Displaying drugs 2326 - 2350 of 9732 in total
Amrinone
Amrinone (or inamrinone) is a type 3 pyridine phosphodiesterase inhibitor. It is used in the treatment of congestive heart failure.
Approved
Matched Description: … It is used in the treatment of congestive heart failure. …
Spectinomycin
An antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.
Approved
Investigational
Vet approved
Matched Description: … It is active against gram-negative bacteria and used for the treatment of gonorrhea. …
Lumateperone
Schizophrenia is a complex mental illness and impacts approximately 1% of the population. Although there are several antipsychotics including aripiprazole, paliperidone and clozapine available for clinical use, they are generally accompanied by significant metabolic and/or neurological adverse effects. Lumateperone is a newly approved 2nd generation antipsychotic currently indicated for the...
Approved
Investigational
Matched Description: … Schizophrenia is a complex mental illness and impacts approximately 1% of the population. ... Lumateperone is a newly approved 2nd generation antipsychotic currently indicated for the treatment of ... glutamate, serotonin and dopamine, which are all neurotransmitters that contribute to the pathophysiology of …
Thiohexam
Thiohexam is a rubber cure accelerator. It is also a known allergen and dermatological sensitizer.
Sensitivity to Thiohexam may be identified with a clinical patch test.
Approved
Experimental
Foreskin keratinocyte (neonatal)
Skin, the largest organ of the human body, plays the main role in protecting the body from mechanical damage. It is composed of epidermal, dermal and hypodermal layers. The barrier function of the skin owed to its avascular epidermal layer, which is made mainly of keratinocytes. The keratinocytes form a...
Approved
Matched Description: … rates of wound healing and decreasing the time required for closure of wounds [L2452]. ... The barrier function of the skin owed to its avascular epidermal layer, which is made mainly of keratinocytes ... It is composed of epidermal, dermal and hypodermal layers. …
Stanozolol
Stanozolol is a synthetic anabolic steroid with therapeutic uses in treating hereditary angioedema. Stanozolol is derived from testosterone, and has been abused by several high profile professional athletes.
Approved
Vet approved
Gallium citrate Ga-67
Gallium citrate Ga 67 is the citrate salt of the radioisotope gallium Ga 67. Although the mechanism is unknown, gallium Ga 67 concentrates in lysosomes and is bound to a soluble intracellular protein in certain viable primary and metastatic tumors and focal sites of inflammation, allowing scintigraphic localization. Ga-67 scintigraphy...
Approved
Matched Description: … Gallium citrate Ga 67 is the citrate salt of the radioisotope gallium Ga 67. ... to a soluble intracellular protein in certain viable primary and metastatic tumors and focal sites of …
Isoxsuprine
A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. Its vasodilating actions are greater on the arteries supplying skeletal muscle than on those supplying skin. It is used in the treatment of peripheral vascular disease and in premature labor.
Approved
Withdrawn
Matched Description: … It is used in the treatment of peripheral vascular disease and in premature labor. ... A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. …
Dinoprost tromethamine
The tromethamine (THAM) salt of the naturally occurring prostaglandin F2 alpha, dinoprost tromethamine occurs as a white to off-white, very hygroscopic, crystalline powder. Dinoprost tromethamine may also be known as dinoprost trometamol, PGF2 alpha THAM, or prostaglandin F2 alpha tromethamine.
Approved
Vet approved
Matched Description: … The tromethamine (THAM) salt of the naturally occurring prostaglandin F2 alpha, dinoprost tromethamine …
Tetrachlorodecaoxide
WF10 is a chlorite-based, immunomodulating drug is developed by Nuvo Research Inc. Certain preclinical evidence and clinical pilot data suggest that WF10 may be effective in treating certain cancers. The Corporation believes the research to-date demonstrates that WF10 acts on macrophages (a type of white blood cell) by modulating the...
Approved
Investigational
Matched Description: … in combination with Xeloda (capecitabine) in the treatment of pancreatic cancer. ... The Corporation believes the research to-date demonstrates that WF10 acts on macrophages (a type of white ... The Corporation has commenced a Phase II clinical trial in an effort to demonstrate the efficacy of WF10 …
Selenomethionine
Selenomethionine is a naturally occuring amino acid in some plant materials such as cereal grains, soybeans and enriched yeast but it cannot be synthesized from animals or humans. It can be produced from post-structural modifications. In vivo, selenomethionine plays an essential role in acting as an antioxidant, where it depletes...
Approved
Investigational
Matched Description: … In comparison to selenite, which is the inorganic form of selenium, the organic form of selenomethionine ... antioxidant, where it depletes reactive oxygen species (ROS) and aids in the formation and recycling of ... laboratories where its incorporation into proteins that need to be visualized enhances the performance of …
Light green SF yellowish
Light green SF yellowish is a green triarylmethane dye that is used in the preparation of the staining solution which is widely used as a counterstain. It is used in histological applications and other labratory settings, and usually exists as a disodium salt. The maximum absorption of light green SF...
Approved
Experimental
Matched Description: … the dye and increased tendency of the dye to fade. ... The maximum absorption of light green SF yellowish is at 630 (422) nm. ... Light green SF yellowish is a green triarylmethane dye that is used in the preparation of the staining …
Pegulicianine
Pegulicianine is an optical imaging agent indicated for fluorescence imaging in patients with breast cancer. It is used following surgical resection of the primary tumor to detect areas of remaining cancer. Pegulicianine itself is a prodrug comprising three main fragments, one of which contains a fluorescence quencher that keeps the...
