Xanthine Oxidase Inhibitors
- Xanthine Oxidase Inhibitors
- Accession Number
- DBCAT002773 (DBCAT002774, DBCAT002775, DBCAT003814)
An xanthine oxidase inhibitor is any substance that inhibits the activity of xanthine oxidase, an enzyme involved in purine metabolism. In humans, inhibition of xanthine oxidase reduces the production of uric acid, and several medications that inhibit xanthine oxidase are indicated for treatment of hyperuricemia and related medical conditions including gout.
Drug Drug Description Allopurinol A xanthine oxidase inhibitor used to reduce urinary and serum uric acid concentrations in patients with gout, recurrent calcium oxalate calculi, and various malignancies. Febuxostat A xanthine oxidase inhibitor used for the management of chronic hyperuricemia in adults with gout who have an inadequate response or intolerance to allopurinol. Oxypurinol Intended for the treatment of congestive heart failure and hyperuricemia.
- Drugs & Drug Targets