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Displaying drugs 1 - 25 of 4858 in total

Brilliant blue G

Brilliant Blue G is used in an ophthalmic solution for staining the internal limiting membrane (ILM) of the eye during ophthalmic procedures.[A188841,A188844] This membrane is thin and translucent, making it difficult to identify during eye surgeries that require high levels of visual accuracy. Brilliant blue G, like its name, imparts...
Approved
Matched Synonyms: … Acid Blue 90 ... Acid Blue 90 …

Influenza B virus B/Texas/6/2011 antigen (formaldehyde inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza B virus B/Texas/6/2011 antigen (formaldehyde inactivated) …

Influenza A virus A/Darwin/6/2021 (H3N2) recombinant hemagglutinin antigen

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza A virus A/Darwin/6/2021 (H3N2) recombinant hemagglutinin antigen …

Metacycline

A broad-spectrum semisynthetic antibiotic related to tetracycline but excreted more slowly and maintaining effective blood levels for a more extended period.
Approved
Investigational
Matched Synonyms: … 6-Demethyl-6-deoxy-5-hydroxy-6-methylenetetracycline ... 6-Deoxy-6-demethyl-6-methylene-5-oxytetracycline ... 6-Methyleneoxytetracycline …
Matched Iupac: … (4S,4aR,5S,5aR,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methylidene-1,11-dioxo-1,4,4a,5,5a …

Mercaptopurine

An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.
Approved
Matched Synonyms: … 6 MP ... 6-MP ... 6-Thioxopurine …
Matched Iupac: … 6,7-dihydro-3H-purine-6-thione …

Megestrol acetate

17-Hydroxy-6-methylpregna-3,6-diene-3,20-dione. A progestational hormone used most commonly as the acetate ester. As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative treatment of breast cancer.
Approved
Investigational
Vet approved
Matched Synonyms: … 17α-Acetoxy-6-dehydro-6-methylprogesterone ... 17alpha-Acetoxy-6-dehydro-6-methylprogesterone ... 6-Dehydro-6-methyl-17α-acetoxyprogesterone …
Matched Description: … 17-Hydroxy-6-methylpregna-3,6-diene-3,20-dione. …

Tioguanine

An antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.
Approved
Matched Synonyms: … 6-TG ... 6-Thioguanine ... 6-Mercaptoguanine …
Matched Iupac: … 2-amino-6,7-dihydro-3H-purine-6-thione …

Influenza A virus A/Darwin/6/2021 IVR-227 (H3N2) antigen (propiolactone inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza A virus A/Darwin/6/2021 IVR-227 (H3N2) antigen (propiolactone inactivated) …

Etoricoxib

Etoricoxib is a new COX-2 selective inhibitor. Current therapeutic indications are: treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. Like any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic...
Approved
Investigational
Matched Synonyms: … 5-Chloro-3-(4-methanesulfonyl-phenyl)-6'-methyl-[2,3']bipyridinyl ... 5-chloro-6'-methyl-3-(p-(methylsulfonyl)phenyl)-2,3'-bipyridine ... 5-chloro-2-(6-methylpyridin-3-yl)-3-(4-(methylsulfonyl)phenyl)pyridine …
Matched Iupac: … 5-chloro-3-(4-methanesulfonylphenyl)-6'-methyl-2,3'-bipyridine …
Matched Products: … ETROBAX 90 FILM COATED TABLETS 90 MG ... LACOSIB 90 ... COXIRON 90 …

Pyrimethamine

One of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis.
Approved
Investigational
Vet approved
Matched Synonyms: … 2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine ... 2,4-Diamino-5-chlorophenyl-6-ethylpyrimidine ... 2,4-Diamino-5-(P-chlorophenyl)-6-ethylpyrimidine …
Matched Iupac: … 5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine …

