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Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays...
Approved
Investigational
Nutraceutical
Vet approved
Matched Synonyms: … Thiamin ... Thiamine ... Thiaminum
Matched Name: … Thiamine
Matched Description: … Thiamine plays a key role in intracellular glucose metabolism and it is thought that thiamine inhibits ... It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. ... Thiamine plays an important role in helping the body convert carbohydrates and fat into energy. …
Matched Mixtures name: … Thiamine HCl 100mg W C 20mg ... Multi Vitamin and Mineral vitamin ... Multi Vitamin and Fluoride …
Matched Salts name: … Thiamine hydrochloride ... Thiamine chloride ... Thiamine mononitrate …
Matched Categories: … thiamine (vit B1) ... Diet, Food, and Nutrition ... Alimentary Tract and Metabolism …
Matched Products: … Thiamine Hydrochloride ... Thiamine Hydrochloride Inj 100mg/ml ... Thiamine Hydrochloride Inj 100mg/ml USP …
Hexaminolevulinate is an optical imaging drug. In solution form it is instilled intravesically for use with photodynamic blue light cystoscopy as an adjunct to white light cystoscopy. On May 28, 2010, the U.S. Food and Drug Administration (FDA) granted approval for hexaminolevulinate hydrochloride (Cysview for Intravesical Solution, Photocure ASA), as...
Approved
Matched Synonyms: … Hexyl 5-amino-4-oxopentanoate hydrochloride ... Hexyl(5-amino-4-oxopentanoat)-hydrochlorid ... Pentanoic acid, 5-amino-4-oxo-, hexyl ester, hydrochloride
Matched Description: … Food and Drug Administration (FDA) granted approval for hexaminolevulinate hydrochloride (Cysview for …
Matched Salts name: … Hexaminolevulinate hydrochloride
Matched Categories: … Amino Acids, Peptides, and Proteins …
Cyanocobalamin Co-60 is an analog of Vitamin B12 labeled with Co60. Cyanocobalamin Co-60 was used for the diagnosis of pernicious anemia, but now it is withdrawn from the market in the US for unknown reasons.
Approved
Withdrawn
Matched Synonyms: … Cyanocobalamin (60Co) ... Cyanocobalamin Co 60 ... Cyanocobalamine (60 Co) …
Matched Name: … Cyanocobalamin Co-60 …
Matched Description: … Cyanocobalamin Co-60 is an analog of Vitamin B12 labeled with Co60. ... Cyanocobalamin Co-60 was used for the diagnosis of pernicious anemia, but now it is withdrawn from the …
Pyridoxine is the 4-methanol form of vitamin B6, an important water-soluble vitamin that is naturally present in many foods. As its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required for normal functioning of many biological systems within the body. While many plants and microorganisms are...
Approved
Investigational
Nutraceutical
Vet approved
Matched Synonyms: … Pyridoxine ... Pyridoxinum
Matched Name: … Pyridoxine
Matched Description: … , pyridoxal, and pyridoxamine, and their phosphorylated derivatives, pyridoxine 5'-phosphate, pyridoxal ... 5'-phosphate and pyridoxamine 5'-phosphate. ... As its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required …
Matched Mixtures name: … Levomefolate Calcium, Cyanocobalamin and Pyridoxine Hydrochloride ... Doxylamine succinate and pyridoxine hydrochloride ... Doxylamine succinate and pyridoxine hydrochloride
Matched Salts name: … Pyridoxine hydrochloride
Matched Categories: … isoniazid, sulfamethoxazole, trimethoprim and pyridoxine ... pyridoxine (vit B6) ... Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Products: … Pyridoxine Hydrochloride ... Pyridoxine Hydrochloride Injection, USP ... Pyridoxine Hydrochloride Injection 100mg/ml …
Approved
Matched Synonyms: … Cyanocobalamin Co 57 ... Cyanocobalamin (57Co) ... Cyanocobalamin (57 Co) …
Matched Name: … Cyanocobalamin Co-57 …
Cyanocobalamin (commonly known as Vitamin B12) is a highly complex, essential vitamin, owing its name to the fact that it contains the mineral, cobalt. This vitamin is produced naturally by bacteria , and is necessary for DNA synthesis and cellular energy production. Vitamin B12 has many forms, including the cyano-,...
