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Displaying drugs 1 - 25 of 7273 in total

p-Phenylenediamine

Approved
Experimental
Matched Synonyms: … p-Diaminobenzene …
Matched Name: … p-Phenylenediamine …
Matched Salts name: … p-Phenylenediamine dihydrochloride …

P-nitrobiphenyl

Pnb has been used in trials studying the treatment of Pelvic Organ Prolapse.
Approved
Experimental
Investigational
Matched Name: … P-nitrobiphenyl …

Methylparaben

Methylparaben is used in allergenic testing.
Approved
Matched Synonyms: … methyl p-hydroxybenzoate ... p-Methoxycarbonylphenol ... p-Oxybenzoesauremethylester …

Dofetilide

Dofetilide is a class III antiarrhythmic agent that is approved by the Food and Drug Administration (FDA) for the maintenance of sinus rhythm in individuals prone to the formation of atrial fibrillation and flutter, and for the chemical cardioversion to sinus rhythm from atrial fibrillation and flutter.
Approved
Investigational
Matched Synonyms: … beta-((p-Methanesulfonamidophenethyl)methylamino)methanesulfono-p-phenetidide …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …

Chlorphenesin

Approved
Experimental
Matched Synonyms: … glycerol α-p-chlorophenyl ether ... 3-(p-chlorophenoxy)-1,2-propanediol ... p-chlorophenyl-α-glyceryl ether …
Matched Categories: … Cytochrome P-450 CYP3A Inducers ... Cytochrome P-450 CYP3A4 Inducers ... Cytochrome P-450 Enzyme Inducers ... Cytochrome P-450 CYP3A4 Inducers (strength unknown) …

Procainamide

A derivative of procaine with less CNS action.
Approved
Matched Synonyms: … p-Aminobenzoic diethylaminoethylamide ... p-Amino-N-(2-diethylaminoethyl)benzamide …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2D6 Substrates ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …

Bezafibrate

Antilipemic agent that lowers cholesterol and triglycerides. It decreases low density lipoproteins and increases high density lipoproteins.
Approved
Investigational
Matched Synonyms: … 2-(p-(2-(p-Chlorobenzamido)ethyl)phenoxy)-2-methylpropionic acid …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C8 Inhibitors ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates ... Cytochrome P-450 Enzyme Inhibitors …

Tolazamide

A sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide.
Approved
Investigational
Matched Synonyms: … 1-(Hexahydro-1-azepinyl)-3-p-tolylsulfonylurea ... N-(p-Toluenesulfonyl)-N'-hexamethyleniminourea ... 4-(p-Tolylsulfonyl)-1,1-hexamethylenesemicarbazide …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates …

Dapsone

A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae. Its mechanism of action is probably similar to that of the sulfonamides which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with pyrimethamine in the treatment of...
Approved
Investigational
Matched Synonyms: … p,p-sulphonylbisbenzamine ... p,p-sulphonylbisbenzenamine ... p,p'-diaminodiphenyl sulfone …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Inducers ... Cytochrome P-450 CYP2C8 Substrates ... Cytochrome P-450 Enzyme Inducers ... Cytochrome P-450 CYP2C18 Substrates …

Chlorpropamide

Chlorpropamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. Medications in this class...
Approved
Investigational
Matched Synonyms: … 1-(p-chlorobenzenesulfonyl)-3-propylurea ... 1-(p-chlorophenylsulfonyl)-3-propylurea ... 1-propyl-3-(p-chlorobenzenesulfonyl)urea …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates ... Cytochrome P-450 CYP2C19 Substrates …

Tolbutamide

Tolbutamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It is structurally similar to acetohexamide, chlorpropamide and tolazamide and belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin...
Approved
Investigational
Matched Synonyms: … 1-Butyl-3-(p-tolylsulfonyl)urea ... 1-p-Toluenesulfonyl-3-butylurea ... 1-Butyl-3-(p-methylphenylsulfonyl)urea …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C18 Substrates ... Cytochrome P-450 CYP2C8 Inhibitors ... Cytochrome P-450 CYP2C19 Substrates ... Cytochrome P-450 CYP2C8 Substrates …

Chlorambucil

A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Approved
Matched Synonyms: … 4-(p-bis(beta-chloroethyl)aminophenyl)butyric acid ... 4-(p-bis(β-chloroethyl)aminophenyl)butyric acid ... 4-[p-[bis(2-chloroethyl)amino]phenyl]butyric acid …

Hydroxyamphetamine

Hydroxyamphetamine is a derivative of amphetamines. Hydroxyamphetamine is intended mainly as local eye drops for diagnostic purposes. It is indirect sympathomimetic agent which cause dilation of the eye pupil before diagnostic test. Among the minor side effects from its use are: change in color vision, difficulty seeing at night, dry...
Approved
Matched Synonyms: … p-hydroxyamphetamine ... dl-p-hydroxyamphetamine …