Hydromorphone

Hydromorphone is a pure opioid, a semi-synthetic hydrogenated ketone derivative of morphine that has been available clinically since 1920. Structurally, hydromorphone derived from morphine in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and...
Approved
Illicit
Matched Synonyms: … 6-Deoxy-7,8-dihydro-6-oxomorphine ... 4,5-Epoxy-3-hydroxy-17-methylmorphinan-6-one ... (-)-(5R)-4,5-Epoxy-3-hydroxy-9α-methylmorphinan-6-one …
Matched Description: … [A176471] Even though hydromorphone does not present a 6-hydroxyl group, it is categorized under the ... Structurally, hydromorphone derived from [morphine] in the modification of the hydroxyl group in the carbon 6 …

Idebenone

Idebenone is a synthetic analogue of ubiquinone (also known as Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC). It has been proposed that by interacting with the ETC, idebenone increases ATP production required for mitochondrial function, reduces free radicals, inhibits lipid peroxidation, and...
Approved
Investigational
Matched Synonyms: … 6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-p-benzoquinone ... 6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone ... 2,3-dimethoxy-5-methyl-6-(10'-hydroxydecyl)-1,4-benzoquinone …
Matched Mixtures name: … EVERON 90/5 MG FILM KAPLI TABLET ,50 TABLET ... EVERON 90/5 MG FILM KAPLI TABLET ,100 TABLET ... SALPEZIL 90/10 MG FILM KAPLI TABLET ,TABLET, 28 ADET …
Matched Products: … IDEBEX 90 MG FILM KAPLI TABLET ,90 FILM KAPLI TABLET ... IDEBEX 45 MG FILM KAPLI TABLET ,90 FILM KAPLI TABLET ... IDEBEX 90 MG FILM KAPLI TABLET ,FILM KAPLI TABLET, 30 ADET …

Adenine

A purine base and a fundamental unit of adenine nucleotides.
Approved
Nutraceutical
Matched Synonyms: … 6-Aminopurine …
Matched Iupac: … 7H-purin-6-amine …

Olutasidenib

Olutasidenib (FT-2102) is a selective and potent isocitrate dehydrogenase-1 (IDH1) inhibitor approved by the FDA in December 2022.[L44256,L44261] It is indicated for the treatment of relapsed or refractory acute myeloid leukemia (AML) in patients with a susceptible IDH1 mutation as determined by an FDA-approved test. IDH1 mutations are common in...
Approved
Investigational
Matched Synonyms: … 1-methyl-6-oxo- ... (s)-5-((1-(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl)amino)-1-methyl-6-oxo-1,6-dihydropyridine-2- ... 5-(((1s)-1-(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl)amino)-1-methyl-6-oxo-1,6-dihydropyridine-2 …
Matched Iupac: … 5-{[(1S)-1-(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl]amino}-1-methyl-6-oxo-1,6-dihydropyridine-2 …

Elosulfase alfa

Elosulfase alfa is a synthetic version of the enzyme N-acetylgalactosamine-6-sulfatase. It was approved by the FDA in 2014 for the treatment of Morquio syndrome. Elosulfase alfa was developed by BioMarin Pharmaceutical Inc. and is marketed under the brand Vimizim™. The recommended dose is 2 mg per kg given intravenously over...
Approved
Investigational
Matched Synonyms: … Recombinant human N-acetylgalactosamine-6-sulfatase ... Recombinant human N-acetylgalactosamine-6-sulfatase (rhGALNS) …
Matched Description: … Elosulfase alfa is a synthetic version of the enzyme N-acetylgalactosamine-6-sulfatase. …

Dydrogesterone

A synthetic progestational hormone with no androgenic or estrogenic properties. Unlike many other progestational compounds, dydrogesterone produces no increase in temperature and does not inhibit ovulation.
Approved
Investigational
Withdrawn
Matched Synonyms: … delta(6)-Retroprogesterone ... 6-Dehydro-retro-progesterone ... Retro-6-dehydroprogesterone …

