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Displaying drugs 1 - 25 of 10494 in total
Yttrium 90 has been investigated for the treatment of Colon Cancer and Colorectal Cancer.
Approved
Investigational
Matched Synonyms: … Yttrium-90 ... Yttrium Y 90 ... Yttrium (90 Y) …
Matched Name: … Yttrium Y-90
Matched Description: … Yttrium 90 has been investigated for the treatment of Colon Cancer and Colorectal Cancer. …
Matched Salts name: … Yttrium-90 chloride ... Yttrium-90 citrate …
Ethotoin is a hydantoin derivative and anticonvulsant. Ethotoin exerts an antiepileptic effect without causing general central nervous system depression. The mechanism of action is probably very similar to that of phenytoin. The latter drug appears to stabilize rather than to raise the normal seizure threshold, and to prevent the spread...
Approved
Matched Synonyms: … 3-ethyl-5-phenyl-2,4-imidazolidinedione ... 3-ethyl-5-phenylimidazolidin-2,4-dione ... 3-Ethyl-5-phenyl-imidazolidine-2,4-dione …
Matched Iupac: … 3-ethyl-5-phenylimidazolidine-2,4-dione …
Diflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic actions similar to other prototypical NSAIAs. Diflunisal possesses anti-inflammatory, analgesic and antipyretic activity. Though its mechanism of action has not been clearly established, most of its actions appear to be associated with inhibition of prostaglandin synthesis via the...
Approved
Investigational
Matched Synonyms: … 2-(hydroxy)-5-(2,4-difluorophenyl)benzoic acid ... 2',4'-difluoro-4-hydroxy-3-biphenylcarboxylic acid ... 5-(2,4-difluorophenyl)salicylic acid …
Matched Iupac: … 2',4'-difluoro-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acid …
Matched Categories: … Non COX-2 selective NSAIDS …
Clobazam belongs to the 1,5-benzodiazepine class of drugs and is marketed under different names, Onfi, Frisium, Urbanyl, and others. . Clobazam was first synthesized in 1966 and first published in 1969, following the incidental synthesis and discovery of the first benzodiazepine chlordiazepoxide in the 1950s. Unlike older 1,4-benzodiazepines, clobazam has...
Approved
Illicit
Matched Synonyms: … 7-Chloro-1-methyl-5-phenyl-1,5-dihydro-benzo[b][1,4]diazepine-2,4-dione ... 1-phenyl-5-methyl-8-chloro-1,2,4,5-tetrahydro-2,4-dioxo-3H-1,5-benzodiazepine …
Matched Iupac: … 7-chloro-1-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine-2,4-dione …
Matched Description: … [A256963,A256868] This is likely because of clobazam's higher affinity to the α2 subunit of …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Dichlorobenzyl alcohol is a mild antiseptic with a broad spectrum for bacterial and virus associated with mouth and throat infections. Dichlorobenzyl alcohol is considered as an active ingredient found in several marketed OTC products by Health Canada which has categorized this agent as an anatomical therapeutic chemical. On the other...
Approved
Matched Synonyms: … 2,4-dichlorobenzenemethanol ... 2,4-dichlorobenzyl alcohol …
Matched Iupac: … (2,4-dichlorophenyl)methanol …
Streptococcus pneumoniae type 5 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 5 individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Synonyms: … Streptococcus pneumoniae serotype 5 capsular antigen diphtheria CRM197 protein conjugate vaccine …
Matched Name: … Streptococcus pneumoniae type 5 capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … Streptococcus pneumoniae type 5 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is ... sterile vaccine that contains saccharides of the capsular antigens of *Streptococcus pneumoniae* serotype 5
A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.
Approved
Investigational
Matched Synonyms: … 2,4-Diamino-6-piperidinopyrimidine 3-oxide ... 6-Piperidin-1-ylpyrimidine-2,4-diamine 3-oxide …
Matched Iupac: … 2,6-diamino-4-(piperidin-1-yl)pyrimidin-1-ium-1-olate …
Matched Salts cas: … 210357-39-4
Matched Mixtures name: … Betamethasone Dipropionate 0.05% / Minoxidil 5% / Niacinamide 2% / Pentoxifylline 0.5% ... MINOXIDIL 7% / NIACINAMIDE 4% s ... Bakumokon 5% Minoxidil …
Matched Products: … ANDROVIUM % 2 TOPIKAL KÖPÜK, 90 GRAM ... ANDROVIUM % 5 TOPIKAL KÖPÜK, 90 GRAM ... PILOGÁN® GEL 2% …
Diaminopyrimidine oxide is a compound similar to minoxidil which is used to aid in hair growth.
