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Displaying drugs 1 - 25 of 5555 in total
Vinflunine
Vinflunine is a third-generation member of the vinca alkaloid family with anti-tumour actions. It was first described in 1998 at the Pierre Fabre research center in France. Like other vinca agents, vinflunine is an anti-mitotic agent that induces a cell cycle arrest at the G2/M phase and promotes cell death...
Approved
Investigational
Matched Synonyms: … 20',20'-difluoro-3',4'-dihydrovinorelbine ... 4'-deoxy-20',20'-difluoro-5'-norvincaleukoblastine ... 4'-deoxy-20',20'-difluoro-8'-norvincaleukoblastine …
Naloxegol
Naloxegol, for "PEGylated naloxol" is a peripherally-selective opioid antagonist developed by AstraZeneca. It was approved by the FDA in September 2014 and is indicated for the treatment of opioid-induced constipation (OIC) in adult patients with chronic non‑cancer pain. The advantage of naloxegol over the opioid antagonist naloxone is that its...
Approved
Matched Synonyms: … (5α,6α)-17-Allyl-6-[(20-hydroxy-3,6,9,12,15,18-hexaoxaicos-1-yl)oxy]-4,5-epoxymorphinan-3,14-diol …
Unoprostone
Unoprostone isopropyl is a prostaglandin analogue. Ophthalmic Solution 0.15% is a synthetic docosanoid. Unoprostone isopropyl has the chemical name isopropyl (+)-(Z)-7-[(1R,2R,3R,5S)-3,5 dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoate.
The main indication of Unoprostane is treatment of glucoma.
Approved
Investigational
Matched Synonyms: … 13,14-dihydro-15-keto-20-ethyl PGF2α …
Brexanolone
As of March 2019, brexanolone - developed and made available commercially by Sage Therapeutics Inc. as the brand name product Zulresso - is the first drug to have ever been approved by the US FDA specifically for the treatment of postpartum depression (PPD) in adult females . Since PPD, like...
Approved
Investigational
Matched Synonyms: … allopregnan-3α-ol-20-one …
Influenza B virus B/Texas/6/2011 antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza B virus B/Texas/6/2011 antigen (formaldehyde inactivated) …
Influenza A virus A/Darwin/6/2021 (H3N2) recombinant hemagglutinin antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza A virus A/Darwin/6/2021 (H3N2) recombinant hemagglutinin antigen …
Desogestrel
Desogestrel, a prodrug, is a third generation progestogen and hence, a member of the gonane family which was largely used in Europe before being approved in the US and Canada. It was firstly generated from a study that showed that 11-beta and 11-alkylidene substituent in nortestosterone can enhance the biological...
Approved
Matched Synonyms: … 13-Ethyl-11-methylene-18,19-dinor-17α-pregn-4-en-20-yn-17-ol …
Matched Mixtures name: … Desofemine 20 Mikrogramm/150 Mikrogramm Filmtabletten ... Desogestrel/Ethinylestradiol Effik 150 Mikrogramm/20 Mikrogramm Tabletten …
Matched Mixtures name: … Desofemine 20 Mikrogramm/150 Mikrogramm Filmtabletten ... Desogestrel/Ethinylestradiol Effik 150 Mikrogramm/20 Mikrogramm Tabletten …
Tibolone
Tibolone is a synthetic steroid hormone drug, which is mainly non-selective in its binding profile, acting as an agonist primarily at estrogen receptors (ER), with a preference for ER alpha .
Tibolone (Livial, Org OD 14), produced by Organon (West Orange, NJ), is a synthetic steroid that possesses estrogenic, androgenic...
Approved
Investigational
Matched Synonyms: … 17-hydroxy-7alpha-methyl-19-nor-17alpha-pregn-5(10)-en-20-yn-3-one …
Megestrol acetate
17-Hydroxy-6-methylpregna-3,6-diene-3,20-dione. A progestational hormone used most commonly as the acetate ester. As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative treatment of breast cancer.
Approved
Investigational
Vet approved
Matched Synonyms: … 17α-Acetoxy-6-dehydro-6-methylprogesterone ... 17alpha-Acetoxy-6-dehydro-6-methylprogesterone ... 6-Dehydro-6-methyl-17α-acetoxyprogesterone …
Matched Description: … 17-Hydroxy-6-methylpregna-3,6-diene-3,20-dione. …
Matched Description: … 17-Hydroxy-6-methylpregna-3,6-diene-3,20-dione. …
Mercaptopurine
An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.
Approved
Matched Synonyms: … 6 MP ... 6-MP ... 6-Thioxopurine …
Matched Iupac: … 6,7-dihydro-3H-purine-6-thione …
Matched Iupac: … 6,7-dihydro-3H-purine-6-thione …
Metacycline
A broad-spectrum semisynthetic antibiotic related to tetracycline but excreted more slowly and maintaining effective blood levels for a more extended period.