Nelarabine

Nelarabine is an antineoplastic agent that is typically used to treat acute T-cell lymphoblastic leukemia, particularly T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL), in both adult and pediatric patients whose disease has not responded to or has relapsed following at least two chemotherapy regimens. T-cell acute lymphoblastic...
Approved
Investigational
Matched Synonyms: … 2-Amino-9-beta-D-arabinofuranosyl-6-methoxy-9H-purine …
Matched Iupac: … (2R,3S,4S,5R)-2-(2-amino-6-methoxy-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol …
Matched Products: … NELARAMAX 250 MG/50 ML IV İNFÜZYONLUK ÇÖZELTİ , 6 ADET …

Azathioprine

Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic index.[A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and as an immunosuppressant in the prevention of...
Approved
Matched Synonyms: … 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine ... 6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine …
Matched Iupac: … 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine …
Matched Description: … Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange ... , and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic …

Enoxacin

A broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.
Approved
Investigational
Matched Synonyms: … 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid ... 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid …
Matched Iupac: … 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid …
Matched Description: … A broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related …
Matched Products: … REKSOTİN 200 MG FİLM TABLET, 6 TABLET …

Levobupivacaine

Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by AstraZeneca under the trade name Chirocaine. In particular, the specific levobupivacaine enantiomer is a worthwhile pursuit because it demonstrates less vasodilation and possesses a...
Approved
Investigational
Matched Synonyms: … (S)-1-butyl-2',6'-pipecoloxylidide ... L-(-)-1-Butyl-2',6'-pipecoloxylidide …

Dapagliflozin

Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor to be approved. indicated for managing diabetes mellitus type 2. When combined with diet and exercise in adults, dapagliflozin helps to improve glycemic control by inhibiting glucose reabsorption in the proximal tubule of the nephron...
Approved
Matched Synonyms: … (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6- (hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol …
Matched Iupac: … (2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl}-6-(hydroxymethyl)oxane-3,4,5-triol …
Matched Products: … DAPAGLEZE 10 MG FILM KAPLI TABLET, 90 ADET ... DAPAGLEZE 5 MG FILM KAPLI TABLET, 90 ADET ... CALİRA 10 MG FİLM KAPLI TABLET, 90 ADET …

Amiloride

A pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with...
Approved
Matched Synonyms: … N-amidino-3,5-diamino-6-chloropyrazinecarboxamide ... 3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide …
Matched Iupac: … 3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide …

Cabergoline

Cabergoline, an ergot derivative, is a long-acting dopamine agonist and prolactin inhibitor. It is used to treat hyperprolactinemic disorders and Parkinsonian Syndrome. Cabergoline possesses potent agonist activity on dopamine D2 receptors.
Approved
Matched Synonyms: … (8R)-6-allyl-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)ergoline-8-carboxamide ... 1-((6-allylergolin-8β-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea ... 1-ethyl-3-(3'-dimethylamionpropyl)-2-(6'-allylergoline-8'β-carbonyl)urea …
Matched Iupac: … 1-[3-(dimethylamino)propyl]-3-ethyl-1-[(2R,4R,7R)-6-(prop-2-en-1-yl)-6,11-diazatetracyclo[7.6.1.0^{2,7 …

Dorzolamide

Dorzolamide is a non-bacteriostatic sulfonamide derivative and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and ocular hypertension. It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. Unlike oral CA inhibitors, dorzolamide...
Approved
Matched Synonyms: … (4S,6S)-4-ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic ... 4-Ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic acid ... (4S,trans)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide …
Matched Iupac: … (2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H-1lambda6-thieno[2,3-b]thiopyran-6-sulfonamide …
Matched Mixtures name: … TOMEC %2 + %0.5 STERIL OFTALMIK ÇÖZELTİ, 6 ML …

Benzthiazide

Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat...
Approved
Matched Synonyms: … 3-benzylthiomethyl-6-chloro-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide ... 3-((benzylthio)methyl)-6-chloro-7-sulfamoyl-2H-benzo-1,2,4-thiadiazine 1,1-dioxide ... 3-benzylthiomethyl-6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide …
Matched Iupac: … 3-[(benzylsulfanyl)methyl]-6-chloro-1,1-dioxo-4H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Displaying drugs 1 - 25 of 4858 in total