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Displaying drugs 1776 - 1800 of 5869 in total
Encorafenib
Encorafenib, also known as BRAFTOVI, is a kinase inhibitor. Encorafenib inhibits BRAF gene, which encodes for B-raf protein, which is a proto-oncogene involved in various genetic mutations. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which impacts cell division, differentiation, and secretion. Mutations in this gene,...
Approved
Investigational
Matched Iupac: … methyl N-[(2S)-1-({4-[3-(5-chloro-2-fluoro-3-methanesulfonamidophenyl)-1-(propan-2-yl)-1H-pyrazol-4-yl …
Bicisate
Bicisate, also known as ethyl cysteinate dimer (ECD), is a N,N'-1,2-ethylene-di-yl-bis-L-cysteinate diethyl ester. It is used in conjunction with technetium Tc99m as a tracer to measure cerebral blood flow with single-photon emission computed tomography (SPECT). The complex of bicisate and technetium Tc99m as a kit was developed by Lantheus Medcl...
Approved
Investigational
Meradimate
Meradimate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different products as a UV filter. It is currently required to be named as meradimate in all FDA approved OTC products. Meradimate is approved by the FDA and Health Canada to be used as an...
Approved
Matched Iupac: … 5-methyl-2-(propan-2-yl)cyclohexyl 2-aminobenzoate …
Matched Description: … Meradimate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different …
Matched Mixtures name: … Eezy Sun SPF 50 ... Eezy Pro SPF 50 …
Matched Description: … Meradimate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different …
Matched Mixtures name: … Eezy Sun SPF 50 ... Eezy Pro SPF 50 …
Meningococcal polysaccharide vaccine group W-135
Meningococcal group W-135 polysaccharide is group-specific polysaccharide antigens extracted and purified from Neisseria meningitidis serogroup W-135. N. meningitidis is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia. It is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup W-135.
Approved
Experimental
Investigational
Matched Mixtures name: … MENCEVAX ACWY 0,5 ML SC ENJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN ÇOK DOZLU FLAKON, 50 ADET ... MENACTRA 0,5 ML IM ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 5 ADET ... MENVEO 0,5ML IM ENJEKSIYONLUK COZEZELTI HAZIRLAMAK ICIN LIYOFILIZE TOZ ICEREN 5 FLAKON …
Entrectinib
Entrectinib is a tropomyosin receptor tyrosine kinase (TRK) TRKA, TRKB, TRKC, proto-oncogene tyrosine-protein kinase ROS1, and anaplastic lymphoma kinase (ALK) inhibitor. It was approved by the FDA in August 2019 for use in the treatment of ROS1-positive metastatic non-small cell lung cancer and NTRK gene fusion positive solid tumors. Entrectinib's...
Approved
Investigational
Matched Synonyms: … N-[5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl]-4-(4-methylpiperazin-1-yl)-2-(oxan-4-ylamino)benzamide …
Matched Iupac: … N-{5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl}-4-(4-methylpiperazin-1-yl)-2-[(oxan-4-yl)amino]benzamide …
Matched Iupac: … N-{5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl}-4-(4-methylpiperazin-1-yl)-2-[(oxan-4-yl)amino]benzamide …
Turoctocog alfa
Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally occurring B-domain. Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any...
Approved
Investigational
Sulfamethoxazole
Sulfamethoxazole is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis in susceptible bacteria. It is generally given in combination with trimethoprim, which inhibits a sequential step in bacterial folic acid synthesis - these agents work synergistically to block two consecutive steps in the biosynthesis of nucleic acids and...