Approved
Nutraceutical
Matched Synonyms: … Cyanocobalamin ... Cyanocobalamine ... Cyanocobalaminum
Matched Name: … Cyanocobalamin
Matched Description: … This vitamin is produced naturally by bacteria [A175276], and is necessary for DNA synthesis and cellular ... Cyanocobalamin (commonly known as Vitamin B12) is a highly complex, essential vitamin, owing its name ... and nasal spray forms [FDA label], [L5542], [L5545]. …
Matched Mixtures name: … Levomefolate Calcium, Cyanocobalamin and Pyridoxine Hydrochloride ... and Succinic Acid ... Multi Vitamin and Fluoride …
Matched Categories: … cyanocobalamin ... cyanocobalamin, combinations ... Diet, Food, and Nutrition ... Blood and Blood Forming Organs ... Vitamin B12 and Folic Acid …
Matched Products: … Cyanocobalamin ... Cyancobalamin ... Cyanocobalamine
A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category. It is also considered to be among the safest for patients with hypertension. (From AMA Drug Evaluations Annual, 1994, p2290)
Approved
Illicit
Matched Salts name: … Diethylpropion hydrochloride
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Diethylpropion Hydrochloride ... Diethylpropion Hydrochloride ER ... Diethylpropion HydrochlorideER ER …
Bupropion (also known as the brand name product Wellbutrin®) is a norepinephrine/dopamine-reuptake inhibitor (NDRI) used most commonly for the management of Major Depressive Disorder (MDD), Seasonal Affective Disorder (SAD), and as an aid for smoking cessation. Bupropion exerts its pharmacological effects by weakly inhibiting the enzymes involved in the uptake...
Approved
Matched Description: … commonly for the management of Major Depressive Disorder (MDD), Seasonal Affective Disorder (SAD), and ... from the synaptic cleft, therefore prolonging their duration of action within the neuronal synapse and ... More specifically, bupropion binds to the norepinephrine transporter (NET) and the dopamine transporter …
Matched Mixtures name: … Naltrexone Hydrochloride and Bupropion Hydrochloride Extended-Release …
Matched Salts name: … Bupropion hydrochloride
Matched Categories: … bupropion and naltrexone ... bupropion and dextromethorphan ... Dopamine And Norepinephrine Reuptake Inhibitors ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … Bupropion Hydrochloride ... BuPROPion Hydrochloride ... Bupropion Hydrochloride XL …
One of the catecholamine neurotransmitters in the brain. It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (receptors, dopamine) mediate its action.
Approved
Matched Description: … It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. ... Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating …
Matched Mixtures name: … Dopamine Hydrochloride and 5% Dextrose Injection USP ... Dopamine Hydrochloride and 5% Dextrose Injection USP ... Dopamine Hydrochloride and 5% Dextrose Injection USP …
Matched Salts name: … Dopamine hydrochloride
Matched Categories: … Adrenergic and Dopaminergic Agents …
Matched Products: … DOPamine Hydrochloride and Dextrose ... Dopamine Hydrochloride and Dextrose ... DOPamine HYDROCHLORIDE AND DEXTROSE …
Approved
Experimental
Matched Synonyms: … Zirconium hydroxychloride ... Zirconyl hydroxychloride
A pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with...
Approved
Matched Description: … Negative potential reduces secretion of potassium and hydrogen ions. ... (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705) ... negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and
Matched Mixtures name: … Amiloride Hydrochloride and Hydrochlorothiazide ... Amiloride Hydrochloride and Hydrochlorothiazide ... Amiloride Hydrochloride and Hydrochlorothiazide …
Matched Salts name: … Amiloride hydrochloride ... Amiloride hydrochloride dihydrate …
Matched Products: … Amiloride Hydrochloride ... Amiloride Hydrocloride ... Amiloride Hydrochloride Tablets, USP …
Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric...
Approved
Investigational
Matched Description: … Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. …
Matched Salts name: … Trimethobenzamide hydrochloride
Matched Products: … Trimethobenzamide Hydrochloride ... Trimethobenzamide hydrochloride ... Trimethobenzamide Hydorchloride
Experimental
Matched Name: … Magnesium aspartate hydrochloride
Matched Iupac: … magnesium(2+) (2S)-2-aminobutanedioate hydrochloride
Matched Salts name: … Magnesium aspartate hydrochloride trihydrate …
Loperamide is an anti-diarrheal agent that is available as various over-the-counter products for treating diarrhea. The drug was first synthesized in 1969 and used medically in 1976. It is a highly lipophilic synthetic phenylpiperidine opioid that is structurally similar to opiate receptor agonists such as diphenoxylate and haloperidol. Due to...
