, the drug was fully authorized by the EMA. ... [L26981] Prostate cancer is one of the most commonly diagnosed cancers among men in Western countries ... Human Use (CHMP) recommended Ga-68 gozetotide be granted marketing authorization for the diagnosis of
Matched Categories: … Diagnostic Uses of Chemicals …
Protriptyline hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, protriptyline does not affect mood or arousal, but may cause sedation. In depressed individuals, protriptyline exerts a positive...
Approved
Matched Description: … Protriptyline may be used for the treatment of depression. ... TCAs are potent inhibitors of serotonin and norepinephrine reuptake. ... See toxicity section below for a complete listing of side effects. …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Latanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular pressure (IOP). It was initially approved by the FDA in 1998. Latanoprost is the first topical prostaglandin F2 alpha analog used for glaucoma treatment. It has been found to be well-tolerated and its use...
Approved
Investigational
Matched Description: … Latanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular …
Methadone is a potent synthetic analgesic that works as a full µ-opioid receptor (MOR) agonist and N-methyl-d-aspartate (NMDA) receptor antagonist. As a full MOR agonist, methadone mimics the natural effects of the body's opioids, endorphins, and enkephalins through the release of neurotransmitters involved in pain transmission. It also has a...
Approved
Matched Description: … , and a long duration of action. ... Provision of OAT is often combined with education about harm reduction including use of clean needles ... The intention of substitution of illicit opioids with the long-acting opioids used in OAT is to prevent …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Dexchlorpheniramine is the S-enantiomer of chlorpheniramine which is a 1st generation anti-histamine. Dexchlorpheniramine has more pharmacological activity than the R and so is more potent than the racemic mixture.
Approved
Matched Description: … Dexchlorpheniramine is the S-enantiomer of chlorpheniramine which is a 1st generation anti-histamine. ... Dexchlorpheniramine has more pharmacological activity than the R and so is more potent than the racemic …
Persistent forms of tuberculosis (TB) have proven to be a major cause of global morbidity and mortality and a cause for significant concern. Research in recent years has been geared toward the development of novel therapies that target persistent forms of this disease, which have shown resistance to standard therapy...
Approved
Matched Description: … Persistent forms of tuberculosis (TB) have proven to be a major cause of global morbidity and mortality ... forms of this disease, which have shown resistance to standard therapy regimens. ... Research in recent years has been geared toward the development of novel therapies that target persistent …
Matched Categories: … Drugs for Treatment of Tuberculosis …
Sodium zirconium cyclosilicate is approved as the trade product Lokelma developed by AstraZeneca - an insoluble, non-absorbed sodium zirconium silicate, formulated as a powder for oral suspension that acts as a highly selective potassium removing agent. It is administered orally and is odorless, tasteless, and stable at room temperature. Approval...
Approved
Investigational
Matched Description: … time to achieving normal potassium levels in the blood was 2.2 hours, with 92% of patients achieving ... [L2933] Approval of the medication is supported by data from three double-blind, placebo-controlled trials ... and two open-label trials which showed that the onset of action was approximately 1.0 hour and the median …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Syagrus romanzoffiana pollen is the pollen of the Syagrus romanzoffiana plant. Syagrus romanzoffiana pollen is mainly used in allergenic testing.
Approved
Matched Description: … Syagrus romanzoffiana pollen is the pollen of the Syagrus romanzoffiana plant. …
A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic...
Approved
Nutraceutical
Matched Mixtures name: … Formula R Tab ... Herbs of Gold B Complex Plus Softgel ... Hot Lemon Relief for Symptoms Of Cold and Flu …
Matched Products: … ไฮซี(R) 100 ... ไฮซี (R)100 สวีทเลทส์ ... R-CORBACID 100 MG / 1ML SOLUCION INYECTABLE …
Eplerenone, an aldosterone receptor antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of the negative regulatory feedback of aldosterone on renin secretion. The resulting increased plasma renin activity and aldosterone circulating levels do not overcome the effects of...
Approved
Matched Iupac: … methyl (1'R,2R,2'S,9'R,10'R,11'S,15'S,17'R)-2',15'-dimethyl-5,5'-dioxo-18'-oxaspiro[oxolane-2,14'-pentacyclo …
Matched Description: … the negative regulatory feedback of aldosterone on renin secretion. ... shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of ... resulting increased plasma renin activity and aldosterone circulating levels do not overcome the effects of
Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.