Approved
Matched Synonyms: … 3-Sulfanilamido-5-methylisoxazole ... 3-(p-Aminophenylsulfonamido)-5-methylisoxazole ... 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide …
Matched Iupac: … 4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzene-1-sulfonamide …
Matched Mixtures name: … .)/5 ML. ... TRIMETOPRIMA 40 MG/5 ML SULFAMETOXAZOL 200MG/5 ML SUSPENSION ... CO-TRIPIRIM 5 ML 1 AMPUL …
Matched Iupac: … 4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzene-1-sulfonamide …
Matched Mixtures name: … .)/5 ML. ... TRIMETOPRIMA 40 MG/5 ML SULFAMETOXAZOL 200MG/5 ML SUSPENSION ... CO-TRIPIRIM 5 ML 1 AMPUL …
Linzagolix
Linzagolix is a non-peptide, selective antagonist of the gonadotropin-releasing hormone (GnRH) receptor. It has been studied for the treatment of estrogen-dependent conditions such as uterine fibroids and endometriosis.[A253642,A253647] It is similar to other GnRH receptor antagonists like cetrorelix, relugolix, and elagolix.
Uterine fibroids occur in >70% of women of reproductive...
Approved
Matched Synonyms: … (3,4-d)pyrimidine-5-carboxylic acid ... Thieno(3,4-d)pyrimidine-5-carboxylic acid, 3-(5-((2,3-difluoro-6-methoxyphenyl)methoxy)-2-fluoro-4-methoxyphenyl ... 3-(5-((2,3-difluoro-6-methoxyphenyl)methoxy)-2-fluoro-4-methoxyphenyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno …
Matched Iupac: … -d]pyrimidine-5-carboxylic acid ... 3-{5-[(2,3-difluoro-6-methoxyphenyl)methoxy]-2-fluoro-4-methoxyphenyl}-2,4-dioxo-1H,2H,3H,4H-thieno[3,4 …
Matched Iupac: … -d]pyrimidine-5-carboxylic acid ... 3-{5-[(2,3-difluoro-6-methoxyphenyl)methoxy]-2-fluoro-4-methoxyphenyl}-2,4-dioxo-1H,2H,3H,4H-thieno[3,4 …
Meningococcal polysaccharide vaccine group A
Meningococcal group A polysaccharide is group-specific polysaccharide antigens extracted and purified from Neisseria meningitidis serogroup A. N. meningitidis is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia. It is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup A.
Approved
Experimental
Investigational
Matched Mixtures name: … MENCEVAX ACWY 0,5 ML SC ENJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN ÇOK DOZLU FLAKON, 50 ADET ... MENACTRA 0,5 ML IM ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 5 ADET ... MENVEO 0,5ML IM ENJEKSIYONLUK COZEZELTI HAZIRLAMAK ICIN LIYOFILIZE TOZ ICEREN 5 FLAKON …
Rosoxacin
Rosoxacin is a quinolone derivative antibiotic for the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients. Rosoxacin is known to be effective against penicillin resistant strains and is a single dose orally administered drug, which avoids all complications of parenteral administration seen with...
Approved
Investigational
Matched Synonyms: … 1-ethyl-1,4-dihydro-4-oxo-7-(4-pyridyl)-3-quinolinecarboxylic acid …
Matched Iupac: … 1-ethyl-4-oxo-7-(pyridin-4-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Iupac: … 1-ethyl-4-oxo-7-(pyridin-4-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Cefaclor
Semisynthetic, broad-spectrum antibiotic derivative of cephalexin.
Approved
Matched Synonyms: … 3-Chloro-7-D-(2-phenylglycinamido)-3-cephem-4-carboxylic acid …
Matched Iupac: … (6R,7R)-7-[(2R)-2-amino-2-phenylacetamido]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic …
Matched Salts cas: … 70356-03-5 …
Matched Products: … ./5มล.) ... ./5มล.) ... DISTACLOR 125 MG/5 ML …
Matched Iupac: … (6R,7R)-7-[(2R)-2-amino-2-phenylacetamido]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic …
Matched Salts cas: … 70356-03-5 …
Matched Products: … ./5มล.) ... ./5มล.) ... DISTACLOR 125 MG/5 ML …
Terazosin
Terazosin is a quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and hypertension[FDA Label] . Terazosin blocks adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and the prostate .
