Corticosteroid-binding globulin

BE0000209ProteinHumansSERPINA6

Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species. It is acted on by 46 drugs in DrugBank.

Gene name
SERPINA6
UniProtKB entry
P08185Swiss-Prot
Cellular location
Secreted
Residues / weight
405 residues · 45,140 Da
Also known as
CBG · Serpin A6 · Transcortin

Resolves to

Protein
UniProtP08185UniProt nameCBG_HUMAN
Gene
HGNCHGNC:1540NCBI Gene866GenBank179971GeneCardsSERPINA6
Pharmacology
KEGGhsa:866
Structure
PDB2VDXPDB2VDYPDB4BB2
Drugs

What you can answer from here — as of September 07, 2019

46DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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85+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Corticosteroid-binding globulin, how selective are they, and which programs against it are still in active trials?

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