Approved
Matched Synonyms: … 2,4-diaminopyrimidine 3-n-oxide ... 2,4-pyrimidinediamine, 3-oxide …
Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections.[L6856,L6859,L6862] Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. This drug is more resistant to the development of bacterial resistance because it acts...
Approved
Vet approved
Matched Synonyms: … 1-((5-nitro-2-furanyl)methylene)amino-2,4-imidazolidenedione ... 5-Nitrofurantoin ... 1-((5-nitrofurfurylidene)amino)hydantoin …
Matched Iupac: … 1-[(E)-[(5-nitrofuran-2-yl)methylidene]amino]imidazolidine-2,4-dione …
Matched Salts cas: … 54-87-5
Matched Products: … PIYELOSEPTYL 25 MG/5 ML ORAL SUSPANSIYON, 100 ML ... PIYELOSEPTYL 25 MG/5 ML ORAL SUSPANSIYON, 200 ML ... PIYELOSEPTYL 25 MG/5 ML ORAL SUSPANSIYON, 300 ML …
Zytron (DMPA) is under investigation for the treatment and health services research of HIV, Lactation, Contraception, Postpartum Depression, and Immune Cells (Mucosal and Systemic). DMPA has been investigated for the prevention, treatment, and basic science of Weight and Microbiota.
Approved
Investigational
Matched Synonyms: … O-(2,4-dichlorophenyl)-O-methyl-isopropylphosphoramidothioate …
Matched Iupac: … [(2,4-dichlorophenoxy)(methoxy)sulfanylidene-lambda5-phosphanyl](propan-2-yl)amine …
Market product is Tc99m-labeled murine antibody fragment for nuclear imaging of activated granulocytes.
Approved
Matched Synonyms: … Immunoglobulin G1 (mouse monoclonal IMMU-MN3 Fab' fragment gamma-chain anti-human NCA-90 granulocyte …
Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the...
Approved
Matched Synonyms: … S)-Isopropyl 2-((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4- dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4 ... -methyltetrahydrofuran-2-yl)methoxy)- (phenoxy)phosphorylamino)propanoate …
Matched Iupac: … propan-2-yl (2S)-2-{[(S)-{[(2R,3R,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-fluoro-3-hydroxy ... -4-methyloxolan-2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate …
Matched Description: … Approved in October 2014 by the FDA, Harvoni is indicated for the treatment of HCV genotypes 1, 4, 5, ... -deoxy-2'-α-fluoro-β-C-methyluridine-5'-triphosphate (also known as GS-461203), which acts as a defective ... a prodrug nucleotide analog, Sofosbuvir is metabolized into its active form as the antiviral agent 2' …
Matched Mixtures name: … HARVONI 90 MG/400 MG FILM KAPLI TABLET, 84 ADET ... HARVONI 90 MG/400 MG FILM KAPLI TABLET, 28 ADET …
A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA...
Approved
Investigational
Vet approved
Matched Synonyms: … 5-ethyl-5-(sec-pentyl)barbituric acid ... 5-ethyl-5-(1-methylbutyl)barbituric acid ... 5-Ethyl-5-(1-methyl-butyl)-pyrimidine-2,4,6-trione …
Matched Iupac: … 5-ethyl-5-(pentan-2-yl)-1,3-diazinane-2,4,6-trione …
Bromothalonil, also known as Methyldibromo glutaronitrile (MDBGN), is a widely used preservative that can be found in many personal hygiene and industrial products. It is also a known allergen and dermatological irritant that has been banned in many EU countries due to increasing rates of contact allergy . In 2005,...
Approved
Experimental
Matched Synonyms: … 1,2-Dibromo-2,4-dicyanobutane ... 2-Bromo-2-(bromomethyl) glutaronitrile ... 2-Bromo-2-(bromomethyl) pentanedinitrile …
Matched Iupac: … 2-bromo-2-(bromomethyl)pentanedinitrile …
A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972) Flavin adenine dinucleotide is approved for use in Japan under the trade name Adeflavin as an ophthalmic treatment for vitamin B2 deficiency.