Approved
Matched Salts cas: … 70024-40-7 …
Matched Mixtures name: … Hytrin-7 Tabs 1mg-7 Tabs 2mg-14 Tabs 5mg ... Hytrin-7 Tabs 1mg-7 Tabs 2mg-14 Tabs 5mg ... Hytrin-7 Tabs 1mg-7 Tabs 2mg-14 Tabs 5mg …
Matched Products: … Terazosin-5 ... HYTRIN TABLET 5 mg ... Urocard 5 mg Tabletten …
Matched Mixtures name: … Hytrin-7 Tabs 1mg-7 Tabs 2mg-14 Tabs 5mg ... Hytrin-7 Tabs 1mg-7 Tabs 2mg-14 Tabs 5mg ... Hytrin-7 Tabs 1mg-7 Tabs 2mg-14 Tabs 5mg …
Matched Products: … Terazosin-5 ... HYTRIN TABLET 5 mg ... Urocard 5 mg Tabletten …
Tegaserod
Novartis' brand name Zelnorm (tegaserod) had originally received approval from the US FDA in 2002 for the treatment of irritable bowel syndrome with constipation (IBS-C).[L5918,F4229] It was, however, voluntarily withdrawn from widespread use in the US market in 2007 after concerns arose over the possibility that tegaserod could potentially cause...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-(((5-Methoxyindol-3-yl)methylene)amino)-3-pentylguanidine …
Matched Iupac: … N'-[(E)-[(5-methoxy-1H-indol-3-yl)methylidene]amino]-N-pentylguanidine …
Matched Description: … the only therapy for IBS-C that possesses the unique mechanism of action of acting on serotonin-4 (5- …
Matched Categories: … Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists ... Serotonin 5-HT2C Receptor Antagonists …
Matched Iupac: … N'-[(E)-[(5-methoxy-1H-indol-3-yl)methylidene]amino]-N-pentylguanidine …
Matched Description: … the only therapy for IBS-C that possesses the unique mechanism of action of acting on serotonin-4 (5- …
Matched Categories: … Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists ... Serotonin 5-HT2C Receptor Antagonists …
Potassium nitrate
Potassium nitrate is an inorganic salt with a chemical formula of KNO3. It is a natural source of nitrate and has been used as a constituent for several different purposes, including food preservatives, fertilizers, tree stump removal, rocket propellants, and fireworks. Potassium nitrate is a common active ingredient in toothpaste,...
Approved
Meningococcal polysaccharide vaccine group C
Meningococcal group C polysaccharide is group-specific polysaccharide antigens extracted and purified from Neisseria meningitidis serogroup C. N. meningitidis is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia. It is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup C.
Approved
Experimental
Investigational
Matched Mixtures name: … MENCEVAX ACWY 0,5 ML SC ENJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN ÇOK DOZLU FLAKON, 50 ADET ... MENACTRA 0,5 ML IM ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 5 ADET ... MENVEO 0,5ML IM ENJEKSIYONLUK COZEZELTI HAZIRLAMAK ICIN LIYOFILIZE TOZ ICEREN 5 FLAKON …
Hexaminolevulinate
Hexaminolevulinate is an optical imaging drug. In solution form it is instilled intravesically for use with photodynamic blue light cystoscopy as an adjunct to white light cystoscopy. On May 28, 2010, the U.S. Food and Drug Administration (FDA) granted approval for hexaminolevulinate hydrochloride (Cysview for Intravesical Solution, Photocure ASA), as...
Approved
Matched Synonyms: … Hexyl 5-amino-4-oxopentanoate hydrochloride ... Hexyl(5-amino-4-oxopentanoat)-hydrochlorid ... Pentanoic acid, 5-amino-4-oxo-, hexyl ester, hydrochloride …
Matched Iupac: … hexyl 5-amino-4-oxopentanoate …
Matched Salts cas: … 140898-91-5 …
Matched Iupac: … hexyl 5-amino-4-oxopentanoate …
Matched Salts cas: … 140898-91-5 …
Moexipril
Moexipril is a non-sulfhydryl containing precursor of the active angiotensin-converting enzyme (ACE) inhibitor moexiprilat. It is used to treat high blood pressure (hypertension). It works by relaxing blood vessels, causing them to widen. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.
