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Displaying drugs 201 - 225 of 11524 in total

Trolamine salicylate

Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid. It is a topical analgesic used for temporary relief of minor pain associated with arthritis, simple backache, muscle strains, sprains, and bruises. Unlike other topical analgesics, trolamine...
Approved
Matched Description: … Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid ... It is a topical analgesic used for temporary relief of minor pain associated with arthritis, simple backache ... trolamine salicylate is an inhibitor of cyclo-oxygenase (COX) enzymes with no reported selectivity towards a …
Matched Products: … Antiphlogistine Rub A-535 No Odour Fmla Ont …

Doxorubicin

Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970.[A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a primary alcohol group compared to the methyl group of daunorubicin. Although its detailed...
Approved
Investigational
Matched Description: … Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius ... A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a ... A257614] Thanks to its efficacy and broad effect, doxorubicin was approved by the FDA in 1974 to treat a …
Matched Categories: … BSEP/ABCB11 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … DOXORRUBICINA CLORHIDRATO 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE. …

Avelumab

Avelumab is a human IgG1 lambda monoclonal antibody that binds programmed cell death ligand-1 (PD-L1) to block its interaction with its receptors found on T cells and antigen-presenting cells. Avelumab was first approved by the FDA on March 23, 2017. On September 18 and December 18 of the same year,...
Approved
Investigational
Matched Description: … Avelumab is a human IgG1 lambda monoclonal antibody that binds programmed cell death ligand-1 (PD-L1) …

Flavin mononucleotide

A coenzyme for a number of oxidative enzymes including NADH DEHYDROGENASE. It is the principal form in which RIBOFLAVIN is found in cells and tissues.
Approved
Investigational
Matched Description: … A coenzyme for a number of oxidative enzymes including NADH DEHYDROGENASE. …
Matched Mixtures name: … Alsimine W Vitamins A D ... Tonicol Et A-D-C Ampoules/comprimes …

Levamlodipine

Levamlodipine, also known as S-amlodipine, is a pharmacologically active enantiomer of amlodipine, an antihypertensive medication. Levamlodipine belongs to the dihydropyridine group of calcium channel blockers. This medication was first marketed in Russia and India before being granted FDA approval. The names S-amlodipine and levamlodipine may be used interchangeably as both...
Approved
Investigational
Matched Description: … Levamlodipine, also known as S-amlodipine, is a pharmacologically active enantiomer of [amlodipine], ... [L10833] As a racemic mixture, amlodipine contains (R) and (S)-amlodipine isomers, but only (S)-amlodipine …

Iodine

Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.[A3413,A192153,A192156,A192159]
Approved
Investigational
Matched Mixtures name: … One A Day Tab ... Complete One A Day Tab ... Complete One-A-day - Tab …

Bepridil

A long-acting, non selective, calcium channel blocker with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist. It is no longer marketed in the United States, as it has been implicated in causing...
Approved
Withdrawn
Matched Description: … A long-acting, non selective, calcium channel blocker with significant anti-anginal activity. ... It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist. …

Cedazuridine

Myelodysplastic syndromes (MDS) are a group of hematopoietic neoplasms that give rise to variable cytopenias progressing to secondary acute myeloid leukemia (sAML), which is invariably fatal if untreated.[A215082, A215092, A215097] Hypomethylating agents such as decitabine and azacitidine are used to treat MDS through inducing DNA hypomethylation and apoptosis of cancerous...
Approved
Investigational
Matched Description: … Myelodysplastic syndromes (MDS) are a group of hematopoietic neoplasms that give rise to variable cytopenias ... [A215107, A215112, A215117, A215127] Cedazuridine is a fluorinated tetrahydrouridine derivative specifically …

Coagulation factor VIIa Recombinant Human

Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the extrinsic pathway of the coagulation cascade. NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.
Approved
Matched Description: … NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. ... Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form …

Rotavirus vaccine

Rotavirus commonly infects children and infants causing severe diarrhea and vomiting leading to potentially fatal dehydration. Two rotavirus vaccines are available for the prevention of rotavirus gastroenteritis, Rotateq and Rotarix. Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. Rotarix is a live attenuated vaccine containing the...
Approved
Matched Description: … Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. ... [L1116] Rotarix is a live attenuated vaccine containing the 89-12 human strain. …
Matched Salts name: … Human Rotavirus A type G1P(8) strain RIX4414 live antigen ... Human Rotavirus A type G1P7(5) strain WI79 live antigen ... Human Rotavirus A type G2P7(5) strain SC2 live antigen ... Human Rotavirus A type G4P7(5) strain BRB live antigen ... Human Rotavirus A type G3P7(5) strain WI78 live antigen …

Tetracycline

Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site. It also binds to some extent to the...
Approved
Vet approved
Withdrawn
Matched Description: … Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria ... It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit ... for the use of all liquid oral drug products formulated for pediatric use containing tetracycline in a …
Matched Products: … Tetracycline 3 percent a First Aid Antibiotic …

Tetryzoline

Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral alpha (α)-adrenergic properties. Available since the 1950s, tetryzoline is a selective α1-receptor agonist that is used as an ocular and nasal decongestant. Tetryzoline is found in a wide array of over-the-counter eye drops, including the most...
Approved
Matched Description: … Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral ... [A231769] Available since the 1950s, tetryzoline is a selective α1-receptor agonist [A231774 ... Tetryzoline is found in a wide array of over-the-counter eye drops, including the most common brand, …
Matched Mixtures name: … ISCHEMOL A ... ISCHEMOL A ... ISCHEMOL A …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Alginic acid