Approved
Matched Description: … withdrawal symptoms and to induce euphoria. ... [L42785] The drug was first synthesized in 1969 and used medically in 1976. ... [A6249] Due to pharmacological properties, loperamide has been misused and abused to self-manage opioid …
Matched Mixtures name: … Loperamide Hydrochloride and Simethicone ... Loperamide Hydrochloride and Simethicone ... Loperamide Hydrochloride and Simethicone …
Matched Salts name: … Loperamide hydrochloride
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up anti diarrheal ... Berkley and Jensen Anti Diarrheal ... Foster and Thrive Anti-diarrheal …
Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s. Phenylephrine was granted FDA approval in 1939.
Approved
Matched Description: … alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil,[L9413] and
Matched Mixtures name: … Promethazine Hydrochloride and Phenylephrine Hydrochloride ... Promethazine Hydrochloride and Phenylephrine Hydrochloride ... Promethazine Hydrochloride and Phenylephrine Hydrochloride
Matched Salts name: … Phenylephrine hydrochloride
Matched Categories: … Adrenergic and Dopaminergic Agents ... Mydriatics and Cycloplegics ... phenylephrine and ketorolac ... Decongestants and Antiallergics ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Up and Up Sinus PE ... CareOne Cold and Sinus ... Phenylephrine hydrochloride
Cetirizine, also commonly known as Zyrtec, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and other symptoms , . One of the most common uses for this drug is for a condition called allergic...
Approved
Matched Description: … in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and ... with sleep, and other difficulties with day to day activities for many individuals [A175057]. ... prevalence of allergic rhinitis in the United States is about 15% according to physician diagnoses, and
Matched Mixtures name: … Cetirizine Hydrochloride and Pseudoephedrine Hydrochloride ... Cetirizine Hydrochloride and Pseudoephedrine Hydrochloride ... Cetirizine Hydrochloride and Pseudoephedrine Hydrochloride
Matched Salts name: … Cetirizine hydrochloride
Matched Categories: … Cetirizine and isomer ... Decongestants and Antiallergics …
Matched Products: … Berkley and Jensen Cetirizine Hydrochloride ... Berkley and Jensen Childrens Cetirizine Hydrochloride ... Up and Up Allergy Relief …
Meclizine is a histamine H1 antagonist with antiemetic and antivertigo properties. It is used in the symptomatic treatment of motion sickness and control of vertigo associated with vestibular system diseases. It also exhibits anticholinergic, central nervous system depressant, and local anesthetic effects. Commonly marketed under the brand name Antivert in...
Approved
Matched Description: … Meclizine is a histamine H1 antagonist with antiemetic and antivertigo properties. ... It also exhibits anticholinergic, central nervous system depressant, and local anesthetic effects. ... It is used in the symptomatic treatment of motion sickness and control of vertigo associated with vestibular …
Matched Salts name: … Meclizine hydrochloride
Matched Products: … Meclizine Hydrochloride ... Meclizine Hydrocloride ... Meclizine hydrochloride
Experimental
Matched Synonyms: … Hydrochloric acid …
Matched Name: … Hydrochloric acid …
Matched Categories: … hydrochloric acid ... hydrochloric acid ... Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up 25% of the mixture. Labetalol is formulated as an injection or tablets to treat hypertension.[L7727,L7730] Labetalol was granted FDA approval on 1 August 1984.
Approved
Matched Salts name: … Labetalol hydrochloride
Matched Categories: … Alpha and Beta Blocking Agents and Thiazides ... Alpha and Beta Blocking Agents ... labetalol and thiazides ... labetalol and other diuretics ... Beta Blocking Agents and Thiazides …
Matched Products: … BLOCAMINE (Labetalol hydrochloride 5 mg/ml solution for Injection and for Infusion) ... Labetalol Hydrochloride ... Labetalol hydrochloride
Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and was soon repurposed. Hydralazine is a hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and only as adjunct therapy in the treatment of heart failure.[A186820,L8782,L8785] Hydralazine is no longer a...