Approved
Investigational
Matched Synonyms: … 6-Demethyl-6-deoxy-5-hydroxy-6-methylenetetracycline ... 6-Deoxy-6-demethyl-6-methylene-5-oxytetracycline ... 6-Methyleneoxytetracycline …
Matched Iupac: … (4S,4aR,5S,5aR,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methylidene-1,11-dioxo-1,4,4a,5,5a …
Matched Iupac: … (4S,4aR,5S,5aR,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methylidene-1,11-dioxo-1,4,4a,5,5a …
Hydromorphone
Hydromorphone is a pure opioid, a semi-synthetic hydrogenated ketone derivative of morphine that has been available clinically since 1920. Structurally, hydromorphone derived from morphine in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and...
Approved
Illicit
Matched Synonyms: … 6-Deoxy-7,8-dihydro-6-oxomorphine ... 4,5-Epoxy-3-hydroxy-17-methylmorphinan-6-one ... (-)-(5R)-4,5-Epoxy-3-hydroxy-9α-methylmorphinan-6-one …
Matched Description: … [A176471] Even though hydromorphone does not present a 6-hydroxyl group, it is categorized under the ... Structurally, hydromorphone derived from [morphine] in the modification of the hydroxyl group in the carbon 6 …
Matched Products: … Hydromorphone Hp 20 ... Hydal 20 mg/ml Injektions-/Infusionslösung ... Hydagelan 20 mg/ml Injektions-/Infusionslösung …
Matched Description: … [A176471] Even though hydromorphone does not present a 6-hydroxyl group, it is categorized under the ... Structurally, hydromorphone derived from [morphine] in the modification of the hydroxyl group in the carbon 6 …
Matched Products: … Hydromorphone Hp 20 ... Hydal 20 mg/ml Injektions-/Infusionslösung ... Hydagelan 20 mg/ml Injektions-/Infusionslösung …
Influenza A virus A/Darwin/6/2021 IVR-227 (H3N2) antigen (propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza A virus A/Darwin/6/2021 IVR-227 (H3N2) antigen (propiolactone inactivated) …
Tioguanine
An antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.
Approved
Matched Synonyms: … 6-TG ... 6-Thioguanine ... 6-Mercaptoguanine …
Matched Iupac: … 2-amino-6,7-dihydro-3H-purine-6-thione …
Matched Iupac: … 2-amino-6,7-dihydro-3H-purine-6-thione …
Dydrogesterone
A synthetic progestational hormone with no androgenic or estrogenic properties. Unlike many other progestational compounds, dydrogesterone produces no increase in temperature and does not inhibit ovulation.
Approved
Investigational
Withdrawn
Matched Synonyms: … delta(6)-Retroprogesterone ... 6-Dehydro-retro-progesterone ... Retro-6-dehydroprogesterone …
Matched Products: … DUPHASTON 10 MG FİLM KAPLI TABLET, 20 ADET …
Matched Products: … DUPHASTON 10 MG FİLM KAPLI TABLET, 20 ADET …
Ouabain
A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like digitalis. It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-exchanging ATPase.
Approved
Matched Synonyms: … 3-(α-L-rhamnopyranosyloxy)-1β,5β,11α,14,19-pentahydroxy-5β-card-20(22)-enolide …
Matched Iupac: … 10R,11aR)-3a,5a,9,10-tetrahydroxy-9a-(hydroxymethyl)-11a-methyl-7-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6- …
Matched Iupac: … 10R,11aR)-3a,5a,9,10-tetrahydroxy-9a-(hydroxymethyl)-11a-methyl-7-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6- …
Dorzolamide
Dorzolamide is a non-bacteriostatic sulfonamide derivative and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and ocular hypertension. It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. Unlike oral CA inhibitors, dorzolamide...
Approved
Matched Synonyms: … (4S,6S)-4-ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic ... 4-Ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic acid ... (4S,trans)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide …
Matched Iupac: … (2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H-1lambda6-thieno[2,3-b]thiopyran-6-sulfonamide …
Matched Mixtures name: … TOMEC %2 + %0.5 STERIL OFTALMIK ÇÖZELTİ, 6 ML ... COSOPT S 20/5MG/ML ... DORZOCOMP VISI 20+5MG/ML …
Matched Products: … TRUSOPT 20 MG/ML ... DORZOLAMID AL 20 MG/ML ... Vizidor 20 mg/ml Augentropfen …
Matched Iupac: … (2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H-1lambda6-thieno[2,3-b]thiopyran-6-sulfonamide …
Matched Mixtures name: … TOMEC %2 + %0.5 STERIL OFTALMIK ÇÖZELTİ, 6 ML ... COSOPT S 20/5MG/ML ... DORZOCOMP VISI 20+5MG/ML …
Matched Products: … TRUSOPT 20 MG/ML ... DORZOLAMID AL 20 MG/ML ... Vizidor 20 mg/ml Augentropfen …
Pyrimethamine
One of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis.
Approved
Investigational
Vet approved
Matched Synonyms: … 2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine ... 2,4-Diamino-5-chlorophenyl-6-ethylpyrimidine ... 2,4-Diamino-5-(P-chlorophenyl)-6-ethylpyrimidine …
Matched Iupac: … 5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine …
Matched Iupac: … 5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine …
Azathioprine
Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic index.[A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and as an immunosuppressant in the prevention of...