Approved
Matched Synonyms: … Adenosine 5'-(trihydrogen pyrophosphate), 5'-5'-ester with riboflavine ... Riboflavin 5'-(trihydrogen diphosphate), 5'-5'-ester with adenosine ... adenosine 5'-[3-(riboflavin-5'-yl) dihydrogen diphosphate] …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}[({[(2R,3S,4S)-5-{7,8-dimethyl ... -2,4-dioxo-2H,3H,4H,10H-benzo[g]pteridin-10-yl}-2,3,4-trihydroxypentyl]oxy}(hydroxy)phosphoryl)oxy]phosphinic …
Matched Salts cas: … 84366-81-4
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Tovorafenib is a selective type II RAF kinase inhibitor with anti-tumour activity. It was granted accelerated approval by the FDA, making it the first FDA approval of a systemic therapy for the treatment of pediatric low-grade glioma, with BRAF rearrangements. BRAF oncogenic mutations in cancers drive dysregulated cell growth, proliferation,...
Approved
Investigational
Matched Synonyms: … 4-Pyrimidinecarboxamide, 6-amino-5-chloro-N-[(1R)-1-[5-[[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]amino ... 6-Amino-5-chloro-N-((1R)-1-(5-(((5-chloro-4-(trifluoromethyl)-2-pyridinyl)amino)carbonyl)-2-thiazolyl ... 6-amino-5-chloro-N-[1R)-1-[5-[[[5-hloro-4-(trifluoromethyl)-2pyridinyl]amino]carbonyl]-2-thiazoyl]ethyl …
Matched Iupac: … 6-amino-5-chloro-N-[(1R)-1-(5-{[5-chloro-4-(trifluoromethyl)pyridin-2-yl]carbamoyl}-1,3-thiazol-2-yl) ... ethyl]pyrimidine-4-carboxamide …
A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
Approved
Matched Synonyms: … 5-chloro-2-benzoxazolol ... 5-chloro-2-benzoxazolone ... 5-chloro-2-benzoxazolinone …
Matched Iupac: … 5-chloro-2,3-dihydro-1,3-benzoxazol-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Rosuvastatin, also known as the brand name product Crestor, is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications...
Approved
Matched Synonyms: … (3R,5S,6E)-7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(ethyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5- ... (3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept …
Matched Iupac: … (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept …
Matched Description: … shown that even for low-risk individuals (with <10% risk of a major vascular event occurring within 5 ... cardiovascular events and for people with a moderate to high risk of development of CVD, such as those with Type 2
Matched Salts cas: … 147098-20-2
Matched Mixtures name: … ROVARTALNF-2 ... LODITEN 5/5 MG EFERVESAN TABLET, 90 ADET ... ROSUCOR PLUS 5/5 MG FILM KAPLI TABLET, 90 ADET …
Matched Products: … ULTROX 5 MG FILM TABLET, 90 ADET ... ROSUCOR 5 MG FILM TABLET, 90 ADET ... ROSUSTAR 5 MG FILM TABLET,90 ADET …
Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) indicated for the treatment of HIV infection in adults or combined with tenofovir alafenamide for the prevention of HIV-1 infection in high risk adolescents and adults. Emtricitabine is a cytidine analogue. The drug works by inhibiting HIV reverse transcriptase, preventing transcription of...
Approved
Investigational
Matched Synonyms: … (−)-cis-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one ... (2R-cis)-4-amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone ... 4-amino-5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one …
Matched Iupac: … 5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-4-imino-1,4-dihydropyrimidin-2-ol …
Matched Description: … [L9019] Emtricitabine was granted FDA approval on 2 July 2003.[L9019] …
Matched Mixtures name: … DESCOVY 200 MG/ 10 MG FILM KAPLI TABLET, 90 ADET ... DESCOVY 200 MG/ 25 MG FILM KAPLI TABLET, 90 ADET ... ODEFSEY 200 MG/25 MG/25 MG FİLM KAPLI TABLET, 90 ADET …
Talbutal, also called 5-allyl-5-sec-butylbarbituric acid, is a barbiturate with a short to intermediate duration of action. Talbutal is a schedule III drug in the U.S.