Amiloxate

Amiloxate is an EMA-approved chemical UV-filter found in over-the-counter sunscreen products at concentrations up to 10%m . It is often referred to as isoamyl 4-methoxycinnamate or isoamyl p-methoxycinnamate. Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity .
Approved
Matched Synonyms: … Isoamyl p-methoxycinnamate ... Isoamyl-p-methoxycinnamate …
Matched Description: … It is often referred to as isoamyl 4-methoxycinnamate or isoamyl p-methoxycinnamate. …

Chlorphenesin carbamate

Approved
Vet approved
Withdrawn
Matched Synonyms: … 1,2-propanediol-3-(p-chlorophenoxy)-1-carbamate ... 3-(p-chlorophenoxy)-2-hydroxypropyl carbamate ... 3-(p-chlorophenoxy)-1,2-propanediol 1-carbamate …

Melphalan

Melphalan is a nitrogen mustard or bischloroethylamine type alkylating agent. It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard.[A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. It is also used for high-conditioning before hematopoietic stem...
Approved
Matched Synonyms: … p-L-Sarcolysin ... 3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine ... 3-p-(Di(2-chloroethyl)amino)-phenyl-L-alanine …

Tetracaine

Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.
Approved
Vet approved
Matched Synonyms: … 2-(Dimethylamino)ethyl p-(butylamino)benzoate ... p-Butylaminobenzoyl-2-dimethylaminoethanol ... Diäthylaminoäthanol ester der p-butylaminobenzösäure …

Cinoxate

Approved
Matched Synonyms: … 2-Ethoxyethyl-p-methoxycinnamate …

Haloperidol

Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently used antipsychotic medications used worldwide. While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain, it exerts its antipsychotic effect through its strong antagonism of the dopamine receptor (mainly D2), particularly within...
Approved
Matched Synonyms: … 1-(3-p-fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine ... γ-(4-(p-chlorophenyl)-4-hydroxpiperidino)-p-fluorbutyrophenone ... 4'-fluoro-4-(4-(p-chlorophenyl)-4-hydroxypiperidinyl)butyrophenone …
Matched Categories: … P-glycoprotein inhibitors ... P-glycoprotein substrates ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates ... Cytochrome P-450 CYP2C9 Substrates …

Procarbazine

An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
Approved
Investigational
Matched Synonyms: … 1-Methyl-2-(p-(isopropylcarbamoyl)benzyl)hydrazine ... 2-(p-Isopropylcarbamoylbenzyl)-1-methylhydrazine ... N-Isopropyl-α-(2-methylhydrazino)-p-toluamide …

Acetohexamide

A sulfonylurea hypoglycemic agent that is metabolized in the liver to 1-hydrohexamide. Acetohexamide has been discontinued in the US market.
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-((p-Acetylphenyl)sulfonyl)-3-cyclohexylurea ... N-(p-Acetylphenylsulfonyl)-N'-cyclohexylurea …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates …

Clomifene

A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.
Approved
Investigational
Matched Synonyms: … 2-(p-(β-chloro-α-phenylstyryl)phenoxy)triethylamine ... 2-(p-(2-chloro-1,2-diphenylvinyl)phenoxy)triethylamine …
Matched Categories: … P-glycoprotein substrates …

Formoterol

Formoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001. It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic mixture of its active (R;R)- and inactive (S;S)-enantiomers....
Approved
Investigational
Matched Synonyms: … 2'-hydroxy-5'-(1-hydroxy-2-((p-methoxy-α-methylphenethyl)amino)ethyl)formanilide ... 2'-hydroxy-5'-{1-hydroxy-2-[(p-methoxy-α-methylphenethyl)amino]ethyl}formanilide …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2A6 Substrates ... Cytochrome P-450 CYP2C9 Substrates ... Cytochrome P-450 CYP2D6 Substrates ... Cytochrome P-450 CYP2C19 Substrates …
Matched Products: … FORADIL P + 1 INHALATOR ... FORADIL P + 3 INHALATOR ... FORADIL P + 3 INHALATOREN …

Buclizine

Buclizine is an antihistamine medication with both antiemetic and anticholinergic effects , belonging to the piperazine derivative family of drugs. It was manufactured by Stuart Pharms and initially approved by the FDA in 1957. Following this, it was touted to be effective as an appetite stimulant in children when administered...
Approved
Matched Synonyms: … 1-(p-tert-Butylbenzyl)-4-(4-chloro-alpha-phenylbenzyl)piperazine …

Clemastine

An ethanolamine-derivative, first generation histamine H1 antagonist used in hay fever, rhinitis, allergic skin conditions, and pruritus. It causes drowsiness.
Approved
Investigational
Matched Synonyms: … (+)-(2R)-2-(2-(((R)-p-chloro-α-methyl-α-phenylbenzyl)oxy)ethyl)-1-methylpyrrolidine ... (+)-(2R)-2-[2-[[(R)-p-chloro-α-methyl-α-phenylbenzyl]oxy]ethyl]-1-methylpyrrolidine …
Matched Categories: … Cytochrome P-450 CYP2D6 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP2D6 Inhibitors (strength unknown) …
Displaying drugs 1 - 25 of 7273 in total