Approved
Matched Salts cas: … 82586-52-5 …
Influenza A virus A/South Australia/55/2014 live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Benoxaprofen
The use of benoxaprofen, formerly marketed as Oraflex tablets, was associated with fatal cholestatic jaundice among other serious adverse reactions. The holder of the approved application voluntarily withdrew Oraflex tablets from the market on August 5, 1982.
Approved
Withdrawn
Matched Synonyms: … (1)-2-(4-Chlorophenyl)benzoxazole-5-propionic acid ... 2-(4-chlorophenyl)-α-methyl-5-benzoxazoleacetic acid ... 2-(p-chlorophenyl)-α-methyl-5-benzoxazoleacetic acid …
Matched Iupac: … 2-[2-(4-chlorophenyl)-1,3-benzoxazol-5-yl]propanoic acid …
Matched Description: … The holder of the approved application voluntarily withdrew Oraflex tablets from the market on August 5, …
Matched Iupac: … 2-[2-(4-chlorophenyl)-1,3-benzoxazol-5-yl]propanoic acid …
Matched Description: … The holder of the approved application voluntarily withdrew Oraflex tablets from the market on August 5, …
Tegafur
Tegafur (INN, BAN, USAN) is a prodrug of DB00544 (5-FU), an antineoplastic agent used as the treatment of various cancers such as advanced gastric and colorectal cancers. It is a pyrimidine analogue used in combination therapies as an active chemotherapeutic agent in conjunction with DB09257 and DB03209, or along with...
Approved
Investigational
Matched Synonyms: … 1-(2-Tetrahydrofuryl)-5-fluorouracil …
Matched Iupac: … 5-fluoro-1-(oxolan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … high concentrations of 5-FU at a lower dose of tegafur [L933]. ... Tegafur (INN, BAN, USAN) is a prodrug of [DB00544] (5-FU), an antineoplastic agent used as the treatment ... Tegafur is usually given in combination with other drugs that enhance the bioavailability of the 5-FU …
Matched Iupac: … 5-fluoro-1-(oxolan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … high concentrations of 5-FU at a lower dose of tegafur [L933]. ... Tegafur (INN, BAN, USAN) is a prodrug of [DB00544] (5-FU), an antineoplastic agent used as the treatment ... Tegafur is usually given in combination with other drugs that enhance the bioavailability of the 5-FU …
Fosamprenavir
Fosamprenavir is a prodrug of amprenavir, an inhibitor of human immunodeficiency virus (HIV) protease.
Approved
Matched Salts cas: … 226700-80-7 …
Clenbuterol
A substituted phenylaminoethanol that has beta-2 adrenomimetic properties at very low doses. It is used as a bronchodilator in asthma.
Approved
Investigational
Vet approved
Matched Mixtures name: … AMBROXOL 15 MG+ CLENBUTEROL 10 MCG /5 ML …
Thimerosal
Thiomersal (INN), commonly known in the U.S. as thimerosal, is an organomercury compound. This compound is a well-established and widely used antiseptic and antifungal agent.
Developed in 1927, thimerosal has been and is still being used as a preservative in some cosmetics, topical pharmaceuticals, and biological drug products, which includes...
Approved
Etomidate
Imidazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular system. It has been proposed as an induction anesthetic.
Approved
Matched Synonyms: … (+)-ethyl 1-(α-methylbenzyl)imidazole-5-carboxylate ... R-(+)-ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate ... (R)-(+)-1-(α-methylbenzyl)imidazole-5-carboxylic acid ethyl ester …
Matched Iupac: … ethyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate …
Matched Products: … HYPNOMIDATE 2 MG /10 ML AMPUL, 5 ADET …
Matched Iupac: … ethyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate …
Matched Products: … HYPNOMIDATE 2 MG /10 ML AMPUL, 5 ADET …
Glatiramer
Glatiramer acetate is a mix of synthetic polypeptides that includes L-glutamic acid, L-alanine, L-tyrosine, and L-lysine at an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. Since glatiramer acetate is a heterogeneous drug, there is limited information about its physicochemical properties. Originally, glatiramer acetate was designed as a...
Approved
Investigational
Matched Salts cas: … 147245-92-9 …
Displaying drugs 1776 - 1800 of 5869 in total