Approved
Matched Synonyms: … 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine ... 6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine …
Matched Iupac: … 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine …
Matched Description: … [L11214] Azathiprine was granted FDA approval on 20 March 1968.[L11214] ... Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange ... , and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic …
Matched Iupac: … 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine …
Matched Description: … [L11214] Azathiprine was granted FDA approval on 20 March 1968.[L11214] ... Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange ... , and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic …
Nomegestrol acetate
Nomegestrol acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone therapy, and for the treatment of gynecological disorders.
Approved
Investigational
Matched Synonyms: … 17-alpha-Acetoxy-6-methyl-19-nor-4,6-pregnadiene-3,20-dione ... 17-alpha-Hydroxy-6-methyl-19-norpregna-4,6-diene-3,20-dione acetate …
Amiloride
A pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with...
Approved
Matched Synonyms: … N-amidino-3,5-diamino-6-chloropyrazinecarboxamide ... 3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide …
Matched Iupac: … 3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide …
Matched Products: … KALURID TABLET, 20 ADET ... AMILORID TABLET, 20 ADET …
Matched Iupac: … 3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide …
Matched Products: … KALURID TABLET, 20 ADET ... AMILORID TABLET, 20 ADET …
Adenine
A purine base and a fundamental unit of adenine nucleotides.
Approved
Nutraceutical
Matched Synonyms: … 6-Aminopurine …
Matched Iupac: … 7H-purin-6-amine …
Matched Iupac: … 7H-purin-6-amine …
Cabergoline
Cabergoline, an ergot derivative, is a long-acting dopamine agonist and prolactin inhibitor. It is used to treat hyperprolactinemic disorders and Parkinsonian Syndrome. Cabergoline possesses potent agonist activity on dopamine D2 receptors.
Approved
Matched Synonyms: … (8R)-6-allyl-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)ergoline-8-carboxamide ... 1-((6-allylergolin-8β-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea ... 1-ethyl-3-(3'-dimethylamionpropyl)-2-(6'-allylergoline-8'β-carbonyl)urea …
Matched Iupac: … 1-[3-(dimethylamino)propyl]-3-ethyl-1-[(2R,4R,7R)-6-(prop-2-en-1-yl)-6,11-diazatetracyclo[7.6.1.0^{2,7 …
Matched Products: … CABASER 1 MG TABLET, 20 ADET ... CABASER 2 MG TABLET, 20 ADET …
Matched Iupac: … 1-[3-(dimethylamino)propyl]-3-ethyl-1-[(2R,4R,7R)-6-(prop-2-en-1-yl)-6,11-diazatetracyclo[7.6.1.0^{2,7 …
Matched Products: … CABASER 1 MG TABLET, 20 ADET ... CABASER 2 MG TABLET, 20 ADET …
Cabazitaxel
Cabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree. As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and induces tumour cell death. Due to its low affinity for the P-glycoprotein (P-gp) efflux pump, cabazitaxel can more readily penetrate the blood–brain barrier compared to...
Approved
Matched Synonyms: … .,20-EPOXYTAX-11-ENE-2.ALPHA.,4,13.ALPHA. …
Matched Iupac: … carbonyl]amino}-2-hydroxy-3-phenylpropanoyl]oxy}-1-hydroxy-9,12-dimethoxy-10,14,17,17-tetramethyl-11-oxo-6- …
Matched Products: … Cabazitaxel G.L. 20 mg/ml-Konzentrat zur Herstellung einer Infusionslösung ... Cabazitaxel STADA 20 mg/ml Konzentrat zur Herstellung einer Infusionslösung ... Cabazitaxel Viatris 20 mg/ml Konzentrat zur Herstellung einer Infusionslösung …
Matched Iupac: … carbonyl]amino}-2-hydroxy-3-phenylpropanoyl]oxy}-1-hydroxy-9,12-dimethoxy-10,14,17,17-tetramethyl-11-oxo-6- …
Matched Products: … Cabazitaxel G.L. 20 mg/ml-Konzentrat zur Herstellung einer Infusionslösung ... Cabazitaxel STADA 20 mg/ml Konzentrat zur Herstellung einer Infusionslösung ... Cabazitaxel Viatris 20 mg/ml Konzentrat zur Herstellung einer Infusionslösung …
Elosulfase alfa
Elosulfase alfa is a synthetic version of the enzyme N-acetylgalactosamine-6-sulfatase. It was approved by the FDA in 2014 for the treatment of Morquio syndrome. Elosulfase alfa was developed by BioMarin Pharmaceutical Inc. and is marketed under the brand Vimizim™. The recommended dose is 2 mg per kg given intravenously over...
Approved
Investigational
Matched Synonyms: … Recombinant human N-acetylgalactosamine-6-sulfatase ... Recombinant human N-acetylgalactosamine-6-sulfatase (rhGALNS) …
Matched Description: … Elosulfase alfa is a synthetic version of the enzyme N-acetylgalactosamine-6-sulfatase. …
Matched Description: … Elosulfase alfa is a synthetic version of the enzyme N-acetylgalactosamine-6-sulfatase. …
Displaying drugs 1 - 25 of 5555 in total