Approved
Matched Description: … It is used following surgical resection of the primary tumor to detect areas of remaining cancer. ... Pegulicianine itself is a prodrug comprising three main fragments, one of which contains a fluorescence ... [L50537] The _in vivo_ enzymatic cleavage of pegulicianine results in two optically active fragments …
Quaternium-15
Quaternium-15 is a quaternary ammonium salt used as a surfactant and preservative in many products including cosmetics. It is an anti-microbial agent by virtue of being a formaldehyde releaser, however this can also cause contact dermatitis, a symptom of an allergic reaction, especially in those with sensitive skin. In 2005,...
Approved
Experimental
Matched Description: … contact dermatitis, a symptom of an allergic reaction, especially in those with sensitive skin. ... It is an anti-microbial agent by virtue of being a formaldehyde releaser, however this can also cause …
Estradiol dienanthate
Estradiol Dienanthate is a pro-drug ester of DB00783, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex hormone. As a pro-drug of estradiol, estradiol benzoate therefore has the same downstream...
Approved
Investigational
Vet approved
Matched Description: … Ester pro-drugs of estradiol are therefore considered to be bioidentical forms of estrogen [T84]. ... Estradiol Dienanthate is a pro-drug ester of [DB00783], a naturally occurring hormone that circulates ... Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex …
Metocurine iodide
Metocurine iodide is a benzylisoquinolinium competitive nondepolarizing neuromuscular blocking agent. It is used as an anesthesia adjunct to induce skeletal muscle relaxation and to reduce the intensity of muscle contractions in convulsive therapy Metocurine iodide has a moderate risk of inducing histamine release and has some ganglion blocking activity. Metocurine...
Approved
Withdrawn
Matched Description: … It is used as an anesthesia adjunct to induce skeletal muscle relaxation and to reduce the intensity of ... muscle contractions in convulsive therapy Metocurine iodide has a moderate risk of inducing histamine ... advantageously if muscle twitch response to peripheral nerve stimulation is monitored to assess degree of …
Cabozantinib
Cabozantinib was first approved in 2012 and is a non-specific tyrosine kinase inhibitor. It was initially approved in the US under the brand name Cometriq, which is indicated for the treatment of metastatic medullary thyroid cancer. In 2016, a capsule formulation (Cabometyx) was approved for the treatment of advanced renal...
Approved
Investigational
Matched Description: … was initially approved in the US under the brand name Cometriq, which is indicated for the treatment of ... [L15123] In 2016, a capsule formulation (Cabometyx) was approved for the treatment of advanced renal ... this same formulation gained additional approval in both the US and Canada in 2019 for the treatment of …
Tripelennamine
A histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. It is used to treat asthma; HAY fever; urticaria; and rhinitis; and also in veterinary applications. Tripelennamine is administered by various routes, including topically.
Approved
Vet approved
Selenic acid
Selenic acid is an organic compound with the chemical formula H2SeO4. It may be found in over-the-counter daily dietary supplements as a source of DB11135, an essential trace mineral for human health.
Approved
Matched Description: … It may be found in over-the-counter daily dietary supplements as a source of [DB11135], an essential …
Levobunolol
A nonselective beta-adrenoceptor antagonist used in the treatment of glaucoma.
Approved
Matched Description: … A nonselective beta-adrenoceptor antagonist used in the treatment of glaucoma. …
2,2'-Dibenzothiazyl disulfide
2,2'-Dibenzothiazyl disulfide is an accelerator used in the processing process for natural and synthetic rubber and plastic regeneration. It is also a known allergen and dermatological sensitizer.
Sensitivity to 2,2'-Dibenzothiazyl disulfide may be identified with a clinical patch test.
Approved
Experimental
Carbamide peroxide
Carbamide peroxide, also known as urea-hydrogen peroxide, is a water-soluble, white crystalline solid compound consisting of hydrogen peroxide and urea. As it is a source of hydrogen peroxide, it can be found in disinfecting and dental bleaching products. Some adverse effects of carbamide peroxide as a dental bleaching agent include...
Approved
Matched Description: … the effectiveness of this ingredient as an oral wound healing agent [L1976]. ... also known as urea-hydrogen peroxide, is a water-soluble, white crystalline solid compound consisting of ... As it is a source of hydrogen peroxide, it can be found in disinfecting and dental bleaching products …
Vibrio cholerae CVD 103-HgR strain live antigen
Vibrio cholerae CVD 103-HgR strain live antigen is a component of Vaxchora, an oral vaccine for immunization against Vibrio cholerae serogroup O1. Cholera is an acute bacterial disease of the small intestine caused by Vibrio cholerae, which is gram-negative bacteria. Two serogroups of V. cholerae, O1 and O139, are causative...
Approved
Investigational
Matched Description: … Two serogroups of _V. cholerae_, O1 and O139, are causative agents of epidemic cholera. ... Serogroup O1 is responsible for the majority of cholera outbreaks. ... _Vibrio cholerae_ CVD 103-HgR strain live antigen is a component of Vaxchora, an oral vaccine for immunization …
Isoetharine
Isoetharine is a relatively selective beta-2 adrenergic agonist. It is a catechol-like agent. Isoetharine is a fast-acting bronchodilator used for emphysema, bronchitis and asthma.
Approved
Antipyrine
An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
Approved
Investigational
Matched Description: … Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes …
Displaying drugs 2326 - 2350 of 9732 in total