Alginic acid, also referred to as algin or alginate, is a hydrophilic or anionic polysaccharide isolated from certain brown seaweed (Phacophycae) via alkaline extraction. It is present in cell walls of brown algae where it forms a viscous gel when binding with water. Alginic acid is a linear polymer consisted...
Approved
Investigational
Matched Description: … Alginic acid, also referred to as algin or alginate, is a hydrophilic or anionic polysaccharide isolated ... It is present in cell walls of brown algae where it forms a viscous gel when binding with water. ... Alginic acid is a linear polymer consisted of L-glucuronic acid and D-mannuronic acid residues connected …
Matched Mixtures name: … SUSPENSION ORAL CON SABOR A MENTA ... SUSPENSION ORAL CON SABOR A MENTA ... GAVISCON® TABLETAS MASTICABLES SABOR A MENTA …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Ustilago maydis

Ustilago maydis is a fungus which can provoke allergic reactions. Ustilago maydis extract is used in allergenic testing.
Approved
Matched Description: … Ustilago maydis is a fungus which can provoke allergic reactions. …

Blatella germanica

German cockroach allergenic extract is used in allergenic testing.
Approved

Alternaria alternata

Alternaria alternata is a fungus which can provoke allergic reactions. Alternaria alternata extract is used in allergenic testing.
Approved
Matched Description: … Alternaria alternata is a fungus which can provoke allergic reactions. …
Matched Mixtures name: … Mold Mix A ... Mold Mix A …

Sutimlimab

Cold agglutinin disease (CAD) is a type of autoimmune hemolytic anemia (AIHA) in which autoantibodies directed against red blood cell surface antigens cause hemolysis at low (3-4°C) temperatures.[A245154,L40114] This cold subtype accounts for approximately 15-25% of all AIHA and is more common in the elderly.[A245159,L40114] In approximately 90% of cases,...
Approved
Investigational
Matched Description: … Cold agglutinin disease (CAD) is a type of autoimmune hemolytic anemia (AIHA) in which autoantibodies ... [A245144] Hemolysis in patients with CAD is driven by complement activation, which initiates a cascade ... Sutimlimab is a first-in-class humanized monoclonal antibody targeted at complement subunit C1s, which …

Copanlisib

Copanlisib is a selective pan-Class I phosphoinositide 3-kinase (PI3K) inhibitor with preferential activity against the alpha and delta isoforms. PI3K, a lipid kinase that activates downstream signalling pathways involved in cell survival and growth, that exists in different isoforms and is often overexpressed in hematological malignancies. Copanlisib was granted accelerated...
Approved
Investigational
Matched Description: … Copanlisib is a selective pan-Class I phosphoinositide 3-kinase (PI3K) inhibitor with preferential activity ... PI3K, a lipid kinase that activates downstream signalling pathways involved in cell survival and growth …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A7 Substrates with a Narrow Therapeutic Index …

Methocarbamol

Methocarbamol was developed in the early 1950s as a treatment for muscle spasticity and the associated pain.[A178441,A178450] It is a guaiacol glyceryl ether. Methocarbamol tablets and intramuscular injections are prescription medicines indicated in the United States as an adjunct to rest, physical therapy, and other measures for the relief of...
Approved
Vet approved
Matched Description: … [A178441,A178450] It is a guaiacol glyceryl ether. ... Methocarbamol was developed in the early 1950s as a treatment for muscle spasticity and the associated ... [Label,L6268] In Canada, methocarbamol can be sold as an over the counter oral medicine at a lower dose …
Matched Mixtures name: … SINAXAR ® A TABLETAS ... SINAXAR ® A TABLETAS …

Tolcapone

Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). It is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa medication. It is a yellow, odorless, non-hygroscopic, crystalline compound. Tolcapone is associated with a risk of hepatotoxicity.
Approved
Withdrawn
Matched Description: … Tolcapone is associated with a risk of hepatotoxicity. ... It is a yellow, odorless, non-hygroscopic, crystalline compound. ... Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). …

Imipramine

Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, imipramine exerts...
Approved
Matched Description: … In depressed individuals, imipramine exerts a positive effect on mood. ... Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. ... They contain a tricyclic ring system with an alkyl amine substituent on the central ring. …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C18 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …

Propofol

Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness,...
Approved
Investigational
Vet approved
Matched Description: … administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a …

Isoniazid

Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.
Approved
Investigational
Matched Description: … Antibacterial agent used primarily as a tuberculostatic. …

Dimethyl sulfoxide

A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during cryopreservation. Dimethyl sulfoxide shows a range of pharmacological activity including...
Approved
Vet approved
Matched Description: … A highly polar organic liquid, that is used widely as a chemical solvent. ... Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application ... Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Oxyquinoline

Oxyquinoline is a heterocyclic phenol and derivative of quinoline with antiseptic, disinfectant, and pesticide properties. It is used as a stabilizer for hydrogen peroxide, where it is sometimes added in cosmetic products.
Approved
Vet approved
Matched Description: … Oxyquinoline is a heterocyclic phenol and derivative of quinoline with antiseptic, disinfectant, and ... It is used as a stabilizer for hydrogen peroxide, where it is sometimes added in cosmetic products. …
Displaying drugs 201 - 225 of 11524 in total