Accession Number

A group of CORTICOSTEROIDS primarily associated with water and electrolyte balance. This is accomplished through the effect on ION TRANSPORT in renal tubules, resulting in retention of sodium and loss of potassium. Mineralocorticoid secretion is itself regulated by PLASMA VOLUME, serum potassium, and ANGIOTENSIN II.

ATC Classification
DrugDrug Description
Desoxycorticosterone acetateNot Annotated
FludrocortisoneA mineralocorticoid used to treat adrenocortical insufficiency and salt-losing adrenogenital syndrome.
AldosteroneA hormone secreted by the adrenal cortex that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.
DesoxycortoneNot Annotated
Drugs & Drug Targets
Desoxycorticosterone acetateMineralocorticoid receptortarget
Desoxycorticosterone acetateCytochrome P450 3A4enzyme
FludrocortisoneMineralocorticoid receptortarget
FludrocortisoneGlucocorticoid receptortarget
FludrocortisoneCytochrome P450 3A4enzyme
FludrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
FludrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
FludrocortisoneSerum albumincarrier
FludrocortisoneCorticosteroid-binding globulincarrier
AldosteroneMineralocorticoid receptortarget
AldosteroneP-glycoprotein 1transporter
AldosteroneSolute carrier family 22 member 5transporter
AldosteroneSolute carrier organic anion transporter family member 1A2transporter
AldosteroneCytochrome P450 11B1, mitochondrialenzyme
AldosteroneCytochrome P450 11B2, mitochondrialenzyme
AldosteroneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
AldosteroneGlucocorticoid receptortarget
AldosteroneCytochrome P450 3A4enzyme