Approved
Investigational
Matched Categories: … combinations of penicillins …
A second-line antitubercular agent that inhibits mycolic acid synthesis. It also may be used for treatment of leprosy. (From Smith and Reynard, Textbook of Pharmacology, 1992, p868)
Approved
Matched Description: … It also may be used for treatment of leprosy. ... (From Smith and Reynard, Textbook of Pharmacology, 1992, p868) …
Matched Categories: … Drugs for Treatment of Tuberculosis …
Pivmecillinam is a mecillinam prodrug, a pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa. It is active against gram-negative organisms and used as for amdinocillin. [PubChem]
Approved
Matched Description: … Pivmecillinam is a mecillinam prodrug, a pivaloyloxymethyl ester of amdinocillin that is well absorbed …
Matched Categories: … combinations of penicillins …
Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Sevoflurane is an ether inhalation anesthetic agent used to induce and maintain general anesthesia. It is a volatile, non-flammable compound with a low solubility profile and blood/gas partition coefficient. Sevoflurane was patented in 1972, was approved for clinical use in Japan in 1990, and approved by the FDA in 1996....
Approved
Vet approved
Matched Description: … The hemodynamic and respiratory depressive effects of sevoflurane are well tolerated, and most patients ... A249910] Therefore, it can be used for inhalational induction in adults and children for a wide variety of
Matched Products: … SOJOURN(R)(SEVOFLURANE, USP) INHALATION ANESTHETIC …
Pyridoxine is the 4-methanol form of vitamin B6, an important water-soluble vitamin that is naturally present in many foods. As its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required for normal functioning of many biological systems within the body. While many plants and microorganisms are...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … biochemical reactions, including the metabolism of amino acids and glycogen, the synthesis of nucleic ... Pyridoxine is used medically for the treatment of vitamin B6 deficiency and for the prophylaxis of isoniazid-induced ... of pyridoxine in the above-mentioned metabolic functions). …
Matched Mixtures name: … Formula R Tab ... MIOBION(R) 1000 JERINGA PRELLENADA ... Harvest Of Values All B Complex Tab …
Matched Categories: … Drugs for Treatment of Tuberculosis …
A tetracycline analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time.
Approved
Matched Description: … it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of
Matched Categories: … combinations of tetracyclines …
Technetium Tc-99m exametazime is a radiopharmaceutical sold under the trade name Ceretec used in the detection of altered regional cerebral perfusion in stroke and other cerebrovascular diseases. It can also be used for the labelling of leukocytes to localise intra-abdominal infections and inflammatory bowel disease. Exametazime, also known as hexamethylpropyleneamine...
Approved
Matched Description: … Tc-99m exametazime is a radiopharmaceutical sold under the trade name Ceretec used in the detection of ... It can also be used for the labelling of leukocytes to localise intra-abdominal infections and inflammatory …
Matched Categories: … Diagnostic Uses of Chemicals …
Technetium Tc-99m (99mTc) succimer, also known as technetium Tc-99m dimercaptosuccinic acid (DMSA), is a radioactive diagnostic agent used to evaluate functional renal tissue and tubular function in patients with renal parenchymal disorders. It works by binding to the cortical region of the kidneys. Technetium Tc-99m succimer is used with gamma...
Approved
Matched Description: … [L40558] The use of technetium Tc-99m succimer for the detection of kidney cortical defects was first ... It works by binding to the cortical region of the kidneys. …
Matched Categories: … Diagnostic Uses of Chemicals …
Secnidazole is a second-generation 5-nitroimidazole antimicrobial agent. It is structurally related to other 5-nitroimidazoles, including DB00916 and DB00911, but displays improved oral absorption and a longer terminal elimination half-life than other drugs in this class. Secnidazole is selective against many anaerobic Gram-positive and Gram-negative bacteria as well as protozoa. Once...
Approved
Matched Description: … A245508] In September 2017, FDA approved secnidazole under the market name Solosec for the treatment of
Matched Products: … GIAFAR(R) 1 G TABLETAS ... DAKSOL(R)1 G TABLETAS …
Displaying drugs 151 - 175 of 9353 in total