Approved
Matched Description: … [T691] Hydralazine hydrochloride was FDA approved on 15 January 1953.[L8779] ... Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and ... hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and
Matched Mixtures name: … Isosorbide dinitrate and hydralazine hydrochloride ... Isosorbide Dinitrate and Hydralazine Hydrochloride ... Isosorbide Dinitrate and Hydralazine Hydrochloride
Matched Salts name: … Hydralazine hydrochloride
Matched Categories: … hydralazine and diuretics ... Hydrazinophthalazine Derivatives and Diuretics …
Matched Products: … Hydralazine Hydrochloride ... HydrALAZINE Hydrochloride ... Apresoline hydrochloride
Methadone is a potent synthetic analgesic that works as a full µ-opioid receptor (MOR) agonist and N-methyl-d-aspartate (NMDA) receptor antagonist. As a full MOR agonist, methadone mimics the natural effects of the body's opioids, endorphins, and enkephalins through the release of neurotransmitters involved in pain transmission. It also has a...
Approved
Matched Description: … of serotonin and norepinephrine uptake. ... [hydromorphone], [oxycodone], and [fentanyl]. ... comparatively longer duration of action and half-life. …
Matched Salts name: … Methadone hydrochloride
Matched Products: … Methadone Hydrochloride ... Methadone hydrochloride ... Methadone Hydrocloride
A local anesthetic that is chemically related to bupivacaine but pharmacologically related to lidocaine. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
Approved
Vet approved
Matched Description: … It is indicated for infiltration, nerve block, and epidural anesthesia. ... Mepivacaine is effective topically only in large doses and therefore should not be used by this route …
Matched Mixtures name: … Mepivacaine Hydrochloride and Levonordefrin ... Mepivacaine Hydrochloride with Levonordefrin …
Matched Salts name: … Mepivacaine hydrochloride
Matched Products: … Mepivacaine Hydrochloride ... MEPIVACAINE HYDROCHLORIDE 1% ... MEVIPACAINE HYDROCHLORIDE 1% * 5ML …
Fexofenadine is an over-the-counter second-generation antihistamine used in the treatment of various allergic symptoms. It is selective for the H1 receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier - this is in contrast to previous first-generation antihistamines, such as diphenhydramine, which readily bind to off-targets...
Approved
Investigational
Matched Description: … L4269] It is selective for the H1 receptor, carries little-to-no activity at off-targets, and ... [A1452] Fexofenadine is the major active metabolite of [terfenadine][A1495] and is administered as a …
Matched Mixtures name: … FEXOFENADINE HYDROCHLORIDE and PSEUDOEPHEDRINE HYDROCHLORIDE ... FEXOFENADINE HYDROCHLORIDE and PSEUDOEPHEDRINE HYDROCHLORIDE ... FEXOFENADINE HYDROCHLORIDE and PSEUDOEPHEDRINE HYDROCHLORIDE
Matched Salts name: … Fexofenadine hydrochloride
Matched Products: … Up and Up Allergy Relief ... Berkley and Jensen Allergy Relief ... Up and Up Non Drowsy Allergy Relief …
Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions. It is a structural analog of doxepin, which has a minimal anti-allergic activity. Olopatadine works by blocking the effects of histamine, which is a primary inflammatory mediator that causes inflammatory and...
Approved
Matched Description: … seasonal and perennial allergic conjunctivitis in 1996 and 2002, respectively. ... inflammatory and allergic reactions. ... Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating …
Matched Salts name: … Olopatadine hydrochloride
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Eye Allergy Itch and Redness Relief ... Eye Allergy Itch and Redness Relief Twice Daily Relief ... Olopatadine Hydrochloride
Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system.[A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. The decongestant effect of pseudoephedrine was described...
Approved
Matched Description: … drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and
Matched Mixtures name: … FEXOFENADINE HYDROCHLORIDE and PSEUDOEPHEDRINE HYDROCHLORIDE ... FEXOFENADINE HYDROCHLORIDE and PSEUDOEPHEDRINE HYDROCHLORIDE ... FEXOFENADINE HYDROCHLORIDE and PSEUDOEPHEDRINE HYDROCHLORIDE
Matched Salts name: … Pseudoephedrine hydrochloride
Matched Categories: … Alpha-and Beta-adrenergic Agonists …
Matched Products: … Pseudoephedrine Hydrochloride ... Pseudoephedrine hydrochloride ... Pseudoephedrine Hydrochloride Srt 120mg Tab …
Displaying drugs 1 - 25 of 675 in total