Approved
Illicit
Matched Synonyms: … 5-allyl-5-sec-butylbarbituric acid ... (RS)-5-allyl-5-sec-butylpyrimidine-2,4,6(1H,3H,5H)-trione …
Matched Iupac: … 5-(butan-2-yl)-5-(prop-2-en-1-yl)-1,3-diazinane-2,4,6-trione …
Matched Description: … Talbutal, also called 5-allyl-5-sec-butylbarbituric acid, is a barbiturate with a short to intermediate …
Melatonin is a biogenic amine that is found in animals, plants and microbes. Aaron B. Lerner of Yale University is credited for naming the hormone and for defining its chemical structure in 1958. In mammals, melatonin is produced by the pineal gland. The pineal gland is small endocrine gland, about...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … N-[2-(5-methoxyindol-3-yl)ethyl]acetamide ... 5-methoxy-N-acetyltryptamine ... N-Acetyl-5-methoxytryptamine …
Matched Iupac: … N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Mellozzan 4 mg Tabletten ... Mellozzan 5 mg Tabletten ... Melatonin Rapid Release Gelcaps 5 mg …
A coenzyme for a number of oxidative enzymes including NADH DEHYDROGENASE. It is the principal form in which RIBOFLAVIN is found in cells and tissues.
Approved
Investigational
Matched Synonyms: … riboflavin 5'-phosphate ... Riboflavin-5-phosphate ... riboflavin 5'-monophosphate …
Matched Iupac: … {[(2R,3S,4S)-5-{7,8-dimethyl-2,4-dioxo-2H,3H,4H,10H-benzo[g]pteridin-10-yl}-2,3,4-trihydroxypentyl]oxy …
Matched Salts cas: … 6184-17-4 ... 130-40-5 ... 130-40-5
Matched Mixtures name: … Mvc 9+4 Inj ... B-KOMP ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL, 5 ADET …
Matched Salts name: … Riboflavin 5'-phosphate sodium anhydrous ... Riboflavin-5'-phosphate sodium salt dihydrate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
A barbiturate that is metabolized to phenobarbital. It has been used for similar purposes, especially in epilepsy, but there is no evidence mephobarbital offers any advantage over phenobarbital.
Approved
Matched Synonyms: … 5-ethyl-1-methyl-5-phenylbarbituric acid ... 5-Ethyl-1-methyl-5-phenyl-pyrimidine-2,4,6-trione ... 5-ethyl-1-methyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione …
Matched Iupac: … 5-ethyl-1-methyl-5-phenyl-1,3-diazinane-2,4,6-trione …
Capecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. Capecitabine is a prodrug, that is enzymatically converted to fluorouracil (antimetabolite) in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue.
Approved
Investigational
Matched Synonyms: … pentyl 1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinecarbamate ... Pentyl [1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl]carbamate ... (1-(5-Deoxy-beta-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl)-carbamic acid pentyl ester …
Matched Iupac: … pentyl N-{1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl …
Copanlisib is a selective pan-Class I phosphoinositide 3-kinase (PI3K) inhibitor with preferential activity against the alpha and delta isoforms. PI3K, a lipid kinase that activates downstream signalling pathways involved in cell survival and growth, that exists in different isoforms and is often overexpressed in hematological malignancies. Copanlisib was granted accelerated...
Approved
Investigational
Matched Synonyms: … 2-AMINO-N-(7-METHOXY-8-(3-(MORPHOLIN-4-YL)PROPOXY)-2,3-DIHYDROIMIDAZO(1,2-C)QUINAZOLIN-5-YL(PYRIMIDINE ... 2-AMINO-N-(7-METHOXY-8-(3-MORPHOLIN-4-YLPROPOXY)-2,3-DIHYDROIMIDAZO(1,2-C)QUINAZOLIN-5-YL)PYRIMIDINE- ... 5-PYRIMIDINECARBOXAMIDE, 2-AMINO-N-(2,3-DIHYDRO-7-METHOXY-8-(3-(4-MORPHOLINYL)PROPOXY)IMIDAZO(1,2-C)QUINAZOLIN …
Matched Iupac: … 2-amino-N-{7-methoxy-8-[3-(morpholin-4-yl)propoxy]-2H,3H-imidazo[1,2-c]quinazolin-5-yl}pyrimidine-5-carboxamide …
Matched Categories: … MATE 2 Inhibitors ... Heterocyclic Compounds, 2-Ring …
Displaying drugs 1 - 25 of 10494 in total